The impacts of pesticide exposure on fish conspecific behavioural interactions: a systematic review and meta-analysis
Kyle Morrison, Aneesh Bose, Rhiannon Eastment, Jack Manera, Gabriel Melhado, Marcus Michelangeli, Shiho Ozeki, Bob Wong, Yefeng Yang, Malgorzata Lagisz, Shinichi Nakagawa
latest update: 06 September 2024
Load packages and data
Load packages
Load Data
data <- read_csv(here("data", "fish_conspecific_behaviour_ma_data.csv"), skip = 0)
# Format ID variables as characters
data <- mutate_at(data, vars(study_id, exp_id, exp2_id, assay_id, assay2_id), as.character)
# Table of the dataset
kable(data, "html") %>%
kable_styling("bordered", position = "left") %>%
scroll_box(width = "250%", height = "800px")| comment_checker | comment_extractor | initials_checker | initials_extractor | title | doi | url | journal | study_id | exp_id | exp2_id | assay_id | assay2_id | species_english | species_latin | source | source2 | sex | pesticide | pesticide_grade | cas_id | cas_id_comment | pesticide_chemical_class | dosage | dosage_unit | duration | duration_unit | control_solvent | solvent2 | temperature | temperature_unit | behaviour_measured | behaviour_measured_standardised | behaviour_assay | behavioural_assay_standardised | behavioural_assay_standardised2 | effect_direction | data_source | data_file | control_effective_n | control_shoal_n | control_fish_n | control_n | control_mean | control_sd | control_shoal_sd | control_fish_sd | control_se | statistics_comment_control | sample_size_comment_control | treatment_effective_n | treatment_shoal_n | treatment_fish_n | treatment_n | treatment_mean | treatment_sd | treatment_shoal_sd | treatment_fish_sd | treatment_se | statistics_comment_treatment | sample_size_comment_treatment | contact_author | contacted_date | contact_response | contact_comments |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NA | NA | NA | KM | From dysbiosis to neuropathologies: Toxic effects of glyphosate in zebrafish | 10.1016/j.ecoenv.2023.115888 | https://www.sciencedirect.com/science/article/pii/S0147651323013921 | Ecotoxicology and Environmental Safety | bellot_2024 | bellot_2024_exp_001 | bellot_2024_exp2_001 | bellot_2024_exp_001_assay_001 | bellot_2024_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | analytical | 1071<96>83-6 | in paper | organophosphate | 0.3 | ug/L | 2 | weeks | not reported | NA | 28.5 | celsius | social interaction | sociality | time spent in conspecific zone | time spent in social zone | zone | NA | fig4 | bellot_2024_fig4 | NA | NA | NA | 15 | 61.0344828 | 19.7736111 | NA | NA | 5.105524437 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | 16 | 45.6896552 | 11.2390246 | NA | NA | 2.809756146 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| NA | NA | NA | KM | From dysbiosis to neuropathologies: Toxic effects of glyphosate in zebrafish | 10.1016/j.ecoenv.2023.115888 | https://www.sciencedirect.com/science/article/pii/S0147651323013921 | Ecotoxicology and Environmental Safety | bellot_2024 | bellot_2024_exp_002 | bellot_2024_exp2_002 | bellot_2024_exp_002_assay_001 | bellot_2024_exp2_002_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | analytical | 1071<96>83-6 | in paper | organophosphate | 3 | ug/L | 2 | weeks | not reported | NA | 28.5 | celsius | social interaction | sociality | time spent in conspecific zone | time spent in social zone | zone | NA | fig4 | bellot_2024_fig4 | NA | NA | NA | 15 | 61.0344828 | 19.7736111 | NA | NA | 5.105524437 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | 16 | 45.2945402 | 15.0522332 | NA | NA | 3.763058307 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| NA | NA | SN | KM | Diuron metabolites act as endocrine disruptors and alter aggressive behavior in Nile tilapia (Oreochromis niloticus) | 10.1016/j.chemosphere.2017.10.009 | https://www.sciencedirect.com/science/article/pii/S0045653517315801?via%3Dihub | Chemosphere | boscolo_2018 | boscolo_2018_exp_001 | boscolo_2018_exp2_001 | boscolo_2018_exp_001_assay_001 | boscolo_2018_exp2_001_assay2_001 | Nile tilapia | Oreochromis niloticus | laboratory stock from not specified source | not_wild | male | diuron | not reported | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 100 | ng/L | 10 | days | acetone | solvent_used | 27 | celsius | aggression | aggression | total frequency of aggressive interactions | frequency of aggressive behaviour | count | NA | fig2 | boscolo_2019_fig2 | NA | NA | NA | 12 | 41.8874519 | 35.5260736 | NA | NA | 10.25549408 | study reports mean and se | exact sample size provided | NA | NA | NA | 12 | 44.3101781 | 35.3497491 | NA | NA | 10.20459358 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Diuron metabolites act as endocrine disruptors and alter aggressive behavior in Nile tilapia (Oreochromis niloticus) | 10.1016/j.chemosphere.2017.10.009 | https://www.sciencedirect.com/science/article/pii/S0045653517315801?via%3Dihub | Chemosphere | boscolo_2018 | boscolo_2018_exp_002 | boscolo_2018_exp2_002 | boscolo_2018_exp_002_assay_001 | boscolo_2018_exp2_002_assay2_001 | Nile tilapia | Oreochromis niloticus | laboratory stock from not specified source | not_wild | male | DCPMU | not reported | 3567-62-2 | https://commonchemistry.cas.org/detail?cas_rn=3567-62-2&search=DCPMU | urea | 100 | ng/L | 10 | days | acetone | solvent_used | 27 | celsius | aggression | aggression | total frequency of aggressive interactions | frequency of aggressive behaviour | count | NA | fig2 | boscolo_2019_fig2 | NA | NA | NA | 12 | 41.8874519 | 35.5260736 | NA | NA | 10.25549408 | study reports mean and se | exact sample size provided | NA | NA | NA | 12 | 20.7776130 | 13.7057934 | NA | NA | 3.956521739 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Diuron metabolites act as endocrine disruptors and alter aggressive behavior in Nile tilapia (Oreochromis niloticus) | 10.1016/j.chemosphere.2017.10.009 | https://www.sciencedirect.com/science/article/pii/S0045653517315801?via%3Dihub | Chemosphere | boscolo_2018 | boscolo_2018_exp_003 | boscolo_2018_exp2_003 | boscolo_2018_exp_003_assay_001 | boscolo_2018_exp2_003_assay2_001 | Nile tilapia | Oreochromis niloticus | laboratory stock from not specified source | not_wild | male | DCA | not reported | NA | NA | urea | 100 | ng/L | 10 | days | acetone | solvent_used | 27 | celsius | aggression | aggression | total frequency of aggressive interactions | frequency of aggressive behaviour | count | NA | fig2 | boscolo_2019_fig2 | NA | NA | NA | 12 | 41.8874519 | 35.5260736 | NA | NA | 10.25549408 | study reports mean and se | exact sample size provided | NA | NA | NA | 12 | 13.5725886 | 8.9533703 | NA | NA | 2.584615385 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_001 | bridi_2017_exp2_001 | bridi_2017_exp_001_assay_001 | bridi_2017_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.01 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 91.1310966 | 29.3484305 | NA | NA | 5.755700754 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_002 | bridi_2017_exp2_002 | bridi_2017_exp_002_assay_001 | bridi_2017_exp2_002_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.065 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 93.3694247 | 35.0550697 | NA | NA | 6.874864789 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_003 | bridi_2017_exp2_003 | bridi_2017_exp_003_assay_001 | bridi_2017_exp2_003_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.5 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 93.5293053 | 39.9464748 | NA | NA | 7.834148248 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_004 | bridi_2017_exp2_004 | bridi_2017_exp_004_assay_001 | bridi_2017_exp2_004_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.01 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 85.8550376 | 17.9351520 | NA | NA | 3.517372683 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_005 | bridi_2017_exp2_005 | bridi_2017_exp_005_assay_001 | bridi_2017_exp2_005_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.065 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 86.3346793 | 37.5007722 | NA | NA | 7.354506518 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_006 | bridi_2017_exp2_006 | bridi_2017_exp_006_assay_001 | bridi_2017_exp2_006_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | time spent close to stimulus | time spent in aggression zone | zone | NA | fig6a | bridi_2017_fig6a | NA | NA | NA | 26 | 122.2071971 | 28.8770683 | NA | NA | 5.663259022 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 94.6484693 | 16.3046836 | NA | NA | 3.19761153 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_001 | bridi_2017_exp2_001 | bridi_2017_exp_001_assay_002 | bridi_2017_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.01 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 27.7557133 | 10.6687460 | NA | NA | 2.092313231 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_002 | bridi_2017_exp2_002 | bridi_2017_exp_002_assay_002 | bridi_2017_exp2_002_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.065 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 24.8235417 | 12.7349286 | NA | NA | 2.497524975 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_003 | bridi_2017_exp2_003 | bridi_2017_exp_003_assay_002 | bridi_2017_exp2_003_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | glyphosate | not reported | 1071-83-6 | https://commonchemistry.cas.org/detail?cas_rn=1071-83-6&search=GLYPHOSATE | organophosphate | 0.5 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 21.9990956 | 6.1678357 | NA | NA | 1.209612096 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_004 | bridi_2017_exp2_004 | bridi_2017_exp_004_assay_002 | bridi_2017_exp2_004_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.01 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 24.8335687 | 9.4773286 | NA | NA | 1.858657048 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_005 | bridi_2017_exp2_005 | bridi_2017_exp_005_assay_002 | bridi_2017_exp2_005_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.065 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 23.4381956 | 6.6910003 | NA | NA | 1.312213122 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Glyphosate and Roundup<ae><a0>alter morphology and behavior in zebrafish | 10.1016/j.tox.2017.10.007 | https://www.sciencedirect.com/science/article/pii/S0300483X17303128?via%3Dihub | Toxicology | bridi_2017 | bridi_2017_exp_006 | bridi_2017_exp2_006 | bridi_2017_exp_006_assay_002 | bridi_2017_exp2_006_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 96 | hours | none | none | 26 | celsius | aggression | aggression | number of enteries | frequency of entries into aggression zone | entry | NA | fig6b | bridi_2017_fig6b | NA | NA | NA | 26 | 39.4858436 | 18.8042738 | NA | NA | 3.687821494 | study reports mean and se | exact sample size provided | NA | NA | NA | 26 | 24.7084876 | 5.8935449 | NA | NA | 1.155819251 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_001 | chen_2022_exp2_001 | chen_2022_exp_001_assay_001 | chen_2022_exp2_001_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 0.1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4a | chen_2022_fig4a | NA | NA | NA | 8 | 180.9746781 | 23.4351145 | NA | NA | 8.285564192 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 126.7255128 | 19.8473282 | NA | NA | 7.017090195 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_002 | chen_2022_exp2_002 | chen_2022_exp_002_assay_001 | chen_2022_exp2_002_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4a | chen_2022_fig4a | NA | NA | NA | 8 | 180.9746781 | 23.4351145 | NA | NA | 8.285564192 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 189.5675534 | 61.7124682 | NA | NA | 21.81865237 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_003 | chen_2022_exp2_003 | chen_2022_exp_003_assay_001 | chen_2022_exp2_003_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 10 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4a | chen_2022_fig4a | NA | NA | NA | 8 | 180.9746781 | 23.4351145 | NA | NA | 8.285564192 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 68.4861285 | 27.3409669 | NA | NA | 9.666491557 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_001 | chen_2022_exp2_001 | chen_2022_exp_001_assay_002 | chen_2022_exp2_001_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 0.1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4b | chen_2022_fig4b | NA | NA | NA | 8 | 199.3015298 | 29.6565579 | NA | NA | 10.4851766 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 195.5944600 | 41.4517798 | NA | NA | 14.6554173 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_002 | chen_2022_exp2_002 | chen_2022_exp_002_assay_002 | chen_2022_exp2_002_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4b | chen_2022_fig4b | NA | NA | NA | 8 | 199.3015298 | 29.6565579 | NA | NA | 10.4851766 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 194.2464347 | 23.2534374 | NA | NA | 8.221331654 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_003 | chen_2022_exp2_003 | chen_2022_exp_003_assay_002 | chen_2022_exp2_003_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 10 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4b | chen_2022_fig4b | NA | NA | NA | 8 | 199.3015298 | 29.6565579 | NA | NA | 10.4851766 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 222.5549672 | 34.3746467 | NA | NA | 12.15327288 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_001 | chen_2022_exp2_001 | chen_2022_exp_001_assay_003 | chen_2022_exp2_001_assay2_003 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 0.1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4c | chen_2022_fig4c | NA | NA | NA | 8 | 145.9508599 | 5.3249169 | NA | NA | 1.882642423 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 122.1935383 | 25.8053665 | NA | NA | 9.123574818 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_002 | chen_2022_exp2_002 | chen_2022_exp_002_assay_003 | chen_2022_exp2_002_assay2_003 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 1 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4c | chen_2022_fig4c | NA | NA | NA | 8 | 145.9508599 | 5.3249169 | NA | NA | 1.882642423 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 137.5538755 | 11.6738563 | NA | NA | 4.127331465 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior | 10.1016/j.scitotenv.2022.155610 | https://www.sciencedirect.com/science/article/pii/S0048969722027061?via%3Dihub | Science of The Total Environment | chen_2022 | chen_2022_exp_003 | chen_2022_exp2_003 | chen_2022_exp_003_assay_003 | chen_2022_exp2_003_assay2_003 | zebrafish | Danio rerio | not reported | NA | mixed | difenoconazole | analytical | 119446-68-3 | in paper | dioxolanes | 10 | ug/L | 120 | days | acetone | solvent_used | not reported | not reported | reproductive behaviour | courtship | contact time | time spent near potential mate | NA | NA | fig4c | chen_2022_fig4c | NA | NA | NA | 8 | 145.9508599 | 5.3249169 | NA | NA | 1.882642423 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | 8 | 108.0620281 | 4.7105034 | NA | NA | 1.665414451 | study reports mean and sd | states four male and four female per tank (section 2.6. Analysis of reproductive behaviour) | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_001 | chung_2023_exp2_001 | chung_2023_exp_001_assay_001 | chung_2023_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 0.1 | ppm | 5 | days | none | none | 25 | celsius | heterosexual attraction | courtship | distance between male and female | distance between potential mates | NA | change | fig5c | chung_2023_fig5c | NA | NA | NA | 10 | 4.4371410 | 1.8613055 | NA | NA | 0.588596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 10.2614352 | 4.7267729 | NA | NA | 1.494736842 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_002 | chung_2023_exp2_002 | chung_2023_exp_002_assay_001 | chung_2023_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 0.5 | ppm | 5 | days | none | none | 25 | celsius | heterosexual attraction | courtship | distance between male and female | distance between potential mates | NA | change | fig5c | chung_2023_fig5c | NA | NA | NA | 10 | 4.4371410 | 1.8613055 | NA | NA | 0.588596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 11.4526297 | 4.9691449 | NA | NA | 1.571381579 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_003 | chung_2023_exp2_003 | chung_2023_exp_003_assay_001 | chung_2023_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 1 | ppm | 5 | days | none | none | 25 | celsius | heterosexual attraction | courtship | distance between male and female | distance between potential mates | NA | change | fig5c | chung_2023_fig5c | NA | NA | NA | 10 | 4.4371410 | 1.8613055 | NA | NA | 0.588596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 14.6312253 | 4.9212946 | NA | NA | 1.55625 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_001 | chung_2023_exp2_004 | chung_2023_exp_001_assay_002 | chung_2023_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 0.1 | ppm | 5 | days | none | none | 25 | celsius | defensive alert behaviour | aggression | male confrontation distance | confrontation distance | NA | change | fig6c | chung_2023_fig6c | NA | NA | NA | 10 | 16.5992051 | 4.9695724 | NA | NA | 1.571516773 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 13.4650111 | 4.9152299 | NA | NA | 1.554332167 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_002 | chung_2023_exp2_005 | chung_2023_exp_002_assay_002 | chung_2023_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 0.5 | ppm | 5 | days | none | none | 25 | celsius | defensive alert behaviour | aggression | male confrontation distance | confrontation distance | NA | change | fig6c | chung_2023_fig6c | NA | NA | NA | 10 | 16.5992051 | 4.9695724 | NA | NA | 1.571516773 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 12.3161622 | 4.6034927 | NA | NA | 1.455752212 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Neonicotinoid Imidacloprid Affects the Social Behavior of Adult Zebrafish by Damaging Telencephalon Neurons through Oxidation Stress, Inflammation, and Apoptosis | 10.3390/life13061418<a0> | https://www.mdpi.com/2075-1729/13/6/1418#:~:text=Our%20behavioral%20and%20histological%20experiments,zebrafish%20through%20oxidative%20stress%2C%20inflammation | Life | chung_2023 | chung_2023_exp_003 | chung_2023_exp2_006 | chung_2023_exp_003_assay_002 | chung_2023_exp2_006_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | imidacloprid | analytical | 138261-41-3 | in paper | neonicotinoid | 1 | ppm | 5 | days | none | none | 25 | celsius | defensive alert behaviour | aggression | male confrontation distance | confrontation distance | NA | change | fig6c | chung_2023_fig6c | NA | NA | NA | 10 | 16.5992051 | 4.9695724 | NA | NA | 1.571516773 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 12.3789323 | 4.8273708 | NA | NA | 1.526548673 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety | 10.1016/j.envint.2020.106253 | https://www.sciencedirect.com/science/article/pii/S0278584618306961?via%3Dihub | Progress in Neuro-Psychopharmacology and Biological Psychiatry | faria_2021 | faria_2021_exp_001 | faria_2021_exp2_001 | faria_2021_exp_001_assay_001 | faria_2021_exp_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | glyphosate | analytical | 1071-83-6 | in paper | organophosphate | 0.3 | ug/L | 2 | weeks | not reported | NA | 28 | celsius | shoaling | collective behaviour | average interfish distance | group arrangment | NA | change | fig1ca | faria_2021_fig1ca | 9.500000 | 6.333333 | 19 | 19 | 6.3473684 | 1.9851920 | 1.1461511 | 1.9851920 | 0.455434271 | calculated from scatter plot | counted from the scatter plot | 10.500000 | 7.000000 | 21 | 21 | 4.5980952 | 1.7724774 | 1.0233403 | 1.7724774 | 0.386786282 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety | 10.1016/j.envint.2020.106253 | https://www.sciencedirect.com/science/article/pii/S0278584618306961?via%3Dihub | Progress in Neuro-Psychopharmacology and Biological Psychiatry | faria_2021 | faria_2021_exp_002 | faria_2021_exp2_002 | faria_2021_exp_002_assay_001 | faria_2021_exp_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | glyphosate | analytical | 1071-83-6 | in paper | organophosphate | 3 | ug/L | 2 | weeks | not reported | NA | 28 | celsius | shoaling | collective behaviour | average interfish distance | group arrangment | NA | change | fig1ca | faria_2021_fig1ca | 9.500000 | 6.333333 | 19 | 19 | 6.3473684 | 1.9851920 | 1.1461511 | 1.9851920 | 0.455434271 | calculated from scatter plot | counted from the scatter plot | 9.500000 | 6.333333 | 19 | 19 | 4.1852632 | 1.1541007 | 0.6663204 | 1.1541007 | 0.26476887 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety | 10.1016/j.envint.2020.106253 | https://www.sciencedirect.com/science/article/pii/S0278584618306961?via%3Dihub | Progress in Neuro-Psychopharmacology and Biological Psychiatry | faria_2021 | faria_2021_exp_001 | faria_2021_exp2_001 | faria_2021_exp_001_assay_002 | faria_2021_exp_001_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | glyphosate | analytical | 1071-83-6 | in paper | organophosphate | 0.3 | ug/L | 2 | weeks | not reported | NA | 28 | celsius | shoaling | collective behaviour | farthest distance | group arrangment | NA | change | fig1cb | faria_2021_fig1cb | 10.000000 | 6.666667 | 20 | 20 | 8.9156627 | 3.0988088 | 1.7890981 | 3.0988088 | 0.69291471 | calculated from scatter plot | counted from the scatter plot | 10.000000 | 6.666667 | 20 | 20 | 7.5108434 | 2.4946464 | 1.4402848 | 2.4946464 | 0.557819889 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety | 10.1016/j.envint.2020.106253 | https://www.sciencedirect.com/science/article/pii/S0278584618306961?via%3Dihub | Progress in Neuro-Psychopharmacology and Biological Psychiatry | faria_2021 | faria_2021_exp_002 | faria_2021_exp2_002 | faria_2021_exp_002_assay_002 | faria_2021_exp_002_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | glyphosate | analytical | 1071-83-6 | in paper | organophosphate | 3 | ug/L | 2 | weeks | not reported | NA | 28 | celsius | shoaling | collective behaviour | farthest distance | group arrangment | NA | change | fig1cb | faria_2021_fig1cb | 10.000000 | 6.666667 | 20 | 20 | 8.9156627 | 3.0988088 | 1.7890981 | 3.0988088 | 0.69291471 | calculated from scatter plot | counted from the scatter plot | 9.500000 | 6.333333 | 19 | 19 | 6.3817375 | 1.7880691 | 1.0323422 | 1.7880691 | 0.410211192 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_001 | guo_2023_exp_001_assay_001 | guo_2023_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1a | guo_2023_fig1a | NA | NA | NA | 18 | 1373.4542280 | 409.2070780 | NA | NA | 96.45103324 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1270.4882060 | 381.0371636 | NA | NA | 89.81132075 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_002 | guo_2023_exp_002_assay_001 | guo_2023_exp2_002_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1a | guo_2023_fig1a | NA | NA | NA | 18 | 1373.4542280 | 409.2070780 | NA | NA | 96.45103324 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1158.6011610 | 290.3140294 | NA | NA | 68.42767296 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_003 | guo_2023_exp_003_assay_001 | guo_2023_exp2_003_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1a | guo_2023_fig1a | NA | NA | NA | 18 | 1373.4542280 | 409.2070780 | NA | NA | 96.45103324 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 949.9591025 | 206.1473570 | NA | NA | 48.58939802 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_001 | guo_2023_exp_001_assay_002 | guo_2023_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | entry | NA | fig1b | guo_2023_fig1b | NA | NA | NA | 18 | 309.5539912 | 45.7650012 | NA | NA | 10.78691424 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 297.0195325 | 55.0080310 | NA | NA | 12.96551724 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_002 | guo_2023_exp_002_assay_002 | guo_2023_exp2_002_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | entry | NA | fig1b | guo_2023_fig1b | NA | NA | NA | 18 | 309.5539912 | 45.7650012 | NA | NA | 10.78691424 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 261.8035239 | 61.7302344 | NA | NA | 14.54995579 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_003 | guo_2023_exp_003_assay_002 | guo_2023_exp2_003_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | entry | NA | fig1b | guo_2023_fig1b | NA | NA | NA | 18 | 309.5539912 | 45.7650012 | NA | NA | 10.78691424 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 229.1189647 | 28.2242516 | NA | NA | 6.652519894 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_004 | guo_2023_exp_001_assay_003 | guo_2023_exp2_004_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1c | guo_2023_fig1c | NA | NA | NA | 18 | 1884.3730430 | 237.0771902 | NA | NA | 55.87962963 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1847.5386150 | 344.1253002 | NA | NA | 81.11111111 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_005 | guo_2023_exp_002_assay_003 | guo_2023_exp2_005_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1c | guo_2023_fig1c | NA | NA | NA | 18 | 1884.3730430 | 237.0771902 | NA | NA | 55.87962963 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1630.6968560 | 267.0180022 | NA | NA | 62.93674669 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_006 | guo_2023_exp_003_assay_003 | guo_2023_exp2_006_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | distance in region of attraction | distance in attraction zone | NA | NA | fig1c | guo_2023_fig1c | NA | NA | NA | 18 | 1884.3730430 | 237.0771902 | NA | NA | 55.87962963 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1551.1200200 | 246.3088621 | NA | NA | 58.05555556 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_004 | guo_2023_exp_001_assay_004 | guo_2023_exp2_004_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | NA | NA | fig1d | guo_2023_fig1d | NA | NA | NA | 18 | 409.4204690 | 94.9970023 | NA | NA | 22.39100817 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 350.5993116 | 108.2921041 | NA | NA | 25.52469371 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_005 | guo_2023_exp_002_assay_004 | guo_2023_exp2_005_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | NA | NA | fig1d | guo_2023_fig1d | NA | NA | NA | 18 | 409.4204690 | 94.9970023 | NA | NA | 22.39100817 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 318.4471427 | 45.7307342 | NA | NA | 10.77883742 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_006 | guo_2023_exp_003_assay_004 | guo_2023_exp2_006_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | frequency in region of attraction | frequency of entries into attraction zone | NA | NA | fig1d | guo_2023_fig1d | NA | NA | NA | 18 | 409.4204690 | 94.9970023 | NA | NA | 22.39100817 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 247.1051863 | 37.7633368 | NA | NA | 8.900903843 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_007 | guo_2023_exp_001_assay_005 | guo_2023_exp2_007_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near female | time spent near potential mate | NA | NA | fig3a | guo_2023_fig3a | NA | NA | NA | 18 | 268.9578769 | 75.3692640 | NA | NA | 17.76470588 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 235.1859327 | 23.4864342 | NA | NA | 5.535805627 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_008 | guo_2023_exp_002_assay_005 | guo_2023_exp2_008_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near female | time spent near potential mate | NA | NA | fig3a | guo_2023_fig3a | NA | NA | NA | 18 | 268.9578769 | 75.3692640 | NA | NA | 17.76470588 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 219.6814749 | 10.9266987 | NA | NA | 2.57544757 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_009 | guo_2023_exp_003_assay_005 | guo_2023_exp2_009_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near female | time spent near potential mate | NA | NA | fig3a | guo_2023_fig3a | NA | NA | NA | 18 | 268.9578769 | 75.3692640 | NA | NA | 17.76470588 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 185.9934066 | 29.5411490 | NA | NA | 6.962915601 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_010 | guo_2023_exp_001_assay_006 | guo_2023_exp2_010_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near male | time spent near potential mate | NA | NA | fig3b | guo_2023_fig3b | NA | NA | NA | 18 | 375.9013678 | 57.8482422 | NA | NA | 13.63496144 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 351.1144493 | 10.3830178 | NA | NA | 2.447300771 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_011 | guo_2023_exp_002_assay_006 | guo_2023_exp2_011_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near male | time spent near potential mate | NA | NA | fig3b | guo_2023_fig3b | NA | NA | NA | 18 | 375.9013678 | 57.8482422 | NA | NA | 13.63496144 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 299.3022884 | 25.0850221 | NA | NA | 5.912596401 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_012 | guo_2023_exp_003_assay_006 | guo_2023_exp2_012_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | courting | courtship | time near male | time spent near potential mate | NA | NA | fig3b | guo_2023_fig3b | NA | NA | NA | 18 | 375.9013678 | 57.8482422 | NA | NA | 13.63496144 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 288.2150279 | 37.1258326 | NA | NA | 8.750642674 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_013 | guo_2023_exp_001_assay_007 | guo_2023_exp2_013_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4a | guo_2023_fig4a | NA | NA | NA | 18 | 791.2936092 | 22.3047106 | NA | NA | 5.257270694 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 822.1038557 | 43.8501118 | NA | NA | 10.33557047 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_014 | guo_2023_exp_002_assay_007 | guo_2023_exp2_014_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4a | guo_2023_fig4a | NA | NA | NA | 18 | 791.2936092 | 22.3047106 | NA | NA | 5.257270694 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 835.5618474 | 65.1867030 | NA | NA | 15.36465324 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_015 | guo_2023_exp_003_assay_007 | guo_2023_exp2_015_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4a | guo_2023_fig4a | NA | NA | NA | 18 | 791.2936092 | 22.3047106 | NA | NA | 5.257270694 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 883.1714357 | 53.8160463 | NA | NA | 12.68456376 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_013 | guo_2023_exp_001_assay_008 | guo_2023_exp2_013_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4c | guo_2023_fig4c | NA | NA | NA | 18 | 718.7022832 | 88.9227981 | NA | NA | 20.95930452 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 811.1211318 | 259.4663803 | NA | NA | 61.15681234 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_014 | guo_2023_exp_002_assay_008 | guo_2023_exp2_014_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4c | guo_2023_fig4c | NA | NA | NA | 18 | 718.7022832 | 88.9227981 | NA | NA | 20.95930452 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 970.9377468 | 367.0593119 | NA | NA | 86.51670951 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_015 | guo_2023_exp_003_assay_008 | guo_2023_exp2_015_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | distance in region of contact | distance travelled in aggressive zone | NA | NA | fig4c | guo_2023_fig4c | NA | NA | NA | 18 | 718.7022832 | 88.9227981 | NA | NA | 20.95930452 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 1072.1142850 | 379.6290892 | NA | NA | 89.47943445 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_016 | guo_2023_exp_001_assay_009 | guo_2023_exp2_016_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4b | guo_2023_fig4b | NA | NA | NA | 18 | 295.2174154 | 51.7694062 | NA | NA | 12.20216606 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 301.5914375 | 52.1369996 | NA | NA | 12.28880866 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_017 | guo_2023_exp_002_assay_009 | guo_2023_exp2_017_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4b | guo_2023_fig4b | NA | NA | NA | 18 | 295.2174154 | 51.7694062 | NA | NA | 12.20216606 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 330.3398204 | 32.9302436 | NA | NA | 7.761732852 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_018 | guo_2023_exp_003_assay_009 | guo_2023_exp2_018_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4b | guo_2023_fig4b | NA | NA | NA | 18 | 295.2174154 | 51.7694062 | NA | NA | 12.20216606 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 373.8358539 | 35.7280077 | NA | NA | 8.421172178 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_001 | guo_2023_exp2_016 | guo_2023_exp_001_assay_010 | guo_2023_exp2_016_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 0.2 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4d | guo_2023_fig4d | NA | NA | NA | 18 | 401.5002235 | 46.0038347 | NA | NA | 10.84320782 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 404.2687021 | 27.4065398 | NA | NA | 6.459783385 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_002 | guo_2023_exp2_017 | guo_2023_exp_002_assay_010 | guo_2023_exp2_017_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 20 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4d | guo_2023_fig4d | NA | NA | NA | 18 | 401.5002235 | 46.0038347 | NA | NA | 10.84320782 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 454.2716458 | 116.7980733 | NA | NA | 27.52956989 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | SN | KM | The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin | 10.1016/j.envpol.2023.121461 | https://www.sciencedirect.com/science/article/pii/S0269749123004633?via%3Dihub | Environmental Pollution | guo_2023 | guo_2023_exp_003 | guo_2023_exp2_018 | guo_2023_exp_003_assay_010 | guo_2023_exp2_018_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | azoxystrobin | analytical | 131860-33-8 | in paper | B-methoxyacrylates | 200 | ug/L | 42 | days | DMSO | solvent_used | 27 | celsius | aggression | aggression | frequency in region of contact | frequency of entries into aggression zone | entry | NA | fig4d | guo_2023_fig4d | NA | NA | NA | 18 | 401.5002235 | 46.0038347 | NA | NA | 10.84320782 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | 18 | 506.6776000 | 68.1248300 | NA | NA | 15.87722473 | study reports mean and se | states N=3, 18 per treatment - I assume this is 18 for each concentration | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp2_001 | gusso_2020_exp_001_assay_001 | gusso_2020_exp2_001_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.125 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 111.4008331 | 61.6942041 | NA | NA | 16.4884696 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 97.3645968 | 67.1674566 | NA | NA | 17.95125786 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp2_002 | gusso_2020_exp_002_assay_001 | gusso_2020_exp2_002_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.675 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 111.4008331 | 61.6942041 | NA | NA | 16.4884696 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 115.4811997 | 55.9483675 | NA | NA | 14.95283019 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp2_003 | gusso_2020_exp_003_assay_001 | gusso_2020_exp2_003_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 1.75 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 111.4008331 | 61.6942041 | NA | NA | 16.4884696 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 89.6508764 | 68.6872598 | NA | NA | 18.35744235 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp2_001 | gusso_2020_exp_001_assay_002 | gusso_2020_exp2_001_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.125 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 85.2610740 | 53.8304483 | NA | NA | 14.38679245 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 97.3645968 | 67.1674566 | NA | NA | 17.95125786 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp2_002 | gusso_2020_exp_002_assay_002 | gusso_2020_exp2_002_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.675 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 85.2610740 | 53.8304483 | NA | NA | 14.38679245 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 115.4811997 | 55.9483675 | NA | NA | 14.95283019 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp2_003 | gusso_2020_exp_003_assay_002 | gusso_2020_exp2_003_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 1.75 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | aggression | aggression | total aggressive behaviours towards mirror | frequency of aggressive behaviour | count | NA | fig3a | gusso_2020_fig3a | NA | NA | NA | 14 | 85.2610740 | 53.8304483 | NA | NA | 14.38679245 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 14 | 89.6508764 | 68.6872598 | NA | NA | 18.35744235 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp2_004 | gusso_2020_exp_001_assay_003 | gusso_2020_exp2_004_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.125 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 217.1531516 | 83.6582537 | NA | NA | 23.20262487 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp2_005 | gusso_2020_exp_002_assay_003 | gusso_2020_exp2_005_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.675 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 202.4163493 | 73.4836012 | NA | NA | 20.38068401 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp2_006 | gusso_2020_exp_003_assay_003 | gusso_2020_exp2_006_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 1.75 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 233.7712478 | 46.3511946 | NA | NA | 12.85550837 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp2_004 | gusso_2020_exp_001_assay_004 | gusso_2020_exp2_004_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.125 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 217.1531516 | 83.6582537 | NA | NA | 23.20262487 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp2_005 | gusso_2020_exp_002_assay_004 | gusso_2020_exp2_005_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 0.675 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 202.4163493 | 73.4836012 | NA | NA | 20.38068401 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| NA | NA | YY | KM | Pyriproxyfen Exposure Impairs Cognitive Parameters and Alters Cortisol Levels in Zebrafish | 10.3389/fnbeh.2020.00103 | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.00103/full | Frontiers in Behavioral Neuroscience | gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp2_006 | gusso_2020_exp_003_assay_004 | gusso_2020_exp2_006_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | pyriproxyfen | not reported | 95737- 68-1 | in paper | phenoxy | 1.75 | mg/L | 96 | hours | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent in the area closest to the stimulus aquarium | time spent in social zone | zone | NA | fig3b | gusso_2020_fig3b | NA | NA | NA | 13 | 221.2292884 | 59.9173979 | NA | NA | 16.61809619 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | 13 | 233.7712478 | 46.3511946 | NA | NA | 12.85550837 | study reports mean and se | sample size provided as a range so selected the lowest value | NA | NA | NA | NA |
| used species median of shoal | NA | YY | KM | Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish | 10.1016/j.ntt.2019.106853 | https://www.sciencedirect.com/science/article/pii/S0892036219301539?via%3Dihub | Neurotoxicology and Teratology | hawkey_2020 | hawkey_2020_exp_001 | hawkey_2020_exp2_001 | hawkey_2020_exp_001_assay_001 | hawkey_2020_exp2_001_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | DDT | not reported | 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT | organochlorine | 10 | nm | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | total distance moved | group movement | NA | NA | fig3b | hawkey_2020_fig3b | 18.000000 | 12.000000 | 36 | 36 | 2013.6537020 | 535.6481481 | 309.2566025 | 535.6481482 | 89.27469136 | study reports mean and se | exact sample size provided | 17.500000 | 11.666667 | 35 | 35 | 1494.9636350 | 687.3399572 | 89.2746914 | 116.1816578 | 116.1816578 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | YY | KM | Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish | 10.1016/j.ntt.2019.106853 | https://www.sciencedirect.com/science/article/pii/S0892036219301539?via%3Dihub | Neurotoxicology and Teratology | hawkey_2020 | hawkey_2020_exp_002 | hawkey_2020_exp2_002 | hawkey_2020_exp_002_assay_001 | hawkey_2020_exp2_002_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | DDT | not reported | 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT | organochlorine | 30 | nm | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | total distance moved | group movement | NA | NA | fig3b | hawkey_2020_fig3b | 18.000000 | 12.000000 | 36 | 36 | 2013.6537020 | 535.6481481 | 309.2566025 | 535.6481482 | 89.27469136 | study reports mean and se | exact sample size provided | 17.500000 | 11.666667 | 35 | 35 | 1741.4132600 | 571.8485849 | 89.2746914 | 96.6600529 | 96.66005291 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | YY | KM | Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish | 10.1016/j.ntt.2019.106853 | https://www.sciencedirect.com/science/article/pii/S0892036219301539?via%3Dihub | Neurotoxicology and Teratology | hawkey_2020 | hawkey_2020_exp_003 | hawkey_2020_exp2_003 | hawkey_2020_exp_003_assay_001 | hawkey_2020_exp2_003_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.3 | um | 2 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig5b | hawkey_2020_fig5b | 11.000000 | 7.333333 | 22 | 22 | 1.6812550 | 4.6226932 | 2.6689132 | 4.6226932 | 0.985561497 | study reports mean and se | exact sample size provided | 9.000000 | 6.000000 | 18 | 18 | 3.4988493 | 3.8752855 | 0.9855615 | 0.9134135 | 0.913413547 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | YY | KM | Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish | 10.1016/j.ntt.2019.106853 | https://www.sciencedirect.com/science/article/pii/S0892036219301539?via%3Dihub | Neurotoxicology and Teratology | hawkey_2020 | hawkey_2020_exp_004 | hawkey_2020_exp2_004 | hawkey_2020_exp_004_assay_001 | hawkey_2020_exp2_004_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 1 | um | 2 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig5b | hawkey_2020_fig5b | 11.000000 | 7.333333 | 22 | 22 | 1.6812550 | 4.6226932 | 2.6689132 | 4.6226932 | 0.985561497 | study reports mean and se | exact sample size provided | 11.000000 | 7.333333 | 22 | 22 | 5.1874444 | 4.5148387 | 0.9855615 | 0.9625668 | 0.962566845 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | YY | KM | Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish | 10.1016/j.ntt.2019.106853 | https://www.sciencedirect.com/science/article/pii/S0892036219301539?via%3Dihub | Neurotoxicology and Teratology | hawkey_2020 | hawkey_2020_exp_005 | hawkey_2020_exp2_005 | hawkey_2020_exp_005_assay_001 | hawkey_2020_exp2_005_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 3 | um | 2 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig5b | hawkey_2020_fig5b | 11.000000 | 7.333333 | 22 | 22 | 1.6812550 | 4.6226932 | 2.6689132 | 4.6226932 | 0.985561497 | study reports mean and se | exact sample size provided | 10.000000 | 6.666667 | 20 | 20 | 7.2280091 | 6.2089749 | 0.9855615 | 1.3883690 | 1.388368984 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_001 | hawkey_2021_exp2_001 | hawkey_2021_exp_001_assay_001 | hawkey_2021_exp2_001_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | distance | group movement | NA | NA | fig3a | hawkey_2021_fig3a | 23.000000 | 15.333333 | 46 | 46 | 184.4213398 | 76.0345316 | 48.9472505 | 84.7791248 | 12.5 | study reports mean and se | exact sample size provided | 23.500000 | 15.666667 | 47 | 47 | 167.6488638 | 61.7590761 | 41.3195012 | 71.5674754 | 10.43918919 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_002 | hawkey_2021_exp2_002 | hawkey_2021_exp_002_assay_001 | hawkey_2021_exp2_002_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | DDT | not reported | 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT; https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | distance | group movement | NA | NA | fig3a | hawkey_2021_fig3a | 23.000000 | 15.333333 | 46 | 46 | 184.4213398 | 76.0345316 | 48.9472505 | 84.7791248 | 12.5 | study reports mean and se | exact sample size provided | 21.000000 | 14.000000 | 42 | 42 | 191.4803442 | 87.2189923 | 52.2567961 | 90.5114259 | 13.96621622 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_003 | hawkey_2021_exp2_003 | hawkey_2021_exp_003_assay_001 | hawkey_2021_exp2_003_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos ; DDT | not reported | 2921-88-2 ; 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate and organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | distance | group movement | NA | NA | fig3a | hawkey_2021_fig3a | 23.000000 | 15.333333 | 46 | 46 | 184.4213398 | 76.0345316 | 48.9472505 | 84.7791248 | 12.5 | study reports mean and se | exact sample size provided | 16.000000 | 10.666667 | 32 | 32 | 226.6114671 | 68.5836312 | 46.7058112 | 80.8968380 | 14.30067568 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_001 | hawkey_2021_exp2_004 | hawkey_2021_exp_001_assay_002 | hawkey_2021_exp2_004_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 23.000000 | 15.333333 | 46 | 46 | 4.1697558 | 6.3808160 | 3.6839659 | 6.3808160 | 0.9408 | study reports mean and se | exact sample size provided | 23.500000 | 15.666667 | 47 | 47 | 6.4433558 | 7.7551165 | 4.4774186 | 7.7551165 | 1.1312 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_002 | hawkey_2021_exp2_005 | hawkey_2021_exp_002_assay_002 | hawkey_2021_exp2_005_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | DDT | not reported | 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT | organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 23.000000 | 15.333333 | 46 | 46 | 4.1697558 | 6.3808160 | 3.6839659 | 6.3808160 | 0.9408 | study reports mean and se | exact sample size provided | 21.000000 | 14.000000 | 42 | 42 | 6.7793558 | 8.0568568 | 4.6516285 | 8.0568568 | 1.2432 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_003 | hawkey_2021_exp2_006 | hawkey_2021_exp_003_assay_002 | hawkey_2021_exp2_006_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos ; DDT | not reported | 2921-88-2 ; 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT; https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate and organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 23.000000 | 15.333333 | 46 | 46 | 4.1697558 | 6.3808160 | 3.6839659 | 6.3808160 | 0.9408 | study reports mean and se | exact sample size provided | 16.000000 | 10.666667 | 32 | 32 | 2.3441558 | 9.1233745 | 5.2673827 | 9.1233745 | 1.6128 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_004 | hawkey_2021_exp2_007 | hawkey_2021_exp_004_assay_001 | hawkey_2021_exp2_007_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos | not reported | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 18.500000 | 12.333333 | 37 | 37 | 5.1429639 | 8.2206508 | 4.7461950 | 8.2206508 | 1.351466667 | study reports mean and se | exact sample size provided | 17.500000 | 11.666667 | 35 | 35 | 7.3793195 | 7.7098352 | 4.4512754 | 7.7098352 | 1.3032 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_005 | hawkey_2021_exp2_008 | hawkey_2021_exp_005_assay_001 | hawkey_2021_exp2_008_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | DDT | not reported | 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT | organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 18.500000 | 12.333333 | 37 | 37 | 5.1429639 | 8.2206508 | 4.7461950 | 8.2206508 | 1.351466667 | study reports mean and se | exact sample size provided | 19.500000 | 13.000000 | 39 | 39 | 0.9437639 | 10.5498833 | 6.0909780 | 10.5498833 | 1.689333333 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| used species median of shoal | NA | NA | KM | Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact? | 10.1016/j.ntt.2021.106985 | https://www.sciencedirect.com/science/article/pii/S0892036221000398 | Neurotoxicology and Teratology | hawkey_2021 | hawkey_2021_exp_006 | hawkey_2021_exp2_009 | hawkey_2021_exp_006_assay_001 | hawkey_2021_exp2_009_assay2_001 | zebrafish | Danio rerio | labratory stock from wild population | not_wild | mixed | chlorpyrifos ; DDT | not reported | 2921-88-2 ; 50-29-3 | https://commonchemistry.cas.org/detail?cas_rn=50-29-3&search=DDT; https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate and organochlorine | NA | NA | 5 | weeks | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | change in position | group movement | NA | NA | fig3b | hawkey_2021_fig3b | 18.500000 | 12.333333 | 37 | 37 | 5.1429639 | 8.2206508 | 4.7461950 | 8.2206508 | 1.351466667 | study reports mean and se | exact sample size provided | 11.500000 | 7.666667 | 23 | 23 | 2.1986972 | 6.1727680 | 3.5638493 | 6.1727680 | 1.287111111 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_001 | hued_2011_exp_001_assay_001 | hued_2011_exp2_001_assay_001 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 7 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of persecutions | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 74.0000000 | 40.0000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 52.4000000 | 28.9000000 | NA | NA | not reported | study does not seem to report sample size | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_002 | hued_2011_exp_001_assay_002 | hued_2011_exp2_002_assay_001 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 28 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of persecutions | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 74.0000000 | 40.0000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 56.1600000 | 29.8000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_001 | hued_2011_exp_001_assay_003 | hued_2011_exp2_001_assay_002 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 7 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of copulation attempts | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 30.0000000 | 28.0000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 16.0000000 | 10.0000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_002 | hued_2011_exp_001_assay_004 | hued_2011_exp2_002_assay_002 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 28 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of copulation attempts | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 30.0000000 | 28.0000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 19.0000000 | 9.8000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_001 | hued_2011_exp_001_assay_005 | hued_2011_exp2_001_assay_003 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 7 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of copulations | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 3.3100000 | 1.5000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 1.4000000 | 0.8900000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_002 | hued_2011_exp_001_assay_006 | hued_2011_exp2_002_assay_003 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 28 | days | not reported | NA | 21 | celsius | sexual activity | courtship | number of copulations | frequency of courting events | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 3.3100000 | 1.5000000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 1.3000000 | 0.8100000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_001 | hued_2011_exp_001_assay_007 | hued_2011_exp2_001_assay_004 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 7 | days | not reported | NA | 21 | celsius | sexual activity | courtship | mating success | frequency of courting success | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 0.1700000 | 0.0300000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 0.1300000 | 0.0700000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Exposure to a commercial glyphosate formulation (Roundup<ae>) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). | 10.1007/s00244-011-9686-7 | https://link.springer.com/article/10.1007/s00244-011-9686-7#article-info | Archives of Environmental Contamination and Toxicology | hued_2011 | hued_2011_exp_001 | hued_2011_exp2_002 | hued_2011_exp_001_assay_008 | hued_2011_exp2_002_assay_004 | killifish | Jenynsia multidentata | wild collected | wild | male | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=ROUNDUP | organophosphate | 0.5 | mg/L | 28 | days | not reported | NA | 21 | celsius | sexual activity | courtship | mating success | frequency of courting success | count | NA | table2 | hued_2011_table2 | NA | NA | NA | 9 | 0.1700000 | 0.0300000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | 9 | 0.1100000 | 0.0700000 | NA | NA | not reported | study does not seem to report sample size | sample size is not provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4632 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_001 | hussian_2020_exp_001_assay_001 | hussian_2020_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | aggression | aggression | mirror biting time | frequency of aggressive behaviour | count | NA | fig6a | hussian_2020_fig6a | NA | NA | NA | 30 | 35.9972400 | 92.5622300 | NA | NA | 16.89947 | study reports mean and se | exact sample size provided | NA | NA | NA | NA | 18.1328600 | 196.3489900 | NA | NA | 35.84826 | study reports mean and se | sample size is not provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4633 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_002 | hussian_2020_exp_002_assay_001 | hussian_2020_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | aggression | aggression | mirror biting time | frequency of aggressive behaviour | count | NA | fig6a | hussian_2020_fig6a | NA | NA | NA | 30 | 35.9972400 | 92.5622300 | NA | NA | 16.89947 | study reports mean and se | exact sample size provided | NA | NA | NA | NA | 16.0956800 | 96.7800100 | NA | NA | 17.66953 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4634 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_001 | hussian_2020_exp_001_assay_002 | hussian_2020_exp2_001_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | aggression | aggression | duration of stay on mirror side | time spent in aggression zone | zone | NA | fig6f | hussian_2020_fig6f | NA | NA | NA | 30 | 7.6879031 | 54.6897674 | NA | NA | 9.984939759 | study reports mean and se | exact sample size provided | NA | NA | NA | NA | 1.4853408 | 64.7258484 | NA | NA | 11.81726908 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_002 | hussian_2020_exp_002_assay_002 | hussian_2020_exp2_002_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | aggression | aggression | duration of stay on mirror side | time spent in aggression zone | zone | NA | fig6f | hussian_2020_fig6f | NA | NA | NA | 30 | 7.6879031 | 54.6897674 | NA | NA | 9.984939759 | study reports mean and se | exact sample size provided | NA | NA | NA | NA | 1.4488098 | 28.3897360 | NA | NA | 5.183232932 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_003 | hussian_2020_exp_001_assay_003 | hussian_2020_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | interaction time percentage | time spent in social zone | zone | NA | fig8a | hussian_2020_fig8a | NA | NA | NA | 30 | 81.5410522 | 61.7080349 | NA | NA | 11.26629423 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 69.9260687 | 90.4902433 | NA | NA | 16.5211825 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_004 | hussian_2020_exp_002_assay_003 | hussian_2020_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | interaction time percentage | time spent in social zone | zone | NA | fig8a | hussian_2020_fig8a | NA | NA | NA | 30 | 81.5410522 | 61.7080349 | NA | NA | 11.26629423 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 60.9047814 | 188.3561267 | NA | NA | 34.38896648 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_003 | hussian_2020_exp_001_assay_004 | hussian_2020_exp2_003_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | longest duration of stay in seperator side | time spent in social zone | zone | NA | fig8b | hussian_2020_fig8b | NA | NA | NA | 30 | 13.1883201 | 100.5626276 | NA | NA | 18.36013986 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 12.2685210 | 103.4161472 | NA | NA | 18.88111888 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_004 | hussian_2020_exp_002_assay_004 | hussian_2020_exp2_004_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | longest duration of stay in seperator side | time spent in social zone | zone | NA | fig8b | hussian_2020_fig8b | NA | NA | NA | 30 | 13.1883201 | 100.5626276 | NA | NA | 18.36013986 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 8.9571015 | 69.3526558 | NA | NA | 12.66200466 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_003 | hussian_2020_exp_001_assay_006 | hussian_2020_exp2_003_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | average distance to seperator | distance from social zone | zone | change | fig8c | hussian_2020_fig8c | NA | NA | NA | 30 | 2.2370159 | 8.1965795 | NA | NA | 1.496483826 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 3.2841125 | 8.7789680 | NA | NA | 1.60281294 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_004 | hussian_2020_exp_002_assay_006 | hussian_2020_exp2_004_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | social interaction | sociality | average distance to seperator | distance from social zone | zone | change | fig8c | hussian_2020_fig8c | NA | NA | NA | 30 | 2.2370159 | 8.1965795 | NA | NA | 1.496483826 | study reports mean and se | exact sample size provided | NA | NA | NA | 30 | 3.6411234 | 5.5326911 | NA | NA | 1.010126582 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_003 | hussian_2020_exp_001_assay_007 | hussian_2020_exp2_003_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average speed | group movement | NA | NA | fig9a | hussian_2020_fig9a | 15.000000 | 10.000000 | 30 | 30 | 4.2971430 | 5.1144954 | 2.9528553 | 5.1144954 | 0.933774834 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 2.7982062 | 4.6908266 | 2.7082500 | 4.6908266 | 0.856423841 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_004 | hussian_2020_exp_002_assay_007 | hussian_2020_exp2_004_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average speed | group movement | NA | NA | fig9a | hussian_2020_fig9a | 15.000000 | 10.000000 | 30 | 30 | 4.2971430 | 5.1144954 | 2.9528553 | 5.1144954 | 0.933774834 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 2.8712296 | 2.4908681 | 1.4381034 | 2.4908681 | 0.454768212 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_005 | hussian_2020_exp_001_assay_008 | hussian_2020_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | time in top | group movement | NA | NA | fig9b | hussian_2020_fig9b | 15.000000 | 10.000000 | 30 | 30 | 33.5594914 | 62.1723871 | 35.8952444 | 62.1723871 | 11.35107296 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 7.0652319 | 93.0282081 | 53.7098610 | 93.0282081 | 16.98454936 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_006 | hussian_2020_exp_002_assay_008 | hussian_2020_exp2_006_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | time in top | group movement | NA | NA | fig9b | hussian_2020_fig9b | 15.000000 | 10.000000 | 30 | 30 | 33.5594914 | 62.1723871 | 35.8952444 | 62.1723871 | 11.35107296 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 26.2600044 | 91.1711231 | 52.6376724 | 91.1711231 | 16.64549356 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_005 | hussian_2020_exp_001_assay_009 | hussian_2020_exp2_005_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | distance between individuals | group arrangment | NA | change | fig9c | hussian_2020_fig9c | 15.000000 | 10.000000 | 30 | 30 | 4.8245342 | 4.5187111 | 2.6088791 | 4.5187111 | 0.825 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 4.9235806 | 3.5976724 | 2.0771171 | 3.5976724 | 0.656842105 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_006 | hussian_2020_exp_002_assay_009 | hussian_2020_exp2_006_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | distance between individuals | group arrangment | NA | change | fig9c | hussian_2020_fig9c | 15.000000 | 10.000000 | 30 | 30 | 4.8245342 | 4.5187111 | 2.6088791 | 4.5187111 | 0.825 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 4.6594483 | 5.1745368 | 2.9875202 | 5.1745368 | 0.944736842 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_005 | hussian_2020_exp_001_assay_010 | hussian_2020_exp2_005_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average shoal area | group arrangment | NA | change | fig9d | hussian_2020_fig9d | 15.000000 | 10.000000 | 30 | 30 | 4.1354624 | 4.5613382 | 2.6334898 | 4.5613382 | 0.832782609 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 4.5206079 | 1.1537895 | 0.6661407 | 1.1537895 | 0.210652174 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_006 | hussian_2020_exp_002_assay_010 | hussian_2020_exp2_006_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average shoal area | group arrangment | NA | change | fig9d | hussian_2020_fig9d | 15.000000 | 10.000000 | 30 | 30 | 4.1354624 | 4.5613382 | 2.6334898 | 4.5613382 | 0.832782609 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 4.6947100 | 1.7086562 | 0.9864931 | 1.7086562 | 0.311956522 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_005 | hussian_2020_exp_001_assay_011 | hussian_2020_exp2_005_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average nearest neighbor distance | group arrangment | NA | change | fig9e | hussian_2020_fig9e | 15.000000 | 10.000000 | 30 | 30 | 3.0067802 | 4.0631055 | 2.3458351 | 4.0631055 | 0.741818182 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 3.2103035 | 2.7722823 | 1.6005779 | 2.7722823 | 0.506147186 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_006 | hussian_2020_exp_002_assay_011 | hussian_2020_exp2_006_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average nearest neighbor distance | group arrangment | NA | change | fig9e | hussian_2020_fig9e | 15.000000 | 10.000000 | 30 | 30 | 3.0067802 | 4.0631055 | 2.3458351 | 4.0631055 | 0.741818182 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 3.0050537 | 4.0687961 | 2.3491205 | 4.0687961 | 0.742857143 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp2_005 | hussian_2020_exp_001_assay_012 | hussian_2020_exp2_005_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 100 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average farthest neighbor distance | group arrangment | NA | change | fig9f | hussian_2020_fig9f | 15.000000 | 10.000000 | 30 | 30 | 5.0477878 | 6.2732733 | 3.6218760 | 6.2732733 | 1.145337763 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 3.8698030 | 3.1553187 | 1.8217241 | 3.1553187 | 0.576079734 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish | 10.3390/ijerph17134632<a0> | https://www.mdpi.com/1660-4601/17/13/4635 | Environmental Research and Public Health | hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp2_006 | hussian_2020_exp_002_assay_012 | hussian_2020_exp2_006_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | paclobutrazol | not reported | 76738-62-0 | https://commonchemistry.cas.org/detail?cas_rn=76738-62-0&search=paclobutrazol | triazole | 1000 | ug/L | 14 | days | not reported | NA | 26.5 | celsius | shoaling | collective behaviour | average farthest neighbor distance | group arrangment | NA | change | fig9f | hussian_2020_fig9f | 15.000000 | 10.000000 | 30 | 30 | 5.0477878 | 6.2732733 | 3.6218760 | 6.2732733 | 1.145337763 | study reports mean and se | exact sample size provided | 15.000000 | 10.000000 | 30 | 30 | 4.6385098 | 6.0769909 | 3.5085523 | 6.0769909 | 1.109501661 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| does not report error type, so used a conservative estimate using SE | NA | NA | KM | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | 10.1016/j.aquatox.2023.106630 | https://www.sciencedirect.com/science/article/pii/S0166445X23002333?via%3Dihub | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | ibrahim_2023 | ibrahim_2023_exp_001 | ibrahim_2023_exp2_001 | ibrahim_2023_exp_001_assay_001 | ibrahim_2023_exp2_001_assay2_001 | Nile tilapia | Oreochromis niloticus | commercial supplier | not_wild | not reported | mancozeb | analytical | NA | NA | dithiocarbamate | 4 | mg/L | 96 | hours | not reported | NA | 23 | celsius | aggression | aggression | number of chases | frequency of aggressive behaviour | count | NA | table1 | ibrahim_2023_table1 | NA | NA | NA | 10 | -0.2000000 | 0.0316228 | NA | NA | 0.01 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 10 | 1.2000000 | 0.4110961 | NA | NA | 0.13 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| does not report error type, so used a conservative estimate using SE | NA | NA | KM | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | 10.1016/j.aquatox.2023.106630 | https://www.sciencedirect.com/science/article/pii/S0166445X23002333?via%3Dihub | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | ibrahim_2023 | ibrahim_2023_exp_002 | ibrahim_2023_exp2_002 | ibrahim_2023_exp_001_assay_002 | ibrahim_2023_exp2_002_assay2_001 | Nile tilapia | Oreochromis niloticus | commercial supplier | not_wild | not reported | mancozeb | analytical | NA | NA | dithiocarbamate | 8 | mg/L | 96 | hours | not reported | NA | 23 | celsius | aggression | aggression | number of chases | frequency of aggressive behaviour | count | NA | table1 | ibrahim_2023_table1 | NA | NA | NA | 10 | -0.2000000 | 0.0316228 | NA | NA | 0.01 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 10 | 1.6000000 | 0.2846050 | NA | NA | 0.09 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| does not report error type, so used a conservative estimate using SE | NA | NA | KM | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | 10.1016/j.aquatox.2023.106630 | https://www.sciencedirect.com/science/article/pii/S0166445X23002333?via%3Dihub | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | ibrahim_2023 | ibrahim_2023_exp_003 | ibrahim_2023_exp2_003 | ibrahim_2023_exp_001_assay_003 | ibrahim_2023_exp2_003_assay2_001 | Nile tilapia | Oreochromis niloticus | commercial supplier | not_wild | not reported | mancozeb | analytical | NA | NA | dithiocarbamate | 12 | mg/L | 96 | hours | not reported | NA | 23 | celsius | aggression | aggression | number of chases | frequency of aggressive behaviour | count | NA | table1 | ibrahim_2023_table1 | NA | NA | NA | 10 | -0.2000000 | 0.0316228 | NA | NA | 0.01 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 10 | 1.9000000 | 0.2213594 | NA | NA | 0.07 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| does not report error type, so used a conservative estimate using SE | NA | NA | KM | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | 10.1016/j.aquatox.2023.106630 | https://www.sciencedirect.com/science/article/pii/S0166445X23002333?via%3Dihub | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | ibrahim_2023 | ibrahim_2023_exp_004 | ibrahim_2023_exp2_004 | ibrahim_2023_exp_001_assay_004 | ibrahim_2023_exp2_004_assay2_001 | Nile tilapia | Oreochromis niloticus | commercial supplier | not_wild | not reported | mancozeb | analytical | NA | NA | dithiocarbamate | 16 | mg/L | 96 | hours | not reported | NA | 23 | celsius | aggression | aggression | number of chases | frequency of aggressive behaviour | count | NA | table1 | ibrahim_2023_table1 | NA | NA | NA | 10 | -0.2000000 | 0.0316228 | NA | NA | 0.01 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 10 | 1.9600000 | 0.3478505 | NA | NA | 0.11 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| does not report error type, so used a conservative estimate using SE | NA | NA | KM | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | 10.1016/j.aquatox.2023.106630 | https://www.sciencedirect.com/science/article/pii/S0166445X23002333?via%3Dihub | Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus) | ibrahim_2023 | ibrahim_2023_exp_005 | ibrahim_2023_exp2_005 | ibrahim_2023_exp_001_assay_005 | ibrahim_2023_exp2_005_assay2_001 | Nile tilapia | Oreochromis niloticus | commercial supplier | not_wild | not reported | mancozeb | analytical | NA | NA | dithiocarbamate | 20 | mg/L | 96 | hours | not reported | NA | 23 | celsius | aggression | aggression | number of chases | frequency of aggressive behaviour | count | NA | table1 | ibrahim_2023_table1 | NA | NA | NA | 10 | -0.2000000 | 0.0316228 | NA | NA | 0.01 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 10 | 2.1100000 | 0.4743416 | NA | NA | 0.15 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_001 | ilie_2021_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 1 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 140.5891426 | 112.8291361 | NA | NA | 29.13235767 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 102.8164520 | 66.1634655 | NA | NA | 17.08333333 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_002 | ilie_2021_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 2 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 127.9395662 | 132.1288567 | NA | NA | 34.11552412 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 145.3694823 | 85.4110191 | NA | NA | 22.0530303 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_003 | ilie_2021_exp2_001_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 3 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 128.7062072 | 102.4369788 | NA | NA | 26.4491142 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 133.2558459 | 97.4407401 | NA | NA | 25.15909091 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_004 | ilie_2021_exp2_001_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 4 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 98.4238880 | 59.3837558 | NA | NA | 15.33281983 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 167.7331186 | 34.8861909 | NA | NA | 9.007575758 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629103 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_005 | ilie_2021_exp2_001_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 5 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 154.7720009 | 65.3221314 | NA | NA | 16.86610181 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 136.0513004 | 39.6980793 | NA | NA | 10.25 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_006 | ilie_2021_exp2_001_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 6 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 150.5554755 | 65.3221314 | NA | NA | 16.86610181 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 72.0664520 | 117.8912658 | NA | NA | 30.43939394 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_007 | ilie_2021_exp2_001_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 7 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 153.2387189 | 56.4145680 | NA | NA | 14.56617884 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 153.4452398 | 80.5991307 | NA | NA | 20.81060606 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_008 | ilie_2021_exp2_001_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 8 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 141.9599901 | 67.4764101 | NA | NA | 17.42233417 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 92.8770580 | 61.3515771 | NA | NA | 15.84090909 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_009 | ilie_2021_exp2_001_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 9 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 126.2798894 | 79.6221639 | NA | NA | 20.55835432 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 151.8922095 | 141.9507078 | NA | NA | 36.65151515 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_010 | ilie_2021_exp2_001_assay2_010 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 10 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 121.7500825 | 101.2146152 | NA | NA | 26.13350126 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 90.0816035 | 93.8318238 | NA | NA | 24.22727273 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_011 | ilie_2021_exp2_001_assay2_011 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 11 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 157.2916442 | 26.9905640 | NA | NA | 6.968933669 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 135.4300883 | 111.8764053 | NA | NA | 28.88636364 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_012 | ilie_2021_exp2_001_assay2_012 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 12 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 143.0053302 | 94.4669742 | NA | NA | 24.39126784 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 142.2634217 | 42.1040235 | NA | NA | 10.87121212 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_013 | ilie_2021_exp2_001_assay2_013 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 13 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 101.8886215 | 66.1268819 | NA | NA | 17.07388749 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 76.4149368 | 111.8764053 | NA | NA | 28.88636364 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_014 | ilie_2021_exp2_001_assay2_014 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 14 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 133.2488231 | 47.2334871 | NA | NA | 12.19563392 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 96.2937247 | 98.6437122 | NA | NA | 25.46969697 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_015 | ilie_2021_exp2_001_assay2_015 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 15 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 103.2688888 | 28.7128377 | NA | NA | 7.413622827 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 133.8770580 | 73.3812981 | NA | NA | 18.9469697 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_016 | ilie_2021_exp2_001_assay2_016 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 16 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 116.0367948 | 73.3772520 | NA | NA | 18.945925 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 86.6649368 | 131.1239589 | NA | NA | 33.85606061 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_017 | ilie_2021_exp2_001_assay2_017 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 17 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 147.7506257 | 84.5433556 | NA | NA | 21.82900054 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 132.3240277 | 90.2229075 | NA | NA | 23.29545455 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_018 | ilie_2021_exp2_001_assay2_018 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 18 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 117.2723986 | 79.7578826 | NA | NA | 20.59339674 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 146.3013004 | 90.2229075 | NA | NA | 23.29545455 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_019 | ilie_2021_exp2_001_assay2_019 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 19 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 107.3875681 | 124.4222969 | NA | NA | 32.12569891 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 133.5664520 | 105.8615448 | NA | NA | 27.33333333 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_020 | ilie_2021_exp2_001_assay2_020 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 20 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 100.7976812 | 76.5675673 | NA | NA | 19.76966087 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 171.1497853 | 99.8466843 | NA | NA | 25.78030303 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | The Possible Role of<a0>Bifidobacterium longum<a0>BB536 and<a0>Lactobacillus rhamnosus<a0>HN001 on Locomotor Activity and Oxidative Stress in a Rotenone-Induced Zebrafish Model of Parkinson’s Disease | 10.1155/2021/9629102 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531778/ | Oxidative Medicine and Cellular Longevity | ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp2_001 | ilie_2021_exp_001_assay_021 | ilie_2021_exp2_001_assay2_021 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2 | ug/L | 21 | days | none | none | 26 | celsius | social interaction | sociality | time spent in the left arm | time spent in social zone | zone | NA | fig5 | ilie_2021_fig5 | NA | NA | NA | 15 | 118.0961344 | 55.8305178 | NA | NA | 14.41537772 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | 15 | 169.5967550 | 86.6139912 | NA | NA | 22.36363636 | study reports mean and se | exact sample size provided (section 2.4. Design Protocol) | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_001 | ilie_2022_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 1 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 24.1711521 | 6.1675584 | NA | NA | 2.758215962 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 54.3138300 | 18.2243696 | NA | NA | 8.150185874 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_002 | ilie_2022_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 4 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 14.5725605 | 13.0752238 | NA | NA | 5.84741784 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 37.1078821 | 47.2483657 | NA | NA | 21.13011152 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_003 | ilie_2022_exp2_001_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 8 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 10.3800723 | 5.1807490 | NA | NA | 2.316901408 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 25.9391089 | 11.4746031 | NA | NA | 5.131598513 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_004 | ilie_2022_exp2_001_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 12 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 20.7509643 | 15.7889495 | NA | NA | 7.061032864 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 8.1294434 | 11.8120914 | NA | NA | 5.282527881 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_005 | ilie_2022_exp2_001_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 16 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 10.1594150 | 11.8417121 | NA | NA | 5.295774648 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 12.5063951 | 13.8370214 | NA | NA | 6.188104089 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_006 | ilie_2022_exp2_001_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 20 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 14.9035465 | 6.6609631 | NA | NA | 2.978873239 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 11.4498895 | 14.8494864 | NA | NA | 6.640892193 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_007 | ilie_2022_exp2_001_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 24 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 17.2204479 | 8.3878794 | NA | NA | 3.751173709 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 9.7896665 | 8.7746965 | NA | NA | 3.924163569 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_008 | ilie_2022_exp2_001_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 28 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 18.4340629 | 14.0620331 | NA | NA | 6.288732394 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 3.7524918 | 3.7123716 | NA | NA | 1.660223048 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson<92>s Disease Chronically Exposed to Rotenone | 10.3390/brainsci12070898 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9313068/ | Brain Sciences | ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp2_001 | ilie_2022_exp_001_assay_009 | ilie_2022_exp2_001_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | not reported | rotenone | commercial | 83-79-4 | https://commonchemistry.cas.org/detail?cas_rn=83-79-4&search=rotenone | rotenones | 2.5 | ug/L | 32 | days | none | none | 26 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig4e treatment; fig4a control | ilie_2022_fig4e_treatment; fig4a_control | NA | NA | NA | 5 | 14.0209173 | 12.8285214 | NA | NA | 5.737089202 | study reports mean and se | exact sample size provided | NA | NA | NA | 5 | 3.6015624 | 3.0373949 | NA | NA | 1.358364312 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of a pyrethroid pesticide on endocrine responses to female odours and reproductive behaviour in male parr of brown trout (Salmo trutta L.) | 10.1016/j.aquatox.2006.10.011 | https://www.sciencedirect.com/science/article/pii/S0166445X06003870?via%3Dihub | Aquatic Toxicology | jaensson_2007 | jaensson_2007_exp_001 | jaensson_2007_exp2_001 | jaensson_2007_exp_001_assay_001 | jaensson_2007_exp2_001_assay2_001 | brown trout | Salmo trutta | wild collected | wild | male | cypermethrin | not reported | 52315-07-8 | https://commonchemistry.cas.org/detail?cas_rn=52315-07-8&search=cypermethrin | pyrethroid | 0.1 | ug/L | 4 | days | not reported | NA | 6 | celsius | courting | courtship | number of courting events per six minutes | frequency of courting events | count | NA | fig2a | jaensson_2007_fig2a | NA | NA | NA | 24 | 5.4455962 | 8.3404826 | NA | NA | 1.702493876 | study reports mean and sd | exact sample size provided | NA | NA | NA | 12 | 8.6996395 | 11.9034852 | NA | NA | 3.436240208 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of a pyrethroid pesticide on endocrine responses to female odours and reproductive behaviour in male parr of brown trout (Salmo trutta L.) | 10.1016/j.aquatox.2006.10.011 | https://www.sciencedirect.com/science/article/pii/S0166445X06003870?via%3Dihub | Aquatic Toxicology | jaensson_2007 | jaensson_2007_exp_002 | jaensson_2007_exp2_002 | jaensson_2007_exp_002_assay_001 | jaensson_2007_exp2_002_assay2_001 | brown trout | Salmo trutta | wild collected | wild | male | cypermethrin | not reported | 52315-07-8 | https://commonchemistry.cas.org/detail?cas_rn=52315-07-8&search=cypermethrin | pyrethroid | 0.1 | ug/L | 4 | days | not reported | NA | 6 | celsius | courting | courtship | time near female | time spent near potential mate | NA | NA | fig2b | jaensson_2007_fig2b | NA | NA | NA | 15 | 360.3483120 | 426.5316456 | NA | NA | 110.1299973 | study reports mean and sd | exact sample size provided | NA | NA | NA | 7 | 671.4445668 | 512.6708861 | NA | NA | 193.7713813 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of a pyrethroid pesticide on endocrine responses to female odours and reproductive behaviour in male parr of brown trout (Salmo trutta L.) | 10.1016/j.aquatox.2006.10.011 | https://www.sciencedirect.com/science/article/pii/S0166445X06003870?via%3Dihub | Aquatic Toxicology | jaensson_2007 | jaensson_2007_exp_003 | jaensson_2007_exp2_003 | jaensson_2007_exp_002_assay_002 | jaensson_2007_exp2_003_assay2_001 | brown trout | Salmo trutta | wild collected | wild | male | cypermethrin | not reported | 52315-07-8 | https://commonchemistry.cas.org/detail?cas_rn=52315-07-8&search=cypermethrin | pyrethroid | 1 | ug/L | 4 | days | not reported | NA | 6 | celsius | courting | courtship | time near female | time spent near potential mate | NA | NA | fig2b | jaensson_2007_fig2b | NA | NA | NA | 15 | 360.3483120 | 426.5316456 | NA | NA | 110.1299973 | study reports mean and sd | exact sample size provided | NA | NA | NA | 5 | 76.9169366 | 66.0509931 | NA | NA | 29.5389021 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| unclear on number of shoals but seems to be one | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_001 | khalil_2013_exp_001_assay_001 | khalil_2013_exp2_001_assay2_001 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | swimming speed | group movement | NA | NA | fig3a | khalil_2013_fig3a | 1.714286 | 1.000000 | 6 | 6 | 1.3847356 | 0.6346154 | 0.2590806 | 0.6346154 | 0.259080646 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 1.2924279 | 0.4846154 | 0.1978434 | 0.4846154 | 0.197843402 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_002 | khalil_2013_exp_001_assay_002 | khalil_2013_exp2_002_assay2_001 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | swimming speed | group movement | NA | NA | fig3a | khalil_2013_fig3a | 1.714286 | 1.000000 | 6 | 6 | 0.7270433 | 0.1384615 | 0.0565267 | 0.1384615 | 0.056526686 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 1.4424279 | 0.4961538 | 0.2025540 | 0.4961538 | 0.202553959 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_001 | khalil_2013_exp_001_assay_003 | khalil_2013_exp2_001_assay2_002 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig3c | khalil_2013_fig3c | 1.714286 | 1.000000 | 6 | 6 | 8.5929786 | 4.7407407 | 1.9353993 | 4.7407407 | 1.935399303 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 6.8522378 | 2.5925926 | 1.0584215 | 2.5925926 | 1.058421494 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_002 | khalil_2013_exp_001_assay_004 | khalil_2013_exp2_002_assay2_002 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig3c | khalil_2013_fig3c | 1.714286 | 1.000000 | 6 | 6 | 5.2966823 | 3.9259259 | 1.6027525 | 3.9259259 | 1.602752548 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 2.7040897 | 1.1481481 | 0.4687295 | 1.1481481 | 0.468729519 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_001 | khalil_2013_exp_001_assay_005 | khalil_2013_exp2_001_assay2_003 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | NA | NA | fig3d | khalil_2013_fig3d | 1.714286 | 1.000000 | 6 | 6 | 42.3950804 | 57.9710145 | 23.6665676 | 57.9710145 | 23.66656756 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 81.5255151 | 43.4782609 | 17.7499257 | 43.4782609 | 17.74992567 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_002 | khalil_2013_exp_001_assay_006 | khalil_2013_exp2_002_assay2_003 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | DTNB | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | NA | NA | fig3d | khalil_2013_fig3d | 1.714286 | 1.000000 | 6 | 6 | 31.1631963 | 8.3333333 | 3.4020691 | 8.3333333 | 3.402069087 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 43.1197180 | 14.1304348 | 5.7687258 | 14.1304348 | 5.768725844 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_001 | khalil_2013_exp_001_assay_007 | khalil_2013_exp2_001_assay2_004 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | DTNB | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig3g | khalil_2013_fig3g | 1.714286 | 1.000000 | 6 | 6 | 4.2084367 | 4.1089109 | 1.6774558 | 4.1089109 | 1.677455847 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 7.1292288 | 0.8910891 | 0.3637856 | 0.8910891 | 0.363785605 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_002 | khalil_2013_exp_001_assay_008 | khalil_2013_exp2_002_assay2_004 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | DTNB | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig3g | khalil_2013_fig3g | 1.714286 | 1.000000 | 6 | 6 | 9.2084367 | 2.2772277 | 0.9296743 | 2.2772277 | 0.929674325 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 10.1490308 | 0.8415842 | 0.3435753 | 0.8415842 | 0.343575294 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_001 | khalil_2013_exp_001_assay_009 | khalil_2013_exp2_001_assay2_005 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | DTNB | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig3h | khalil_2013_fig3h | 1.714286 | 1.000000 | 6 | 6 | 54.5151962 | 44.7368421 | 18.2637393 | 44.7368421 | 18.26373931 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 68.0490307 | 20.6766917 | 8.4412241 | 20.6766917 | 8.441224051 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Alterations in social behavior of Japanese medaka (Oryzias latipes) in response to sublethal chlorpyrifos exposure | 10.1016/j.chemosphere.2013.02.042 | https://www.sciencedirect.com/science/article/pii/S0045653513003500?via%3Dihub | Chemosphere | khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp2_002 | khalil_2013_exp_001_assay_010 | khalil_2013_exp2_002_assay2_005 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | DTNB | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig3h | khalil_2013_fig3h | 1.714286 | 1.000000 | 6 | 6 | 56.3948954 | 19.1729323 | 7.8273168 | 19.1729323 | 7.827316847 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | 1.714286 | 1.000000 | 6 | 6 | 57.8986548 | 7.1428571 | 2.9160592 | 7.1428571 | 2.916059218 | study reports mean and sd | states six fish were placed in recording glass aquarium for social behaviour (section 2.4. Subacute testing) | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_001 | khalil_2017_exp2_001_assay2_001 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1a | khalil_2017_fig1a | 1.600000 | 1.000000 | 4 | 4 | 25.1622508 | 6.5437788 | 3.2718894 | 6.5437788 | 3.271889401 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 21.6227979 | 5.9523810 | 5.9523810 | 11.9047619 | 5.952380952 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_002 | khalil_2017_exp2_001_assay2_002 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1a | khalil_2017_fig1a | 1.600000 | 1.000000 | 4 | 4 | 13.7336794 | 1.6589862 | 0.8294931 | 1.6589862 | 0.829493088 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 18.7974491 | 4.8387097 | 4.8387097 | 9.6774194 | 4.838709677 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_003 | khalil_2017_exp2_001_assay2_003 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 12 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1a | khalil_2017_fig1a | 1.600000 | 1.000000 | 4 | 4 | 12.8742828 | 3.1585253 | 1.5792627 | 3.1585253 | 1.579262673 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 4.4249237 | 0.3686636 | 0.3686636 | 0.7373272 | 0.368663594 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp2_002 | khalil_2017_exp_002_assay_001 | khalil_2017_exp2_002_assay2_001 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.12 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1a | khalil_2017_fig1a | 1.600000 | 1.000000 | 4 | 4 | 25.1622508 | 6.5437788 | 3.2718894 | 6.5437788 | 3.271889401 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 7.6507301 | 2.1198157 | 2.1198157 | 4.2396313 | 2.119815668 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_004 | khalil_2017_exp2_001_assay2_004 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1b | khalil_2017_fig1b | 1.600000 | 1.000000 | 4 | 4 | 2.6283093 | 0.9241877 | 0.4620939 | 0.9241877 | 0.462093863 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 2.6283093 | 0.9241877 | 0.4275572 | 0.8551143 | 0.42755716 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_005 | khalil_2017_exp2_001_assay2_005 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1b | khalil_2017_fig1b | 1.600000 | 1.000000 | 4 | 4 | 1.7179245 | 0.4049697 | 0.2024849 | 0.4049697 | 0.202484858 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 1.7179245 | 0.4049697 | 1.0384116 | 2.0768231 | 1.038411552 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_006 | khalil_2017_exp2_001_assay2_006 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 12 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1b | khalil_2017_fig1b | 1.600000 | 1.000000 | 4 | 4 | 1.8170988 | 0.4161252 | 0.2080626 | 0.4161252 | 0.208062575 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 1.8170988 | 0.4161252 | 0.0361011 | 0.0722022 | 0.036101083 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp2_002 | khalil_2017_exp_002_assay_002 | khalil_2017_exp2_002_assay2_002 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.12 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | schooling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1b | khalil_2017_fig1b | 1.600000 | 1.000000 | 4 | 4 | 2.6283093 | 0.9241877 | 0.4620939 | 0.9241877 | 0.462093863 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 2.6283093 | 0.9241877 | 0.0476534 | 0.0953069 | 0.04765343 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_007 | khalil_2017_exp2_001_assay2_007 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1c | khalil_2017_fig1c | 1.600000 | 1.000000 | 4 | 4 | 32.7539254 | 5.2864608 | 2.6432304 | 5.2864608 | 2.643230404 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 28.2736546 | 6.6555819 | 3.3277910 | 6.6555819 | 3.327790974 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_008 | khalil_2017_exp2_001_assay2_008 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1c | khalil_2017_fig1c | 1.600000 | 1.000000 | 4 | 4 | 20.1702236 | 2.2992874 | 1.1496437 | 2.2992874 | 1.149643705 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 20.8205371 | 6.1325416 | 3.0662708 | 6.1325416 | 3.066270784 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_009 | khalil_2017_exp2_001_assay2_009 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 12 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1c | khalil_2017_fig1c | 1.600000 | 1.000000 | 4 | 4 | 15.1612349 | 3.3583531 | 1.6791766 | 3.3583531 | 1.679176564 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 14.1766689 | 2.9878068 | 1.4939034 | 2.9878068 | 1.493903405 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp2_002 | khalil_2017_exp_002_assay_003 | khalil_2017_exp2_002_assay2_003 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.12 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | frequency | frequency of group behaviour | count | NA | fig1c | khalil_2017_fig1c | 1.600000 | 1.000000 | 4 | 4 | 32.7539254 | 5.2864608 | 2.6432304 | 5.2864608 | 2.643230404 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 13.0943802 | 4.5160728 | 2.2580364 | 4.5160728 | 2.258036421 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_010 | khalil_2017_exp2_001_assay2_010 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1d | khalil_2017_fig1d | 1.600000 | 1.000000 | 4 | 4 | 32.7539254 | 5.2864608 | 2.6432304 | 5.2864608 | 2.643230404 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 28.2736546 | 6.6555819 | 3.3277910 | 6.6555819 | 3.327790974 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_011 | khalil_2017_exp2_001_assay2_011 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 8 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1d | khalil_2017_fig1d | 1.600000 | 1.000000 | 4 | 4 | 20.1702236 | 2.2992874 | 1.1496437 | 2.2992874 | 1.149643705 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 20.8205371 | 6.1325416 | 3.0662708 | 6.1325416 | 3.066270784 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp2_001 | khalil_2017_exp_001_assay_012 | khalil_2017_exp2_001_assay2_012 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.012 | mg/L | 12 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1d | khalil_2017_fig1d | 1.600000 | 1.000000 | 4 | 4 | 15.1612349 | 3.3583531 | 1.6791766 | 3.3583531 | 1.679176564 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 14.1766689 | 2.9878068 | 1.4939034 | 2.9878068 | 1.493903405 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Comparison of social behavior responses of Japanese medaka (Oryzias latipes) to lethal and sublethal chlorpyrifos concentrations at different exposure times | 10.1016/j.ecoenv.2017.07.007 | https://www.sciencedirect.com/science/article/pii/S0147651317304219?via%3Dihub | Ecotoxicology and Environmental Safety | khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp2_002 | khalil_2017_exp_002_assay_004 | khalil_2017_exp2_002_assay2_004 | Japanese medaka | Oryzias latipes | laboratory stock from not specified source | not_wild | not reported | chlorpyrifos | analytical | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.12 | mg/L | 4 | days | ethanol | solvent_used | 25 | celsius | shoaling | collective behaviour | duration | duration of group behaviour | NA | NA | fig1d | khalil_2017_fig1d | 1.600000 | 1.000000 | 4 | 4 | 32.7539254 | 5.2864608 | 2.6432304 | 5.2864608 | 2.643230404 | study reports mean and sd | exact sample size provided | 1.600000 | 1.000000 | 4 | 4 | 13.0943802 | 4.5160728 | 2.2580364 | 4.5160728 | 2.258036421 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_001 | lei_2022_exp2_001 | lei_2022_exp_001_assay_001 | lei_2022_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-5 | in paper | pyrethroid | 30 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | social preference | sociality | proportion of time in near zone | time spent in social zone | zone | NA | fig1a | lei_2022_fig1a | NA | NA | NA | 16 | 67.7652167 | 5.6063447 | NA | NA | 1.401586177 | study reports boxplot | exact sample size provided | NA | NA | NA | 16 | 71.5867192 | 4.3421273 | NA | NA | 1.085531837 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_002 | lei_2022_exp2_002 | lei_2022_exp_002_assay_001 | lei_2022_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-5 | in paper | pyrethroid | 100 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | social preference | sociality | proportion of time in near zone | time spent in social zone | zone | NA | fig1a | lei_2022_fig1a | NA | NA | NA | 16 | 67.7652167 | 5.6063447 | NA | NA | 1.401586177 | study reports boxplot | exact sample size provided | NA | NA | NA | 16 | 71.7727601 | 4.0249352 | NA | NA | 1.006233793 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_003 | lei_2022_exp2_003 | lei_2022_exp_003_assay_001 | lei_2022_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-5 | in paper | pyrethroid | 333 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | social preference | sociality | proportion of time in near zone | time spent in social zone | zone | NA | fig1a | lei_2022_fig1a | NA | NA | NA | 16 | 67.7652167 | 5.6063447 | NA | NA | 1.401586177 | study reports boxplot | exact sample size provided | NA | NA | NA | 16 | 70.8589712 | 4.6576603 | NA | NA | 1.164415072 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_001 | lei_2022_exp2_004 | lei_2022_exp_001_assay_002 | lei_2022_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-6 | in paper | pyrethroid | 30 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | nearest neighbour distance | group arrangment | NA | change | fig2b | lei_2022_fig2b | 5.333330 | 3.000000 | 24 | 24 | 0.2164954 | 0.0320216 | 0.0359223 | 0.1016036 | 0.02073975 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.2413325 | 0.0395154 | 0.0432253 | 0.1222597 | 0.024956164 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_002 | lei_2022_exp2_005 | lei_2022_exp_002_assay_002 | lei_2022_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-7 | in paper | pyrethroid | 100 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | nearest neighbour distance | group arrangment | NA | change | fig2b | lei_2022_fig2b | 5.333330 | 3.000000 | 24 | 24 | 0.2164954 | 0.0320216 | 0.0359223 | 0.1016036 | 0.02073975 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.2036391 | 0.0185236 | 0.0198888 | 0.0562540 | 0.0114828 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_003 | lei_2022_exp2_006 | lei_2022_exp_003_assay_002 | lei_2022_exp2_006_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-8 | in paper | pyrethroid | 333 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | nearest neighbour distance | group arrangment | NA | change | fig2b | lei_2022_fig2b | 5.333330 | 3.000000 | 24 | 24 | 0.2164954 | 0.0320216 | 0.0359223 | 0.1016036 | 0.02073975 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.2257956 | 0.0230866 | 0.0241803 | 0.0683923 | 0.01396052 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_001 | lei_2022_exp2_004 | lei_2022_exp_001_assay_003 | lei_2022_exp2_004_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-9 | in paper | pyrethroid | 30 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | inter individual difference | group arrangment | NA | change | fig2c | lei_2022_fig2c | 5.333330 | 3.000000 | 24 | 24 | 0.1117781 | 0.0228166 | 0.1275315 | 0.3607136 | 0.073630358 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.1594948 | 0.0325567 | 0.1675055 | 0.4737772 | 0.096709364 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_002 | lei_2022_exp2_005 | lei_2022_exp_002_assay_003 | lei_2022_exp2_005_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-10 | in paper | pyrethroid | 100 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | inter individual difference | group arrangment | NA | change | fig2c | lei_2022_fig2c | 5.333330 | 3.000000 | 24 | 24 | 0.1117781 | 0.0228166 | 0.1275315 | 0.3607136 | 0.073630358 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.1511267 | 0.0308486 | 0.1643491 | 0.4648494 | 0.094886987 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | YY | KM | New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish | 10.1016/j.scitotenv.2022.153623 | https://www.sciencedirect.com/science/article/pii/S004896972200715X#:~:text=Taken%20together%2C%20deltamethrin%20exposure%20increased,social%20behaviors%20in%20adult%20zebrafish. | Science of The Total Environment | lei_2022 | lei_2022_exp_003 | lei_2022_exp2_006 | lei_2022_exp_003_assay_003 | lei_2022_exp2_006_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | deltamethrin | analytical | 52918-63-11 | in paper | pyrethroid | 333 | ng/L | 21 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | inter individual difference | group arrangment | NA | change | fig2c | lei_2022_fig2c | 5.333330 | 3.000000 | 24 | 24 | 0.1117781 | 0.0228166 | 0.1275315 | 0.3607136 | 0.073630358 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.500000 | 3.000000 | 24 | 24 | 0.1182762 | 0.0241430 | 0.1329097 | 0.3759255 | 0.076735472 | study reports boxplot | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | Swimming under Pressure: The Sub-Lethal Effects of a Pesticide on the Behaviour of Native and Non-Native Cypriniformes Fish | 10.3390/fishes8090462<a0> | https://www.mdpi.com/2410-3888/8/9/462 | Fishes | leite_2023 | leite_2023_exp_001 | leite_2023_exp2_001 | leite_2023_exp_001_assay_001 | leite_2023_exp2_001_assay2_001 | Iberian barbel | Luciobarbus bocagei | wild collected | wild | not reported | esfenvalerate | commercial | 66230-04-4 | https://commonchemistry.cas.org/detail?cas_rn=66230-04-4&search=esfenvalerate | pyrethroid | 1.2 | ug/L | 2 | hours | not reported | NA | not reported | not reported | shoaling | collective behaviour | cohesion | group arrangment | NA | change | in_text | leite_2023_in_text | 4.800000 | 3.000000 | 12 | 12 | 0.8130000 | 0.4535143 | 0.3585345 | 0.7170690 | 0.207 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.800000 | 3.000000 | 12 | 12 | 0.7050000 | 0.4666596 | 0.3689268 | 0.7378536 | 0.213 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | Swimming under Pressure: The Sub-Lethal Effects of a Pesticide on the Behaviour of Native and Non-Native Cypriniformes Fish | 10.3390/fishes8090462<a0> | https://www.mdpi.com/2410-3888/8/9/462 | Fishes | leite_2023 | leite_2023_exp_002 | leite_2023_exp2_002 | leite_2023_exp_002_assay_001 | leite_2023_exp2_002_assay2_001 | Iberian barbel | Luciobarbus bocagei | wild collected | wild | not reported | esfenvalerate | commercial | 66230-04-4 | https://commonchemistry.cas.org/detail?cas_rn=66230-04-4&search=esfenvalerate | pyrethroid | 2 | ug/L | 2 | hours | not reported | NA | not reported | not reported | shoaling | collective behaviour | cohesion | group arrangment | NA | change | in_text | leite_2023_in_text | 4.800000 | 3.000000 | 12 | 12 | 0.8130000 | 0.4535143 | 0.3585345 | 0.7170690 | 0.207 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.800000 | 3.000000 | 12 | 12 | 0.7110000 | 0.4622778 | 0.3654627 | 0.7309254 | 0.211 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | Swimming under Pressure: The Sub-Lethal Effects of a Pesticide on the Behaviour of Native and Non-Native Cypriniformes Fish | 10.3390/fishes8090462<a0> | https://www.mdpi.com/2410-3888/8/9/462 | Fishes | leite_2023 | leite_2023_exp_003 | leite_2023_exp2_003 | leite_2023_exp_003_assay_001 | leite_2023_exp2_003_assay2_001 | Bleak | Alburnus alburnus | wild collected | wild | not reported | esfenvalerate | commercial | 66230-04-4 | https://commonchemistry.cas.org/detail?cas_rn=66230-04-4&search=esfenvalerate | pyrethroid | 1.2 | ug/L | 2 | hours | not reported | NA | not reported | not reported | shoaling | collective behaviour | cohesion | group arrangment | NA | change | in_text | leite_2023_in_text | 4.800000 | 3.000000 | 12 | 12 | 0.3111064 | 0.2840000 | 0.2459512 | 0.4919024 | 0.142 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.800000 | 3.000000 | 12 | 12 | 0.9580000 | 0.3111064 | 0.2459512 | 0.4919024 | 0.142 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | Swimming under Pressure: The Sub-Lethal Effects of a Pesticide on the Behaviour of Native and Non-Native Cypriniformes Fish | 10.3390/fishes8090462<a0> | https://www.mdpi.com/2410-3888/8/9/462 | Fishes | leite_2023 | leite_2023_exp_004 | leite_2023_exp2_004 | leite_2023_exp_004_assay_001 | leite_2023_exp2_004_assay2_001 | Bleak | Alburnus alburnus | wild collected | wild | not reported | esfenvalerate | commercial | 66230-04-4 | https://commonchemistry.cas.org/detail?cas_rn=66230-04-4&search=esfenvalerate | pyrethroid | 2 | ug/L | 2 | hours | not reported | NA | not reported | not reported | shoaling | collective behaviour | cohesion | group arrangment | NA | change | in_text | leite_2023_in_text | 4.800000 | 3.000000 | 12 | 12 | 0.3111064 | 0.2840000 | 0.2459512 | 0.4919024 | 0.142 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 4.800000 | 3.000000 | 12 | 12 | 0.8960000 | 0.4031238 | 0.3186973 | 0.6373947 | 0.184 | study does not state error type used, so we assumed to be SE | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| states inter-fish distance as social and I would classify this as shoaling | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_001 | lin_2024_exp2_001 | lin_2024_exp_001_assay_001 | lin_2024_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | collective behaviour | inter-individual distance | group arrangment | NA | change | fig3d | lin_2024_fig3d | 3.200000 | 2.000000 | 8 | 2 | 26.8768721 | 0.6609307 | 0.6609307 | 1.3218615 | 0.467348605 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 2.500000 | 2.000000 | 8 | 2 | 22.7407249 | 0.6822511 | 0.6822511 | 1.3645022 | 0.482424367 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_002 | lin_2024_exp2_002 | lin_2024_exp_002_assay_001 | lin_2024_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | collective behaviour | inter-individual distance | group arrangment | NA | change | fig3d | lin_2024_fig3d | 3.200000 | 2.000000 | 8 | 2 | 24.5276826 | 0.5636322 | 0.5636322 | 1.1272645 | 0.39854817 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | 2.500000 | 2.000000 | 8 | 2 | 24.0457362 | 0.6616552 | 0.6616552 | 1.3233104 | 0.467860896 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_001 | lin_2024_exp2_003 | lin_2024_exp_001_assay_002 | lin_2024_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time in contact percentage | time spent with live fish | NA | NA | fig3c | lin_2024_fig3c | NA | NA | NA | 8 | 11.9623969 | 0.2969048 | NA | NA | 0.104971685 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | 8 | 11.7371588 | 0.2610714 | NA | NA | 0.092302689 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| NA | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_002 | lin_2024_exp2_004 | lin_2024_exp_002_assay_002 | lin_2024_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time in contact percentage | time spent with live fish | NA | NA | fig3c | lin_2024_fig3c | NA | NA | NA | 8 | 12.7914032 | 0.2208333 | NA | NA | 0.078076374 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | 8 | 11.6809270 | 0.3470238 | NA | NA | 0.122691444 | study reports mean and sd | calculated effective sample size from Rutkowska et al., 2014 (ICC assumed at 0.5) | NA | NA | NA | NA |
| stated mirror bites as social and I would classify as aggression | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_001 | lin_2024_exp2_005 | lin_2024_exp_001_assay_003 | lin_2024_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | female | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | aggression | mirror attack per minute | frequency of aggressive behaviour | count | NA | fig3e | lin_2024_fig3e | NA | NA | NA | 12 | 23.9643904 | 2.7620853 | NA | NA | 0.797345348 | study reports mean and sd | exact sample size provided | NA | NA | NA | 12 | 35.7255278 | 4.0985782 | NA | NA | 1.183157613 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | DDT and titanium dioxide nanoparticle coexposure induced neurobehavioral deficits in zebrafish | 10.1016/j.ntt.2024.107323 | https://www.sciencedirect.com/science/article/pii/S0892036224000059?via%3Dihub | NA | lin_2024 | lin_2024_exp_002 | lin_2024_exp2_006 | lin_2024_exp_002_assay_003 | lin_2024_exp2_006_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | male | DDT | analytical | P-029NB-250 | in paper | organochlorine | 5 | nm | 40 | days | DMSO | solvent_used | 28 | celsius | social interaction | aggression | mirror attack per minute | frequency of aggressive behaviour | count | NA | fig3e | lin_2024_fig3e | NA | NA | NA | 12 | 39.2094239 | 5.2042654 | NA | NA | 1.502342016 | study reports mean and sd | exact sample size provided | NA | NA | NA | 12 | 30.4108457 | 3.9687204 | NA | NA | 1.14567089 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Fenpropathrin causes alterations in locomotion and social behaviors in zebrafish (Danio rerio) | 10.1016/j.aquatox.2023.106756 | https://www.sciencedirect.com/science/article/pii/S0166445X23003582?via%3Dihub | Aquatic Toxicology | liu_2023 | liu_2023_exp_001 | liu_2023_exp2_001 | liu_2023_exp_001_assay_001 | liu_2023_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | fenpropathrin | not reported | 39,515<96>41<96>8 | in paper | pyrethroid | 500 | ppb | 72 | hours | DMSO | solvent_used | 28 | celsius | social preference | sociality | time in conspecific segment | time spent in social zone | zone | NA | fig3e | liu_2023_fig3e | NA | NA | NA | 10 | 408.9260085 | 418.2034951 | NA | NA | 132.247557 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 542.6038649 | 580.1835287 | NA | NA | 183.4701412 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Fenpropathrin causes alterations in locomotion and social behaviors in zebrafish (Danio rerio) | 10.1016/j.aquatox.2023.106756 | https://www.sciencedirect.com/science/article/pii/S0166445X23003582?via%3Dihub | Aquatic Toxicology | liu_2023 | liu_2023_exp_001 | liu_2023_exp2_002 | liu_2023_exp_001_assay_002 | liu_2023_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | fenpropathrin | not reported | 39,515<96>41<96>8 | in paper | pyrethroid | 500 | ppb | 72 | hours | DMSO | solvent_used | 28 | celsius | fighting | aggression | duration of fight control vs fenpropathrin | duration of aggressive behaviour | NA | NA | fig5c | liu_2023_fig5c | NA | NA | NA | 13 | 388.1335352 | 204.6781894 | NA | NA | 56.76751592 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 212.9291478 | 180.9413651 | NA | NA | 57.21868365 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Fenpropathrin causes alterations in locomotion and social behaviors in zebrafish (Danio rerio) | 10.1016/j.aquatox.2023.106756 | https://www.sciencedirect.com/science/article/pii/S0166445X23003582?via%3Dihub | Aquatic Toxicology | liu_2023 | liu_2023_exp_001 | liu_2023_exp2_002 | liu_2023_exp_001_assay_003 | liu_2023_exp2_002_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | fenpropathrin | not reported | 39,515<96>41<96>8 | in paper | pyrethroid | 500 | ppb | 72 | hours | DMSO | solvent_used | 28 | celsius | fighting | aggression | biting numbers | frequency of aggressive behaviour | count | NA | fig5f | liu_2023_fig5f | NA | NA | NA | 8 | 277.9932098 | 86.5616551 | NA | NA | 30.60416667 | study reports mean and se | exact sample size provided | NA | NA | NA | 10 | 219.9341103 | 80.6710207 | NA | NA | 25.51041667 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Integrate transcriptomic and metabolomic analysis reveals the underlying mechanisms of behavioral disorders in zebrafish (Danio rerio) induced by imidacloprid | 10.1016/j.scitotenv.2023.161541 | https://www.sciencedirect.com/science/article/pii/S0048969723001560?via%3Dihub | NA | liu_2023a | liu_2023a_exp_001 | liu_2023a_exp2_001 | liu_2023a_exp_001_assay_001 | liu_2023a_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | wild | not reported | imidacloprid | analytical | 138261-41-3 | https://commonchemistry.cas.org/detail?cas_rn=138261-41-3&search=imidacloprid | neonicotinoid | 1 | ug/L | 21 | days | not reported | NA | 26 | celsius | social interaction | sociality | time spent in conspecific zone | time spent in social zone | zone | NA | fig3e | liu_2023a_3e | NA | NA | NA | 14 | 258.3014343 | 31.0746713 | NA | NA | 8.305055233 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | 14 | 263.8601587 | 33.8996414 | NA | NA | 9.060060255 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | NA |
| NA | NA | NA | KM | Integrate transcriptomic and metabolomic analysis reveals the underlying mechanisms of behavioral disorders in zebrafish (Danio rerio) induced by imidacloprid | 10.1016/j.scitotenv.2023.161541 | https://www.sciencedirect.com/science/article/pii/S0048969723001560?via%3Dihub | NA | liu_2023a | liu_2023a_exp_002 | liu_2023a_exp2_002 | liu_2023a_exp_002_assay_001 | liu_2023a_exp2_002_assay2_001 | zebrafish | Danio rerio | commercial supplier | wild | not reported | imidacloprid | analytical | 138261-41-3 | https://commonchemistry.cas.org/detail?cas_rn=138261-41-3&search=imidacloprid | neonicotinoid | 10 | ug/L | 21 | days | not reported | NA | 26 | celsius | social interaction | sociality | time spent in conspecific zone | time spent in social zone | zone | NA | fig3e | liu_2023a_3e | NA | NA | NA | 14 | 258.3014343 | 31.0746713 | NA | NA | 8.305055233 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | 14 | 271.1182344 | 40.9620667 | NA | NA | 10.94757281 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | NA |
| NA | NA | NA | KM | Integrate transcriptomic and metabolomic analysis reveals the underlying mechanisms of behavioral disorders in zebrafish (Danio rerio) induced by imidacloprid | 10.1016/j.scitotenv.2023.161541 | https://www.sciencedirect.com/science/article/pii/S0048969723001560?via%3Dihub | NA | liu_2023a | liu_2023a_exp_003 | liu_2023a_exp2_003 | liu_2023a_exp_003_assay_001 | liu_2023a_exp2_003_assay2_001 | zebrafish | Danio rerio | commercial supplier | wild | not reported | imidacloprid | analytical | 138261-41-3 | https://commonchemistry.cas.org/detail?cas_rn=138261-41-3&search=imidacloprid | neonicotinoid | 100 | ug/L | 21 | days | not reported | NA | 26 | celsius | social interaction | sociality | time spent in conspecific zone | time spent in social zone | zone | NA | fig3e | liu_2023a_3e | NA | NA | NA | 14 | 258.3014343 | 31.0746713 | NA | NA | 8.305055233 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | 14 | 290.2281193 | 18.3623058 | NA | NA | 4.907532638 | caluclated difference in zone 2 and 1 | states range of sample sizes so selected lowest | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020306 | https://www.mdpi.com/2073-4441/15/2/306 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_001 | maclaren_2023_exp_001_assay_001 | maclaren_2023_exp2_001_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of female | time spent in courtship zone | zone | NA | fig3a | maclaren_2023_fig3a | NA | NA | NA | 20 | 362.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 370.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020307 | https://www.mdpi.com/2073-4441/15/2/307 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_002 | maclaren_2023_exp_002_assay_001 | maclaren_2023_exp2_002_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of female | time spent in courtship zone | zone | NA | fig3a | maclaren_2023_fig3a | NA | NA | NA | 20 | 362.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 344.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020308 | https://www.mdpi.com/2073-4441/15/2/308 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_003 | maclaren_2023_exp_001_assay_002 | maclaren_2023_exp2_003_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of male | time spent in courtship zone | zone | NA | fig3a | maclaren_2023_fig3a | NA | NA | NA | 20 | 480.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 276.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_004 | maclaren_2023_exp_002_assay_002 | maclaren_2023_exp2_004_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of male | time spent in courtship zone | zone | NA | fig3a | maclaren_2023_fig3a | NA | NA | NA | 20 | 480.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 356.0208435 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020306 | https://www.mdpi.com/2073-4441/15/2/306 | Water | maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp2_005 | maclaren_2023_exp_003_assay_001 | maclaren_2023_exp2_005_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of female | time spent in courtship zone | zone | NA | fig3b | maclaren_2023_fig3b | NA | NA | NA | 20 | 437.5210116 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 298.4081084 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020307 | https://www.mdpi.com/2073-4441/15/2/307 | Water | maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp2_006 | maclaren_2023_exp_004_assay_001 | maclaren_2023_exp2_006_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of female | time spent in courtship zone | zone | NA | fig3b | maclaren_2023_fig3b | NA | NA | NA | 20 | 437.5210116 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 304.4564955 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020308 | https://www.mdpi.com/2073-4441/15/2/308 | Water | maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp2_007 | maclaren_2023_exp_003_assay_002 | maclaren_2023_exp2_007_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of male | time spent in courtship zone | zone | NA | fig3b | maclaren_2023_fig3b | NA | NA | NA | 20 | 401.2306890 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 276.2306890 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp2_008 | maclaren_2023_exp_004_assay_002 | maclaren_2023_exp2_008_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time in preference zone of male | time spent in courtship zone | zone | NA | fig3b | maclaren_2023_fig3b | NA | NA | NA | 20 | 401.2306890 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 296.3919793 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp2_009 | maclaren_2023_exp_003_assay_003 | maclaren_2023_exp2_009_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | mean total time with dummy | time spent with simulated fish | NA | NA | fig4a | maclaren_2023_fig4a | NA | NA | NA | 20 | 842.5219795 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 644.1194236 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp2_010 | maclaren_2023_exp_004_assay_003 | maclaren_2023_exp2_010_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | mean total time with dummy | time spent with simulated fish | NA | NA | fig4a | maclaren_2023_fig4a | NA | NA | NA | 20 | 842.5219795 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 698.7520114 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp2_011 | maclaren_2023_exp_003_assay_004 | maclaren_2023_exp2_011_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | mean total time with dummy | time spent with simulated fish | NA | NA | fig4b | maclaren_2023_fig4b | NA | NA | NA | 20 | 733.5729629 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 503.5410141 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp2_012 | maclaren_2023_exp_004_assay_004 | maclaren_2023_exp2_012_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | mean total time with dummy | time spent with simulated fish | NA | NA | fig4b | maclaren_2023_fig4b | NA | NA | NA | 20 | 733.5729629 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 523.9882984 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_013 | maclaren_2023_exp_001_assay_003 | maclaren_2023_exp2_013_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (small and intermediate male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 144.6900000 | 67.4398102 | NA | NA | 15.08 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 187.0600000 | 155.8986594 | NA | NA | 34.86 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_014 | maclaren_2023_exp_002_assay_003 | maclaren_2023_exp2_014_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (small and intermediate male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 144.6900000 | 67.4398102 | NA | NA | 15.08 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 193.8000000 | 141.5878243 | NA | NA | 31.66 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_015 | maclaren_2023_exp_001_assay_004 | maclaren_2023_exp2_015_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (small and intermediate male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 246.3800000 | 80.0512336 | NA | NA | 17.9 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 206.7200000 | 158.9397118 | NA | NA | 35.54 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_016 | maclaren_2023_exp_002_assay_004 | maclaren_2023_exp2_016_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (small and intermediate male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 246.3800000 | 80.0512336 | NA | NA | 17.9 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 249.1000000 | 148.2960283 | NA | NA | 33.16 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_017 | maclaren_2023_exp_001_assay_005 | maclaren_2023_exp2_017_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (small and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 132.2300000 | 43.4244401 | NA | NA | 9.71 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 140.2800000 | 158.8502691 | NA | NA | 35.52 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_018 | maclaren_2023_exp_002_assay_005 | maclaren_2023_exp2_018_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (small and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 132.2300000 | 43.4244401 | NA | NA | 9.71 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 132.2500000 | 80.7667754 | NA | NA | 18.06 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_019 | maclaren_2023_exp_001_assay_006 | maclaren_2023_exp2_019_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (small and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 230.4600000 | 52.3239907 | NA | NA | 11.7 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 183.9400000 | 155.2278390 | NA | NA | 34.71 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_020 | maclaren_2023_exp_002_assay_006 | maclaren_2023_exp2_020_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (small and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 230.4600000 | 52.3239907 | NA | NA | 11.7 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 183.9400000 | 155.2278390 | NA | NA | 34.71 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_021 | maclaren_2023_exp_001_assay_007 | maclaren_2023_exp2_021_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (intermediate and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 143.0000000 | 53.7997955 | NA | NA | 12.03 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 143.3300000 | 125.8906271 | NA | NA | 28.15 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_022 | maclaren_2023_exp_002_assay_007 | maclaren_2023_exp2_022_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with smaller male (intermediate and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 143.0000000 | 53.7997955 | NA | NA | 12.03 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 178.0000000 | 126.5614475 | NA | NA | 28.3 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp2_023 | maclaren_2023_exp_001_assay_008 | maclaren_2023_exp2_023_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (intermediate and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 240.9200000 | 65.6956772 | NA | NA | 14.69 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 143.3300000 | 125.8906271 | NA | NA | 28.15 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp2_024 | maclaren_2023_exp_002_assay_008 | maclaren_2023_exp2_024_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | female | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | time with larger male (intermeditate and large male present) | time spent near potential mate | NA | NA | table1 | maclaren_2023_table1 | NA | NA | NA | 20 | 240.9200000 | 65.6956772 | NA | NA | 14.69 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 20 | 178.0000000 | 126.5614475 | NA | NA | 28.3 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp2_025 | maclaren_2023_exp_003_assay_005 | maclaren_2023_exp2_025_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 1 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | aggression | aggression | mean time in mirror zone | time spent in aggression zone | zone | NA | fig6 | maclaren_2023_fig6 | NA | NA | NA | 20 | 405.4809630 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 127.7465880 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Waterborne Atrazine Exposure Affects Behavior in Poecilia latipinna | 10.3390/w15020309 | https://www.mdpi.com/2073-4441/15/2/309 | Water | maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp2_026 | maclaren_2023_exp_004_assay_005 | maclaren_2023_exp2_026_assay2_001 | sailfin mollie | Poecilia latipinna | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | in paper | triazine | 15 | ppb | 12 | weeks | DMSO | solvent_used | 25 | celsius | aggression | aggression | mean time in mirror zone | time spent in aggression zone | zone | NA | fig6 | maclaren_2023_fig6 | NA | NA | NA | 20 | 405.4809630 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | 20 | 199.2309630 | NA | NA | NA | NA | study does not report error | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of the fungicide carbendazim on the behaviour of the zebrafish Danio rerio (Cypriniformes, Cyprinidae) | 10.1007/s10211-024-00438-8 | https://link.springer.com/article/10.1007/s10211-024-00438-8#:~:text=The%20results%20indicated%20that%20the,the%20bottom%20to%20the%20surface). | Acta Ethologica | oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp2_001 | oliveira_2024_exp_001_assay_001 | oliveira_2024_exp2_001_assay2_001 | zebrafish | Danio rerio | not reported | NA | mixed | carbendazim | not reported | 10605-21-7 | https://commonchemistry.cas.org/detail?cas_rn=10605-21-7&search=carbendazim | carbamate | 120 | ug/L | 7 | days | DMSO | solvent_used | 26 | celsius | aggression | aggression | mean number of recordings | frequency of aggressive behaviour | count | NA | fig2a | oliveira_2024_fig2a | NA | NA | NA | 22 | 18.7992279 | 14.4762578 | NA | NA | 3.08634853 | study reports boxplot | exact sample size provided | NA | NA | NA | 21 | 14.4543493 | 9.0628231 | NA | NA | 1.977670134 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of the fungicide carbendazim on the behaviour of the zebrafish Danio rerio (Cypriniformes, Cyprinidae) | 10.1007/s10211-024-00438-8 | https://link.springer.com/article/10.1007/s10211-024-00438-8#:~:text=The%20results%20indicated%20that%20the,the%20bottom%20to%20the%20surface). | Acta Ethologica | oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp2_001 | oliveira_2024_exp_001_assay_002 | oliveira_2024_exp2_001_assay2_002 | zebrafish | Danio rerio | not reported | NA | mixed | carbendazim | not reported | 10605-21-7 | https://commonchemistry.cas.org/detail?cas_rn=10605-21-7&search=carbendazim | carbamate | 120 | ug/L | 14 | days | DMSO | solvent_used | 26 | celsius | aggression | aggression | mean number of recordings | frequency of aggressive behaviour | count | NA | fig2a | oliveira_2024_fig2a | NA | NA | NA | 23 | 18.0526140 | 9.8309178 | NA | NA | 2.04988807 | study reports boxplot | exact sample size provided | NA | NA | NA | 21 | 15.4394650 | 9.4246408 | NA | NA | 2.056625235 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of the fungicide carbendazim on the behaviour of the zebrafish Danio rerio (Cypriniformes, Cyprinidae) | 10.1007/s10211-024-00438-8 | https://link.springer.com/article/10.1007/s10211-024-00438-8#:~:text=The%20results%20indicated%20that%20the,the%20bottom%20to%20the%20surface). | Acta Ethologica | oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp2_001 | oliveira_2024_exp_001_assay_003 | oliveira_2024_exp2_001_assay2_003 | zebrafish | Danio rerio | not reported | NA | mixed | carbendazim | not reported | 10605-21-7 | https://commonchemistry.cas.org/detail?cas_rn=10605-21-7&search=carbendazim | carbamate | 120 | ug/L | 21 | days | DMSO | solvent_used | 26 | celsius | aggression | aggression | mean number of recordings | frequency of aggressive behaviour | count | NA | fig2a | oliveira_2024_fig2a | NA | NA | NA | 22 | 8.3777409 | 4.4756635 | NA | NA | 0.954214663 | study reports boxplot | exact sample size provided | NA | NA | NA | 22 | 5.2668493 | 1.9110062 | NA | NA | 0.407427892 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of the fungicide carbendazim on the behaviour of the zebrafish Danio rerio (Cypriniformes, Cyprinidae) | 10.1007/s10211-024-00438-8 | https://link.springer.com/article/10.1007/s10211-024-00438-8#:~:text=The%20results%20indicated%20that%20the,the%20bottom%20to%20the%20surface). | Acta Ethologica | oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp2_001 | oliveira_2024_exp_001_assay_004 | oliveira_2024_exp2_001_assay2_004 | zebrafish | Danio rerio | not reported | NA | mixed | carbendazim | not reported | 10605-21-7 | https://commonchemistry.cas.org/detail?cas_rn=10605-21-7&search=carbendazim | carbamate | 120 | ug/L | 28 | days | DMSO | solvent_used | 26 | celsius | aggression | aggression | mean number of recordings | frequency of aggressive behaviour | count | NA | fig2a | oliveira_2024_fig2a | NA | NA | NA | 22 | 9.8398600 | 3.7105062 | NA | NA | 0.791082585 | study reports boxplot | exact sample size provided | NA | NA | NA | 24 | 4.8313245 | 1.6858765 | NA | NA | 0.344128109 | study reports boxplot | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Exposure to carbamate fungicide iodocarb does not affect reproductive behavior or milt volumes in precocious male brown trout (Salmo trutta L.) parr | 10.1007/s10695-020-00803-x | https://link.springer.com/article/10.1007/s10695-020-00803-x#citeas | Fish Physiology and Biochemistry | olsen_2020 | olsen_2020_exp_001 | olsen_2020_exp2_001 | olsen_2020_exp_001_assay_001 | olsen_2020_exp_001_assay2_001 | brown trout | Salmo trutta | not reported | NA | male | iodocarb | not reported | NA | NA | carbamate | 15 | ug/L | 96 | hours | ethanol | solvent_used | 8 | celsius | courting | courtship | time with females | time spent near potential mate | NA | NA | fig1 | olsen_2020_fig1 | NA | NA | NA | 5 | 550.3846154 | 90.9088724 | NA | NA | 18.18177448 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | 7 | 825.8241758 | 991.3480857 | NA | NA | 141.6211551 | calculated from scatter plot | counted from the scatter plot | NA | NA | NA | NA |
| NA | NA | NA | KM | Behavioral effects of triadimefon in zebrafish are associated with alterations of the dopaminergic and serotonergic pathways | 10.1016/j.pnpbp.2018.12.012 | https://www.sciencedirect.com/science/article/pii/S0278584618306961?via%3Dihub | Progress in Neuro-Psychopharmacology and Biological Psychiatry | paredes_2019 | paredes_2019_exp_001 | paredes_2019_exp2_001 | paredes_2019_exp_001_assay_001 | paredes_2019_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | triadimefon | not reported | 43121-43-3 | https://commonchemistry.cas.org/detail?cas_rn=43121-43-3&search=triadimefon | triazole | 5 | mg/L | not reported | not reported | DMSO | solvent_used | 28 | celsius | aggression | aggression | number of bites towards its reflex | frequency of aggressive behaviour | count | NA | fig7c | paredes_2019_fig7c | NA | NA | NA | 7 | 28.0900922 | 17.9394845 | NA | NA | 6.780487805 | study reports mean and se | states range of sample sizes so selected lowest | NA | NA | NA | 7 | 40.8934081 | 15.5769505 | NA | NA | 5.887533875 | study reports mean and se | states range of sample sizes so selected lowest | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_001 | sanchez_2021_exp_001_assay_001 | sanchez_2021_exp2_001_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | social interaction | sociality | duration | time spent in social zone | zone | NA | fig2a | sanchez_2021_fig2a | NA | NA | NA | 20 | 525.7969964 | 61.9000405 | NA | NA | 13.84126984 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 497.2493774 | 87.0469320 | NA | NA | 19.46428571 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_002 | sanchez_2021_exp_002_assay_001 | sanchez_2021_exp2_002_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | social interaction | sociality | duration | time spent in social zone | zone | NA | fig2a | sanchez_2021_fig2a | NA | NA | NA | 20 | 525.7969964 | 61.9000405 | NA | NA | 13.84126984 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 491.6263615 | 77.3750507 | NA | NA | 17.3015873 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_003 | sanchez_2021_exp_003_assay_001 | sanchez_2021_exp2_003_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | social interaction | sociality | duration | time spent in social zone | zone | NA | fig2a | sanchez_2021_fig2a | NA | NA | NA | 20 | 525.7969964 | 61.9000405 | NA | NA | 13.84126984 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 442.3168377 | 87.0469320 | NA | NA | 19.46428571 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_004 | sanchez_2021_exp_001_assay_002 | sanchez_2021_exp2_004_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | aggression | aggression | time close to mirror | time spent in aggression zone | zone | NA | fig2c | sanchez_2021_fig2c | NA | NA | NA | 20 | 448.8608098 | 84.6555719 | NA | NA | 18.92956134 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 476.5270917 | 70.5463099 | NA | NA | 15.77463445 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_005 | sanchez_2021_exp_002_assay_002 | sanchez_2021_exp2_005_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | aggression | aggression | time close to mirror | time spent in aggression zone | zone | NA | fig2c | sanchez_2021_fig2c | NA | NA | NA | 20 | 448.8608098 | 84.6555719 | NA | NA | 18.92956134 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 447.8900630 | 73.8022934 | NA | NA | 16.50269451 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_006 | sanchez_2021_exp_003_assay_002 | sanchez_2021_exp2_006_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | aggression | aggression | time close to mirror | time spent in aggression zone | zone | NA | fig2c | sanchez_2021_fig2c | NA | NA | NA | 20 | 448.8608098 | 84.6555719 | NA | NA | 18.92956134 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 462.9366374 | 73.8022934 | NA | NA | 16.50269451 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_007 | sanchez_2021_exp_001_assay_003 | sanchez_2021_exp2_007_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | time taken by pursuits | duration of courtship behaviour | NA | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 215.9100000 | 322.1726742 | NA | NA | 72.04 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 274.0000000 | 358.2180900 | NA | NA | 80.1 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_008 | sanchez_2021_exp_002_assay_003 | sanchez_2021_exp2_008_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | time taken by pursuits | duration of courtship behaviour | NA | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 215.9100000 | 322.1726742 | NA | NA | 72.04 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 98.0800000 | 109.5673309 | NA | NA | 24.5 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_009 | sanchez_2021_exp_003_assay_003 | sanchez_2021_exp2_009_assay_001 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | time taken by pursuits | duration of courtship behaviour | NA | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 215.9100000 | 322.1726742 | NA | NA | 72.04 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 158.2600000 | 188.3663664 | NA | NA | 42.12 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_007 | sanchez_2021_exp_001_assay_004 | sanchez_2021_exp2_007_assay_002 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of pursuits | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 43.7500000 | 27.3694720 | NA | NA | 6.12 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 40.5600000 | 38.7734187 | NA | NA | 8.67 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_008 | sanchez_2021_exp_002_assay_004 | sanchez_2021_exp2_008_assay_002 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of pursuits | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 43.7500000 | 27.3694720 | NA | NA | 6.12 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 21.3800000 | 27.2353080 | NA | NA | 6.09 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_009 | sanchez_2021_exp_003_assay_004 | sanchez_2021_exp2_009_assay_002 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of pursuits | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 43.7500000 | 27.3694720 | NA | NA | 6.12 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 36.7800000 | 33.7646265 | NA | NA | 7.55 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_007 | sanchez_2021_exp_001_assay_005 | sanchez_2021_exp2_007_assay_003 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | attempts at copulation | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 74.7100000 | 80.5878899 | NA | NA | 18.02 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 62.0000000 | 56.6619625 | NA | NA | 12.67 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_008 | sanchez_2021_exp_002_assay_005 | sanchez_2021_exp2_008_assay_003 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | attempts at copulation | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 74.7100000 | 80.5878899 | NA | NA | 18.02 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 28.2500000 | 47.8518547 | NA | NA | 10.7 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_009 | sanchez_2021_exp_003_assay_005 | sanchez_2021_exp2_009_assay_003 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | attempts at copulation | frequency of courtship behaviour | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 74.7100000 | 80.5878899 | NA | NA | 18.02 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 40.2200000 | 42.9325052 | NA | NA | 9.6 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp2_007 | sanchez_2021_exp_001_assay_006 | sanchez_2021_exp2_007_assay_004 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of actual copulations | frequency of courtship behaviour success | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 20.1300000 | 29.0241624 | NA | NA | 6.49 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 20.0000000 | 18.2463147 | NA | NA | 4.08 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp2_008 | sanchez_2021_exp_002_assay_006 | sanchez_2021_exp2_008_assay_004 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup transorb | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of actual copulations | frequency of courtship behaviour success | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 20.1300000 | 29.0241624 | NA | NA | 6.49 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 6.5000000 | 8.8548292 | NA | NA | 1.98 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | YY | KM | Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata | 10.1007/s11356-020-11958-8 | https://link.springer.com/article/10.1007/s11356-020-11958-8 | Environmental Science and Pollution Research | sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp2_009 | sanchez_2021_exp_003_assay_006 | sanchez_2021_exp2_009_assay_004 | killifish | Jenynsia multidentata | not reported | NA | mixed | roundup WG | commercial | 38641-94-0 | https://commonchemistry.cas.org/detail?cas_rn=38641-94-0&search=roundup | organophosphate | 0.5 | mg/L | 96 | hours | not reported | NA | 21.4 | celsius | sexual activity | courtship | number of actual copulations | frequency of courtship behaviour success | count | NA | table2 | sanchez_2021_table2 | NA | NA | NA | 20 | 20.1300000 | 29.0241624 | NA | NA | 6.49 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | 20 | 11.0000000 | 9.6598137 | NA | NA | 2.16 | study reports mean and se | states 10 males and 10 females | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp2_001 | schmidel_2014_exp_001_assay_001 | schmidel_2014_exp2_001_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 10 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | distance | group movement | NA | NA | fig1a | schmidel_2014_fig1a | 15.058824 | 128.000000 | 8 | 8 | 5.4751686 | 0.8400780 | 0.8400780 | 3.3603122 | 0.297012439 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 5.2221580 | 0.2800260 | 0.2800260 | 1.1201040 | 0.099004146 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp2_002 | schmidel_2014_exp_002_assay_001 | schmidel_2014_exp2_002_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 1000 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | distance | group movement | NA | NA | fig1a | schmidel_2014_fig1a | 15.058824 | 128.000000 | 8 | 8 | 5.4751686 | 0.8400780 | 0.8400780 | 3.3603122 | 0.297012439 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 6.8832275 | 1.8668401 | 1.8668401 | 7.4673604 | 0.660027643 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp2_003 | schmidel_2014_exp_001_assay_002 | schmidel_2014_exp2_003_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 10 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | nearest neighbour distance | group arrangment | NA | change | fig1b | schmidel_2014_fig1b | 15.058824 | 128.000000 | 8 | 8 | 2.3326796 | 0.2681029 | 0.2681029 | 1.0724116 | 0.094788686 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 2.1009739 | 0.1638407 | 0.1638407 | 0.6553626 | 0.057926419 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp2_004 | schmidel_2014_exp_002_assay_002 | schmidel_2014_exp2_004_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 1000 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | nearest neighbour distance | group arrangment | NA | change | fig1b | schmidel_2014_fig1b | 15.058824 | 128.000000 | 8 | 8 | 2.3326796 | 0.2681029 | 0.2681029 | 1.0724116 | 0.094788686 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 2.7960909 | 0.7894141 | 0.7894141 | 3.1576563 | 0.279100019 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp2_005 | schmidel_2014_exp_001_assay_003 | schmidel_2014_exp2_005_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 10 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | farthest neighbour distance | group arrangment | NA | change | fig1c | schmidel_2014_fig1c | 15.058824 | 128.000000 | 8 | 8 | 8.3946118 | 1.2046017 | 1.2046017 | 4.8184068 | 0.425891015 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 8.2799488 | 0.8339550 | 0.8339550 | 3.3358201 | 0.294847626 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp2_006 | schmidel_2014_exp_002_assay_003 | schmidel_2014_exp2_006_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 1000 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | farthest neighbour distance | group arrangment | NA | change | fig1c | schmidel_2014_fig1c | 15.058824 | 128.000000 | 8 | 8 | 8.3946118 | 1.2046017 | 1.2046017 | 4.8184068 | 0.425891015 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 10.8025340 | 2.9188426 | 2.9188426 | 11.6753703 | 1.03196669 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp2_007 | schmidel_2014_exp_001_assay_004 | schmidel_2014_exp2_007_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 10 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | shoal area | group arrangment | NA | change | fig2 | schmidel_2014_fig2 | 15.058824 | 128.000000 | 8 | 8 | 17.2624072 | 4.0968964 | 4.0968964 | 16.3875856 | 1.448471616 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 14.8327129 | 2.3788431 | 2.3788431 | 9.5153723 | 0.841048035 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp2_008 | schmidel_2014_exp_002_assay_004 | schmidel_2014_exp2_008_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 1000 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | shoal area | group arrangment | NA | change | fig2 | schmidel_2014_fig2 | 15.058824 | 128.000000 | 8 | 8 | 17.2624072 | 4.0968964 | 4.0968964 | 16.3875856 | 1.448471616 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 34.0322517 | 22.7398130 | 22.7398130 | 90.9592520 | 8.039737991 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp2_009 | schmidel_2014_exp_001_assay_005 | schmidel_2014_exp2_009_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 10 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | total number of interactions | group arrangment | NA | NA | fig3b | schmidel_2014_fig3b | 15.058824 | 128.000000 | 8 | 8 | 1432.0737130 | 253.6275665 | 253.6275665 | 1014.5102660 | 89.67088608 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 1519.7952320 | 148.8683542 | 148.8683542 | 595.4734169 | 52.63291139 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Subchronic atrazine exposure changes defensive behaviour profile and disrupts brain acetylcholinesterase activity of zebrafish | 10.1016/j.ntt.2014.05.006 | https://sciencedirect.com/science/article/pii/S0892036214001226 | Neurotoxicology and Teratology | schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp2_010 | schmidel_2014_exp_002_assay_005 | schmidel_2014_exp2_010_assay2_001 | zebrafish | Danio rerio | labratory stock from commercial supplier | not_wild | mixed | atrazine | analytical | 1912-24-9 | in paper | triazine | 1000 | ug/L | 14 | days | acetone | solvent_used | 27 | celsius | shoaling | collective behaviour | total number of interactions | group arrangment | NA | NA | fig3b | schmidel_2014_fig3b | 15.058824 | 128.000000 | 8 | 8 | 1432.0737130 | 253.6275665 | 253.6275665 | 1014.5102660 | 89.67088608 | study reports mean and se | exact sample size provided | 8.500000 | 8.000000 | 128 | 8 | 1067.5420670 | 358.3867787 | 358.3867788 | 1433.5471150 | 126.7088608 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies | 10.1371/journal.pone.0030611 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030611 | Plos One | shenoy_2012 | shenoy_2012_exp_001 | shenoy_2012_exp2_001 | shenoy_2012_exp_001_assay_001 | shenoy_2012_exp2_001_assay2_001 | guppy | Poecilia reticulata | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=1912-24-9 | triazine | 1 | ppb | 16 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | number of displays in absence of competing male | frequency of courtship behaviour | count | NA | fig2a | shenoy_2012_fig2a | NA | NA | NA | 17 | 19.8917569 | 8.3330673 | NA | NA | 2.021065675 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 17 | 14.1000516 | 11.8098620 | NA | NA | 2.864312268 | does not report error type | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies | 10.1371/journal.pone.0030611 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030611 | Plos One | shenoy_2012 | shenoy_2012_exp_002 | shenoy_2012_exp2_002 | shenoy_2012_exp_002_assay_001 | shenoy_2012_exp2_002_assay2_001 | guppy | Poecilia reticulata | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=1912-24-9 | triazine | 15 | ppb | 16 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | number of displays in absence of competing male | frequency of courtship behaviour | count | NA | fig2a | shenoy_2012_fig2a | NA | NA | NA | 17 | 19.8917569 | 8.3330673 | NA | NA | 2.021065675 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 17 | 13.2164759 | 11.4244385 | NA | NA | 2.770833333 | does not report error type | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies | 10.1371/journal.pone.0030611 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030611 | Plos One | shenoy_2012 | shenoy_2012_exp_001 | shenoy_2012_exp2_001 | shenoy_2012_exp_001_assay_002 | shenoy_2012_exp2_001_assay2_002 | guppy | Poecilia reticulata | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=1912-24-9 | triazine | 1 | ppb | 16 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | number of mating attempts in absence of competing male | frequency of courtship behaviour | count | NA | fig2b | shenoy_2012_fig2b | NA | NA | NA | 17 | 0.6531993 | 0.2939401 | NA | NA | 0.071290944 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 17 | 0.7630259 | 0.5163812 | NA | NA | 0.125240848 | does not report error type | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Environmentally Realistic Exposure to the Herbicide Atrazine Alters Some Sexually Selected Traits in Male Guppies | 10.1371/journal.pone.0030611 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030611 | Plos One | shenoy_2012 | shenoy_2012_exp_002 | shenoy_2012_exp2_002 | shenoy_2012_exp_002_assay_002 | shenoy_2012_exp2_002_assay2_002 | guppy | Poecilia reticulata | labratory stock from wild population | not_wild | male | atrazine | not reported | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=1912-24-9 | triazine | 15 | ppb | 16 | weeks | DMSO | solvent_used | 25 | celsius | courting | courtship | number of mating attempts in absence of competing male | frequency of courtship behaviour | count | NA | fig2b | shenoy_2012_fig2b | NA | NA | NA | 17 | 0.6531993 | 0.2939401 | NA | NA | 0.071290944 | study does not state error type used, so we assumed to be SE | exact sample size provided | NA | NA | NA | 17 | 0.5452995 | 0.4607710 | NA | NA | 0.111753372 | does not report error type | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Effects of chlorpyrifos on reproductive performances of guppy (Poecilia reticulata) | 10.1016/j.chemosphere.2004.10.030 | https://www.sciencedirect.com/science/article/pii/S0045653504009919 | Chemosphere | silva_2005 | silva_2005_exp_001 | silva_2005_exp2_001 | silva_2005_exp_001_assay_001 | silva_2005_exp2_001_assay2_001 | guppy | Poecilia reticulata | wild collected | wild | male | chlorpyrifos | commercial | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 0.002 | ug/L | 3 | days | not reported | NA | 26 | celsius | mating | courtship | number of gonopodial thrusts | frequency of courtship behaviour | count | NA | fig2 | silva_2005_fig2 | NA | NA | NA | 72 | 11.4702973 | 1.5373239 | NA | NA | 0.181175364 | study reports mean and se | exact sample size provided | NA | NA | NA | 72 | 7.7084288 | 1.2259155 | NA | NA | 0.144475526 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | GM | KM | Effects of chlorpyrifos on reproductive performances of guppy (Poecilia reticulata) | 10.1016/j.chemosphere.2004.10.030 | https://www.sciencedirect.com/science/article/pii/S0045653504009919 | Chemosphere | silva_2005 | silva_2005_exp_002 | silva_2005_exp2_002 | silva_2005_exp_002_assay_001 | silva_2005_exp2_002_assay2_001 | guppy | Poecilia reticulata | wild collected | wild | male | chlorpyrifos | commercial | 2921-88-2 | https://commonchemistry.cas.org/detail?cas_rn=2921-88-2&search=chlorpyrifos | organophosphate | 2 | ug/L | 3 | days | not reported | NA | 26 | celsius | mating | courtship | number of gonopodial thrusts | frequency of courtship behaviour | count | NA | fig2 | silva_2005_fig2 | NA | NA | NA | 72 | 11.4702973 | 1.5373239 | NA | NA | 0.181175364 | study reports mean and se | exact sample size provided | NA | NA | NA | 72 | 4.1219704 | 1.0746479 | NA | NA | 0.126648468 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_001 | stungaru_2019_exp_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 1 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 19.4069384 | 30.7277226 | NA | NA | 4.858479532 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 40.7818852 | 41.1839444 | NA | NA | 6.511753372 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_002 | stungaru_2019_exp_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 2 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 32.6771138 | 44.4864043 | NA | NA | 7.033918129 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 34.2701318 | 33.0631667 | NA | NA | 5.227745665 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_003 | stungaru_2019_exp_001_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 3 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 13.3157103 | 19.2621544 | NA | NA | 3.045614035 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 32.8944092 | 37.7036111 | NA | NA | 5.961464355 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_004 | stungaru_2019_exp_001_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 4 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.7309150 | 25.2242499 | NA | NA | 3.988304094 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 30.5098235 | 24.9423889 | NA | NA | 3.943737958 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_005 | stungaru_2019_exp_001_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 5 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 14.4759442 | 21.0966454 | NA | NA | 3.335672515 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 19.9626173 | 29.0027778 | NA | NA | 4.585741811 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_006 | stungaru_2019_exp_001_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 6 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 16.2888097 | 34.3967044 | NA | NA | 5.438596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 45.3676270 | 34.8033333 | NA | NA | 5.502890173 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_007 | stungaru_2019_exp_001_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 7 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 22.8151255 | 33.0208362 | NA | NA | 5.221052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 45.4593418 | 32.4831111 | NA | NA | 5.136030829 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_008 | stungaru_2019_exp_001_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 8 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.5671723 | 37.6070634 | NA | NA | 5.94619883 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 45.2759121 | 37.1235555 | NA | NA | 5.869749518 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_009 | stungaru_2019_exp_001_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 9 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 15.2736050 | 23.3897590 | NA | NA | 3.698245614 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 42.3410374 | 40.6038889 | NA | NA | 6.420038536 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_010 | stungaru_2019_exp_001_assay2_010 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 10 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 30.8642483 | 39.4415543 | NA | NA | 6.23625731 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 49.6782243 | 34.2232778 | NA | NA | 5.411175337 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_011 | stungaru_2019_exp_001_assay2_011 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 11 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.1444819 | 37.6637749 | NA | NA | 5.955165692 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 46.7433495 | 33.6432222 | NA | NA | 5.319460501 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_012 | stungaru_2019_exp_001_assay2_012 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 12 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.0060804 | 28.3926918 | NA | NA | 4.489278752 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 63.9181618 | 23.2948361 | NA | NA | 3.683236994 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_013 | stungaru_2019_exp_001_assay2_013 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 13 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 40.0704078 | 46.9348579 | NA | NA | 7.421052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 47.1875260 | 32.7707017 | NA | NA | 5.18150289 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_014 | stungaru_2019_exp_001_assay2_014 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 14 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 21.1971135 | 37.0843322 | NA | NA | 5.863547758 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 49.3724971 | 28.0327689 | NA | NA | 4.432369942 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp2_001 | stungaru_2019_exp_001_assay_015 | stungaru_2019_exp_001_assay2_015 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.25 | ug/L | 15 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1b treatment; fig1a control | stungaru_2019_fig1b_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 45.9339556 | 39.4021029 | NA | NA | 6.230019493 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 54.0545780 | 38.2982899 | NA | NA | 6.055491329 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_001 | stungaru_2019_exp_002_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 1 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 19.4069384 | 30.7277226 | NA | NA | 4.858479532 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 41.3431110 | 46.6391789 | NA | NA | 7.374301676 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_002 | stungaru_2019_exp_002_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 2 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 32.6771138 | 44.4864043 | NA | NA | 7.033918129 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 60.7839819 | 34.1119553 | NA | NA | 5.393573711 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_003 | stungaru_2019_exp_002_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 3 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 13.3157103 | 19.2621544 | NA | NA | 3.045614035 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 51.6423315 | 37.0027990 | NA | NA | 5.850656229 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_004 | stungaru_2019_exp_002_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 4 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.7309150 | 25.2242499 | NA | NA | 3.988304094 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 36.4671920 | 30.6429429 | NA | NA | 4.845074689 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_005 | stungaru_2019_exp_002_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 5 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 14.4759442 | 21.0966454 | NA | NA | 3.335672515 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 48.5341704 | 31.2211116 | NA | NA | 4.936491193 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_006 | stungaru_2019_exp_002_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 6 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 16.2888097 | 34.3967044 | NA | NA | 5.438596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 58.9556518 | 49.7225111 | NA | NA | 7.861819307 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_007 | stungaru_2019_exp_002_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 7 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 22.8151255 | 33.0208362 | NA | NA | 5.221052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 56.7616557 | 46.2534987 | NA | NA | 7.313320286 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_008 | stungaru_2019_exp_002_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 8 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.5671723 | 37.6070634 | NA | NA | 5.94619883 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 59.0470683 | 41.0499801 | NA | NA | 6.490571754 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_009 | stungaru_2019_exp_002_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 9 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 15.2736050 | 23.3897590 | NA | NA | 3.698245614 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 59.1384848 | 50.3006799 | NA | NA | 7.953235811 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_010 | stungaru_2019_exp_002_assay2_010 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 10 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 30.8642483 | 39.4415543 | NA | NA | 6.23625731 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 64.3492255 | 45.0971613 | NA | NA | 7.130487279 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_011 | stungaru_2019_exp_002_assay2_011 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 11 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.1444819 | 37.6637749 | NA | NA | 5.955165692 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 65.7204731 | 54.3478610 | NA | NA | 8.593151336 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_012 | stungaru_2019_exp_002_assay2_012 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 12 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.0060804 | 28.3926918 | NA | NA | 4.489278752 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 63.7093100 | 37.5809677 | NA | NA | 5.942072732 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_013 | stungaru_2019_exp_002_assay2_013 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 13 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 40.0704078 | 46.9348579 | NA | NA | 7.421052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 66.8174711 | 34.6901240 | NA | NA | 5.484990214 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_014 | stungaru_2019_exp_002_assay2_014 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 14 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 21.1971135 | 37.0843322 | NA | NA | 5.863547758 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 65.6055131 | 39.2428647 | NA | NA | 6.204841713 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp2_002 | stungaru_2019_exp_002_assay_015 | stungaru_2019_exp_002_assay2_015 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 0.5 | ug/L | 15 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1c treatment; fig1a control | stungaru_2019_fig1c_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 45.9339556 | 39.4021029 | NA | NA | 6.230019493 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 66.2703176 | 38.6422086 | NA | NA | 6.109869646 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_001 | stungaru_2019_exp_003_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 1 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 19.4069384 | 30.7277226 | NA | NA | 4.858479532 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 29.4996597 | 20.9557904 | NA | NA | 3.313401392 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_002 | stungaru_2019_exp_003_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 2 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 32.6771138 | 44.4864043 | NA | NA | 7.033918129 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 45.8181616 | 18.8602114 | NA | NA | 2.982061253 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_003 | stungaru_2019_exp_003_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 3 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 13.3157103 | 19.2621544 | NA | NA | 3.045614035 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 36.1264625 | 55.0089498 | NA | NA | 8.697678654 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_004 | stungaru_2019_exp_003_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 4 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.7309150 | 25.2242499 | NA | NA | 3.988304094 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 28.1742991 | 30.9097908 | NA | NA | 4.887267053 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_005 | stungaru_2019_exp_003_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 5 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 14.4759442 | 21.0966454 | NA | NA | 3.335672515 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 41.6764098 | 40.3398965 | NA | NA | 6.37829768 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_006 | stungaru_2019_exp_003_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 6 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 16.2888097 | 34.3967044 | NA | NA | 5.438596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 30.0795049 | 27.7664223 | NA | NA | 4.390256844 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_007 | stungaru_2019_exp_003_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 7 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 22.8151255 | 33.0208362 | NA | NA | 5.221052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 48.7173878 | 34.5770542 | NA | NA | 5.467112297 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_008 | stungaru_2019_exp_003_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 8 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.5671723 | 37.6070634 | NA | NA | 5.94619883 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 52.2792943 | 37.7204227 | NA | NA | 5.964122506 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_009 | stungaru_2019_exp_003_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 9 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 15.2736050 | 23.3897590 | NA | NA | 3.698245614 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 42.2562551 | 31.9575804 | NA | NA | 5.052937123 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_010 | stungaru_2019_exp_003_assay2_010 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 10 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 30.8642483 | 39.4415543 | NA | NA | 6.23625731 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 44.1614609 | 41.3876860 | NA | NA | 6.543967749 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_011 | stungaru_2019_exp_003_assay2_011 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 11 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.1444819 | 37.6637749 | NA | NA | 5.955165692 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 50.6225936 | 24.6230537 | NA | NA | 3.893246636 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_012 | stungaru_2019_exp_003_assay2_012 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 12 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.0060804 | 28.3926918 | NA | NA | 4.489278752 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 33.8899165 | 27.2425275 | NA | NA | 4.30742181 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_013 | stungaru_2019_exp_003_assay2_013 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 13 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 40.0704078 | 46.9348579 | NA | NA | 7.421052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 48.2203776 | 30.3858961 | NA | NA | 4.804432018 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_014 | stungaru_2019_exp_003_assay2_014 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 14 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 21.1971135 | 37.0843322 | NA | NA | 5.863547758 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 48.3032126 | 35.6248437 | NA | NA | 5.632782366 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp2_003 | stungaru_2019_exp_003_assay_015 | stungaru_2019_exp_003_assay2_015 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 1 | ug/L | 15 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1d treatment; fig1a control | stungaru_2019_fig1d_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 45.9339556 | 39.4021029 | NA | NA | 6.230019493 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 48.2203776 | 38.7682122 | NA | NA | 6.129792575 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_001 | stungaru_2019_exp_004_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 1 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 19.4069384 | 30.7277226 | NA | NA | 4.858479532 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 35.2396820 | 45.4287155 | NA | NA | 7.182910613 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_002 | stungaru_2019_exp_004_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 2 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 32.6771138 | 44.4864043 | NA | NA | 7.033918129 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 31.1165532 | 33.8514678 | NA | NA | 5.352387017 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_003 | stungaru_2019_exp_004_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 3 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 13.3157103 | 19.2621544 | NA | NA | 3.045614035 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 37.3774530 | 29.2041743 | NA | NA | 4.617585394 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_004 | stungaru_2019_exp_004_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 4 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.7309150 | 25.2242499 | NA | NA | 3.988304094 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 26.9451305 | 32.9899006 | NA | NA | 5.216161278 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_005 | stungaru_2019_exp_004_assay2_005 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 5 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 14.4759442 | 21.0966454 | NA | NA | 3.335672515 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 37.9760289 | 35.1531727 | NA | NA | 5.558204641 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_006 | stungaru_2019_exp_004_assay2_006 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 6 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 16.2888097 | 34.3967044 | NA | NA | 5.438596491 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 49.1779490 | 38.9388990 | NA | NA | 6.156780525 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_007 | stungaru_2019_exp_004_assay2_007 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 7 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 22.8151255 | 33.0208362 | NA | NA | 5.221052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 50.5461225 | 34.6123547 | NA | NA | 5.4726938 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_008 | stungaru_2019_exp_004_assay2_008 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 8 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.5671723 | 37.6070634 | NA | NA | 5.94619883 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 50.1185683 | 32.9899006 | NA | NA | 5.216161278 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_009 | stungaru_2019_exp_004_assay2_009 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 9 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 15.2736050 | 23.3897590 | NA | NA | 3.698245614 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 49.8620358 | 37.3164449 | NA | NA | 5.900248003 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_010 | stungaru_2019_exp_004_assay2_010 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 10 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 30.8642483 | 39.4415543 | NA | NA | 6.23625731 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 54.9926862 | 29.2041743 | NA | NA | 4.617585394 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_011 | stungaru_2019_exp_004_assay2_011 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 11 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 26.1444819 | 37.6637749 | NA | NA | 5.955165692 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 39.9427783 | 41.6429892 | NA | NA | 6.584334728 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_012 | stungaru_2019_exp_004_assay2_012 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 12 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 20.0060804 | 28.3926918 | NA | NA | 4.489278752 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 53.4534911 | 28.6633562 | NA | NA | 4.532074553 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_013 | stungaru_2019_exp_004_assay2_013 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 13 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 40.0704078 | 46.9348579 | NA | NA | 7.421052632 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 50.3751008 | 36.2348088 | NA | NA | 5.729226322 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_014 | stungaru_2019_exp_004_assay2_014 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 14 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 21.1971135 | 37.0843322 | NA | NA | 5.863547758 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 42.5936143 | 29.2041743 | NA | NA | 4.617585394 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community | 10.1016/j.ecoenv.2019.01.057 | https://www.sciencedirect.com/science/article/pii/S0147651319300661?via%3Dihub | Ecotoxicology and Environmental Safety | stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp2_004 | stungaru_2019_exp_004_assay_015 | stungaru_2019_exp_004_assay2_015 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | deltamethrin | not reported | 52918-63-5 | https://commonchemistry.cas.org/detail?cas_rn=52918-63-5&search=deltamethrin | pyrethroid | 2 | ug/L | 15 | days | not reported | NA | 24 | celsius | aggression | aggression | percentage of time in left arm | time spent in aggression zone | zone | NA | fig1e treatment; fig1a control | stungaru_2019_fig1e_treatment; stungaru_2019_fig1a_control | NA | NA | NA | 40 | 45.9339556 | 39.4021029 | NA | NA | 6.230019493 | study reports mean and se | exact sample size provided | NA | NA | NA | 40 | 49.6910141 | 29.7449923 | NA | NA | 4.703096234 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| 150 across 5 groups - took n = 30 | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_001 | tamagno_2023_exp2_001 | tamagno_2023_exp_001_assay_001 | tamagno_2023_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | prallethrin | commercial | 23031-36-9 | https://commonchemistry.cas.org/detail?cas_rn=23031-36-9&search=prallethrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | social interaction | sociality | time in conspecific segment | time spent in social zone | zone | NA | fig3b | tamagno_2023_fig3b | NA | NA | NA | NA | 79.1972873 | NA | NA | NA | 7.943262411 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA | 62.6017278 | NA | NA | NA | 5.644208038 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| 150 across 5 groups - took n = 30 | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_002 | tamagno_2023_exp2_002 | tamagno_2023_exp_002_assay_001 | tamagno_2023_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | prallethrin | commercial | 23031-36-9 | https://commonchemistry.cas.org/detail?cas_rn=23031-36-9&search=prallethrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | social interaction | sociality | time in conspecific segment | time spent in social zone | zone | NA | fig3b | tamagno_2023_fig3b | NA | NA | NA | NA | 79.1972873 | NA | NA | NA | 7.943262411 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA | 33.4776143 | NA | NA | NA | 6.885933806 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| 150 across 5 groups - took n = 30 | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_003 | tamagno_2023_exp2_003 | tamagno_2023_exp_003_assay_001 | tamagno_2023_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | transfluthrin | commercial | 118712-89-3 | https://commonchemistry.cas.org/detail?cas_rn=118712-89-3&search=transfluthrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | social interaction | sociality | time in conspecific segment | time spent in social zone | zone | NA | fig3b | tamagno_2023_fig3b | NA | NA | NA | NA | 79.1972873 | NA | NA | NA | 7.943262411 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA | 39.6989173 | NA | NA | NA | 8.441489362 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| 150 across 5 groups - took n = 30 | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_004 | tamagno_2023_exp2_004 | tamagno_2023_exp_004_assay_001 | tamagno_2023_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | transfluthrin | commercial | 118712-89-3 | https://commonchemistry.cas.org/detail?cas_rn=118712-89-3&search=transfluthrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | social interaction | sociality | time in conspecific segment | time spent in social zone | zone | NA | fig3b | tamagno_2023_fig3b | NA | NA | NA | NA | 79.1972873 | NA | NA | NA | 7.943262411 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA | 49.2414705 | NA | NA | NA | 8.196808511 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| NA | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_001 | tamagno_2023_exp2_005 | tamagno_2023_exp_001_assay_002 | tamagno_2023_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | prallethrin | commercial | 23031-36-9 | https://commonchemistry.cas.org/detail?cas_rn=23031-36-9&search=prallethrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | shoaling test | collective behaviour | distance among fish in a shoal | group arrangment | NA | change | fig4 | tamagno_2023_fig4 | 1.600000 | 1.000000 | 4 | 4 | 10.8954991 | 1.0286458 | 0.5143229 | 1.0286458 | 0.514322917 | study reports mean and se | Four fish of each concentration were placed in the aquarium and were kept for 1<a0>min during the acclimatization period. | 1.600000 | 1.000000 | 4 | 4 | 16.0570202 | 1.5274306 | 0.7637153 | 1.5274306 | 0.763715278 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| NA | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_002 | tamagno_2023_exp2_006 | tamagno_2023_exp_002_assay_002 | tamagno_2023_exp2_006_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | prallethrin | commercial | 23031-36-9 | https://commonchemistry.cas.org/detail?cas_rn=23031-36-9&search=prallethrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | shoaling test | collective behaviour | distance among fish in a shoal | group arrangment | NA | change | fig4 | tamagno_2023_fig4 | 1.600000 | 1.000000 | 4 | 4 | 10.8954991 | 1.0286458 | 0.5143229 | 1.0286458 | 0.514322917 | study reports mean and se | Four fish of each concentration were placed in the aquarium and were kept for 1<a0>min during the acclimatization period. | 1.600000 | 1.000000 | 4 | 4 | 16.1352820 | 1.4444444 | 0.7222222 | 1.4444444 | 0.722222222 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| NA | NA | GM | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_003 | tamagno_2023_exp2_007 | tamagno_2023_exp_003_assay_002 | tamagno_2023_exp2_007_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | transfluthrin | commercial | 118712-89-3 | https://commonchemistry.cas.org/detail?cas_rn=118712-89-3&search=transfluthrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | shoaling test | collective behaviour | distance among fish in a shoal | group arrangment | NA | change | fig4 | tamagno_2023_fig4 | 1.600000 | 1.000000 | 4 | 4 | 10.8954991 | 1.0286458 | 0.5143229 | 1.0286458 | 0.514322917 | study reports mean and se | Four fish of each concentration were placed in the aquarium and were kept for 1<a0>min during the acclimatization period. | 1.600000 | 1.000000 | 4 | 4 | 15.3541417 | 1.4875000 | 0.7437500 | 1.4875000 | 0.74375 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| NA | NA | NA | KM | Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions | 10.1016/j.neuro.2023.02.011 | https://www.sciencedirect.com/science/article/pii/S0161813X23000323?via%3Dihub | Neurotoxicology | tamagno_2023 | tamagno_2023_exp_004 | tamagno_2023_exp2_008 | tamagno_2023_exp_004_assay_002 | tamagno_2023_exp2_008_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | not reported | transfluthrin | commercial | 118712-89-3 | https://commonchemistry.cas.org/detail?cas_rn=118712-89-3&search=transfluthrin | pyrethroid | not reported | not reported | 7 | days | not reported | NA | 28 | celsius | shoaling test | collective behaviour | distance among fish in a shoal | group arrangment | NA | change | fig4 | tamagno_2023_fig4 | 1.600000 | 1.000000 | 4 | 4 | 10.8954991 | 1.0286458 | 0.5143229 | 1.0286458 | 0.514322917 | study reports mean and se | Four fish of each concentration were placed in the aquarium and were kept for 1<a0>min during the acclimatization period. | 1.600000 | 1.000000 | 4 | 4 | 16.3148369 | 1.3333333 | 0.6666667 | 1.3333333 | 0.666666667 | study reports mean and se but no sample size | no sample size reported | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-7 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_001 | teather_2001_exp2_001 | teather_2001_exp_001_assay_001 | teather_2001_exp2_001_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | acrobat | commercial | 119446-68-3 | https://commonchemistry.cas.org/detail?cas_rn=119446-68-3&search=difenoconazole | triazole | 0.4 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3a | teather_2001_fig3a | NA | NA | NA | 20 | 51.1581869 | 38.3355721 | NA | NA | 8.572094508 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 34.3267729 | 26.2993579 | NA | NA | 5.880715198 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-8 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_002 | teather_2001_exp2_002 | teather_2001_exp_002_assay_001 | teather_2001_exp2_002_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | acrobat | commercial | 119446-68-3 | https://commonchemistry.cas.org/detail?cas_rn=119446-68-3&search=difenoconazole | triazole | 1 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3a | teather_2001_fig3a | NA | NA | NA | 20 | 51.1581869 | 38.3355721 | NA | NA | 8.572094508 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 17.1201586 | 10.5614307 | NA | NA | 2.361607705 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-9 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_003 | teather_2001_exp2_003 | teather_2001_exp_003_assay_001 | teather_2001_exp2_003_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | acrobat | commercial | 119446-68-3 | https://commonchemistry.cas.org/detail?cas_rn=119446-68-3&search=difenoconazole | triazole | 2 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3a | teather_2001_fig3a | NA | NA | NA | 20 | 51.1581869 | 38.3355721 | NA | NA | 8.572094508 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 14.0697487 | 18.4825038 | NA | NA | 4.132813484 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-10 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_004 | teather_2001_exp2_004 | teather_2001_exp_004_assay_001 | teather_2001_exp2_004_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | tattoo c | commercial | 1897-45-6 | https://commonchemistry.cas.org/detail?cas_rn=1897-45-6&search=chlorothalonil | organochlorine | 0.04 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3b | teather_2001_fig3b | NA | NA | NA | 20 | 51.1562994 | 38.3404452 | NA | NA | 8.573184176 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 22.5838814 | 28.8687687 | NA | NA | 6.455252918 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-11 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_005 | teather_2001_exp2_005 | teather_2001_exp_005_assay_001 | teather_2001_exp2_005_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | tattoo c | commercial | 1897-45-6 | https://commonchemistry.cas.org/detail?cas_rn=1897-45-6&search=chlorothalonil | organochlorine | 0.1 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3b | teather_2001_fig3b | NA | NA | NA | 20 | 51.1562994 | 38.3404452 | NA | NA | 8.573184176 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 30.0891991 | 40.0955121 | NA | NA | 8.965629053 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Effects of Acrobat MZ<ae> and Tattoo C<ae> on Japanese medaka (Oryzias latipes) development and adult male behavior | 10.1016/S0166-445X(00)00124-12 | https://www.sciencedirect.com/science/article/pii/S0166445X00001247 | Aquatic Toxicology | teather_2001 | teather_2001_exp_006 | teather_2001_exp2_006 | teather_2001_exp_006_assay_001 | teather_2001_exp2_006_assay_001 | Japanese medaka | Oryzias latipes | not reported | NA | male | tattoo c | commercial | 1897-45-6 | https://commonchemistry.cas.org/detail?cas_rn=1897-45-6&search=chlorothalonil | organochlorine | 0.2 | mg/L | 28 | days | none | none | 25 | celsius | courting | courtship | number of approaches to female | frequency of courtship behaviour | count | NA | fig3b | teather_2001_fig3b | NA | NA | NA | 20 | 51.1562994 | 38.3404452 | NA | NA | 8.573184176 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | 20 | 20.9542790 | 22.1905820 | NA | NA | 4.961964981 | study reports mean and se | exact sample size provided in text (Section 2.3.1) | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_001 | yan_2023_exp2_001 | yan_2023_exp_001_assay_001 | yan_2023_exp2_001_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 5.0701778 | 2.0072727 | NA | NA | 0.501818182 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.0765728 | 1.0036364 | NA | NA | 0.250909091 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_001 | yan_2023_exp2_001 | yan_2023_exp_001_assay_002 | yan_2023_exp2_001_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.0802092 | 1.8342320 | NA | NA | 0.458557994 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.0765728 | 1.0036364 | NA | NA | 0.250909091 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_002 | yan_2023_exp2_002 | yan_2023_exp_002_assay_001 | yan_2023_exp2_002_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 5.0701778 | 2.0072727 | NA | NA | 0.501818182 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.5783910 | 1.4189342 | NA | NA | 0.354733542 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_002 | yan_2023_exp2_002 | yan_2023_exp_002_assay_002 | yan_2023_exp2_002_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.0802092 | 1.8342320 | NA | NA | 0.458557994 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.5783910 | 1.4189342 | NA | NA | 0.354733542 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_003 | yan_2023_exp2_003 | yan_2023_exp_003_assay_001 | yan_2023_exp2_003_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 5.0701778 | 2.0072727 | NA | NA | 0.501818182 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.3400961 | 1.1680251 | NA | NA | 0.29200627 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_003 | yan_2023_exp2_003 | yan_2023_exp_003_assay_002 | yan_2023_exp2_003_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.0802092 | 1.8342320 | NA | NA | 0.458557994 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.3400961 | 1.1680251 | NA | NA | 0.29200627 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_004 | yan_2023_exp2_004 | yan_2023_exp_004_assay_001 | yan_2023_exp2_004_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.5947905 | 0.9220063 | NA | NA | 0.230501567 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 3.0748219 | 2.0798746 | NA | NA | 0.519968652 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_004 | yan_2023_exp2_004 | yan_2023_exp_004_assay_002 | yan_2023_exp2_004_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.5602137 | 1.2436364 | NA | NA | 0.310909091 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 3.0748219 | 2.0798746 | NA | NA | 0.519968652 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_005 | yan_2023_exp2_005 | yan_2023_exp_005_assay_001 | yan_2023_exp2_005_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.5947905 | 0.9220063 | NA | NA | 0.230501567 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.7293360 | 0.7933542 | NA | NA | 0.198338558 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_005 | yan_2023_exp2_005 | yan_2023_exp_005_assay_002 | yan_2023_exp2_005_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.5602137 | 1.2436364 | NA | NA | 0.310909091 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.7293360 | 0.7933542 | NA | NA | 0.198338558 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_006 | yan_2023_exp2_006 | yan_2023_exp_006_assay_001 | yan_2023_exp2_006_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 3.5947905 | 0.9220063 | NA | NA | 0.230501567 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.3779567 | 1.2007524 | NA | NA | 0.300188088 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_006 | yan_2023_exp2_006 | yan_2023_exp_006_assay_002 | yan_2023_exp2_006_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.5602137 | 1.2436364 | NA | NA | 0.310909091 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.3779567 | 1.2007524 | NA | NA | 0.300188088 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_007 | yan_2023_exp2_007 | yan_2023_exp_007_assay_001 | yan_2023_exp2_007_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.3643288 | 0.9630094 | NA | NA | 0.240752351 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.2884667 | 0.4815047 | NA | NA | 0.120376176 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_007 | yan_2023_exp2_007 | yan_2023_exp_007_assay_002 | yan_2023_exp2_007_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.0821971 | 0.4664577 | NA | NA | 0.11661442 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.2884667 | 0.4815047 | NA | NA | 0.120376176 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_008 | yan_2023_exp2_008 | yan_2023_exp_008_assay_001 | yan_2023_exp2_008_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.3643288 | 0.9630094 | NA | NA | 0.240752351 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.0972441 | 0.4062696 | NA | NA | 0.101567398 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_008 | yan_2023_exp2_008 | yan_2023_exp_008_assay_002 | yan_2023_exp2_008_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.0821971 | 0.4664577 | NA | NA | 0.11661442 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 2.0972441 | 0.4062696 | NA | NA | 0.101567398 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_009 | yan_2023_exp2_009 | yan_2023_exp_009_assay_001 | yan_2023_exp2_009_assay2_001 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.3643288 | 0.9630094 | NA | NA | 0.240752351 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.4803162 | 0.3310345 | NA | NA | 0.082758621 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_009 | yan_2023_exp2_009 | yan_2023_exp_009_assay_002 | yan_2023_exp2_009_assay2_002 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | number of contacts | frequency of social behaviour | count | NA | fig4d | yan_2023_fig4d | NA | NA | NA | 16 | 2.0821971 | 0.4664577 | NA | NA | 0.11661442 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 1.4803162 | 0.3310345 | NA | NA | 0.082758621 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_001 | yan_2023_exp2_001 | yan_2023_exp_001_assay_003 | yan_2023_exp2_001_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.6531373 | 0.2295338 | NA | NA | 0.057383459 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2875834 | 0.0977644 | NA | NA | 0.024441103 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_001 | yan_2023_exp2_001 | yan_2023_exp_001_assay_004 | yan_2023_exp2_001_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3439042 | 0.6630977 | NA | NA | 0.165774436 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2875834 | 0.0977644 | NA | NA | 0.024441103 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_002 | yan_2023_exp2_002 | yan_2023_exp_002_assay_003 | yan_2023_exp2_002_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.6531373 | 0.2295338 | NA | NA | 0.057383459 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3747213 | 0.3145464 | NA | NA | 0.078636591 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_002 | yan_2023_exp2_002 | yan_2023_exp_002_assay_004 | yan_2023_exp2_002_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3439042 | 0.6630977 | NA | NA | 0.165774436 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3747213 | 0.3145464 | NA | NA | 0.078636591 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_003 | yan_2023_exp2_003 | yan_2023_exp_003_assay_003 | yan_2023_exp2_003_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.6531373 | 0.2295338 | NA | NA | 0.057383459 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.4182902 | 0.6035890 | NA | NA | 0.150897243 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_003 | yan_2023_exp2_003 | yan_2023_exp_003_assay_004 | yan_2023_exp2_003_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | female | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3439042 | 0.6630977 | NA | NA | 0.165774436 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.4182902 | 0.6035890 | NA | NA | 0.150897243 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_004 | yan_2023_exp2_004 | yan_2023_exp_004_assay_003 | yan_2023_exp2_004_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3943922 | 0.1235288 | NA | NA | 0.030882206 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3462970 | 0.2146566 | NA | NA | 0.05366416 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_004 | yan_2023_exp2_004 | yan_2023_exp_004_assay_004 | yan_2023_exp2_004_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3204774 | 0.1680802 | NA | NA | 0.04202005 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3462970 | 0.2146566 | NA | NA | 0.05366416 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_005 | yan_2023_exp2_005 | yan_2023_exp_005_assay_003 | yan_2023_exp2_005_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3943922 | 0.1235288 | NA | NA | 0.030882206 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2850388 | 0.1721303 | NA | NA | 0.043032581 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_005 | yan_2023_exp2_005 | yan_2023_exp_005_assay_004 | yan_2023_exp2_005_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3204774 | 0.1680802 | NA | NA | 0.04202005 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2850388 | 0.1721303 | NA | NA | 0.043032581 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_006 | yan_2023_exp2_006 | yan_2023_exp_006_assay_003 | yan_2023_exp2_006_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3943922 | 0.1235288 | NA | NA | 0.030882206 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3194649 | 0.2592080 | NA | NA | 0.064802005 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_006 | yan_2023_exp2_006 | yan_2023_exp_006_assay_004 | yan_2023_exp2_006_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | male | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3204774 | 0.1680802 | NA | NA | 0.04202005 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.3194649 | 0.2592080 | NA | NA | 0.064802005 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_007 | yan_2023_exp2_007 | yan_2023_exp_007_assay_003 | yan_2023_exp2_007_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.4124113 | 0.1954887 | NA | NA | 0.04887218 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2808323 | 0.0481203 | NA | NA | 0.012030075 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_007 | yan_2023_exp2_007 | yan_2023_exp_007_assay_004 | yan_2023_exp2_007_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.4 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3214338 | 0.0691729 | NA | NA | 0.017293233 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2808323 | 0.0481203 | NA | NA | 0.012030075 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_008 | yan_2023_exp2_008 | yan_2023_exp_008_assay_003 | yan_2023_exp2_008_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.4124113 | 0.1954887 | NA | NA | 0.04887218 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2176744 | 0.0812030 | NA | NA | 0.020300752 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_008 | yan_2023_exp2_008 | yan_2023_exp_008_assay_004 | yan_2023_exp2_008_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 0.8 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3214338 | 0.0691729 | NA | NA | 0.017293233 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2176744 | 0.0812030 | NA | NA | 0.020300752 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_009 | yan_2023_exp2_009 | yan_2023_exp_009_assay_003 | yan_2023_exp2_009_assay2_003 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | none | none | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.4124113 | 0.1954887 | NA | NA | 0.04887218 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2748173 | 0.0751880 | NA | NA | 0.018796992 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Molecular Mechanisms of Tebuconazole Affecting the Social Behavior and Reproduction of Zebrafish | <a0>10.3390/ijerph20053928 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002025/#:~:text=Consequently%2C%20TEB%20might%20influence%20the,affecting%20the%20reproduction%20of%20zebrafish. | Environmental Research and Public Health | yan_2023 | yan_2023_exp_009 | yan_2023_exp2_009 | yan_2023_exp_009_assay_004 | yan_2023_exp2_009_assay2_004 | zebrafish | Danio rerio | commercial supplier | not_wild | mixed | tebuconazole | analytical | 107534-96-3 | in paper | triazole | 1.6 | mg/L | 21 | days | DMSO | solvent_used | 27 | celsius | social interaction | sociality | contact time | duration of social behaviour | NA | NA | fig4e | yan_2023_fig4e | NA | NA | NA | 16 | 0.3214338 | 0.0691729 | NA | NA | 0.017293233 | study reports mean and se | exact sample size provided | NA | NA | NA | 16 | 0.2748173 | 0.0751880 | NA | NA | 0.018796992 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_001 | yang_2023_exp_001_assay_001 | yang_2023_exp2_001_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | shoaling average speed | group movement | NA | NA | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 5.9100000 | 0.9800000 | 0.4900000 | 0.9800000 | 0.200041662 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 5.8000000 | 0.9800000 | 0.4900000 | 0.9800000 | 0.200041662 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_002 | yang_2023_exp_002_assay_001 | yang_2023_exp2_002_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | shoaling average speed | group movement | NA | NA | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 5.9100000 | 0.9800000 | 0.4900000 | 0.9800000 | 0.200041662 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 6.2400000 | 0.7700000 | 0.3850000 | 0.7700000 | 0.157175592 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_003 | yang_2023_exp_003_assay_001 | yang_2023_exp2_003_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | shoaling average speed | group movement | NA | NA | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 5.9100000 | 0.9800000 | 0.4900000 | 0.9800000 | 0.200041662 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 6.7500000 | 0.9000000 | 0.4500000 | 0.9000000 | 0.183711731 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_001 | yang_2023_exp_001_assay_002 | yang_2023_exp2_001_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | average fish distance | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 6.3100000 | 0.8100000 | 0.4050000 | 0.8100000 | 0.165340558 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 5.6700000 | 0.5800000 | 0.2900000 | 0.5800000 | 0.118392004 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_002 | yang_2023_exp_002_assay_002 | yang_2023_exp2_002_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | average fish distance | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 6.3100000 | 0.8100000 | 0.4050000 | 0.8100000 | 0.165340558 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 5.8700000 | 0.6200000 | 0.3100000 | 0.6200000 | 0.12655697 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_003 | yang_2023_exp_003_assay_002 | yang_2023_exp2_003_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | average fish distance | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 6.3100000 | 0.8100000 | 0.4050000 | 0.8100000 | 0.165340558 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 4.8400000 | 1.0400000 | 0.5200000 | 1.0400000 | 0.212289111 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_001 | yang_2023_exp_001_assay_003 | yang_2023_exp2_001_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | maximum inter-fish difference | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 18.2300000 | 0.7300000 | 0.3650000 | 0.7300000 | 0.149010626 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 17.6400000 | 0.7200000 | 0.3600000 | 0.7200000 | 0.146969385 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_002 | yang_2023_exp_002_assay_003 | yang_2023_exp2_002_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | maximum inter-fish difference | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 18.2300000 | 0.7300000 | 0.3650000 | 0.7300000 | 0.149010626 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 18.1300000 | 0.6600000 | 0.3300000 | 0.6600000 | 0.134721936 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_003 | yang_2023_exp_003_assay_003 | yang_2023_exp2_003_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | shoaling | collective behaviour | maximum inter-fish difference | group arrangment | NA | change | tables4 | yang_2023_tables4 | 9.600000 | 6.000000 | 24 | 24 | 18.2300000 | 0.7300000 | 0.3650000 | 0.7300000 | 0.149010626 | study reports mean and sd | exact sample size provided | 9.600000 | 6.000000 | 24 | 24 | 17.5100000 | 1.2800000 | 0.6400000 | 1.2800000 | 0.261278906 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_004 | yang_2023_exp_001_assay_004 | yang_2023_exp2_004_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | social preference | sociality | time spent in social zone | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 482.7000000 | 92.8100000 | NA | NA | 21.87552679 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 535.7000000 | 80.7200000 | NA | NA | 19.02588646 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_005 | yang_2023_exp_002_assay_004 | yang_2023_exp2_005_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | social preference | sociality | time spent in social zone | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 482.7000000 | 92.8100000 | NA | NA | 21.87552679 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 675.1000000 | 85.5800000 | NA | NA | 20.17139944 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_006 | yang_2023_exp_003_assay_004 | yang_2023_exp2_006_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | social preference | sociality | time spent in social zone | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 482.7000000 | 92.8100000 | NA | NA | 21.87552679 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 495.1000000 | 96.2800000 | NA | NA | 22.69341363 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_004 | yang_2023_exp_001_assay_005 | yang_2023_exp2_004_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | time spent in social zone with familiar fish | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 348.0000000 | 89.6300000 | NA | NA | 21.1259936 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 312.1000000 | 61.5900000 | NA | NA | 14.51690222 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_005 | yang_2023_exp_002_assay_005 | yang_2023_exp2_005_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | time spent in social zone with familiar fish | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 348.0000000 | 89.6300000 | NA | NA | 21.1259936 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 444.6000000 | 111.1000000 | NA | NA | 26.18652113 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_006 | yang_2023_exp_003_assay_005 | yang_2023_exp2_006_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | time spent in social zone with familiar fish | time spent in social zone | zone | NA | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 348.0000000 | 89.6300000 | NA | NA | 21.1259936 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 475.4000000 | 88.0900000 | NA | NA | 20.76301212 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_004 | yang_2023_exp_001_assay_006 | yang_2023_exp2_004_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | distance to familiar fish | distance to conspecific | count | change | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 4.5200000 | 0.9100000 | NA | NA | 0.214489057 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 4.6200000 | 0.9800000 | NA | NA | 0.230988215 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_005 | yang_2023_exp_002_assay_006 | yang_2023_exp2_005_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | distance to familiar fish | distance to conspecific | count | change | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 4.5200000 | 0.9100000 | NA | NA | 0.214489057 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 3.2500000 | 1.0500000 | NA | NA | 0.247487373 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_006 | yang_2023_exp_003_assay_006 | yang_2023_exp2_006_assay_003 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | social recognition | sociality | distance to familiar fish | distance to conspecific | count | change | tables4 | yang_2023_tables4 | NA | NA | NA | 18 | 4.5200000 | 0.9100000 | NA | NA | 0.214489057 | study reports mean and sd | exact sample size provided | NA | NA | NA | 18 | 2.7200000 | 0.9700000 | NA | NA | 0.228631193 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_007 | yang_2023_exp_001_assay_007 | yang_2023_exp2_007_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | number of transition to the attack zone | frequency of entries into aggression zone | zone | NA | fig3g | yang_2023_tables4 | NA | NA | NA | 24 | 51.0000000 | 20.0000000 | NA | NA | 4.082482905 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 55.0000000 | 18.0000000 | NA | NA | 3.674234614 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_008 | yang_2023_exp_002_assay_007 | yang_2023_exp2_008_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | number of transition to the attack zone | frequency of entries into aggression zone | zone | NA | fig3g | yang_2023_tables4 | NA | NA | NA | 24 | 51.0000000 | 20.0000000 | NA | NA | 4.082482905 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 51.0000000 | 18.0000000 | NA | NA | 3.674234614 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_009 | yang_2023_exp_003_assay_007 | yang_2023_exp2_009_assay_001 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | number of transition to the attack zone | frequency of entries into aggression zone | zone | NA | fig3g | yang_2023_tables4 | NA | NA | NA | 24 | 51.0000000 | 20.0000000 | NA | NA | 4.082482905 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 70.0000000 | 28.0000000 | NA | NA | 5.715476066 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_001 | yang_2023_exp2_007 | yang_2023_exp_001_assay_008 | yang_2023_exp2_007_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 0.1 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | biting time | duration of aggressive behaviour | NA | NA | fig3h | yang_2023_tables4 | NA | NA | NA | 24 | 104.7000000 | 73.2100000 | NA | NA | 14.94392867 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 87.1400000 | 45.3300000 | NA | NA | 9.252947503 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_002 | yang_2023_exp2_008 | yang_2023_exp_002_assay_008 | yang_2023_exp2_008_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 10 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | biting time | duration of aggressive behaviour | NA | NA | fig3h | yang_2023_tables4 | NA | NA | NA | 24 | 104.7000000 | 73.2100000 | NA | NA | 14.94392867 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 82.6000000 | 59.2600000 | NA | NA | 12.09639685 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations | 10.1016/j.scitotenv.2022.159883 | https://www.sciencedirect.com/science/article/pii/S0048969722069832#:~:text=This%20result%20showed%20that%20THM,restlessness%20for%20adult%20male%20zebrafish. | Science of The Total Environment | yang_2023 | yang_2023_exp_003 | yang_2023_exp2_009 | yang_2023_exp_003_assay_008 | yang_2023_exp2_009_assay_002 | zebrafish | Danio rerio | commercial supplier | not_wild | male | thiamethoxam | commercial | 153719-23-4 | https://commonchemistry.cas.org/detail?cas_rn=153719-23-4&search=thiamethoxam | neonicotinoid | 1000 | ug/L | 45 | days | none | none | not reported | not reported | aggression | aggression | biting time | duration of aggressive behaviour | NA | NA | fig3h | yang_2023_tables4 | NA | NA | NA | 24 | 104.7000000 | 73.2100000 | NA | NA | 14.94392867 | study reports mean and sd | exact sample size provided | NA | NA | NA | 24 | 155.8000000 | 111.9000000 | NA | NA | 22.84149185 | study reports mean and sd | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_001 | zaluski_2022_exp2_001_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in aggression zone | zone | NA | fig7a | zaluski_2022_fig7a | NA | NA | NA | 18 | 191.1742446 | 65.0538239 | NA | NA | 15.33333333 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 230.6130256 | 58.5029846 | NA | NA | 13.78928571 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_001 | zaluski_2022_exp2_002_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 1 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in aggression zone | zone | NA | fig7a | zaluski_2022_fig7a | NA | NA | NA | 18 | 191.1742446 | 65.0538239 | NA | NA | 15.33333333 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 228.8290159 | 59.4938649 | NA | NA | 14.02283845 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_001 | zaluski_2022_exp2_003_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in aggression zone | zone | NA | fig7a | zaluski_2022_fig7a | NA | NA | NA | 18 | 191.1742446 | 65.0538239 | NA | NA | 15.33333333 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 232.2568209 | 54.2055214 | NA | NA | 12.77636392 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_001 | zaluski_2022_exp2_004_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in aggression zone | zone | NA | fig7a | zaluski_2022_fig7a | NA | NA | NA | 18 | 191.1742446 | 65.0538239 | NA | NA | 15.33333333 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 226.4558090 | 68.0943830 | NA | NA | 16.05 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_001 | zaluski_2022_exp2_005_assay2_001 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in aggression zone | zone | NA | fig7a | zaluski_2022_fig7a | NA | NA | NA | 18 | 191.1742446 | 65.0538239 | NA | NA | 15.33333333 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 209.3558090 | 72.5491558 | NA | NA | 17.1 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_002 | zaluski_2022_exp2_001_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7b | zaluski_2022_fig7b | NA | NA | NA | 18 | 238.1687637 | 81.6973497 | NA | NA | 19.25625 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 252.6040943 | 62.2554488 | NA | NA | 14.67375 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_002 | zaluski_2022_exp2_002_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 1 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7b | zaluski_2022_fig7b | NA | NA | NA | 18 | 238.1687637 | 81.6973497 | NA | NA | 19.25625 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 255.7298922 | 67.5889318 | NA | NA | 15.93086401 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_002 | zaluski_2022_exp2_003_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7b | zaluski_2022_fig7b | NA | NA | NA | 18 | 238.1687637 | 81.6973497 | NA | NA | 19.25625 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 253.6647802 | 41.3043472 | NA | NA | 9.735528004 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_002 | zaluski_2022_exp2_004_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7b | zaluski_2022_fig7b | NA | NA | NA | 18 | 238.1687637 | 81.6973497 | NA | NA | 19.25625 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 270.4806922 | 46.3109348 | NA | NA | 10.915592 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_002 | zaluski_2022_exp2_005_assay2_002 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7b | zaluski_2022_fig7b | NA | NA | NA | 18 | 238.1687637 | 81.6973497 | NA | NA | 19.25625 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 258.9750682 | 56.3241098 | NA | NA | 13.27572001 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_003 | zaluski_2022_exp2_001_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7e | zaluski_2022_fig7e | NA | NA | NA | 18 | 121.2528529 | 88.9421300 | NA | NA | 20.9638611 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 112.9625963 | 86.9447732 | NA | NA | 20.49307958 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_003 | zaluski_2022_exp2_002_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 1 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7e | zaluski_2022_fig7e | NA | NA | NA | 18 | 121.2528529 | 88.9421300 | NA | NA | 20.9638611 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 94.4191107 | 55.7370682 | NA | NA | 13.13735295 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_003 | zaluski_2022_exp2_003_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7e | zaluski_2022_fig7e | NA | NA | NA | 18 | 121.2528529 | 88.9421300 | NA | NA | 20.9638611 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 96.9347741 | 72.3395991 | NA | NA | 17.05060703 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_003 | zaluski_2022_exp2_004_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7e | zaluski_2022_fig7e | NA | NA | NA | 18 | 121.2528529 | 88.9421300 | NA | NA | 20.9638611 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 97.2142922 | 43.8781175 | NA | NA | 10.34217147 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_003 | zaluski_2022_exp2_005_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | atrazine | commercial | 1912-24-9 | https://commonchemistry.cas.org/detail?cas_rn=1912-24-9&search=atrazine | triazine | 5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7e | zaluski_2022_fig7e | NA | NA | NA | 18 | 121.2528529 | 88.9421300 | NA | NA | 20.9638611 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 65.9082597 | 50.9934879 | NA | NA | 12.01928036 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_004 | zaluski_2022_exp2_001_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7c | zaluski_2022_fig7c | NA | NA | NA | 18 | 63.5261868 | 59.0181751 | NA | NA | 13.91071727 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 76.1722934 | 61.3175845 | NA | NA | 14.45269327 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_004 | zaluski_2022_exp2_002_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 1 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7c | zaluski_2022_fig7c | NA | NA | NA | 18 | 63.5261868 | 59.0181751 | NA | NA | 13.91071727 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 75.0883414 | 63.6169939 | NA | NA | 14.99466926 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_004 | zaluski_2022_exp2_003_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7c | zaluski_2022_fig7c | NA | NA | NA | 18 | 63.5261868 | 59.0181751 | NA | NA | 13.91071727 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 77.6175628 | 52.8864166 | NA | NA | 12.46544794 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_004 | zaluski_2022_exp2_004_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7c | zaluski_2022_fig7c | NA | NA | NA | 18 | 63.5261868 | 59.0181751 | NA | NA | 13.91071727 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 113.1954355 | 64.1601215 | NA | NA | 15.12268567 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_004 | zaluski_2022_exp2_005_assay2_003 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7c | zaluski_2022_fig7c | NA | NA | NA | 18 | 63.5261868 | 59.0181751 | NA | NA | 13.91071727 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 99.5850184 | 72.1801367 | NA | NA | 17.01302138 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_005 | zaluski_2022_exp2_001_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7d | zaluski_2022_fig7d | NA | NA | NA | 18 | 1.6396186 | 2.6436709 | NA | NA | 0.623119213 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.2366158 | 3.1366815 | NA | NA | 0.739322917 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_005 | zaluski_2022_exp2_002_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 1 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7d | zaluski_2022_fig7d | NA | NA | NA | 18 | 1.6396186 | 2.6436709 | NA | NA | 0.623119213 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.4004179 | 4.0570252 | NA | NA | 0.95625 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_005 | zaluski_2022_exp2_003_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7d | zaluski_2022_fig7d | NA | NA | NA | 18 | 1.6396186 | 2.6436709 | NA | NA | 0.623119213 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 3.3457322 | 3.9111844 | NA | NA | 0.921875 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_005 | zaluski_2022_exp2_004_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7d | zaluski_2022_fig7d | NA | NA | NA | 18 | 1.6396186 | 2.6436709 | NA | NA | 0.623119213 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 3.0218627 | 3.9688823 | NA | NA | 0.935474537 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_005 | zaluski_2022_exp2_005_assay2_004 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 5 | mg/L | 96 | hours | none | none | 28 | celsius | aggression | aggression | number of bites | frequency of aggressive behaviour | count | NA | fig7d | zaluski_2022_fig7d | NA | NA | NA | 18 | 1.6396186 | 2.6436709 | NA | NA | 0.623119213 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.2284545 | 2.8697978 | NA | NA | 0.676417824 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp2_001 | zaluski_2022_exp_001_assay_006 | zaluski_2022_exp2_001_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 0.5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7f | zaluski_2022_fig7f | NA | NA | NA | 18 | 1.5801555 | 2.0427529 | NA | NA | 0.481481481 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 1.0767885 | 3.2188834 | NA | NA | 0.758698092 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp2_002 | zaluski_2022_exp_002_assay_006 | zaluski_2022_exp2_002_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 1 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7f | zaluski_2022_fig7f | NA | NA | NA | 18 | 1.5801555 | 2.0427529 | NA | NA | 0.481481481 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.5961782 | 4.3748958 | NA | NA | 1.03117284 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp2_003 | zaluski_2022_exp_003_assay_006 | zaluski_2022_exp2_003_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7f | zaluski_2022_fig7f | NA | NA | NA | 18 | 1.5801555 | 2.0427529 | NA | NA | 0.481481481 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.4637707 | 3.5067259 | NA | NA | 0.82654321 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp2_004 | zaluski_2022_exp_004_assay_006 | zaluski_2022_exp2_004_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 2.5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7f | zaluski_2022_fig7f | NA | NA | NA | 18 | 1.5801555 | 2.0427529 | NA | NA | 0.481481481 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 2.4646725 | 3.5079163 | NA | NA | 0.826823793 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | NA | KM | Atrazine and Diuron Effects on Survival, Embryo Development, and Behavior in Larvae and Adult Zebrafish | 10.3389/fphar.2022.841826 | https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.841826/full | Frontiers in<a0>Pharmacology | zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp2_005 | zaluski_2022_exp_005_assay_006 | zaluski_2022_exp2_005_assay2_005 | zebrafish | Danio rerio | laboratory stock from not specified source | not_wild | mixed | diuron | commercial | 330-54-1 | https://commonchemistry.cas.org/detail?cas_rn=330-54-1&search=diuron | urea | 5 | mg/L | 96 | hours | none | none | 28 | celsius | social interaction | sociality | time in stimulus zone close to mirror | time spent in social zone | zone | NA | fig7f | zaluski_2022_fig7f | NA | NA | NA | 18 | 1.5801555 | 2.0427529 | NA | NA | 0.481481481 | study reports mean and se | exact sample size provided | NA | NA | NA | 18 | 0.1847449 | 0.6333010 | NA | NA | 0.149270483 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp2_001 | zhou_2021_exp_001_assay_001 | zhou_2021_exp2_001_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | time spent on the side closest to the mirror | time spent in aggression zone | zone | NA | fig3e | zhou_2021_fig3e | NA | NA | NA | 22 | 108.2053673 | 76.4392733 | NA | NA | 16.29690783 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 93.3168342 | 35.8603998 | NA | NA | 7.645462935 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp2_002 | zhou_2021_exp_002_assay_001 | zhou_2021_exp2_002_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 50 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | time spent on the side closest to the mirror | time spent in aggression zone | zone | NA | fig3e | zhou_2021_fig3e | NA | NA | NA | 22 | 108.2053673 | 76.4392733 | NA | NA | 16.29690783 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 80.0378723 | 48.1284314 | NA | NA | 10.26101604 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp2_003 | zhou_2021_exp_003_assay_001 | zhou_2021_exp2_003_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 500 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | time spent on the side closest to the mirror | time spent in aggression zone | zone | NA | fig3e | zhou_2021_fig3e | NA | NA | NA | 22 | 108.2053673 | 76.4392733 | NA | NA | 16.29690783 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 68.9720707 | 14.1554210 | NA | NA | 3.017945895 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp2_004 | zhou_2021_exp_004_assay_001 | zhou_2021_exp2_004_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5000 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | time spent on the side closest to the mirror | time spent in aggression zone | zone | NA | fig3e | zhou_2021_fig3e | NA | NA | NA | 22 | 108.2053673 | 76.4392733 | NA | NA | 16.29690783 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 92.9144414 | 47.1847366 | NA | NA | 10.05981965 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp2_001 | zhou_2021_exp_001_assay_002 | zhou_2021_exp2_001_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | mirror biting frequency | frequency of aggressive behaviour | count | NA | fig3f | zhou_2021_fig3f | NA | NA | NA | 22 | 25.2365820 | 12.0032838 | NA | NA | 2.559108705 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 28.3344504 | 15.1620427 | NA | NA | 3.232558364 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp2_002 | zhou_2021_exp_002_assay_002 | zhou_2021_exp2_002_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 50 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | mirror biting frequency | frequency of aggressive behaviour | count | NA | fig3f | zhou_2021_fig3f | NA | NA | NA | 22 | 25.2365820 | 12.0032838 | NA | NA | 2.559108705 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 22.4080934 | 12.0032838 | NA | NA | 2.559108705 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp2_003 | zhou_2021_exp_003_assay_002 | zhou_2021_exp2_003_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 500 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | mirror biting frequency | frequency of aggressive behaviour | count | NA | fig3f | zhou_2021_fig3f | NA | NA | NA | 22 | 25.2365820 | 12.0032838 | NA | NA | 2.559108705 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 20.8816075 | 7.1598535 | NA | NA | 1.526485894 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp2_004 | zhou_2021_exp_004_assay_002 | zhou_2021_exp2_004_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5000 | ng/L | 105 | days | DMSO | solvent_used | 28 | celsius | aggression | aggression | mirror biting frequency | frequency of aggressive behaviour | count | NA | fig3f | zhou_2021_fig3f | NA | NA | NA | 22 | 25.2365820 | 12.0032838 | NA | NA | 2.559108705 | study reports mean and se | exact sample size provided | NA | NA | NA | 22 | 26.2692048 | 6.3175178 | NA | NA | 1.346899319 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp2_005 | zhou_2021_exp_001_assay_003 | zhou_2021_exp2_005_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5 | ng/L | 122 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | cluster score | group arrangment | NA | NA | fig5b | zhou_2021_fig5b | 9.428571 | 6.000000 | 22 | 6 | 2.5778057 | 1.6201614 | 0.8461017 | 1.6201614 | 0.34541958 | study reports mean and se | exact sample size provided | 9.428571 | 6.000000 | 22 | 6 | 3.0959351 | 2.3426659 | 1.2234174 | 2.3426659 | 0.499458042 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp2_006 | zhou_2021_exp_002_assay_003 | zhou_2021_exp2_006_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 50 | ng/L | 122 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | cluster score | group arrangment | NA | NA | fig5b | zhou_2021_fig5b | 9.428571 | 6.000000 | 22 | 6 | 2.5778057 | 1.6201614 | 0.8461017 | 1.6201614 | 0.34541958 | study reports mean and se | exact sample size provided | 9.428571 | 6.000000 | 22 | 6 | 2.4050959 | 0.5692459 | 0.2972790 | 0.5692459 | 0.121363636 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp2_007 | zhou_2021_exp_003_assay_003 | zhou_2021_exp2_007_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 500 | ng/L | 122 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | cluster score | group arrangment | NA | NA | fig5b | zhou_2021_fig5b | 9.428571 | 6.000000 | 22 | 6 | 2.5778057 | 1.6201614 | 0.8461017 | 1.6201614 | 0.34541958 | study reports mean and se | exact sample size provided | 9.428571 | 6.000000 | 22 | 6 | 1.9289770 | 1.1822800 | 0.6174256 | 1.1822800 | 0.252062937 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp2_008 | zhou_2021_exp_004_assay_003 | zhou_2021_exp2_008_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5000 | ng/L | 122 | days | DMSO | solvent_used | 28 | celsius | shoaling | collective behaviour | cluster score | group arrangment | NA | NA | fig5b | zhou_2021_fig5b | 9.428571 | 6.000000 | 22 | 6 | 2.5778057 | 1.6201614 | 0.8461017 | 1.6201614 | 0.34541958 | study reports mean and se | exact sample size provided | 9.428571 | 6.000000 | 22 | 6 | 1.5135400 | 1.0071274 | 0.5259551 | 1.0071274 | 0.21472028 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp2_009 | zhou_2021_exp_001_assay_004 | zhou_2021_exp2_009_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent on the side closest to the seperator | time spent in social zone | zone | NA | fig6b | zhou_2021_fig6b | NA | NA | NA | 20 | 167.4650762 | 67.9064632 | NA | NA | 15.18434677 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 160.4884845 | 64.2358435 | NA | NA | 14.36357127 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp2_010 | zhou_2021_exp_002_assay_004 | zhou_2021_exp2_010_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 50 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent on the side closest to the seperator | time spent in social zone | zone | NA | fig6b | zhou_2021_fig6b | NA | NA | NA | 20 | 167.4650762 | 67.9064632 | NA | NA | 15.18434677 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 144.2781683 | 55.0592945 | NA | NA | 12.31163252 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp2_011 | zhou_2021_exp_003_assay_004 | zhou_2021_exp2_011_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 500 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent on the side closest to the seperator | time spent in social zone | zone | NA | fig6b | zhou_2021_fig6b | NA | NA | NA | 20 | 167.4650762 | 67.9064632 | NA | NA | 15.18434677 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 124.3743624 | 57.8122592 | NA | NA | 12.92721415 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp2_012 | zhou_2021_exp_004_assay_004 | zhou_2021_exp2_012_assay2_001 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5000 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | time spent on the side closest to the seperator | time spent in social zone | zone | NA | fig6b | zhou_2021_fig6b | NA | NA | NA | 20 | 167.4650762 | 67.9064632 | NA | NA | 15.18434677 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 165.0027497 | 87.1772162 | NA | NA | 19.49341816 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp2_009 | zhou_2021_exp_001_assay_005 | zhou_2021_exp2_009_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | interaction frequency | frequency of social behaviour | count | NA | fig6c | zhou_2021_fig6c | NA | NA | NA | 20 | 28.5921715 | 5.5469371 | NA | NA | 1.240332846 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 39.0464055 | 12.1504337 | NA | NA | 2.716919568 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp2_010 | zhou_2021_exp_002_assay_005 | zhou_2021_exp2_010_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 50 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | interaction frequency | frequency of social behaviour | count | NA | fig6c | zhou_2021_fig6c | NA | NA | NA | 20 | 28.5921715 | 5.5469371 | NA | NA | 1.240332846 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 40.5229923 | 13.9994127 | NA | NA | 3.13036385 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp2_011 | zhou_2021_exp_003_assay_005 | zhou_2021_exp2_011_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 500 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | interaction frequency | frequency of social behaviour | count | NA | fig6c | zhou_2021_fig6c | NA | NA | NA | 20 | 28.5921715 | 5.5469371 | NA | NA | 1.240332846 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 33.3172491 | 10.8297344 | NA | NA | 2.421602224 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
| NA | NA | SN | KM | Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma) | 10.1016/j.aquatox.2021.105917 | https://www.sciencedirect.com/science/article/pii/S0166445X21001764?via%3Dihub | Aquatic Toxicology | zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp2_012 | zhou_2021_exp_004_assay_005 | zhou_2021_exp2_012_assay2_002 | marine medaka | Oryzias melastigma | laboratory stock from not specified source | not_wild | mixed | diuron | analytical | 330-54-1 | in paper | urea | 5000 | ng/L | 130 | days | DMSO | solvent_used | 28 | celsius | social interaction | sociality | interaction frequency | frequency of social behaviour | count | NA | fig6c | zhou_2021_fig6c | NA | NA | NA | 20 | 28.5921715 | 5.5469371 | NA | NA | 1.240332846 | study reports mean and se | exact sample size provided | NA | NA | NA | 20 | 30.4231391 | 10.3014546 | NA | NA | 2.303475286 | study reports mean and se | exact sample size provided | NA | NA | NA | NA |
# Summary of the data set
kable(summary(data), "html") %>%
kable_styling("bordered", position = "left") %>%
scroll_box(width = "250%", height = "500px")| comment_checker | comment_extractor | initials_checker | initials_extractor | title | doi | url | journal | study_id | exp_id | exp2_id | assay_id | assay2_id | species_english | species_latin | source | source2 | sex | pesticide | pesticide_grade | cas_id | cas_id_comment | pesticide_chemical_class | dosage | dosage_unit | duration | duration_unit | control_solvent | solvent2 | temperature | temperature_unit | behaviour_measured | behaviour_measured_standardised | behaviour_assay | behavioural_assay_standardised | behavioural_assay_standardised2 | effect_direction | data_source | data_file | control_effective_n | control_shoal_n | control_fish_n | control_n | control_mean | control_sd | control_shoal_sd | control_fish_sd | control_se | statistics_comment_control | sample_size_comment_control | treatment_effective_n | treatment_shoal_n | treatment_fish_n | treatment_n | treatment_mean | treatment_sd | treatment_shoal_sd | treatment_fish_sd | treatment_se | statistics_comment_treatment | sample_size_comment_treatment | contact_author | contacted_date | contact_response | contact_comments | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Length:461 | Mode:logical | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Length:461 | Min. : 1.600 | Min. : 1.00 | Min. : 4.00 | Min. : 2.00 | Min. : -0.20 | Min. : 0.0228 | Min. : 0.0359 | Min. : 0.1016 | Length:461 | Length:461 | Length:461 | Min. : 1.600 | Min. : 1.000 | Min. : 4.00 | Min. : 2.00 | Min. : 0.11 | Min. : 0.0185 | Min. : 0.0199 | Min. : 0.0563 | Length:461 | Length:461 | Length:461 | Mode:logical | Mode:logical | Mode:logical | Mode:logical | |
| Class :character | NA’s:461 | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | Class :character | 1st Qu.: 1.714 | 1st Qu.: 1.00 | 1st Qu.: 6.00 | 1st Qu.:15.00 | 1st Qu.: 6.31 | 1st Qu.: 2.6437 | 1st Qu.: 0.4760 | 1st Qu.: 0.9800 | Class :character | Class :character | Class :character | 1st Qu.: 1.714 | 1st Qu.: 1.000 | 1st Qu.: 6.00 | 1st Qu.:14.00 | 1st Qu.: 6.24 | 1st Qu.: 2.6824 | 1st Qu.: 0.3770 | 1st Qu.: 0.8731 | Class :character | Class :character | Class :character | NA’s:461 | NA’s:461 | NA’s:461 | NA’s:461 | |
| Mode :character | NA | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Mode :character | Median : 9.500 | Median : 6.00 | Median :19.00 | Median :18.00 | Median : 30.86 | Median : 25.2242 | Median : 1.5793 | Median : 3.3584 | Mode :character | Mode :character | Mode :character | Median : 8.500 | Median : 6.000 | Median : 23.00 | Median :18.00 | Median : 40.89 | Median : 24.9424 | Median : 1.0233 | Median : 2.0768 | Mode :character | Mode :character | Mode :character | NA | NA | NA | NA | |
| NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Mean : 9.084 | Mean : 18.35 | Mean :17.84 | Mean :20.35 | Mean : 138.09 | Mean : 43.0893 | Mean : 16.0316 | Mean : 40.7438 | NA | NA | NA | Mean : 8.036 | Mean : 5.523 | Mean : 29.89 | Mean :20.08 | Mean : 130.37 | Mean : 47.4361 | Mean : 11.6351 | Mean : 32.4113 | NA | NA | NA | NA | NA | NA | NA | |
| NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 3rd Qu.:15.000 | 3rd Qu.: 10.00 | 3rd Qu.:24.00 | 3rd Qu.:24.00 | 3rd Qu.: 144.69 | 3rd Qu.: 59.2010 | 3rd Qu.: 3.2719 | 3rd Qu.: 6.2733 | NA | NA | NA | 3rd Qu.:10.750 | 3rd Qu.: 8.000 | 3rd Qu.: 30.00 | 3rd Qu.:24.00 | 3rd Qu.: 137.55 | 3rd Qu.: 55.8427 | 3rd Qu.: 3.1970 | 3rd Qu.: 6.8992 | NA | NA | NA | NA | NA | NA | NA | |
| NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Max. :23.000 | Max. :128.00 | Max. :46.00 | Max. :72.00 | Max. :2013.65 | Max. :535.6481 | Max. :309.2566 | Max. :1014.5103 | NA | NA | NA | Max. :23.500 | Max. :15.667 | Max. :128.00 | Max. :72.00 | Max. :1847.54 | Max. :991.3481 | Max. :358.3868 | Max. :1433.5471 | NA | NA | NA | NA | NA | NA | NA | |
| NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA’s :366 | NA’s :366 | NA’s :366 | NA’s :4 | NA | NA’s :18 | NA’s :366 | NA’s :366 | NA | NA | NA | NA’s :366 | NA’s :366 | NA’s :366 | NA’s :8 | NA | NA’s :18 | NA’s :366 | NA’s :366 | NA | NA | NA | NA | NA | NA | NA |
Data exploration and reporting of methodological items
Figure 1b & 1c
- A bubble plot showing the number of effect sizes of each pesticide class per conspecific interaction behaviour described
- A bar chart showing the total number of effect sizes per species
# Summarize data by grouping on pesticide chemical class and behavior measured,
# then count entries.
pc_cb_summary <- data %>%
group_by(pesticide_chemical_class, behaviour_measured_standardised) %>%
summarise(n = n(), .groups = "drop")
# Determine the top 9 pesticide classes based on the number of records.
top_pesticide_class <- pc_cb_summary %>%
group_by(pesticide_chemical_class) %>%
summarise(total_count = sum(n)) %>%
top_n(9, total_count) %>%
pull(pesticide_chemical_class)
# Adjust category names to 'Other pesticide classes' for those pesticide
# classes not in the top 9
pc_cb_summary_filtered <- pc_cb_summary %>%
mutate(pesticide_chemical_class = ifelse(pesticide_chemical_class %in% top_pesticide_class,
pesticide_chemical_class, "Other Pesticide Classes")) %>%
group_by(pesticide_chemical_class, behaviour_measured_standardised) %>%
summarise(n = sum(n), .groups = "drop")
# Create the bubble plot
behaviour_pesticide_class_bubble_plot <- pc_cb_summary_filtered %>%
ggplot(aes(x = fct_rev(fct_reorder(str_to_title(behaviour_measured_standardised),
n, .fun = "sum")), y = fct_reorder(str_to_title(pesticide_chemical_class),
n, .fun = "sum"), size = n)) + geom_point(alpha = 0.5, color = RColorBrewer::brewer.pal(n = 8,
name = "Dark2")[3]) + scale_size_continuous(range = c(5, 20)) + theme_bw() +
guides(size = "none") + theme(legend.position = "none", axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"), plot.caption = element_text(size = 10,
color = "gray10", face = "italic")) + geom_text(aes(label = as.character(n)),
size = 4, color = "gray10") + labs(caption = "The value in each cell is the total number of effect sizes",
x = "Behaviour Measured", y = "Pesticide Chemical Class", tag = "B")
# Group data by species, count entries, and drop groups post-summary.
sp_summary <- data %>%
group_by(species_english) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportion and percentage of total counts for each species.
species_pct <- sp_summary %>%
mutate(proportion = n/sum(n), percentage = proportion * 100)
# Create the bar plot
species_effect_size_count_bar_plot <- sp_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(species_english), n))) + geom_bar(stat = "identity",
width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[2]) +
geom_text(aes(label = ifelse(n < 9, "", n), x = n/2, y = reorder(str_to_title(species_english),
n)), hjust = 0.5, size = 4, color = "black") + geom_text(data = species_pct,
aes(label = paste0("(", round(percentage, 1), "%)"), x = n), hjust = -0.1, size = 4,
color = "black", fontface = "bold") + scale_x_continuous(expand = c(0, 0), limits = c(0,
max(sp_summary$n) * 1.2)) + theme_bw() + guides(size = "none") + theme(legend.position = "none",
axis.text = element_text(color = "black"), axis.title = element_text(face = "bold",
color = "black"), plot.caption = element_text(size = 10, color = "gray10",
face = "italic")) + labs(caption = "The value in each bar is the total number of effect sizes",
x = "Total number of effect size estimates", y = "Species", tag = "C")
# Combine both plots into a single figure.
main_text_figure_1 <- behaviour_pesticide_class_bubble_plot/species_effect_size_count_bar_plot
print(main_text_figure_1)
Figure sx
A bubble plot showing the number of effect sizes of each species per conspecific interaction behaviour described
# Group data by species, count entries, and drop groups post-summary.
species_summary <- data %>%
group_by(species_english, behaviour_measured_standardised) %>%
summarise(
n = n(),
pesticide_chemical_class = first(pesticide_chemical_class),
.groups = "drop"
)
# Determine the top 20 species based on the number of records.
top_species <- species_summary %>%
group_by(species_english, behaviour_measured_standardised) %>%
summarise(total_count = sum(n), .groups = "drop") %>%
top_n(20, total_count) %>%
pull(species_english)
# Adjust category names to 'Other' for all but the top species, then re-summarize.
# species_summary_filtered <- species_summary %>%
# mutate(species_english = ifelse(species_english %in% top_species,
# species_english,
# "Other Species")) %>%
# group_by(species_english, behaviour_measured_standardised) %>%
# summarise(n = sum(n), .groups = "drop")
# Create the bubble plot the behaviours assessed per species (number of effect size as count)
behaviour_species_bubble_plot <- species_summary %>% # can add _filtered if needed
ggplot(aes(x = fct_rev(fct_reorder(str_to_title(behaviour_measured_standardised), n, .fun = 'sum')),
y = fct_reorder(str_to_title(species_english), n, .fun = 'sum'),
size = n)) +
geom_point(alpha = 0.5, color = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[2]) +
scale_size_continuous(range = c(8, 25)) +
theme_bw() +
guides(size = "none") +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
geom_text(aes(label = as.character(n)), size = 4, color = "gray10") +
labs(caption = "The value in each cell is the number of effect sizes",
x = "Behaviour Measured",
y = "Species") +
scale_color_brewer(palette = "Dark2", name = "Chemical Class")
print(behaviour_species_bubble_plot)
Figure sx
A bar chart showing the sex of fish used in the literature
# Group data by 'sex of fish' and count entries, then drop grouping for further
# analysis.
sex_summary <- data %>%
group_by(sex) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportions and percentages of total studies for each sex.
sex_pct <- sex_summary %>%
mutate(proportion = n/sum(n), percentage = proportion * 100)
# Create a bar plot visualizing the number of studies per sex, with annotations
# for counts and percentages.
fish_sex_study_count_bar_plot <- sex_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(sex), n))) + geom_bar(stat = "identity",
width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[2]) +
geom_text(aes(label = n, x = n/2, y = reorder(str_to_title(sex), n)), hjust = 0.5,
size = 4, color = "black") + geom_text(data = sex_pct, aes(label = paste0("(",
round(percentage, 1), "%)"), x = n), hjust = -0.1, size = 4, color = "black",
fontface = "bold") + scale_x_continuous(expand = c(0, 0), limits = c(0, max(sex_summary$n) *
1.2)) + theme_bw() + guides(size = "none") + theme(legend.position = "none",
axis.text = element_text(color = "black"), axis.title = element_text(face = "bold",
color = "black"), plot.caption = element_text(size = 10, color = "gray10",
face = "italic")) + labs(caption = "The value in each bar is the total number of studies",
x = "Total number of effect sizes", y = "Sex of fish")
print(fish_sex_study_count_bar_plot)
Figure sx
A bar chart showing the reporting of the source of fish used in the literature
# Extracts unique records from the dataset based on 'study_id', retaining all other associated data.
data_study <- data %>%
distinct(study_id, .keep_all = TRUE)
# Groups the filtered data by 'source of fish' and counts the number of studies per source, removing grouping afterwards.
source_summary <- data %>%
group_by(source) %>%
summarise(n = n(), .groups = "drop")
# Calculates the proportion and percentage of total studies for each source of fish.
source_pct <- source_summary %>%
mutate(proportion = n / sum(n), # number of studies
percentage = proportion * 100)
# Create the bar plot for the source of fish study count
fish_source_study_count_bar_plot <- source_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(source), n))) +
geom_bar(stat = "identity", width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[1]) +
geom_text(aes(label = n, x = n / 2, y = reorder(str_to_title(source), n)), hjust = 0.5, size = 4, color = "black") +
geom_text(data = source_pct, aes(label = paste0("(", round(percentage, 1), "%)"), x = n),
hjust = -0.1, size = 4, color = "black", fontface = "bold") +
scale_x_continuous(expand = c(0, 0), limits = c(0, max(source_summary$n) * 1.2)) +
theme_bw() +
guides(size = "none") +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
labs(caption = "The value in each bar is the total number of studies",
x = "Total number of studies",
y = "Source of fish")
print(fish_source_study_count_bar_plot)
Figure sx
A bubble plot showing the number of effect sizes of each pesticide per conspecific interaction behaviour described
# Group data by species, count entries, and drop groups post-summary.
p_cb_summary <- data %>%
group_by(pesticide, behaviour_measured_standardised) %>%
summarise(
n = n(),
pesticide_chemical_class = first(pesticide_chemical_class),
.groups = "drop"
)
# Determine the top 8 pesticide classes based on the number of records.
top_pesticides <- p_cb_summary %>%
group_by(pesticide, behaviour_measured_standardised) %>%
summarise(total_count = sum(n), .groups = "drop") %>%
top_n(20, total_count) %>%
pull(pesticide)
# Adjust category names to 'Other Pesticides' for all but the top pesticide, then re-summarize.
# p_cb_summary_filtered <- p_cb_summary %>%
# mutate(pesticide = ifelse(pesticide %in% top_pesticides,
# pesticide,
# "Other Pesticides")) %>%
# group_by(pesticide, behaviour_measured_standardised) %>%
# summarise(n = sum(n), .groups = "drop")
# Create the bubble plot for the behaviours assessed per pesticide (effect size as count)
behaviour_pesticide_bubble_plot <- p_cb_summary %>% # can add _filtered if needed
ggplot(aes(x = fct_rev(fct_reorder(str_to_title(behaviour_measured_standardised), n, .fun = 'sum')),
y = fct_reorder(str_to_title(pesticide), n, .fun = 'sum'),
size = n)) +
geom_point(alpha = 0.5, color = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[5]) +
scale_size_continuous(range = c(4, 20)) +
theme_bw() +
guides(size = "none") +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
geom_text(aes(label = as.character(n)), size = 4, color = "gray10") +
labs(caption = "The value in each cell is the number of effect sizes",
x = "Behaviour Measured",
y = "Pesticide Chemical Class") +
scale_y_discrete(labels = function(x) ifelse(x %in% c("Ddt", "Dca", "Dcpmu"), toupper(x), x))
print(behaviour_pesticide_bubble_plot)
Figure sx
A bar plot showing the control solvents used in the literature
# Group data by 'control solvent' and count entries, then drop the group
# structure for further analysis.
solvent_summary <- data %>%
group_by(control_solvent) %>%
summarise(n = n(), .groups = "drop")
# Calculate the proportion and percentage of total studies for each control
# solvent.
solvent_pct <- solvent_summary %>%
mutate(proportion = n/sum(n), percentage = proportion * 100)
# Create a bar plot visualizing the number of studies per control solvent,
# annotated with counts and percentages.
control_solvent_study_count_bar_plot <- solvent_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(control_solvent), n))) + geom_bar(stat = "identity",
width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[3]) +
geom_text(aes(label = n, x = n/2, y = reorder(str_to_title(control_solvent),
n)), hjust = 0.5, size = 4, color = "black") + geom_text(data = solvent_pct,
aes(label = paste0("(", round(percentage, 1), "%)"), x = n), hjust = -0.1, size = 4,
color = "black", fontface = "bold") + scale_x_continuous(expand = c(0, 0), limits = c(0,
max(solvent_summary$n) * 1.3)) + theme_bw() + guides(size = "none") + theme(legend.position = "none",
axis.text = element_text(color = "black"), axis.title = element_text(face = "bold",
color = "black"), plot.caption = element_text(size = 10, color = "gray10",
face = "italic")) + labs(caption = "The value in each bar is the total number of studies",
x = "Total number of studies", y = "Control Solvent") + scale_y_discrete(labels = function(x) ifelse(x ==
"Dmso", toupper(x), ifelse(x == "Dtnb", toupper(x), x)))
print(control_solvent_study_count_bar_plot)
Figure sx
A box and violin plot showing the distribution of pesticide dosages used in the literature
# making dosages consistent for dosage comparisons
data_dosage <- data %>%
filter(dosage != "not reported") %>%
filter(dosage_unit != "not reported") %>%
filter(!dosage_unit %in% c("nm", "um", "nM")) %>%
mutate(dosage = as.numeric(dosage), dosage_unit = as.character(dosage_unit),
dosage_unit_consistent = case_when(dosage_unit == "mg/L" ~ "ug/L", dosage_unit ==
"ng/L" ~ "ug/L", dosage_unit == "g/L" ~ "ug/L", dosage_unit == "ppb" ~
"ug/L", dosage_unit == "ppm" ~ "ug/L", TRUE ~ dosage_unit), dosage_convert_ugL = case_when(dosage_unit ==
"mg/L" ~ dosage * 1000, dosage_unit == "ng/L" ~ dosage/1000, dosage_unit ==
"g/L" ~ dosage/1e+06, dosage_unit == "ppm" ~ dosage * 1000, TRUE ~ dosage))
# Summary table for the dosage converted
summary_data_dosage <- summary(data_dosage$dosage_convert_ugL)
# Filter the data for dosage_convert_ugL less than 5000
filtered_data_dosage <- data_dosage %>%
filter(dosage_convert_ugL < 3000)
# Create the violin plot
pesticide_dosage_violin_plot <- ggplot(filtered_data_dosage, aes(y = dosage_unit_consistent,
x = dosage_convert_ugL)) + geom_violin(fill = RColorBrewer::brewer.pal(n = 8,
name = "Set2")[1], alpha = 0.4, color = NA, trim = FALSE) + geom_boxplot(width = 0.1,
fill = "white", color = RColorBrewer::brewer.pal(n = 8, name = "Set2")[2], outlier.shape = NA) +
geom_jitter(width = 0.3, height = 0.09, color = RColorBrewer::brewer.pal(n = 8,
name = "Set2")[1], alpha = 0.8) + theme_bw() + theme(legend.position = "none",
plot.title = element_text(face = "bold", hjust = 0.5), axis.title.x = element_blank(),
axis.title.y = element_text(face = "bold"), axis.text.x = element_text(color = "black"),
axis.text.y = element_blank(), axis.ticks = element_line(color = "black"), plot.caption = element_text(size = 10,
color = "gray10", face = "italic")) + labs(caption = "Plot filtered for less than 3000 ug/L\nMedian = 12, 1st Quartile = 1, 3rd Quartile = 500",
y = "Dosage Unit [ug/L]")
print(pesticide_dosage_violin_plot)
# ggsave(here('figures', 'pesticide_dosage_violin_plot.pdf'), plot =
# dosage_violin_plot, width = 10, height = 5, units = 'cm', scale = 2, dpi =
# 800) ggsave(here('figures', 'pesticide_dosage_violin_plot.jpg'), plot =
# dosage_violin_plot, width = 10, height = 5, units = 'cm', scale = 2, dpi =
# 800)Figure sx
A box and violin plot the distribution of durations of pesticide exposure
data_duration <- data %>%
filter(!is.na(duration), duration != "not reported") %>%
mutate(duration = as.numeric(duration), duration_unit = as.character(duration_unit),
duration_unit_consistent = case_when(duration_unit == "minutes" ~ "hours",
duration_unit == "days" ~ "hours", duration_unit == "weeks" ~ "hours",
TRUE ~ duration_unit), duration_convert = case_when(duration_unit ==
"minutes" ~ duration/60, duration_unit == "days" ~ duration * 24, duration_unit ==
"weeks" ~ duration * 168, TRUE ~ duration))
summary(data_duration$duration_convert)## Min. 1st Qu. Median Mean 3rd Qu. Max.
## 2.0 96.0 336.0 651.6 960.0 3120.0# Create the violin plot for duration
pesticide_duration_violin_plot <- ggplot(data_duration, aes(y = duration_unit_consistent,
x = duration_convert)) + geom_violin(fill = RColorBrewer::brewer.pal(n = 8, name = "Set2")[1],
alpha = 0.4, color = NA, trim = FALSE) + geom_boxplot(width = 0.1, fill = "white",
color = RColorBrewer::brewer.pal(n = 8, name = "Set2")[2], outlier.shape = NA) +
geom_jitter(width = 0.3, height = 0.09, color = RColorBrewer::brewer.pal(n = 8,
name = "Set2")[1], alpha = 0.8) + theme_bw() + theme(legend.position = "none",
plot.title = element_text(face = "bold", hjust = 0.5), axis.title.x = element_blank(),
axis.title.y = element_text(face = "bold"), axis.text.x = element_text(color = "black"),
axis.text.y = element_blank(), axis.ticks = element_line(color = "black"), plot.caption = element_text(size = 10,
color = "gray10", face = "italic")) + labs(caption = "Median = 336, 1st Quartile = 96, 3rd Quartile = 960",
y = "Duration [hours]")
print(pesticide_duration_violin_plot)
# ggsave(here('figures', 'pesticide_duration_violin_plot.pdf'), plot =
# dosage_violin_plot, width = 10, height = 5, units = 'cm', scale = 2, dpi =
# 800) ggsave(here('figures', 'pesticide_duration_violin_plot.jpg'), plot =
# dosage_violin_plot, width = 10, height = 5, units = 'cm', scale = 2, dpi =
# 800)Figure sx
A bar plot showing the behavioural assays used to quantify soliality in the literature
# Filter data for entries containing 'sociality' in
# behaviour_measure_standardised
sociality_data <- data %>%
filter(grepl("sociality", behaviour_measured_standardised, ignore.case = TRUE))
# Group data by behavioural_assay_standardized and count occurrences
sociality_assay_summary <- sociality_data %>%
group_by(behavioural_assay_standardised) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportion of effect sizes for each control solvent
sociality_assay_pct <- sociality_assay_summary %>%
mutate(proportion = n/sum(n), percentage = proportion * 100)
# Create a bar plot visualizing the number of studies quantifying pesticide
# impacts on aggression, annotated with counts and percentages.
sociality_assay_effect_size_count_bar_plot <- sociality_assay_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(behavioural_assay_standardised), n))) +
geom_bar(stat = "identity", width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8,
name = "Dark2")[5]) + geom_text(aes(label = ifelse(n < 0, "", n), x = n/2,
y = reorder(str_to_title(behavioural_assay_standardised), n)), hjust = 0.5, size = 4,
color = "black") + geom_text(data = sociality_assay_pct, aes(label = paste0("(",
round(percentage, 1), "%)"), x = n), hjust = -0.1, size = 4, color = "black",
fontface = "bold") + scale_x_continuous(expand = c(0, 0), limits = c(0, max(sociality_assay_summary$n) *
1.3)) + theme_bw() + guides(size = "none") + theme(legend.position = "none",
axis.text = element_text(color = "black"), axis.title = element_text(face = "bold",
color = "black"), plot.caption = element_text(size = 10, color = "gray10",
face = "italic")) + labs(caption = "The value in each bar is the total number of effect sizes",
x = "Total Number of Effect Sizes", y = "Sociality Assay")
print(sociality_assay_effect_size_count_bar_plot)
Figure sx
A bar plot showing the behavioural assays used to quantify aggression in the literature
# Filter data for entries containing 'aggression' in
# behaviour_measure_standardised
aggression_data <- data %>%
filter(grepl("aggression", behaviour_measured_standardised, ignore.case = TRUE))
# Group data by behavioural_assay_standardised and count occurrences
aggression_assay_summary <- aggression_data %>%
group_by(behavioural_assay_standardised) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportion of effect sizes for each behavioural assay
aggression_assay_pct <- aggression_assay_summary %>%
mutate(proportion = n/sum(n), percentage = proportion * 100)
# Create a bar plot visualizing the number of studies quantifying pesticide
# impacts on aggression, annotated with counts and percentages.
aggression_assay_effect_size_count_bar_plot <- aggression_assay_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(behavioural_assay_standardised), n))) +
geom_bar(stat = "identity", width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8,
name = "Dark2")[6]) + geom_text(aes(label = ifelse(n < 0, "", n), x = n/2,
y = reorder(str_to_title(behavioural_assay_standardised), n)), hjust = 0.5, size = 4,
color = "black") + geom_text(data = aggression_assay_pct, aes(label = paste0("(",
round(percentage, 1), "%)"), x = n), hjust = -0.1, size = 4, color = "black",
fontface = "bold") + scale_x_continuous(expand = c(0, 0), limits = c(0, max(aggression_assay_summary$n) *
1.3)) + theme_bw() + guides(size = "none") + theme(legend.position = "none",
axis.text = element_text(color = "black"), axis.title = element_text(face = "bold",
color = "black"), plot.caption = element_text(size = 10, color = "gray10",
face = "italic")) + labs(caption = "The value in each bar is the total number of effect sizes",
x = "Total Number of Effect Sizes", y = "Aggression Assay")
print(aggression_assay_effect_size_count_bar_plot)
Figure sx
A bar plot showing the behavioural assays used to quantify courtship in the literature
# Filter data for entries containing "courtship" in behaviour_measure_standardised
courtship_data <- data %>%
filter(grepl("courtship", behaviour_measured_standardised, ignore.case = TRUE))
# Group data by behavioural_assay_standardised and count occurrences
courtship_assay_summary <- courtship_data %>%
group_by(behavioural_assay_standardised) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportion of effect sizes for each behavioural assay
courtship_assay_pct <- courtship_assay_summary %>%
mutate(proportion = n / sum(n), # Adjust total number of observations
percentage = proportion * 100)
# Create a bar plot visualizing the number of studies quantifying pesticide impacts on courtship, annotated with counts and percentages.
courtship_assay_effect_size_count_bar_plot <- courtship_assay_summary %>%
ggplot(aes(x = n, y = reorder(str_to_title(behavioural_assay_standardised), n))) +
geom_bar(stat = "identity", width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[6]) +
geom_text(aes(label = ifelse(n < 0, "", n), x = n / 2, y = reorder(str_to_title(behavioural_assay_standardised), n)),
hjust = 0.5, size = 4, color = "black") +
geom_text(data = courtship_assay_pct, aes(label = paste0("(", round(percentage, 1), "%)"), x = n),
hjust = -0.1, size = 4, color = "black", fontface = "bold") +
scale_x_continuous(expand = c(0, 0), limits = c(0, max(courtship_assay_summary$n) * 1.3)) +
theme_bw() +
guides(size = "none") +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
labs(caption = "The value in each bar is the total number of effect sizes",
x = "Total Number of Effect Sizes",
y = "Courtship Assay")
print(courtship_assay_effect_size_count_bar_plot)
Figure sx
A bar plot showing the behavioural assays used to quantify collective behaviour (i.e., behaviours measure at collective level) in the literature
# Filter data for entries containing "collective behaviour" in behaviour_measure_standardised
collective_behaviour_data <- data %>%
filter(grepl("collective behaviour", behaviour_measured_standardised, ignore.case = TRUE))
# Group data by behavioural_assay_standardised and count occurrences
collective_behaviour_assay_summary <- collective_behaviour_data %>%
group_by(behavioural_assay_standardised) %>%
summarise(n = n(), .groups = "drop")
# Calculate proportion of effect sizes for each behavioural assay
collective_behaviour_assay_pct <- collective_behaviour_assay_summary %>%
mutate(proportion = n / sum(n), # Adjust total number of observations
percentage = proportion * 100)
# Create a bar plot visualizing the number of studies quantifying pesticide impacts on collective behaviour, annotated with counts and percentages.
collective_behaviour_assay_effect_size_count_bar_plot <- collective_behaviour_assay_summary %>%
ggplot(aes(x = n, y = reorder(str_to_sentence(behavioural_assay_standardised), n))) +
geom_bar(stat = "identity", width = 0.8, alpha = 0.5, fill = RColorBrewer::brewer.pal(n = 8, name = "Dark2")[7]) +
geom_text(aes(label = ifelse(n < 9, "", n), x = n / 2, y = reorder(str_to_sentence(behavioural_assay_standardised), n)),
hjust = 0.5, size = 4, color = "black") +
geom_text(data = collective_behaviour_assay_pct, aes(label = paste0("(", round(percentage, 1), "%)"), x = n),
hjust = -0.1, size = 4, color = "black", fontface = "bold") +
scale_x_continuous(expand = c(0, 0), limits = c(0, max(collective_behaviour_assay_summary$n) * 1.3)) +
theme_bw() +
guides(size = "none") +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
labs(caption = "The value in each bar is the total number of effect sizes",
x = "Total Number of Effect Sizes",
y = "Collective Behaviour Assay")
print(collective_behaviour_assay_effect_size_count_bar_plot)
Figure sx
A sankey diagram showing the relationship between variables
# Select relevant columns and replace NA values with 'Not Reported'
data_sankey <- data %>%
select(c(behaviour_measured_standardised, behavioural_assay_standardised2, pesticide_chemical_class,
control_solvent, species_english, sex, source)) %>%
mutate(across(c(behaviour_measured_standardised, behavioural_assay_standardised2,
pesticide_chemical_class, control_solvent, species_english, sex, source),
~replace_na(., "Not Reported")))
# Transform data into a long format for the Sankey plot
sankey_df <- data_sankey %>%
ggsankey::make_long(behaviour_measured_standardised, behavioural_assay_standardised2,
pesticide_chemical_class, control_solvent, species_english, sex, source)
# Create the Sankey plot
ggplot(sankey_df, aes(x = x, next_x = next_x, node = node, next_node = next_node,
fill = factor(node), label = node)) + geom_sankey(flow.alpha = 0.6, node.color = "gray30") +
geom_sankey_label(size = 3, color = "white", fill = "gray40") + scale_fill_viridis_d() +
scale_x_discrete(labels = c("Behaviour Measured", "Assay type", "Pesticide chemical class",
"Control Solvent", "Species", "Sex", "Source"), position = "top") + theme_sankey(base_size = 10) +
labs(x = NULL) + theme(legend.position = "none", plot.title = element_text(hjust = 0.5),
axis.text.x = element_text(color = "black", size = 9))
Calculate effect size estimates & dependency
Find SD/Mean ratio
A bar plot showing the SD/Mean ratio of the control and treatment groups in each primary study
sd_mean_ratio <- data %>%
mutate(control_sd = as.numeric(control_sd), treatment_sd = as.numeric(treatment_sd)) %>%
group_by(study_id) %>%
mutate(within_study_control_mean = mean(control_mean, na.rm = TRUE), within_study_treatment_mean = mean(treatment_mean,
na.rm = TRUE), within_study_control_sd = mean(control_sd, na.rm = TRUE),
within_study_treatment_sd = mean(treatment_sd, na.rm = TRUE), sd_mean_ratio_control = within_study_control_sd/within_study_control_mean,
sd_mean_ratio_treatment = within_study_treatment_sd/within_study_treatment_mean)
sd_mean_ratio_bar_plot <- sd_mean_ratio %>%
ggplot() + geom_histogram(aes(x = sd_mean_ratio_control), fill = "blue", alpha = 0.4) +
geom_histogram(aes(x = sd_mean_ratio_treatment), fill = "red", alpha = 0.4) +
scale_x_continuous(expand = c(0, 0)) + scale_y_continuous(expand = c(0, 0)) +
theme_bw() + guides(size = "none") + theme(legend.position = "none", axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"), plot.caption = element_text(size = 10,
color = "gray10", face = "italic")) + labs(caption = "Red = Control, Blue = Treatment, Purple = Both\nThe value in each bar is the total number of effect sizes",
x = "SD/Mean Ratio", y = "Frequency")
print(sd_mean_ratio_bar_plot)
Impute missing standard deviations & plot
We imputed the missing standard deviations using the formula provided in section 13.1 (p. 199) of the Handbook of Meta-analysis in Ecology and Evolution (Koricheva, Gurevitch, and Mengersen, 2013).
To ensure consistency in treatments subjected to repeated stepwise multiple comparisons (i.e., the same data used multiple times to calculate different effect sizes), we maintained the same imputed standard deviations (or standard errors) for the repeated data.
# Indicate which individuals are used in more than one control or treatment to
# calculate sampling variances of non-independent observations differently.
data_shared_indiv <- group_by(data, exp_id) %>%
summarise(number_treatment = n())
data <- left_join(data, data_shared_indiv, by = "exp_id")
# Calculate the within and between study impacts of pesticides on fish social
# behaviour
data <- data %>%
group_by(study_id) %>%
mutate(control_sd = as.numeric(control_sd), treatment_sd = as.numeric(treatment_sd)) %>%
group_by(study_id) %>%
mutate(within_study_control_mean = mean(control_mean, na.rm = TRUE), within_study_treatment_mean = mean(treatment_mean,
na.rm = TRUE), within_study_control_sd = mean(control_sd, na.rm = TRUE),
within_study_treatment_sd = mean(treatment_sd, na.rm = TRUE), sd_mean_ratio_control = within_study_control_sd/within_study_control_mean,
sd_mean_ratio_treatment = within_study_treatment_sd/within_study_treatment_mean) %>%
ungroup() %>%
mutate(between_study_control_mean = mean(within_study_control_mean, na.rm = T),
between_study_treatment_mean = mean(within_study_treatment_mean, na.rm = T),
between_study_control_sd = mean(within_study_control_sd, na.rm = T), between_study_treatment_sd = mean(within_study_treatment_sd,
na.rm = T))
# label missing location
data$control_sd_report <- ifelse(is.na(data$control_sd), "Yes", "No")
data$treatment_sd_report <- ifelse(is.na(data$treatment_sd), "Yes", "No")
data %>%
select(control_sd, treatment_sd) %>%
impute_missingness() # Missing SD == 3.9%, 36 imputations needed ##
## Summary of missingness:
##
## COLUMN PERCENT_MISSINGNESS IMPUTATIONS
## control_sd 3.9 18
## treatment_sd 3.9 18
##
## Total missingness: 3.9% (36 imputations needed)## COLUMN PERCENT_MISSINGNESS IMPUTATIONS
## control_sd control_sd 3.904555 18
## treatment_sd treatment_sd 3.904555 18data <- as.data.frame(data) # convert into dataframe
data <- impute_SD(data, columnSDnames = c("control_sd", "treatment_sd"), columnXnames = c("control_mean",
"treatment_mean"), method = "Bracken1992")
# Convert sd columns to log10 and create a combined dataframe for plotting
data_long <- data %>%
mutate(log_control_sd = log10(control_sd), log_treatment_sd = log10(treatment_sd)) %>%
pivot_longer(cols = c(log_control_sd, log_treatment_sd), names_to = "type", values_to = "log_sd") %>%
mutate(reported = ifelse(type == "log_control_sd", control_sd_report, treatment_sd_report))
# Create the plot
imputed_sd_plot <- ggplot(data_long, aes(x = factor(study_id), y = log_sd, color = control_sd_report)) +
geom_point(size = 2, alpha = 0.5) + scale_color_manual(values = RColorBrewer::brewer.pal(n = 8,
name = "Dark2")[c(1, 2)]) + theme_bw() + theme(legend.position = "none", axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"), plot.caption = element_text(size = 10,
color = "gray10", face = "italic"), axis.text.x = element_text(angle = 90,
hjust = 1, vjust = 0.5)) + labs(caption = "Points with 'red' indicate missing standard deviations that were imputed",
x = "Study ID", y = "Log10(SD Value)")
# Print the plot
print(imputed_sd_plot)
Calculate effect sizes and sampling variances
# Make sure all data is numeric
data <- data %>%
mutate(treatment_mean = as.numeric(treatment_mean), treatment_sd = as.numeric(treatment_sd),
treatment_n = as.numeric(treatment_n), control_mean = as.numeric(control_mean),
control_sd = as.numeric(control_sd), control_n = as.numeric(control_n))
# Calculate log response ratio (lnRR)
lnRR <- escalc(measure = "ROM", m1i = treatment_mean, sd1i = treatment_sd, n1i = treatment_n,
m2i = control_mean, sd2i = control_sd, n2i = control_n, data = data)
# Calculate log coefficient variation ratio (lnCVR)
lnCVR <- escalc(measure = "CVR", m1i = treatment_mean, sd1i = treatment_sd, n1i = treatment_n,
m2i = control_mean, sd2i = control_sd, n2i = control_n, data = data)
# Calculate the standardised mean difference for sensitivity analysis
SMD <- escalc(measure = "SMD", m1i = treatment_mean, sd1i = treatment_sd, n1i = treatment_n,
m2i = control_mean, sd2i = control_sd, n2i = control_n, data = data)
# Calculate log variation ratio (lnVR)
lnVR <- escalc(measure = "VR", m1i = treatment_mean, sd1i = treatment_sd, n1i = treatment_n,
m2i = control_mean, sd2i = control_sd, n2i = control_n, data = data)
# Summary statistics of effect size estimates
effect_size_summaries <- list(lnRR = summary(lnRR$yi), lnCVR = summary(lnCVR$yi),
SMD = summary(SMD$yi), VR = summary(lnVR$yi))
# Summary statistics of sampling variances
sampling_variance_summaries <- list(lnRR = summary(lnRR$vi), lnCVR = summary(lnCVR$vi),
SMD = summary(SMD$vi), VR = summary(lnVR$vi))
# Calculate precision for each effect size estimate with checks
lnRR$precision <- ifelse(lnRR$vi > 0, 1/sqrt(lnRR$vi), NA)
lnCVR$precision <- ifelse(lnCVR$vi > 0, 1/sqrt(lnCVR$vi), NA)
SMD$precision <- ifelse(SMD$vi > 0, 1/sqrt(SMD$vi), NA)
lnVR$precision <- ifelse(lnVR$vi > 0, 1/sqrt(lnVR$vi), NA)
# Merge each of the effect size with precision
effect_size_metrics_set <- data.frame(lnRR = lnRR$yi, lnRRv = lnRR$vi, lnRR_precision = lnRR$precision,
lnVR = lnVR$yi, lnVRv = lnVR$vi, lnVR_precision = lnVR$precision, lnCVR = lnCVR$yi,
lnCVRv = lnCVR$vi, lnCVR_precision = lnCVR$precision, SMD = SMD$yi, SMDv = SMD$vi,
SMD_precision = SMD$precision, control_imputed = data$control_sd_report, treatment_imputed = data$treatment_sd_report)
# Bind the effect size metrics set to the main data
data <- cbind(data, effect_size_metrics_set)
# Check if `effect_direction` is 'change' and not NA, then multiply `lnRR` by
# -1; otherwise, keep original `lnRR`
data$lnRR <- ifelse(!is.na(data$effect_direction) & data$effect_direction == "change",
-1 * data$lnRR, data$lnRR)
# Select specific columns including the new precision columns
effect_size_metrics_set_kable <- data[, which(colnames(data) %in% c("study_id", "exp_id",
"assay_id", "species_english", "pesticide", "behaviour_assay", "effect_direction",
"lnRR", "lnRRv", "lnRR_precision", "lnCVR", "lnCVRv", "lnCVR_precision", "lnVR",
"lnVRv", "lnVR_precision", "SMD", "SMDv", "SMD_precision", "control_imputed",
"treatment_imputed"))] %>%
dfround(digits = 3)
# Table of the effect sizes
kable(effect_size_metrics_set_kable, "html") %>%
kable_styling("bordered", position = "left") %>%
scroll_box(width = "250%", height = "800px")| study_id | exp_id | assay_id | species_english | pesticide | behaviour_assay | effect_direction | lnRR | lnRRv | lnRR_precision | lnVR | lnVRv | lnVR_precision | lnCVR | lnCVRv | lnCVR_precision | SMD | SMDv | SMD_precision | control_imputed | treatment_imputed |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| bellot_2024 | bellot_2024_exp_001 | bellot_2024_exp_001_assay_001 | zebrafish | glyphosate | time spent in conspecific zone | NA | -0.290 | 0.011 | 9.632 | -0.567 | 0.069 | 3.806 | -0.278 | 0.080 | 3.539 | -0.937 | 0.143 | 2.641 | No | No |
| bellot_2024 | bellot_2024_exp_002 | bellot_2024_exp_002_assay_001 | zebrafish | glyphosate | time spent in conspecific zone | NA | -0.298 | 0.014 | 8.482 | -0.275 | 0.069 | 3.806 | 0.023 | 0.083 | 3.472 | -0.876 | 0.142 | 2.658 | No | No |
| boscolo_2018 | boscolo_2018_exp_001 | boscolo_2018_exp_001_assay_001 | Nile tilapia | diuron | total frequency of aggressive interactions | NA | 0.056 | 0.113 | 2.975 | -0.005 | 0.091 | 3.317 | -0.061 | 0.204 | 2.215 | 0.066 | 0.167 | 2.449 | No | No |
| boscolo_2018 | boscolo_2018_exp_002 | boscolo_2018_exp_002_assay_001 | Nile tilapia | DCPMU | total frequency of aggressive interactions | NA | -0.701 | 0.096 | 3.224 | -0.952 | 0.091 | 3.317 | -0.251 | 0.187 | 2.312 | -0.757 | 0.179 | 2.366 | No | No |
| boscolo_2018 | boscolo_2018_exp_003 | boscolo_2018_exp_003_assay_001 | Nile tilapia | DCA | total frequency of aggressive interactions | NA | -1.127 | 0.096 | 3.224 | -1.378 | 0.091 | 3.317 | -0.251 | 0.187 | 2.312 | -1.055 | 0.190 | 2.295 | No | No |
| bridi_2017 | bridi_2017_exp_001 | bridi_2017_exp_001_assay_001 | zebrafish | glyphosate | time spent close to stimulus | NA | -0.293 | 0.006 | 12.766 | 0.016 | 0.040 | 5.000 | 0.310 | 0.046 | 4.656 | -1.051 | 0.088 | 3.380 | No | No |
| bridi_2017 | bridi_2017_exp_002 | bridi_2017_exp_002_assay_001 | zebrafish | glyphosate | time spent close to stimulus | NA | -0.269 | 0.008 | 11.494 | 0.194 | 0.040 | 5.000 | 0.463 | 0.048 | 4.585 | -0.884 | 0.084 | 3.441 | No | No |
| bridi_2017 | bridi_2017_exp_003 | bridi_2017_exp_003_assay_001 | zebrafish | glyphosate | time spent close to stimulus | NA | -0.267 | 0.009 | 10.446 | 0.324 | 0.040 | 5.000 | 0.592 | 0.049 | 4.510 | -0.810 | 0.083 | 3.466 | No | No |
| bridi_2017 | bridi_2017_exp_004 | bridi_2017_exp_004_assay_001 | zebrafish | roundup | time spent close to stimulus | NA | -0.353 | 0.004 | 16.167 | -0.476 | 0.040 | 5.000 | -0.123 | 0.044 | 4.777 | -1.490 | 0.098 | 3.190 | No | No |
| bridi_2017 | bridi_2017_exp_005 | bridi_2017_exp_005_assay_001 | zebrafish | roundup | time spent close to stimulus | NA | -0.347 | 0.009 | 10.312 | 0.261 | 0.040 | 5.000 | 0.609 | 0.049 | 4.499 | -1.056 | 0.088 | 3.378 | No | No |
| bridi_2017 | bridi_2017_exp_006 | bridi_2017_exp_006_assay_001 | zebrafish | roundup | time spent close to stimulus | NA | -0.256 | 0.003 | 17.437 | -0.572 | 0.040 | 5.000 | -0.316 | 0.043 | 4.806 | -1.158 | 0.090 | 3.337 | No | No |
| bridi_2017 | bridi_2017_exp_001 | bridi_2017_exp_001_assay_002 | zebrafish | glyphosate | number of enteries | NA | -0.353 | 0.014 | 8.332 | -0.567 | 0.040 | 5.000 | -0.214 | 0.054 | 4.287 | -0.756 | 0.082 | 3.483 | No | No |
| bridi_2017 | bridi_2017_exp_002 | bridi_2017_exp_002_assay_002 | zebrafish | glyphosate | number of enteries | NA | -0.464 | 0.019 | 7.284 | -0.390 | 0.040 | 5.000 | 0.074 | 0.059 | 4.122 | -0.899 | 0.085 | 3.436 | No | No |
| bridi_2017 | bridi_2017_exp_003 | bridi_2017_exp_003_assay_002 | zebrafish | glyphosate | number of enteries | NA | -0.585 | 0.012 | 9.227 | -1.115 | 0.040 | 5.000 | -0.530 | 0.052 | 4.396 | -1.231 | 0.091 | 3.306 | No | No |
| bridi_2017 | bridi_2017_exp_004 | bridi_2017_exp_004_assay_002 | zebrafish | roundup | number of enteries | NA | -0.464 | 0.014 | 8.355 | -0.685 | 0.040 | 5.000 | -0.221 | 0.054 | 4.290 | -0.969 | 0.086 | 3.411 | No | No |
| bridi_2017 | bridi_2017_exp_005 | bridi_2017_exp_005_assay_002 | zebrafish | roundup | number of enteries | NA | -0.522 | 0.012 | 9.183 | -1.033 | 0.040 | 5.000 | -0.512 | 0.052 | 4.391 | -1.120 | 0.089 | 3.352 | No | No |
| bridi_2017 | bridi_2017_exp_006 | bridi_2017_exp_006_assay_002 | zebrafish | roundup | number of enteries | NA | -0.469 | 0.011 | 9.573 | -1.160 | 0.040 | 5.000 | -0.691 | 0.051 | 4.432 | -1.044 | 0.087 | 3.382 | No | No |
| chen_2022 | chen_2022_exp_001 | chen_2022_exp_001_assay_001 | zebrafish | difenoconazole | contact time | NA | -0.356 | 0.005 | 13.918 | -0.166 | 0.143 | 2.646 | 0.190 | 0.148 | 2.599 | -2.362 | 0.424 | 1.535 | No | No |
| chen_2022 | chen_2022_exp_002 | chen_2022_exp_002_assay_001 | zebrafish | difenoconazole | contact time | NA | 0.046 | 0.015 | 8.073 | 0.968 | 0.143 | 2.646 | 0.922 | 0.158 | 2.514 | 0.174 | 0.251 | 1.996 | No | No |
| chen_2022 | chen_2022_exp_003 | chen_2022_exp_003_assay_001 | zebrafish | difenoconazole | contact time | NA | -0.972 | 0.022 | 6.739 | 0.154 | 0.143 | 2.646 | 1.126 | 0.165 | 2.463 | -4.176 | 0.795 | 1.122 | No | No |
| chen_2022 | chen_2022_exp_001 | chen_2022_exp_001_assay_002 | zebrafish | difenoconazole | contact time | NA | -0.019 | 0.008 | 10.923 | 0.335 | 0.143 | 2.646 | 0.354 | 0.151 | 2.571 | -0.097 | 0.250 | 1.999 | No | No |
| chen_2022 | chen_2022_exp_002 | chen_2022_exp_002_assay_002 | zebrafish | difenoconazole | contact time | NA | -0.026 | 0.005 | 14.810 | -0.243 | 0.143 | 2.646 | -0.218 | 0.147 | 2.605 | -0.179 | 0.251 | 1.996 | No | No |
| chen_2022 | chen_2022_exp_003 | chen_2022_exp_003_assay_002 | zebrafish | difenoconazole | contact time | NA | 0.110 | 0.006 | 13.188 | 0.148 | 0.143 | 2.646 | 0.037 | 0.149 | 2.594 | 0.685 | 0.265 | 1.944 | No | No |
| chen_2022 | chen_2022_exp_001 | chen_2022_exp_001_assay_003 | zebrafish | difenoconazole | contact time | NA | -0.178 | 0.006 | 13.198 | 1.578 | 0.143 | 2.646 | 1.756 | 0.149 | 2.594 | -1.205 | 0.295 | 1.840 | No | No |
| chen_2022 | chen_2022_exp_002 | chen_2022_exp_002_assay_003 | zebrafish | difenoconazole | contact time | NA | -0.059 | 0.001 | 30.618 | 0.785 | 0.143 | 2.646 | 0.844 | 0.144 | 2.636 | -0.875 | 0.274 | 1.911 | No | No |
| chen_2022 | chen_2022_exp_003 | chen_2022_exp_003_assay_003 | zebrafish | difenoconazole | contact time | NA | -0.301 | 0.000 | 49.758 | -0.123 | 0.143 | 2.646 | 0.178 | 0.143 | 2.642 | -7.125 | 1.836 | 0.738 | No | No |
| chung_2023 | chung_2023_exp_001 | chung_2023_exp_001_assay_001 | zebrafish | imidacloprid | distance between male and female | change | -0.838 | 0.039 | 5.076 | 0.932 | 0.111 | 3.000 | 0.094 | 0.150 | 2.583 | 1.553 | 0.260 | 1.960 | No | No |
| chung_2023 | chung_2023_exp_002 | chung_2023_exp_002_assay_001 | zebrafish | imidacloprid | distance between male and female | change | -0.948 | 0.036 | 5.240 | 0.982 | 0.111 | 3.000 | 0.034 | 0.148 | 2.603 | 1.791 | 0.280 | 1.889 | No | No |
| chung_2023 | chung_2023_exp_003 | chung_2023_exp_003_assay_001 | zebrafish | imidacloprid | distance between male and female | change | -1.193 | 0.029 | 5.881 | 0.972 | 0.111 | 3.000 | -0.221 | 0.140 | 2.672 | 2.624 | 0.372 | 1.639 | No | No |
| chung_2023 | chung_2023_exp_001 | chung_2023_exp_001_assay_002 | zebrafish | imidacloprid | male confrontation distance | change | 0.209 | 0.022 | 6.698 | -0.011 | 0.111 | 3.000 | 0.198 | 0.133 | 2.738 | -0.607 | 0.209 | 2.186 | No | No |
| chung_2023 | chung_2023_exp_002 | chung_2023_exp_002_assay_002 | zebrafish | imidacloprid | male confrontation distance | change | 0.298 | 0.023 | 6.603 | -0.077 | 0.111 | 3.000 | 0.222 | 0.134 | 2.731 | -0.856 | 0.218 | 2.140 | No | No |
| chung_2023 | chung_2023_exp_003 | chung_2023_exp_003_assay_002 | zebrafish | imidacloprid | male confrontation distance | change | 0.293 | 0.024 | 6.432 | -0.029 | 0.111 | 3.000 | 0.264 | 0.135 | 2.719 | -0.825 | 0.217 | 2.147 | No | No |
| faria_2021 | faria_2021_exp_001 | faria_2021_exp_001_assay_001 | zebrafish | glyphosate | average interfish distance | change | 0.322 | 0.012 | 9.045 | -0.116 | 0.053 | 4.353 | 0.206 | 0.065 | 3.922 | -0.914 | 0.111 | 3.006 | No | No |
| faria_2021 | faria_2021_exp_002 | faria_2021_exp_002_assay_001 | zebrafish | glyphosate | average interfish distance | change | 0.416 | 0.009 | 10.454 | -0.542 | 0.056 | 4.243 | -0.126 | 0.065 | 3.931 | -1.304 | 0.128 | 2.799 | No | No |
| faria_2021 | faria_2021_exp_001 | faria_2021_exp_001_assay_002 | zebrafish | glyphosate | farthest distance | change | 0.171 | 0.012 | 9.302 | -0.217 | 0.053 | 4.359 | -0.045 | 0.064 | 3.947 | -0.489 | 0.103 | 3.116 | No | No |
| faria_2021 | faria_2021_exp_002 | faria_2021_exp_002_assay_002 | zebrafish | glyphosate | farthest distance | change | 0.334 | 0.010 | 9.915 | -0.548 | 0.054 | 4.300 | -0.214 | 0.064 | 3.945 | -0.975 | 0.115 | 2.951 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_001 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.078 | 0.010 | 10.036 | -0.071 | 0.059 | 4.123 | 0.007 | 0.069 | 3.814 | -0.255 | 0.112 | 2.988 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_001 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.170 | 0.008 | 10.898 | -0.343 | 0.059 | 4.123 | -0.173 | 0.067 | 3.856 | -0.592 | 0.116 | 2.936 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_001 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.369 | 0.008 | 11.510 | -0.686 | 0.059 | 4.123 | -0.317 | 0.066 | 3.882 | -1.278 | 0.134 | 2.734 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_002 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.041 | 0.003 | 17.903 | 0.184 | 0.059 | 4.123 | 0.225 | 0.062 | 4.018 | -0.242 | 0.112 | 2.989 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_002 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.168 | 0.004 | 15.245 | 0.299 | 0.059 | 4.123 | 0.467 | 0.063 | 3.980 | -0.859 | 0.121 | 2.870 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_002 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.301 | 0.002 | 22.047 | -0.483 | 0.059 | 4.123 | -0.182 | 0.061 | 4.053 | -2.069 | 0.171 | 2.422 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_003 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.020 | 0.003 | 18.875 | 0.373 | 0.059 | 4.123 | 0.392 | 0.062 | 4.028 | -0.122 | 0.111 | 2.997 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_003 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.145 | 0.002 | 20.546 | 0.119 | 0.059 | 4.123 | 0.264 | 0.061 | 4.043 | -0.982 | 0.125 | 2.834 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_003 | zebrafish | azoxystrobin | distance in region of attraction | NA | -0.195 | 0.002 | 20.942 | 0.038 | 0.059 | 4.123 | 0.233 | 0.061 | 4.045 | -1.348 | 0.136 | 2.708 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_004 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.155 | 0.008 | 10.982 | 0.131 | 0.059 | 4.123 | 0.286 | 0.067 | 3.860 | -0.565 | 0.116 | 2.942 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_004 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.251 | 0.004 | 15.548 | -0.731 | 0.059 | 4.123 | -0.480 | 0.063 | 3.985 | -1.193 | 0.131 | 2.764 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_004 | zebrafish | azoxystrobin | frequency in region of attraction | NA | -0.505 | 0.004 | 15.270 | -0.923 | 0.059 | 4.123 | -0.418 | 0.063 | 3.981 | -2.196 | 0.178 | 2.370 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_005 | zebrafish | azoxystrobin | time near female | NA | -0.134 | 0.005 | 14.261 | -1.166 | 0.059 | 4.123 | -1.032 | 0.064 | 3.961 | -0.592 | 0.116 | 2.936 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_005 | zebrafish | azoxystrobin | time near female | NA | -0.202 | 0.005 | 14.907 | -1.931 | 0.059 | 4.123 | -1.729 | 0.063 | 3.974 | -0.895 | 0.122 | 2.860 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_005 | zebrafish | azoxystrobin | time near female | NA | -0.369 | 0.006 | 13.171 | -0.937 | 0.059 | 4.123 | -0.568 | 0.065 | 3.935 | -1.417 | 0.139 | 2.682 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_006 | zebrafish | azoxystrobin | time near male | NA | -0.068 | 0.001 | 27.074 | -1.718 | 0.059 | 4.123 | -1.649 | 0.060 | 4.076 | -0.583 | 0.116 | 2.938 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_006 | zebrafish | azoxystrobin | time near male | NA | -0.228 | 0.002 | 24.211 | -0.836 | 0.059 | 4.123 | -0.608 | 0.061 | 4.065 | -1.680 | 0.150 | 2.579 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_006 | zebrafish | azoxystrobin | time near male | NA | -0.266 | 0.002 | 21.141 | -0.444 | 0.059 | 4.123 | -0.178 | 0.061 | 4.047 | -1.764 | 0.154 | 2.546 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_007 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.038 | 0.000 | 70.325 | 0.676 | 0.059 | 4.123 | 0.638 | 0.059 | 4.116 | 0.866 | 0.122 | 2.869 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_007 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.054 | 0.000 | 51.146 | 1.072 | 0.059 | 4.123 | 1.018 | 0.059 | 4.110 | 0.888 | 0.122 | 2.862 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_007 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.110 | 0.000 | 63.192 | 0.881 | 0.059 | 4.123 | 0.771 | 0.059 | 4.114 | 2.181 | 0.177 | 2.376 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_008 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.121 | 0.007 | 12.370 | 1.071 | 0.059 | 4.123 | 0.950 | 0.065 | 3.912 | 0.466 | 0.114 | 2.960 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_008 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.301 | 0.009 | 10.666 | 1.418 | 0.059 | 4.123 | 1.117 | 0.068 | 3.846 | 0.923 | 0.123 | 2.852 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_008 | zebrafish | azoxystrobin | distance in region of contact | NA | 0.400 | 0.008 | 11.311 | 1.451 | 0.059 | 4.123 | 1.051 | 0.067 | 3.874 | 1.253 | 0.133 | 2.743 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_009 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.021 | 0.003 | 17.229 | 0.007 | 0.059 | 4.123 | -0.014 | 0.062 | 4.010 | 0.120 | 0.111 | 2.997 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_009 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.112 | 0.002 | 21.033 | -0.452 | 0.059 | 4.123 | -0.565 | 0.061 | 4.046 | 0.792 | 0.120 | 2.889 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_009 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.236 | 0.002 | 21.244 | -0.371 | 0.059 | 4.123 | -0.607 | 0.061 | 4.048 | 1.728 | 0.153 | 2.560 | No | No |
| guo_2023 | guo_2023_exp_001 | guo_2023_exp_001_assay_010 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.007 | 0.001 | 31.868 | -0.518 | 0.059 | 4.123 | -0.525 | 0.060 | 4.089 | 0.071 | 0.111 | 2.999 | No | No |
| guo_2023 | guo_2023_exp_002 | guo_2023_exp_002_assay_010 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.123 | 0.004 | 15.072 | 0.932 | 0.059 | 4.123 | 0.808 | 0.063 | 3.977 | 0.581 | 0.116 | 2.939 | No | No |
| guo_2023 | guo_2023_exp_003 | guo_2023_exp_003_assay_010 | zebrafish | azoxystrobin | frequency in region of contact | NA | 0.233 | 0.002 | 24.017 | 0.393 | 0.059 | 4.123 | 0.160 | 0.061 | 4.064 | 1.769 | 0.155 | 2.543 | No | No |
| gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp_001_assay_001 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | -0.135 | 0.056 | 4.230 | 0.085 | 0.077 | 3.606 | 0.220 | 0.133 | 2.744 | -0.211 | 0.144 | 2.638 | No | No |
| gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp_002_assay_001 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | 0.036 | 0.039 | 5.085 | -0.098 | 0.077 | 3.606 | -0.134 | 0.116 | 2.941 | 0.067 | 0.143 | 2.645 | No | No |
| gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp_003_assay_001 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | -0.217 | 0.064 | 3.958 | 0.107 | 0.077 | 3.606 | 0.325 | 0.141 | 2.665 | -0.323 | 0.145 | 2.629 | No | No |
| gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp_001_assay_002 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | 0.133 | 0.062 | 4.001 | 0.221 | 0.077 | 3.606 | 0.089 | 0.139 | 2.678 | 0.193 | 0.144 | 2.640 | No | No |
| gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp_002_assay_002 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | 0.303 | 0.045 | 4.702 | 0.039 | 0.077 | 3.606 | -0.265 | 0.122 | 2.861 | 0.534 | 0.148 | 2.600 | No | No |
| gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp_003_assay_002 | zebrafish | pyriproxyfen | total aggressive behaviours towards mirror | NA | 0.050 | 0.070 | 3.769 | 0.244 | 0.077 | 3.606 | 0.194 | 0.147 | 2.605 | 0.069 | 0.143 | 2.645 | No | No |
| gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp_001_assay_003 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | -0.019 | 0.017 | 7.656 | 0.334 | 0.083 | 3.464 | 0.352 | 0.100 | 3.156 | -0.054 | 0.154 | 2.549 | No | No |
| gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp_002_assay_003 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | -0.089 | 0.016 | 7.961 | 0.204 | 0.083 | 3.464 | 0.293 | 0.099 | 3.176 | -0.272 | 0.155 | 2.538 | No | No |
| gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp_003_assay_003 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | 0.055 | 0.009 | 10.742 | -0.257 | 0.083 | 3.464 | -0.312 | 0.092 | 3.297 | 0.227 | 0.155 | 2.541 | No | No |
| gusso_2020 | gusso_2020_exp_001 | gusso_2020_exp_001_assay_004 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | -0.019 | 0.017 | 7.656 | 0.334 | 0.083 | 3.464 | 0.352 | 0.100 | 3.156 | -0.054 | 0.154 | 2.549 | No | No |
| gusso_2020 | gusso_2020_exp_002 | gusso_2020_exp_002_assay_004 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | -0.089 | 0.016 | 7.961 | 0.204 | 0.083 | 3.464 | 0.293 | 0.099 | 3.176 | -0.272 | 0.155 | 2.538 | No | No |
| gusso_2020 | gusso_2020_exp_003 | gusso_2020_exp_003_assay_004 | zebrafish | pyriproxyfen | time spent in the area closest to the stimulus aquarium | NA | 0.055 | 0.009 | 10.742 | -0.257 | 0.083 | 3.464 | -0.312 | 0.092 | 3.297 | 0.227 | 0.155 | 2.541 | No | No |
| hawkey_2020 | hawkey_2020_exp_001 | hawkey_2020_exp_001_assay_001 | zebrafish | DDT | total distance moved | NA | -0.298 | 0.008 | 11.177 | 0.250 | 0.029 | 5.873 | 0.548 | 0.037 | 5.199 | -0.834 | 0.061 | 4.041 | No | No |
| hawkey_2020 | hawkey_2020_exp_002 | hawkey_2020_exp_002_assay_001 | zebrafish | DDT | total distance moved | NA | -0.145 | 0.005 | 14.077 | 0.066 | 0.029 | 5.873 | 0.211 | 0.034 | 5.420 | -0.486 | 0.058 | 4.152 | No | No |
| hawkey_2020 | hawkey_2020_exp_003 | hawkey_2020_exp_003_assay_001 | zebrafish | chlorpyrifos | change in position | NA | 0.733 | 0.412 | 1.558 | -0.171 | 0.053 | 4.335 | -0.904 | 0.465 | 1.466 | 0.414 | 0.103 | 3.114 | No | No |
| hawkey_2020 | hawkey_2020_exp_004 | hawkey_2020_exp_004_assay_001 | zebrafish | chlorpyrifos | change in position | NA | 1.127 | 0.378 | 1.626 | -0.024 | 0.048 | 4.583 | -1.150 | 0.426 | 1.533 | 0.754 | 0.097 | 3.205 | No | No |
| hawkey_2020 | hawkey_2020_exp_005 | hawkey_2020_exp_005_assay_001 | zebrafish | chlorpyrifos | change in position | NA | 1.458 | 0.381 | 1.621 | 0.298 | 0.050 | 4.467 | -1.161 | 0.431 | 1.524 | 1.001 | 0.107 | 3.051 | No | No |
| hawkey_2021 | hawkey_2021_exp_001 | hawkey_2021_exp_001_assay_001 | zebrafish | chlorpyrifos | distance | NA | -0.095 | 0.007 | 12.325 | -0.208 | 0.022 | 6.745 | -0.113 | 0.029 | 5.917 | -0.240 | 0.043 | 4.804 | No | No |
| hawkey_2021 | hawkey_2021_exp_002 | hawkey_2021_exp_002_assay_001 | zebrafish | DDT | distance | NA | 0.038 | 0.009 | 10.761 | 0.138 | 0.023 | 6.550 | 0.101 | 0.032 | 5.595 | 0.086 | 0.046 | 4.683 | No | No |
| hawkey_2021 | hawkey_2021_exp_003 | hawkey_2021_exp_003_assay_001 | zebrafish | chlorpyrifos ; DDT | distance | NA | 0.206 | 0.007 | 12.349 | -0.098 | 0.027 | 6.059 | -0.304 | 0.034 | 5.439 | 0.572 | 0.055 | 4.261 | No | No |
| hawkey_2021 | hawkey_2021_exp_001 | hawkey_2021_exp_001_assay_002 | zebrafish | chlorpyrifos | change in position | NA | 0.435 | 0.082 | 3.498 | 0.195 | 0.022 | 6.745 | -0.240 | 0.104 | 3.105 | 0.317 | 0.044 | 4.792 | No | No |
| hawkey_2021 | hawkey_2021_exp_002 | hawkey_2021_exp_002_assay_002 | zebrafish | DDT | change in position | NA | 0.486 | 0.085 | 3.439 | 0.234 | 0.023 | 6.550 | -0.252 | 0.108 | 3.045 | 0.358 | 0.046 | 4.649 | No | No |
| hawkey_2021 | hawkey_2021_exp_003 | hawkey_2021_exp_003_assay_002 | zebrafish | chlorpyrifos ; DDT | change in position | NA | -0.576 | 0.524 | 1.381 | 0.363 | 0.027 | 6.059 | 0.938 | 0.552 | 1.347 | -0.237 | 0.053 | 4.329 | No | No |
| hawkey_2021 | hawkey_2021_exp_004 | hawkey_2021_exp_004_assay_001 | zebrafish | chlorpyrifos | change in position | NA | 0.361 | 0.100 | 3.158 | -0.063 | 0.029 | 5.914 | -0.424 | 0.129 | 2.786 | 0.277 | 0.056 | 4.221 | No | No |
| hawkey_2021 | hawkey_2021_exp_005 | hawkey_2021_exp_005_assay_001 | zebrafish | DDT | change in position | NA | -1.696 | 3.273 | 0.553 | 0.249 | 0.027 | 6.081 | 1.944 | 3.300 | 0.550 | -0.438 | 0.054 | 4.306 | No | No |
| hawkey_2021 | hawkey_2021_exp_006 | hawkey_2021_exp_006_assay_001 | zebrafish | chlorpyrifos ; DDT | change in position | NA | -0.850 | 0.412 | 1.558 | -0.278 | 0.037 | 5.226 | 0.572 | 0.448 | 1.493 | -0.387 | 0.072 | 3.733 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_001 | killifish | roundup | number of persecutions | NA | -0.345 | 0.066 | 3.885 | -0.325 | 0.125 | 2.828 | 0.020 | 0.191 | 2.287 | -0.589 | 0.232 | 2.077 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_002 | killifish | roundup | number of persecutions | NA | -0.276 | 0.064 | 3.961 | -0.294 | 0.125 | 2.828 | -0.019 | 0.189 | 2.302 | -0.482 | 0.229 | 2.091 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_003 | killifish | roundup | number of copulation attempts | NA | -0.629 | 0.140 | 2.671 | -1.030 | 0.125 | 2.828 | -0.401 | 0.265 | 1.942 | -0.634 | 0.233 | 2.070 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_004 | killifish | roundup | number of copulation attempts | NA | -0.457 | 0.126 | 2.813 | -1.050 | 0.125 | 2.828 | -0.593 | 0.251 | 1.995 | -0.499 | 0.229 | 2.089 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_005 | killifish | roundup | number of copulations | NA | -0.860 | 0.068 | 3.843 | -0.522 | 0.125 | 2.828 | 0.338 | 0.193 | 2.278 | -1.475 | 0.283 | 1.881 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_006 | killifish | roundup | number of copulations | NA | -0.935 | 0.066 | 3.894 | -0.616 | 0.125 | 2.828 | 0.318 | 0.191 | 2.288 | -1.588 | 0.292 | 1.850 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_007 | killifish | roundup | mating success | NA | -0.268 | 0.036 | 5.294 | 0.847 | 0.125 | 2.828 | 1.116 | 0.161 | 2.495 | -0.707 | 0.236 | 2.058 | No | No |
| hued_2011 | hued_2011_exp_001 | hued_2011_exp_001_assay_008 | killifish | roundup | mating success | NA | -0.435 | 0.048 | 4.543 | 0.847 | 0.125 | 2.828 | 1.283 | 0.173 | 2.401 | -1.061 | 0.253 | 1.986 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_001 | zebrafish | paclobutrazol | mirror biting time | NA | -0.686 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_001 | zebrafish | paclobutrazol | mirror biting time | NA | -0.805 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_002 | zebrafish | paclobutrazol | duration of stay on mirror side | NA | -1.644 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_002 | zebrafish | paclobutrazol | duration of stay on mirror side | NA | -1.669 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_003 | zebrafish | paclobutrazol | interaction time percentage | NA | -0.154 | 0.075 | 3.654 | 0.383 | 0.034 | 5.385 | 0.536 | 0.109 | 3.023 | -0.148 | 0.067 | 3.868 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_003 | zebrafish | paclobutrazol | interaction time percentage | NA | -0.292 | 0.338 | 1.720 | 1.116 | 0.034 | 5.385 | 1.408 | 0.372 | 1.639 | -0.145 | 0.067 | 3.868 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_004 | zebrafish | paclobutrazol | longest duration of stay in seperator side | NA | -0.072 | 4.307 | 0.482 | 0.028 | 0.034 | 5.385 | 0.100 | 4.341 | 0.480 | -0.009 | 0.067 | 3.873 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_004 | zebrafish | paclobutrazol | longest duration of stay in seperator side | NA | -0.387 | 3.936 | 0.504 | -0.372 | 0.034 | 5.385 | 0.015 | 3.971 | 0.502 | -0.048 | 0.067 | 3.872 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_006 | zebrafish | paclobutrazol | average distance to seperator | change | -0.384 | 0.686 | 1.208 | 0.069 | 0.034 | 5.385 | -0.315 | 0.720 | 1.178 | 0.122 | 0.067 | 3.869 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_006 | zebrafish | paclobutrazol | average distance to seperator | change | -0.487 | 0.524 | 1.381 | -0.393 | 0.034 | 5.385 | -0.880 | 0.559 | 1.338 | 0.198 | 0.067 | 3.864 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_007 | zebrafish | paclobutrazol | average speed | NA | -0.429 | 0.141 | 2.664 | -0.086 | 0.034 | 5.385 | 0.343 | 0.175 | 2.388 | -0.301 | 0.067 | 3.851 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_007 | zebrafish | paclobutrazol | average speed | NA | -0.403 | 0.072 | 3.719 | -0.719 | 0.034 | 5.385 | -0.316 | 0.107 | 3.060 | -0.350 | 0.068 | 3.844 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_008 | zebrafish | paclobutrazol | time in top | NA | -1.558 | 5.893 | 0.412 | 0.403 | 0.034 | 5.385 | 1.961 | 5.928 | 0.411 | -0.331 | 0.068 | 3.847 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_008 | zebrafish | paclobutrazol | time in top | NA | -0.245 | 0.516 | 1.392 | 0.383 | 0.034 | 5.385 | 0.628 | 0.551 | 1.348 | -0.092 | 0.067 | 3.871 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_009 | zebrafish | paclobutrazol | distance between individuals | change | -0.020 | 0.047 | 4.611 | -0.228 | 0.034 | 5.385 | -0.248 | 0.082 | 3.502 | 0.024 | 0.067 | 3.873 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_009 | zebrafish | paclobutrazol | distance between individuals | change | 0.035 | 0.070 | 3.770 | 0.136 | 0.034 | 5.385 | 0.170 | 0.105 | 3.089 | -0.034 | 0.067 | 3.873 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_010 | zebrafish | paclobutrazol | average shoal area | change | -0.089 | 0.043 | 4.838 | -1.375 | 0.034 | 5.385 | -1.464 | 0.077 | 3.599 | 0.114 | 0.067 | 3.870 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_010 | zebrafish | paclobutrazol | average shoal area | change | -0.127 | 0.045 | 4.716 | -0.982 | 0.034 | 5.385 | -1.109 | 0.079 | 3.548 | 0.160 | 0.067 | 3.867 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_011 | zebrafish | paclobutrazol | average nearest neighbor distance | change | -0.065 | 0.086 | 3.415 | -0.382 | 0.034 | 5.385 | -0.448 | 0.120 | 2.884 | 0.058 | 0.067 | 3.872 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_011 | zebrafish | paclobutrazol | average nearest neighbor distance | change | 0.001 | 0.122 | 2.863 | 0.001 | 0.034 | 5.385 | 0.002 | 0.156 | 2.528 | 0.000 | 0.067 | 3.873 | No | No |
| hussian_2020 | hussian_2020_exp_001 | hussian_2020_exp_001_assay_012 | zebrafish | paclobutrazol | average farthest neighbor distance | change | 0.266 | 0.074 | 3.685 | -0.687 | 0.034 | 5.385 | -0.421 | 0.108 | 3.041 | -0.234 | 0.067 | 3.860 | No | No |
| hussian_2020 | hussian_2020_exp_002 | hussian_2020_exp_002_assay_012 | zebrafish | paclobutrazol | average farthest neighbor distance | change | 0.085 | 0.109 | 3.033 | -0.032 | 0.034 | 5.385 | 0.053 | 0.143 | 2.643 | -0.065 | 0.067 | 3.872 | No | No |
| ibrahim_2023 | ibrahim_2023_exp_001 | ibrahim_2023_exp_001_assay_001 | Nile tilapia | mancozeb | number of chases | NA | NA | NA | NA | 2.565 | 0.111 | 3.000 | NA | NA | NA | 4.599 | 0.729 | 1.171 | No | No |
| ibrahim_2023 | ibrahim_2023_exp_002 | ibrahim_2023_exp_001_assay_002 | Nile tilapia | mancozeb | number of chases | NA | NA | NA | NA | 2.197 | 0.111 | 3.000 | NA | NA | NA | 8.513 | 2.012 | 0.705 | No | No |
| ibrahim_2023 | ibrahim_2023_exp_003 | ibrahim_2023_exp_001_assay_003 | Nile tilapia | mancozeb | number of chases | NA | NA | NA | NA | 1.946 | 0.111 | 3.000 | NA | NA | NA | 12.719 | 4.244 | 0.485 | No | No |
| ibrahim_2023 | ibrahim_2023_exp_004 | ibrahim_2023_exp_001_assay_004 | Nile tilapia | mancozeb | number of chases | NA | NA | NA | NA | 2.398 | 0.111 | 3.000 | NA | NA | NA | 8.375 | 1.954 | 0.715 | No | No |
| ibrahim_2023 | ibrahim_2023_exp_005 | ibrahim_2023_exp_001_assay_005 | Nile tilapia | mancozeb | number of chases | NA | NA | NA | NA | 2.708 | 0.111 | 3.000 | NA | NA | NA | 6.581 | 1.283 | 0.883 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_001 | zebrafish | rotenone | time spent in the left arm | NA | -0.313 | 0.071 | 3.765 | -0.534 | 0.071 | 3.742 | -0.221 | 0.142 | 2.654 | -0.397 | 0.136 | 2.712 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_002 | zebrafish | rotenone | time spent in the left arm | NA | 0.128 | 0.094 | 3.260 | -0.436 | 0.071 | 3.742 | -0.564 | 0.166 | 2.458 | 0.152 | 0.134 | 2.735 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_003 | zebrafish | rotenone | time spent in the left arm | NA | 0.035 | 0.078 | 3.583 | -0.050 | 0.071 | 3.742 | -0.085 | 0.149 | 2.588 | 0.044 | 0.133 | 2.738 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_004 | zebrafish | rotenone | time spent in the left arm | NA | 0.533 | 0.027 | 6.069 | -0.532 | 0.071 | 3.742 | -1.065 | 0.099 | 3.185 | 1.385 | 0.165 | 2.460 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_005 | zebrafish | rotenone | time spent in the left arm | NA | -0.129 | 0.018 | 7.548 | -0.498 | 0.071 | 3.742 | -0.369 | 0.089 | 3.352 | -0.337 | 0.135 | 2.719 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_006 | zebrafish | rotenone | time spent in the left arm | NA | -0.737 | 0.191 | 2.288 | 0.590 | 0.071 | 3.742 | 1.327 | 0.262 | 1.952 | -0.801 | 0.144 | 2.635 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_007 | zebrafish | rotenone | time spent in the left arm | NA | 0.001 | 0.027 | 6.038 | 0.357 | 0.071 | 3.742 | 0.355 | 0.099 | 3.180 | 0.003 | 0.133 | 2.739 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_008 | zebrafish | rotenone | time spent in the left arm | NA | -0.424 | 0.044 | 4.759 | -0.095 | 0.071 | 3.742 | 0.329 | 0.116 | 2.941 | -0.741 | 0.142 | 2.649 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_009 | zebrafish | rotenone | time spent in the left arm | NA | 0.185 | 0.085 | 3.435 | 0.578 | 0.071 | 3.742 | 0.394 | 0.156 | 2.531 | 0.217 | 0.134 | 2.731 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_010 | zebrafish | rotenone | time spent in the left arm | NA | -0.301 | 0.118 | 2.906 | -0.076 | 0.071 | 3.742 | 0.226 | 0.190 | 2.295 | -0.316 | 0.135 | 2.722 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_011 | zebrafish | rotenone | time spent in the left arm | NA | -0.150 | 0.047 | 4.590 | 1.422 | 0.071 | 3.742 | 1.572 | 0.119 | 2.900 | -0.261 | 0.134 | 2.727 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_012 | zebrafish | rotenone | time spent in the left arm | NA | -0.005 | 0.035 | 5.351 | -0.808 | 0.071 | 3.742 | -0.803 | 0.106 | 3.066 | -0.010 | 0.133 | 2.739 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_013 | zebrafish | rotenone | time spent in the left arm | NA | -0.288 | 0.171 | 2.418 | 0.526 | 0.071 | 3.742 | 0.814 | 0.242 | 2.031 | -0.270 | 0.135 | 2.726 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_014 | zebrafish | rotenone | time spent in the left arm | NA | -0.325 | 0.078 | 3.573 | 0.736 | 0.071 | 3.742 | 1.061 | 0.150 | 2.584 | -0.465 | 0.137 | 2.702 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_015 | zebrafish | rotenone | time spent in the left arm | NA | 0.260 | 0.025 | 6.302 | 0.938 | 0.071 | 3.742 | 0.679 | 0.097 | 3.217 | 0.534 | 0.138 | 2.691 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_016 | zebrafish | rotenone | time spent in the left arm | NA | -0.292 | 0.179 | 2.362 | 0.581 | 0.071 | 3.742 | 0.872 | 0.251 | 1.997 | -0.269 | 0.135 | 2.726 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_017 | zebrafish | rotenone | time spent in the left arm | NA | -0.110 | 0.053 | 4.351 | 0.065 | 0.071 | 3.742 | 0.175 | 0.124 | 2.837 | -0.172 | 0.134 | 2.734 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_018 | zebrafish | rotenone | time spent in the left arm | NA | 0.221 | 0.056 | 4.219 | 0.123 | 0.071 | 3.742 | -0.098 | 0.128 | 2.799 | 0.332 | 0.135 | 2.720 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_019 | zebrafish | rotenone | time spent in the left arm | NA | 0.218 | 0.131 | 2.759 | -0.162 | 0.071 | 3.742 | -0.380 | 0.203 | 2.221 | 0.220 | 0.134 | 2.730 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_020 | zebrafish | rotenone | time spent in the left arm | NA | 0.529 | 0.061 | 4.044 | 0.265 | 0.071 | 3.742 | -0.264 | 0.133 | 2.746 | 0.769 | 0.143 | 2.643 | No | No |
| ilie_2021 | ilie_2021_exp_001 | ilie_2021_exp_001_assay_021 | zebrafish | rotenone | time spent in the left arm | NA | 0.362 | 0.032 | 5.565 | 0.439 | 0.071 | 3.742 | 0.077 | 0.104 | 3.105 | 0.688 | 0.141 | 2.661 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_001 | zebrafish | rotenone | percentage of time in left arm | NA | 0.810 | 0.036 | 5.305 | 1.083 | 0.250 | 2.000 | 0.274 | 0.286 | 1.871 | 2.000 | 0.600 | 1.291 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_002 | zebrafish | rotenone | percentage of time in left arm | NA | 0.935 | 0.485 | 1.436 | 1.285 | 0.250 | 2.000 | 0.350 | 0.735 | 1.166 | 0.587 | 0.417 | 1.548 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_003 | zebrafish | rotenone | percentage of time in left arm | NA | 0.916 | 0.089 | 3.353 | 0.795 | 0.250 | 2.000 | -0.121 | 0.339 | 1.718 | 1.578 | 0.524 | 1.381 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_004 | zebrafish | rotenone | percentage of time in left arm | NA | -0.937 | 0.538 | 1.363 | -0.290 | 0.250 | 2.000 | 0.647 | 0.788 | 1.126 | -0.817 | 0.433 | 1.519 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_005 | zebrafish | rotenone | percentage of time in left arm | NA | 0.208 | 0.517 | 1.391 | 0.156 | 0.250 | 2.000 | -0.052 | 0.767 | 1.142 | 0.165 | 0.401 | 1.578 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_006 | zebrafish | rotenone | percentage of time in left arm | NA | -0.264 | 0.376 | 1.630 | 0.802 | 0.250 | 2.000 | 1.065 | 0.626 | 1.264 | -0.271 | 0.404 | 1.574 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_007 | zebrafish | rotenone | percentage of time in left arm | NA | -0.565 | 0.208 | 2.192 | 0.045 | 0.250 | 2.000 | 0.610 | 0.458 | 1.477 | -0.781 | 0.431 | 1.524 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_008 | zebrafish | rotenone | percentage of time in left arm | NA | -1.592 | 0.312 | 1.790 | -1.332 | 0.250 | 2.000 | 0.260 | 0.562 | 1.334 | -1.289 | 0.483 | 1.439 | No | No |
| ilie_2022 | ilie_2022_exp_001 | ilie_2022_exp_001_assay_009 | zebrafish | rotenone | percentage of time in left arm | NA | -1.359 | 0.310 | 1.797 | -1.441 | 0.250 | 2.000 | -0.081 | 0.560 | 1.337 | -1.009 | 0.451 | 1.489 | No | No |
| jaensson_2007 | jaensson_2007_exp_001 | jaensson_2007_exp_001_assay_001 | brown trout | cypermethrin | number of courting events per six minutes | NA | 0.468 | 0.254 | 1.985 | 0.379 | 0.067 | 3.858 | -0.089 | 0.321 | 1.765 | 0.330 | 0.127 | 2.811 | No | No |
| jaensson_2007 | jaensson_2007_exp_002 | jaensson_2007_exp_002_assay_001 | brown trout | cypermethrin | time near female | NA | 0.622 | 0.177 | 2.379 | 0.232 | 0.119 | 2.898 | -0.391 | 0.296 | 1.839 | 0.659 | 0.219 | 2.135 | No | No |
| jaensson_2007 | jaensson_2007_exp_003 | jaensson_2007_exp_002_assay_002 | brown trout | cypermethrin | time near female | NA | -1.544 | 0.241 | 2.037 | -1.776 | 0.161 | 2.494 | -0.232 | 0.402 | 1.578 | -0.719 | 0.280 | 1.891 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_001 | Japanese medaka | chlorpyrifos | swimming speed | NA | -0.069 | 0.058 | 4.137 | -0.270 | 0.200 | 2.236 | -0.201 | 0.258 | 1.967 | -0.151 | 0.334 | 1.730 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_002 | Japanese medaka | chlorpyrifos | swimming speed | NA | 0.685 | 0.026 | 6.230 | 1.276 | 0.200 | 2.236 | 0.591 | 0.226 | 2.105 | 1.812 | 0.470 | 1.458 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_003 | Japanese medaka | chlorpyrifos | duration | NA | -0.226 | 0.075 | 3.662 | -0.604 | 0.200 | 2.236 | -0.377 | 0.275 | 1.908 | -0.420 | 0.341 | 1.713 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_004 | Japanese medaka | chlorpyrifos | duration | NA | -0.672 | 0.122 | 2.868 | -1.229 | 0.200 | 2.236 | -0.557 | 0.322 | 1.763 | -0.827 | 0.362 | 1.662 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_005 | Japanese medaka | chlorpyrifos | frequency | NA | 0.654 | 0.359 | 1.669 | -0.288 | 0.200 | 2.236 | -0.942 | 0.559 | 1.337 | 0.705 | 0.354 | 1.681 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_006 | Japanese medaka | chlorpyrifos | frequency | NA | 0.325 | 0.030 | 5.791 | 0.528 | 0.200 | 2.236 | 0.203 | 0.230 | 2.086 | 0.951 | 0.371 | 1.642 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_007 | Japanese medaka | chlorpyrifos | duration | NA | 0.527 | 0.161 | 2.489 | -1.528 | 0.200 | 2.236 | -2.056 | 0.361 | 1.663 | 0.907 | 0.368 | 1.649 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_008 | Japanese medaka | chlorpyrifos | duration | NA | 0.097 | 0.011 | 9.391 | -0.995 | 0.200 | 2.236 | -1.093 | 0.211 | 2.175 | 0.506 | 0.344 | 1.705 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_009 | Japanese medaka | chlorpyrifos | frequency | NA | 0.222 | 0.128 | 2.799 | -0.772 | 0.200 | 2.236 | -0.994 | 0.328 | 1.747 | 0.358 | 0.339 | 1.718 | No | No |
| khalil_2013 | khalil_2013_exp_001 | khalil_2013_exp_001_assay_010 | Japanese medaka | chlorpyrifos | frequency | NA | 0.026 | 0.022 | 6.773 | -0.987 | 0.200 | 2.236 | -1.014 | 0.222 | 2.123 | 0.096 | 0.334 | 1.731 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_001 | Japanese medaka | chlorpyrifos | frequency | NA | -0.152 | 0.036 | 5.281 | -0.095 | 0.333 | 1.732 | 0.057 | 0.369 | 1.646 | -0.492 | 0.515 | 1.393 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_002 | Japanese medaka | chlorpyrifos | frequency | NA | 0.314 | 0.020 | 7.034 | 1.070 | 0.333 | 1.732 | 0.757 | 0.354 | 1.682 | 1.216 | 0.592 | 1.299 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_003 | Japanese medaka | chlorpyrifos | frequency | NA | -1.068 | 0.017 | 7.719 | -2.148 | 0.333 | 1.732 | -1.080 | 0.350 | 1.690 | -3.264 | 1.166 | 0.926 | No | No |
| khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp_002_assay_001 | Japanese medaka | chlorpyrifos | frequency | NA | -1.191 | 0.036 | 5.263 | -1.127 | 0.333 | 1.732 | 0.063 | 0.369 | 1.645 | -3.127 | 1.111 | 0.949 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_004 | Japanese medaka | chlorpyrifos | duration | NA | 0.000 | 0.062 | 4.022 | 0.000 | 0.333 | 1.732 | 0.000 | 0.395 | 1.591 | 0.000 | 0.500 | 1.414 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_005 | Japanese medaka | chlorpyrifos | duration | NA | 0.000 | 0.028 | 5.999 | 0.000 | 0.333 | 1.732 | 0.000 | 0.361 | 1.664 | 0.000 | 0.500 | 1.414 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_006 | Japanese medaka | chlorpyrifos | duration | NA | 0.000 | 0.026 | 6.175 | 0.000 | 0.333 | 1.732 | 0.000 | 0.360 | 1.668 | 0.000 | 0.500 | 1.414 | No | No |
| khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp_002_assay_002 | Japanese medaka | chlorpyrifos | duration | NA | 0.000 | 0.062 | 4.022 | 0.000 | 0.333 | 1.732 | 0.000 | 0.395 | 1.591 | 0.000 | 0.500 | 1.414 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_007 | Japanese medaka | chlorpyrifos | frequency | NA | -0.147 | 0.020 | 7.007 | 0.230 | 0.333 | 1.732 | 0.377 | 0.354 | 1.681 | -0.648 | 0.526 | 1.379 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_008 | Japanese medaka | chlorpyrifos | frequency | NA | 0.032 | 0.025 | 6.332 | 0.981 | 0.333 | 1.732 | 0.949 | 0.358 | 1.671 | 0.122 | 0.501 | 1.413 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_009 | Japanese medaka | chlorpyrifos | frequency | NA | -0.067 | 0.023 | 6.541 | -0.117 | 0.333 | 1.732 | -0.050 | 0.357 | 1.674 | -0.269 | 0.505 | 1.408 | No | No |
| khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp_002_assay_003 | Japanese medaka | chlorpyrifos | frequency | NA | -0.917 | 0.036 | 5.252 | -0.158 | 0.333 | 1.732 | 0.759 | 0.370 | 1.645 | -3.473 | 1.254 | 0.893 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_010 | Japanese medaka | chlorpyrifos | duration | NA | -0.147 | 0.020 | 7.007 | 0.230 | 0.333 | 1.732 | 0.377 | 0.354 | 1.681 | -0.648 | 0.526 | 1.379 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_011 | Japanese medaka | chlorpyrifos | duration | NA | 0.032 | 0.025 | 6.332 | 0.981 | 0.333 | 1.732 | 0.949 | 0.358 | 1.671 | 0.122 | 0.501 | 1.413 | No | No |
| khalil_2017 | khalil_2017_exp_001 | khalil_2017_exp_001_assay_012 | Japanese medaka | chlorpyrifos | duration | NA | -0.067 | 0.023 | 6.541 | -0.117 | 0.333 | 1.732 | -0.050 | 0.357 | 1.674 | -0.269 | 0.505 | 1.408 | No | No |
| khalil_2017 | khalil_2017_exp_002 | khalil_2017_exp_002_assay_004 | Japanese medaka | chlorpyrifos | duration | NA | -0.917 | 0.036 | 5.252 | -0.158 | 0.333 | 1.732 | 0.759 | 0.370 | 1.645 | -3.473 | 1.254 | 0.893 | No | No |
| lei_2022 | lei_2022_exp_001 | lei_2022_exp_001_assay_001 | zebrafish | deltamethrin | proportion of time in near zone | NA | 0.055 | 0.001 | 38.992 | -0.256 | 0.067 | 3.873 | -0.310 | 0.067 | 3.854 | 0.743 | 0.134 | 2.736 | No | No |
| lei_2022 | lei_2022_exp_002 | lei_2022_exp_002_assay_001 | zebrafish | deltamethrin | proportion of time in near zone | NA | 0.057 | 0.001 | 40.021 | -0.331 | 0.067 | 3.873 | -0.389 | 0.067 | 3.855 | 0.800 | 0.135 | 2.722 | No | No |
| lei_2022 | lei_2022_exp_003 | lei_2022_exp_003_assay_001 | zebrafish | deltamethrin | proportion of time in near zone | NA | 0.045 | 0.001 | 37.855 | -0.185 | 0.067 | 3.873 | -0.230 | 0.067 | 3.853 | 0.585 | 0.130 | 2.770 | No | No |
| lei_2022 | lei_2022_exp_001 | lei_2022_exp_001_assay_002 | zebrafish | deltamethrin | nearest neighbour distance | change | -0.109 | 0.002 | 22.202 | 0.210 | 0.043 | 4.796 | 0.102 | 0.046 | 4.688 | 0.679 | 0.088 | 3.368 | No | No |
| lei_2022 | lei_2022_exp_002 | lei_2022_exp_002_assay_002 | zebrafish | deltamethrin | nearest neighbour distance | change | 0.061 | 0.001 | 28.213 | -0.547 | 0.043 | 4.796 | -0.486 | 0.045 | 4.728 | -0.483 | 0.086 | 3.415 | No | No |
| lei_2022 | lei_2022_exp_003 | lei_2022_exp_003_assay_002 | zebrafish | deltamethrin | nearest neighbour distance | change | -0.042 | 0.001 | 27.245 | -0.327 | 0.043 | 4.796 | -0.369 | 0.045 | 4.723 | 0.328 | 0.084 | 3.441 | No | No |
| lei_2022 | lei_2022_exp_001 | lei_2022_exp_001_assay_003 | zebrafish | deltamethrin | inter individual difference | change | -0.355 | 0.003 | 16.971 | 0.355 | 0.043 | 4.796 | 0.000 | 0.047 | 4.615 | 1.670 | 0.112 | 2.983 | No | No |
| lei_2022 | lei_2022_exp_002 | lei_2022_exp_002_assay_003 | zebrafish | deltamethrin | inter individual difference | change | -0.302 | 0.003 | 16.971 | 0.302 | 0.043 | 4.796 | 0.000 | 0.047 | 4.615 | 1.426 | 0.105 | 3.093 | No | No |
| lei_2022 | lei_2022_exp_003 | lei_2022_exp_003_assay_003 | zebrafish | deltamethrin | inter individual difference | change | -0.057 | 0.003 | 16.971 | 0.057 | 0.043 | 4.796 | 0.000 | 0.047 | 4.615 | 0.272 | 0.084 | 3.448 | No | No |
| leite_2023 | leite_2023_exp_001 | leite_2023_exp_001_assay_001 | Iberian barbel | esfenvalerate | cohesion | change | 0.143 | 0.062 | 4.002 | 0.029 | 0.091 | 3.317 | 0.171 | 0.153 | 2.554 | -0.227 | 0.168 | 2.442 | No | No |
| leite_2023 | leite_2023_exp_002 | leite_2023_exp_002_assay_001 | Iberian barbel | esfenvalerate | cohesion | change | 0.134 | 0.061 | 4.044 | 0.019 | 0.091 | 3.317 | 0.153 | 0.152 | 2.564 | -0.215 | 0.168 | 2.442 | No | No |
| leite_2023 | leite_2023_exp_003 | leite_2023_exp_003_assay_001 | Bleak | esfenvalerate | cohesion | change | -1.125 | 0.078 | 3.575 | 0.091 | 0.091 | 3.317 | -1.034 | 0.169 | 2.432 | 2.097 | 0.258 | 1.968 | No | No |
| leite_2023 | leite_2023_exp_004 | leite_2023_exp_004_assay_001 | Bleak | esfenvalerate | cohesion | change | -1.058 | 0.086 | 3.404 | 0.350 | 0.091 | 3.317 | -0.708 | 0.177 | 2.375 | 1.619 | 0.221 | 2.126 | No | No |
| lin_2024 | lin_2024_exp_001 | lin_2024_exp_001_assay_001 | zebrafish | DDT | inter-individual distance | change | 0.167 | 0.001 | 36.457 | 0.032 | 1.000 | 1.000 | 0.199 | 1.001 | 1.000 | -3.474 | 2.509 | 0.631 | No | No |
| lin_2024 | lin_2024_exp_002 | lin_2024_exp_002_assay_001 | zebrafish | DDT | inter-individual distance | change | 0.020 | 0.001 | 39.448 | 0.160 | 1.000 | 1.000 | 0.180 | 1.001 | 1.000 | -0.442 | 1.024 | 0.988 | No | No |
| lin_2024 | lin_2024_exp_001 | lin_2024_exp_001_assay_002 | zebrafish | DDT | time in contact percentage | NA | -0.019 | 0.000 | 84.865 | -0.129 | 0.143 | 2.646 | -0.110 | 0.143 | 2.644 | -0.762 | 0.268 | 1.931 | No | No |
| lin_2024 | lin_2024_exp_002 | lin_2024_exp_002_assay_002 | zebrafish | DDT | time in contact percentage | NA | -0.091 | 0.000 | 82.316 | 0.452 | 0.143 | 2.646 | 0.543 | 0.143 | 2.644 | -3.609 | 0.657 | 1.234 | No | No |
| lin_2024 | lin_2024_exp_001 | lin_2024_exp_001_assay_003 | zebrafish | DDT | mirror attack per minute | NA | 0.399 | 0.002 | 21.302 | 0.395 | 0.091 | 3.317 | -0.005 | 0.093 | 3.277 | 3.249 | 0.387 | 1.608 | No | No |
| lin_2024 | lin_2024_exp_002 | lin_2024_exp_002_assay_003 | zebrafish | DDT | mirror attack per minute | NA | -0.254 | 0.003 | 18.610 | -0.271 | 0.091 | 3.317 | -0.017 | 0.094 | 3.265 | -1.836 | 0.237 | 2.055 | No | No |
| liu_2023 | liu_2023_exp_001 | liu_2023_exp_001_assay_001 | zebrafish | fenpropathrin | time in conspecific segment | NA | 0.283 | 0.219 | 2.137 | 0.327 | 0.111 | 3.000 | 0.045 | 0.330 | 1.741 | 0.253 | 0.202 | 2.227 | No | No |
| liu_2023 | liu_2023_exp_001 | liu_2023_exp_001_assay_002 | zebrafish | fenpropathrin | duration of fight control vs fenpropathrin | NA | -0.600 | 0.094 | 3.269 | -0.109 | 0.097 | 3.207 | 0.491 | 0.191 | 2.289 | -0.867 | 0.193 | 2.275 | No | No |
| liu_2023 | liu_2023_exp_001 | liu_2023_exp_001_assay_003 | zebrafish | fenpropathrin | biting numbers | NA | -0.234 | 0.026 | 6.253 | -0.086 | 0.127 | 2.806 | 0.148 | 0.153 | 2.560 | -0.664 | 0.237 | 2.053 | No | No |
| liu_2023a | liu_2023a_exp_001 | liu_2023a_exp_001_assay_001 | zebrafish | imidacloprid | time spent in conspecific zone | NA | 0.021 | 0.002 | 21.258 | 0.087 | 0.077 | 3.606 | 0.066 | 0.079 | 3.555 | 0.166 | 0.143 | 2.641 | No | No |
| liu_2023a | liu_2023a_exp_002 | liu_2023a_exp_002_assay_001 | zebrafish | imidacloprid | time spent in conspecific zone | NA | 0.048 | 0.003 | 19.374 | 0.276 | 0.077 | 3.606 | 0.228 | 0.080 | 3.545 | 0.342 | 0.145 | 2.627 | No | No |
| liu_2023a | liu_2023a_exp_003 | liu_2023a_exp_003_assay_001 | zebrafish | imidacloprid | time spent in conspecific zone | NA | 0.117 | 0.001 | 27.527 | -0.526 | 0.077 | 3.606 | -0.643 | 0.078 | 3.575 | 1.214 | 0.169 | 2.431 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_001 | sailfin mollie | atrazine | time in preference zone of female | NA | 0.022 | 0.011 | 9.709 | 0.176 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | 0.066 | 0.100 | 3.161 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_001 | sailfin mollie | atrazine | time in preference zone of female | NA | -0.051 | 0.011 | 9.709 | 0.103 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -0.154 | 0.100 | 3.158 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_002 | sailfin mollie | atrazine | time in preference zone of male | NA | -0.553 | 0.011 | 9.709 | -0.400 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.632 | 0.133 | 2.739 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_002 | sailfin mollie | atrazine | time in preference zone of male | NA | -0.299 | 0.011 | 9.709 | -0.145 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -0.903 | 0.110 | 3.012 | No | No |
| maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp_003_assay_001 | sailfin mollie | atrazine | time in preference zone of female | NA | -0.383 | 0.011 | 9.709 | -0.229 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.150 | 0.117 | 2.929 | No | No |
| maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp_004_assay_001 | sailfin mollie | atrazine | time in preference zone of female | NA | -0.363 | 0.011 | 9.709 | -0.209 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.092 | 0.115 | 2.950 | No | No |
| maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp_003_assay_002 | sailfin mollie | atrazine | time in preference zone of male | NA | -0.373 | 0.011 | 9.709 | -0.220 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.123 | 0.116 | 2.939 | No | No |
| maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp_004_assay_002 | sailfin mollie | atrazine | time in preference zone of male | NA | -0.303 | 0.011 | 9.709 | -0.149 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -0.915 | 0.110 | 3.009 | No | No |
| maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp_003_assay_003 | sailfin mollie | atrazine | mean total time with dummy | NA | -0.269 | 0.011 | 9.709 | -0.115 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -0.813 | 0.108 | 3.039 | No | No |
| maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp_004_assay_003 | sailfin mollie | atrazine | mean total time with dummy | NA | -0.187 | 0.011 | 9.709 | -0.033 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -0.567 | 0.104 | 3.101 | No | No |
| maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp_003_assay_004 | sailfin mollie | atrazine | mean total time with dummy | NA | -0.376 | 0.011 | 9.709 | -0.223 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.132 | 0.116 | 2.936 | No | No |
| maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp_004_assay_004 | sailfin mollie | atrazine | mean total time with dummy | NA | -0.336 | 0.011 | 9.709 | -0.183 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -1.015 | 0.113 | 2.977 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_003 | sailfin mollie | atrazine | time with smaller male (small and intermediate male present) | NA | 0.257 | 0.046 | 4.683 | 0.838 | 0.053 | 4.359 | 0.581 | 0.098 | 3.191 | 0.346 | 0.101 | 3.139 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_003 | sailfin mollie | atrazine | time with smaller male (small and intermediate male present) | NA | 0.292 | 0.038 | 5.161 | 0.742 | 0.053 | 4.359 | 0.449 | 0.090 | 3.330 | 0.434 | 0.102 | 3.126 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_004 | sailfin mollie | atrazine | time with larger male (small and intermediate male present) | NA | -0.176 | 0.035 | 5.358 | 0.686 | 0.053 | 4.359 | 0.861 | 0.087 | 3.381 | -0.309 | 0.101 | 3.144 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_004 | sailfin mollie | atrazine | time with larger male (small and intermediate male present) | NA | 0.011 | 0.023 | 6.594 | 0.617 | 0.053 | 4.359 | 0.606 | 0.076 | 3.636 | 0.022 | 0.100 | 3.162 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_005 | sailfin mollie | atrazine | time with smaller male (small and large male present) | NA | 0.059 | 0.070 | 3.793 | 1.297 | 0.053 | 4.359 | 1.238 | 0.122 | 2.861 | 0.068 | 0.100 | 3.161 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_005 | sailfin mollie | atrazine | time with smaller male (small and large male present) | NA | 0.000 | 0.024 | 6.449 | 0.621 | 0.053 | 4.359 | 0.620 | 0.077 | 3.611 | 0.000 | 0.100 | 3.162 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_006 | sailfin mollie | atrazine | time with larger male (small and large male present) | NA | -0.225 | 0.038 | 5.117 | 1.087 | 0.053 | 4.359 | 1.313 | 0.091 | 3.318 | -0.394 | 0.102 | 3.132 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_006 | sailfin mollie | atrazine | time with larger male (small and large male present) | NA | -0.225 | 0.038 | 5.117 | 1.087 | 0.053 | 4.359 | 1.313 | 0.091 | 3.318 | -0.394 | 0.102 | 3.132 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_007 | sailfin mollie | atrazine | time with smaller male (intermediate and large male present) | NA | 0.002 | 0.046 | 4.680 | 0.850 | 0.053 | 4.359 | 0.848 | 0.098 | 3.190 | 0.003 | 0.100 | 3.162 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_007 | sailfin mollie | atrazine | time with smaller male (intermediate and large male present) | NA | 0.219 | 0.032 | 5.559 | 0.855 | 0.053 | 4.359 | 0.637 | 0.085 | 3.430 | 0.353 | 0.102 | 3.138 | No | No |
| maclaren_2023 | maclaren_2023_exp_001 | maclaren_2023_exp_001_assay_008 | sailfin mollie | atrazine | time with larger male (intermediate and large male present) | NA | -0.519 | 0.042 | 4.863 | 0.650 | 0.053 | 4.359 | 1.170 | 0.095 | 3.246 | -0.953 | 0.111 | 2.997 | No | No |
| maclaren_2023 | maclaren_2023_exp_002 | maclaren_2023_exp_002_assay_008 | sailfin mollie | atrazine | time with larger male (intermeditate and large male present) | NA | -0.303 | 0.029 | 5.873 | 0.656 | 0.053 | 4.359 | 0.958 | 0.082 | 3.500 | -0.612 | 0.105 | 3.091 | No | No |
| maclaren_2023 | maclaren_2023_exp_003 | maclaren_2023_exp_003_assay_005 | sailfin mollie | atrazine | mean time in mirror zone | NA | -1.155 | 0.011 | 9.709 | -1.001 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -2.972 | 0.210 | 2.180 | No | No |
| maclaren_2023 | maclaren_2023_exp_004 | maclaren_2023_exp_004_assay_005 | sailfin mollie | atrazine | mean time in mirror zone | NA | -0.711 | 0.011 | 9.709 | -0.557 | 0.053 | 4.359 | 0.154 | 0.063 | 3.977 | -2.040 | 0.152 | 2.565 | No | No |
| oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp_001_assay_001 | zebrafish | carbendazim | mean number of recordings | NA | -0.263 | 0.046 | 4.679 | -0.467 | 0.049 | 4.526 | -0.204 | 0.094 | 3.253 | -0.351 | 0.095 | 3.253 | No | No |
| oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp_001_assay_002 | zebrafish | carbendazim | mean number of recordings | NA | -0.156 | 0.031 | 5.713 | -0.040 | 0.048 | 4.577 | 0.116 | 0.078 | 3.572 | -0.266 | 0.092 | 3.299 | No | No |
| oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp_001_assay_003 | zebrafish | carbendazim | mean number of recordings | NA | -0.464 | 0.019 | 7.263 | -0.851 | 0.048 | 4.583 | -0.387 | 0.067 | 3.876 | -0.888 | 0.100 | 3.164 | No | No |
| oliveira_2024 | oliveira_2024_exp_001 | oliveira_2024_exp_001_assay_004 | zebrafish | carbendazim | mean number of recordings | NA | -0.711 | 0.012 | 9.310 | -0.791 | 0.046 | 4.686 | -0.080 | 0.057 | 4.185 | -1.734 | 0.120 | 2.889 | No | No |
| olsen_2020 | olsen_2020_exp_001 | olsen_2020_exp_001_assay_001 | brown trout | iodocarb | time with females | NA | 0.406 | 0.211 | 2.175 | 2.348 | 0.208 | 2.191 | 1.942 | 0.420 | 1.544 | 0.330 | 0.347 | 1.697 | No | No |
| paredes_2019 | paredes_2019_exp_001 | paredes_2019_exp_001_assay_001 | zebrafish | triadimefon | number of bites towards its reflex | NA | 0.376 | 0.079 | 3.558 | -0.141 | 0.167 | 2.449 | -0.517 | 0.246 | 2.018 | 0.713 | 0.304 | 1.814 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_001 | killifish | roundup | duration | NA | -0.056 | 0.002 | 21.199 | 0.341 | 0.053 | 4.359 | 0.397 | 0.055 | 4.270 | -0.370 | 0.102 | 3.135 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_001 | killifish | roundup transorb | duration | NA | -0.067 | 0.002 | 22.754 | 0.223 | 0.053 | 4.359 | 0.290 | 0.055 | 4.281 | -0.478 | 0.103 | 3.118 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_001 | killifish | roundup WG | duration | NA | -0.173 | 0.003 | 19.502 | 0.341 | 0.053 | 4.359 | 0.514 | 0.055 | 4.254 | -1.083 | 0.115 | 2.953 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_002 | killifish | roundup | time close to mirror | NA | 0.060 | 0.003 | 18.652 | -0.182 | 0.053 | 4.359 | -0.242 | 0.056 | 4.245 | 0.348 | 0.102 | 3.139 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_002 | killifish | roundup transorb | time close to mirror | NA | -0.002 | 0.003 | 17.857 | -0.137 | 0.053 | 4.359 | -0.135 | 0.056 | 4.235 | -0.012 | 0.100 | 3.162 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_002 | killifish | roundup WG | time close to mirror | NA | 0.031 | 0.003 | 18.109 | -0.137 | 0.053 | 4.359 | -0.168 | 0.056 | 4.238 | 0.174 | 0.100 | 3.156 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_003 | killifish | roundup | time taken by pursuits | NA | 0.238 | 0.197 | 2.254 | 0.106 | 0.053 | 4.359 | -0.132 | 0.249 | 2.002 | 0.167 | 0.100 | 3.157 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_003 | killifish | roundup transorb | time taken by pursuits | NA | -0.789 | 0.174 | 2.399 | -1.079 | 0.053 | 4.359 | -0.289 | 0.226 | 2.102 | -0.480 | 0.103 | 3.118 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_003 | killifish | roundup WG | time taken by pursuits | NA | -0.311 | 0.182 | 2.343 | -0.537 | 0.053 | 4.359 | -0.226 | 0.235 | 2.064 | -0.214 | 0.101 | 3.153 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_004 | killifish | roundup | number of pursuits | NA | -0.076 | 0.065 | 3.914 | 0.348 | 0.053 | 4.359 | 0.424 | 0.118 | 2.912 | -0.093 | 0.100 | 3.161 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_004 | killifish | roundup transorb | number of pursuits | NA | -0.716 | 0.101 | 3.151 | -0.005 | 0.053 | 4.359 | 0.711 | 0.153 | 2.554 | -0.803 | 0.108 | 3.042 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_004 | killifish | roundup WG | number of pursuits | NA | -0.174 | 0.062 | 4.026 | 0.210 | 0.053 | 4.359 | 0.384 | 0.114 | 2.957 | -0.222 | 0.101 | 3.153 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_005 | killifish | roundup | attempts at copulation | NA | -0.186 | 0.100 | 3.163 | -0.352 | 0.053 | 4.359 | -0.166 | 0.153 | 2.560 | -0.179 | 0.100 | 3.156 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_005 | killifish | roundup transorb | attempts at copulation | NA | -0.973 | 0.202 | 2.227 | -0.521 | 0.053 | 4.359 | 0.451 | 0.254 | 1.983 | -0.687 | 0.106 | 3.073 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_005 | killifish | roundup WG | attempts at copulation | NA | -0.619 | 0.115 | 2.947 | -0.630 | 0.053 | 4.359 | -0.010 | 0.168 | 2.441 | -0.524 | 0.103 | 3.109 | No | No |
| sanchez_2021 | sanchez_2021_exp_001 | sanchez_2021_exp_001_assay_006 | killifish | roundup | number of actual copulations | NA | -0.006 | 0.146 | 2.621 | -0.464 | 0.053 | 4.359 | -0.458 | 0.198 | 2.246 | -0.005 | 0.100 | 3.162 | No | No |
| sanchez_2021 | sanchez_2021_exp_002 | sanchez_2021_exp_002_assay_006 | killifish | roundup transorb | number of actual copulations | NA | -1.130 | 0.197 | 2.255 | -1.187 | 0.053 | 4.359 | -0.057 | 0.249 | 2.003 | -0.623 | 0.105 | 3.088 | No | No |
| sanchez_2021 | sanchez_2021_exp_003 | sanchez_2021_exp_003_assay_006 | killifish | roundup WG | number of actual copulations | NA | -0.604 | 0.143 | 2.649 | -1.100 | 0.053 | 4.359 | -0.496 | 0.195 | 2.264 | -0.414 | 0.102 | 3.129 | No | No |
| schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp_001_assay_001 | zebrafish | atrazine | distance | NA | -0.047 | 0.003 | 17.402 | -1.099 | 0.143 | 2.646 | -1.051 | 0.146 | 2.616 | -0.382 | 0.255 | 1.982 | No | No |
| schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp_002_assay_001 | zebrafish | atrazine | distance | NA | 0.229 | 0.012 | 9.077 | 0.799 | 0.143 | 2.646 | 0.570 | 0.155 | 2.540 | 0.919 | 0.276 | 1.902 | No | No |
| schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp_001_assay_002 | zebrafish | atrazine | nearest neighbour distance | change | 0.105 | 0.002 | 20.364 | -0.492 | 0.143 | 2.646 | -0.388 | 0.145 | 2.624 | -0.986 | 0.280 | 1.889 | No | No |
| schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp_002_assay_002 | zebrafish | atrazine | nearest neighbour distance | change | -0.181 | 0.012 | 9.279 | 1.080 | 0.143 | 2.646 | 0.899 | 0.154 | 2.544 | 0.743 | 0.267 | 1.934 | No | No |
| schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp_001_assay_003 | zebrafish | atrazine | farthest neighbour distance | change | 0.014 | 0.004 | 16.133 | -0.368 | 0.143 | 2.646 | -0.354 | 0.147 | 2.611 | -0.105 | 0.250 | 1.999 | No | No |
| schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp_002_assay_003 | zebrafish | atrazine | farthest neighbour distance | change | -0.252 | 0.012 | 9.245 | 0.885 | 0.143 | 2.646 | 0.633 | 0.155 | 2.544 | 1.019 | 0.282 | 1.882 | No | No |
| schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp_001_assay_004 | zebrafish | atrazine | shoal area | change | 0.152 | 0.010 | 9.874 | -0.544 | 0.143 | 2.646 | -0.392 | 0.153 | 2.556 | -0.686 | 0.265 | 1.944 | No | No |
| schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp_002_assay_004 | zebrafish | atrazine | shoal area | change | -0.679 | 0.063 | 3.989 | 1.714 | 0.143 | 2.646 | 1.035 | 0.206 | 2.205 | 0.970 | 0.279 | 1.892 | No | No |
| schmidel_2014 | schmidel_2014_exp_001 | schmidel_2014_exp_001_assay_005 | zebrafish | atrazine | total number of interactions | NA | 0.059 | 0.005 | 13.975 | -0.533 | 0.143 | 2.646 | -0.592 | 0.148 | 2.600 | 0.399 | 0.255 | 1.980 | No | No |
| schmidel_2014 | schmidel_2014_exp_002 | schmidel_2014_exp_002_assay_005 | zebrafish | atrazine | total number of interactions | NA | -0.294 | 0.018 | 7.452 | 0.346 | 0.143 | 2.646 | 0.640 | 0.161 | 2.493 | -1.110 | 0.288 | 1.862 | No | No |
| shenoy_2012 | shenoy_2012_exp_001 | shenoy_2012_exp_001_assay_001 | guppy | atrazine | number of displays in absence of competing male | NA | -0.344 | 0.052 | 4.403 | 0.349 | 0.062 | 4.000 | 0.693 | 0.114 | 2.961 | -0.553 | 0.122 | 2.861 | No | No |
| shenoy_2012 | shenoy_2012_exp_002 | shenoy_2012_exp_002_assay_001 | guppy | atrazine | number of displays in absence of competing male | NA | -0.409 | 0.054 | 4.292 | 0.316 | 0.062 | 4.000 | 0.724 | 0.117 | 2.926 | -0.652 | 0.124 | 2.841 | No | No |
| shenoy_2012 | shenoy_2012_exp_001 | shenoy_2012_exp_001_assay_002 | guppy | atrazine | number of mating attempts in absence of competing male | NA | 0.155 | 0.039 | 5.073 | 0.563 | 0.062 | 4.000 | 0.408 | 0.101 | 3.141 | 0.255 | 0.119 | 2.904 | No | No |
| shenoy_2012 | shenoy_2012_exp_002 | shenoy_2012_exp_002_assay_002 | guppy | atrazine | number of mating attempts in absence of competing male | NA | -0.181 | 0.054 | 4.307 | 0.450 | 0.062 | 4.000 | 0.630 | 0.116 | 2.931 | -0.273 | 0.119 | 2.902 | No | No |
| silva_2005 | silva_2005_exp_001 | silva_2005_exp_001_assay_001 | guppy | chlorpyrifos | number of gonopodial thrusts | NA | -0.397 | 0.001 | 40.799 | -0.226 | 0.014 | 8.426 | 0.171 | 0.015 | 8.252 | -2.691 | 0.053 | 4.347 | No | No |
| silva_2005 | silva_2005_exp_002 | silva_2005_exp_002_assay_001 | guppy | chlorpyrifos | number of gonopodial thrusts | NA | -1.023 | 0.001 | 28.946 | -0.358 | 0.014 | 8.426 | 0.665 | 0.015 | 8.090 | -5.511 | 0.133 | 2.740 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_001 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.743 | 0.088 | 3.368 | 0.293 | 0.026 | 6.245 | -0.450 | 0.114 | 2.964 | 0.583 | 0.052 | 4.380 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_002 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.048 | 0.070 | 3.790 | -0.297 | 0.026 | 6.245 | -0.344 | 0.095 | 3.240 | 0.040 | 0.050 | 4.472 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_003 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.904 | 0.085 | 3.427 | 0.672 | 0.026 | 6.245 | -0.233 | 0.111 | 3.004 | 0.648 | 0.053 | 4.359 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_004 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.132 | 0.039 | 5.066 | -0.011 | 0.026 | 6.245 | -0.143 | 0.065 | 3.934 | 0.149 | 0.050 | 4.466 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_005 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.321 | 0.106 | 3.073 | 0.318 | 0.026 | 6.245 | -0.003 | 0.132 | 2.758 | 0.214 | 0.050 | 4.459 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_006 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.024 | 0.126 | 2.815 | 0.012 | 0.026 | 6.245 | -1.013 | 0.152 | 2.566 | 0.832 | 0.054 | 4.290 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_007 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.689 | 0.065 | 3.918 | -0.016 | 0.026 | 6.245 | -0.706 | 0.091 | 3.319 | 0.685 | 0.053 | 4.347 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_008 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.789 | 0.100 | 3.156 | -0.013 | 0.026 | 6.245 | -0.802 | 0.126 | 2.817 | 0.655 | 0.053 | 4.357 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_009 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.020 | 0.082 | 3.500 | 0.552 | 0.026 | 6.245 | -0.468 | 0.107 | 3.053 | 0.809 | 0.054 | 4.300 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_010 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.476 | 0.053 | 4.356 | -0.142 | 0.026 | 6.245 | -0.618 | 0.078 | 3.573 | 0.505 | 0.052 | 4.403 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_011 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.581 | 0.065 | 3.927 | -0.113 | 0.026 | 6.245 | -0.694 | 0.090 | 3.325 | 0.571 | 0.052 | 4.384 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_012 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.162 | 0.054 | 4.316 | -0.198 | 0.026 | 6.245 | -1.359 | 0.079 | 3.551 | 1.675 | 0.068 | 3.848 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_013 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.163 | 0.046 | 4.645 | -0.359 | 0.026 | 6.245 | -0.523 | 0.072 | 3.727 | 0.174 | 0.050 | 4.464 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_014 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.846 | 0.085 | 3.439 | -0.280 | 0.026 | 6.245 | -1.125 | 0.110 | 3.012 | 0.849 | 0.055 | 4.283 | No | No |
| stungaru_2019 | stungaru_2019_exp_001 | stungaru_2019_exp_001_assay_015 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.163 | 0.031 | 5.685 | -0.028 | 0.026 | 6.245 | -0.191 | 0.057 | 4.204 | 0.207 | 0.050 | 4.460 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_001 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.756 | 0.094 | 3.253 | 0.417 | 0.026 | 6.245 | -0.339 | 0.120 | 2.885 | 0.550 | 0.052 | 4.390 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_002 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.621 | 0.054 | 4.295 | -0.266 | 0.026 | 6.245 | -0.886 | 0.080 | 3.539 | 0.702 | 0.053 | 4.340 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_003 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.355 | 0.065 | 3.918 | 0.653 | 0.026 | 6.245 | -0.703 | 0.091 | 3.319 | 1.287 | 0.060 | 4.071 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_004 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.311 | 0.040 | 5.005 | 0.195 | 0.026 | 6.245 | -0.116 | 0.066 | 3.906 | 0.344 | 0.051 | 4.440 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_005 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.210 | 0.063 | 3.970 | 0.392 | 0.026 | 6.245 | -0.818 | 0.089 | 3.350 | 1.266 | 0.060 | 4.082 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_006 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.286 | 0.129 | 2.781 | 0.368 | 0.026 | 6.245 | -0.918 | 0.155 | 2.541 | 0.988 | 0.056 | 4.222 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_007 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.911 | 0.069 | 3.808 | 0.337 | 0.026 | 6.245 | -0.574 | 0.095 | 3.251 | 0.837 | 0.054 | 4.288 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_008 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.055 | 0.096 | 3.233 | 0.088 | 0.026 | 6.245 | -0.967 | 0.121 | 2.871 | 0.968 | 0.056 | 4.231 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_009 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.354 | 0.077 | 3.610 | 0.766 | 0.026 | 6.245 | -0.588 | 0.102 | 3.126 | 1.107 | 0.058 | 4.164 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_010 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.735 | 0.053 | 4.339 | 0.134 | 0.026 | 6.245 | -0.601 | 0.079 | 3.564 | 0.783 | 0.054 | 4.310 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_011 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.922 | 0.069 | 3.807 | 0.367 | 0.026 | 6.245 | -0.555 | 0.095 | 3.251 | 0.838 | 0.054 | 4.288 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_012 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.158 | 0.059 | 4.115 | 0.280 | 0.026 | 6.245 | -0.878 | 0.085 | 3.436 | 1.300 | 0.061 | 4.064 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_013 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.511 | 0.041 | 4.936 | -0.302 | 0.026 | 6.245 | -0.814 | 0.067 | 3.873 | 0.642 | 0.053 | 4.361 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_014 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.130 | 0.085 | 3.421 | 0.057 | 0.026 | 6.245 | -1.073 | 0.111 | 3.000 | 1.152 | 0.058 | 4.142 | No | No |
| stungaru_2019 | stungaru_2019_exp_002 | stungaru_2019_exp_002_assay_015 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.367 | 0.027 | 6.098 | -0.019 | 0.026 | 6.245 | -0.386 | 0.053 | 4.363 | 0.516 | 0.052 | 4.399 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_001 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.419 | 0.075 | 3.644 | -0.383 | 0.026 | 6.245 | -0.801 | 0.101 | 3.148 | 0.380 | 0.051 | 4.432 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_002 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.338 | 0.051 | 4.447 | -0.858 | 0.026 | 6.245 | -1.196 | 0.076 | 3.622 | 0.381 | 0.051 | 4.432 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_003 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.998 | 0.110 | 3.011 | 1.049 | 0.026 | 6.245 | 0.051 | 0.136 | 2.712 | 0.548 | 0.052 | 4.390 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_004 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.053 | 0.052 | 4.371 | 0.203 | 0.026 | 6.245 | 0.151 | 0.078 | 3.581 | 0.051 | 0.050 | 4.471 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_005 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.057 | 0.077 | 3.615 | 0.648 | 0.026 | 6.245 | -0.409 | 0.102 | 3.129 | 0.837 | 0.054 | 4.288 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_006 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.613 | 0.133 | 2.744 | -0.214 | 0.026 | 6.245 | -0.827 | 0.158 | 2.512 | 0.437 | 0.051 | 4.420 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_007 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.759 | 0.065 | 3.923 | 0.046 | 0.026 | 6.245 | -0.713 | 0.091 | 3.322 | 0.759 | 0.054 | 4.319 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_008 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.933 | 0.097 | 3.217 | 0.003 | 0.026 | 6.245 | -0.930 | 0.122 | 2.860 | 0.834 | 0.054 | 4.290 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_009 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.018 | 0.073 | 3.703 | 0.312 | 0.026 | 6.245 | -0.706 | 0.099 | 3.185 | 0.954 | 0.056 | 4.237 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_010 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.358 | 0.063 | 3.991 | 0.048 | 0.026 | 6.245 | -0.310 | 0.088 | 3.363 | 0.326 | 0.051 | 4.443 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_011 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.661 | 0.058 | 4.160 | -0.425 | 0.026 | 6.245 | -1.086 | 0.083 | 3.462 | 0.762 | 0.054 | 4.318 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_012 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.527 | 0.067 | 3.878 | -0.041 | 0.026 | 6.245 | -0.568 | 0.092 | 3.294 | 0.494 | 0.052 | 4.405 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_013 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.185 | 0.044 | 4.755 | -0.435 | 0.026 | 6.245 | -0.620 | 0.070 | 3.783 | 0.204 | 0.050 | 4.461 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_014 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.824 | 0.090 | 3.331 | -0.040 | 0.026 | 6.245 | -0.864 | 0.116 | 2.939 | 0.738 | 0.053 | 4.327 | No | No |
| stungaru_2019 | stungaru_2019_exp_003 | stungaru_2019_exp_003_assay_015 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.049 | 0.035 | 5.380 | -0.016 | 0.026 | 6.245 | -0.065 | 0.060 | 4.076 | 0.058 | 0.050 | 4.471 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_001 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.597 | 0.104 | 3.098 | 0.391 | 0.026 | 6.245 | -0.206 | 0.130 | 2.775 | 0.404 | 0.051 | 4.427 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_002 | zebrafish | deltamethrin | percentage of time in left arm | NA | -0.049 | 0.076 | 3.629 | -0.273 | 0.026 | 6.245 | -0.224 | 0.102 | 3.138 | -0.039 | 0.050 | 4.472 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_003 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.032 | 0.068 | 3.847 | 0.416 | 0.026 | 6.245 | -0.616 | 0.093 | 3.275 | 0.963 | 0.056 | 4.233 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_004 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.008 | 0.060 | 4.091 | 0.268 | 0.026 | 6.245 | 0.260 | 0.085 | 3.422 | 0.007 | 0.050 | 4.472 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_005 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.964 | 0.075 | 3.663 | 0.511 | 0.026 | 6.245 | -0.454 | 0.100 | 3.160 | 0.803 | 0.054 | 4.302 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_006 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.105 | 0.127 | 2.804 | 0.124 | 0.026 | 6.245 | -0.981 | 0.153 | 2.558 | 0.887 | 0.055 | 4.267 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_007 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.795 | 0.064 | 3.950 | 0.047 | 0.026 | 6.245 | -0.748 | 0.090 | 3.338 | 0.812 | 0.054 | 4.299 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_008 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.891 | 0.094 | 3.254 | -0.131 | 0.026 | 6.245 | -1.022 | 0.120 | 2.886 | 0.827 | 0.054 | 4.292 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_009 | zebrafish | deltamethrin | percentage of time in left arm | NA | 1.183 | 0.073 | 3.711 | 0.467 | 0.026 | 6.245 | -0.716 | 0.098 | 3.190 | 1.100 | 0.058 | 4.168 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_010 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.578 | 0.048 | 4.570 | -0.301 | 0.026 | 6.245 | -0.878 | 0.074 | 3.688 | 0.689 | 0.053 | 4.345 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_011 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.424 | 0.079 | 3.557 | 0.100 | 0.026 | 6.245 | -0.323 | 0.105 | 3.091 | 0.344 | 0.051 | 4.439 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_012 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.983 | 0.058 | 4.169 | 0.009 | 0.026 | 6.245 | -0.973 | 0.083 | 3.467 | 1.161 | 0.058 | 4.137 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_013 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.229 | 0.047 | 4.601 | -0.259 | 0.026 | 6.245 | -0.488 | 0.073 | 3.704 | 0.243 | 0.050 | 4.456 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_014 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.698 | 0.088 | 3.366 | -0.239 | 0.026 | 6.245 | -0.937 | 0.114 | 2.963 | 0.635 | 0.053 | 4.364 | No | No |
| stungaru_2019 | stungaru_2019_exp_004 | stungaru_2019_exp_004_assay_015 | zebrafish | deltamethrin | percentage of time in left arm | NA | 0.079 | 0.027 | 6.046 | -0.281 | 0.026 | 6.245 | -0.360 | 0.053 | 4.344 | 0.107 | 0.050 | 4.469 | No | No |
| tamagno_2023 | tamagno_2023_exp_001 | tamagno_2023_exp_001_assay_001 | zebrafish | prallethrin | time in conspecific segment | NA | -0.235 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| tamagno_2023 | tamagno_2023_exp_002 | tamagno_2023_exp_002_assay_001 | zebrafish | prallethrin | time in conspecific segment | NA | -0.861 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| tamagno_2023 | tamagno_2023_exp_003 | tamagno_2023_exp_003_assay_001 | zebrafish | transfluthrin | time in conspecific segment | NA | -0.691 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| tamagno_2023 | tamagno_2023_exp_004 | tamagno_2023_exp_004_assay_001 | zebrafish | transfluthrin | time in conspecific segment | NA | -0.475 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | No | No |
| tamagno_2023 | tamagno_2023_exp_001 | tamagno_2023_exp_001_assay_002 | zebrafish | prallethrin | distance among fish in a shoal | change | -0.388 | 0.004 | 14.923 | 0.395 | 0.333 | 1.732 | 0.008 | 0.338 | 1.721 | 3.443 | 1.241 | 0.898 | No | No |
| tamagno_2023 | tamagno_2023_exp_002 | tamagno_2023_exp_002_assay_002 | zebrafish | prallethrin | distance among fish in a shoal | change | -0.393 | 0.004 | 15.372 | 0.339 | 0.333 | 1.732 | -0.053 | 0.338 | 1.721 | 3.630 | 1.323 | 0.869 | No | No |
| tamagno_2023 | tamagno_2023_exp_003 | tamagno_2023_exp_003_assay_002 | zebrafish | transfluthrin | distance among fish in a shoal | change | -0.343 | 0.005 | 14.785 | 0.369 | 0.333 | 1.732 | 0.026 | 0.338 | 1.720 | 3.028 | 1.073 | 0.965 | No | No |
| tamagno_2023 | tamagno_2023_exp_004 | tamagno_2023_exp_004_assay_002 | zebrafish | transfluthrin | distance among fish in a shoal | change | -0.404 | 0.004 | 16.017 | 0.259 | 0.333 | 1.732 | -0.144 | 0.337 | 1.722 | 3.953 | 1.477 | 0.823 | No | No |
| teather_2001 | teather_2001_exp_001 | teather_2001_exp_001_assay_001 | Japanese medaka | acrobat | number of approaches to female | NA | -0.399 | 0.057 | 4.173 | -0.377 | 0.053 | 4.359 | 0.022 | 0.110 | 3.014 | -0.502 | 0.103 | 3.114 | No | No |
| teather_2001 | teather_2001_exp_002 | teather_2001_exp_002_assay_001 | Japanese medaka | acrobat | number of approaches to female | NA | -1.095 | 0.047 | 4.608 | -1.289 | 0.053 | 4.359 | -0.195 | 0.100 | 3.166 | -1.186 | 0.118 | 2.916 | No | No |
| teather_2001 | teather_2001_exp_003 | teather_2001_exp_003_assay_001 | Japanese medaka | acrobat | number of approaches to female | NA | -1.291 | 0.114 | 2.957 | -0.730 | 0.053 | 4.359 | 0.561 | 0.167 | 2.447 | -1.208 | 0.118 | 2.908 | No | No |
| teather_2001 | teather_2001_exp_004 | teather_2001_exp_004_assay_001 | Japanese medaka | tattoo c | number of approaches to female | NA | -0.818 | 0.110 | 3.018 | -0.284 | 0.053 | 4.359 | 0.534 | 0.162 | 2.481 | -0.825 | 0.109 | 3.036 | No | No |
| teather_2001 | teather_2001_exp_005 | teather_2001_exp_005_assay_001 | Japanese medaka | tattoo c | number of approaches to female | NA | -0.531 | 0.117 | 2.925 | 0.045 | 0.053 | 4.359 | 0.575 | 0.170 | 2.429 | -0.526 | 0.103 | 3.109 | No | No |
| teather_2001 | teather_2001_exp_006 | teather_2001_exp_006_assay_001 | Japanese medaka | tattoo c | number of approaches to female | NA | -0.893 | 0.084 | 3.447 | -0.547 | 0.053 | 4.359 | 0.346 | 0.137 | 2.704 | -0.945 | 0.111 | 2.999 | No | No |
| yan_2023 | yan_2023_exp_001 | yan_2023_exp_001_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.893 | 0.024 | 6.402 | -0.693 | 0.067 | 3.873 | 0.200 | 0.091 | 3.314 | -1.839 | 0.178 | 2.371 | No | No |
| yan_2023 | yan_2023_exp_001 | yan_2023_exp_001_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.394 | 0.037 | 5.216 | -0.603 | 0.067 | 3.873 | -0.209 | 0.103 | 3.109 | -0.662 | 0.132 | 2.754 | No | No |
| yan_2023 | yan_2023_exp_002 | yan_2023_exp_002_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.676 | 0.029 | 5.900 | -0.347 | 0.067 | 3.873 | 0.329 | 0.095 | 3.238 | -1.397 | 0.156 | 2.536 | No | No |
| yan_2023 | yan_2023_exp_002 | yan_2023_exp_002_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.178 | 0.041 | 4.933 | -0.257 | 0.067 | 3.873 | -0.079 | 0.108 | 3.046 | -0.298 | 0.126 | 2.813 | No | No |
| yan_2023 | yan_2023_exp_003 | yan_2023_exp_003_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.773 | 0.025 | 6.279 | -0.541 | 0.067 | 3.873 | 0.232 | 0.092 | 3.296 | -1.621 | 0.166 | 2.454 | No | No |
| yan_2023 | yan_2023_exp_003 | yan_2023_exp_003_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.275 | 0.038 | 5.148 | -0.451 | 0.067 | 3.873 | -0.177 | 0.104 | 3.095 | -0.469 | 0.128 | 2.790 | No | No |
| yan_2023 | yan_2023_exp_004 | yan_2023_exp_004_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.156 | 0.033 | 5.529 | 0.814 | 0.067 | 3.873 | 0.970 | 0.099 | 3.172 | -0.315 | 0.127 | 2.811 | No | No |
| yan_2023 | yan_2023_exp_004 | yan_2023_exp_004_assay_002 | zebrafish | tebuconazole | number of contacts | NA | 0.183 | 0.043 | 4.803 | 0.514 | 0.067 | 3.873 | 0.331 | 0.110 | 3.015 | 0.293 | 0.126 | 2.813 | No | No |
| yan_2023 | yan_2023_exp_005 | yan_2023_exp_005_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.732 | 0.017 | 7.610 | -0.150 | 0.067 | 3.873 | 0.581 | 0.084 | 3.452 | -2.114 | 0.195 | 2.265 | No | No |
| yan_2023 | yan_2023_exp_005 | yan_2023_exp_005_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.392 | 0.028 | 5.987 | -0.450 | 0.067 | 3.873 | -0.057 | 0.095 | 3.252 | -0.776 | 0.134 | 2.728 | No | No |
| yan_2023 | yan_2023_exp_006 | yan_2023_exp_006_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.413 | 0.020 | 7.063 | 0.264 | 0.067 | 3.873 | 0.677 | 0.087 | 3.396 | -1.108 | 0.144 | 2.634 | No | No |
| yan_2023 | yan_2023_exp_006 | yan_2023_exp_006_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.074 | 0.031 | 5.709 | -0.035 | 0.067 | 3.873 | 0.039 | 0.097 | 3.205 | -0.145 | 0.125 | 2.825 | No | No |
| yan_2023 | yan_2023_exp_007 | yan_2023_exp_007_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.607 | 0.019 | 7.236 | -0.693 | 0.067 | 3.873 | -0.086 | 0.086 | 3.415 | -1.377 | 0.155 | 2.543 | No | No |
| yan_2023 | yan_2023_exp_007 | yan_2023_exp_007_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.480 | 0.012 | 9.180 | 0.032 | 0.067 | 3.873 | 0.512 | 0.079 | 3.568 | -1.632 | 0.167 | 2.450 | No | No |
| yan_2023 | yan_2023_exp_008 | yan_2023_exp_008_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.120 | 0.013 | 8.869 | -0.863 | 0.067 | 3.873 | -0.743 | 0.079 | 3.549 | -0.352 | 0.127 | 2.807 | No | No |
| yan_2023 | yan_2023_exp_008 | yan_2023_exp_008_assay_002 | zebrafish | tebuconazole | number of contacts | NA | 0.007 | 0.005 | 13.506 | -0.138 | 0.067 | 3.873 | -0.145 | 0.072 | 3.723 | 0.034 | 0.125 | 2.828 | No | No |
| yan_2023 | yan_2023_exp_009 | yan_2023_exp_009_assay_001 | zebrafish | tebuconazole | number of contacts | NA | -0.468 | 0.013 | 8.608 | -1.068 | 0.067 | 3.873 | -0.600 | 0.080 | 3.532 | -1.197 | 0.147 | 2.605 | No | No |
| yan_2023 | yan_2023_exp_009 | yan_2023_exp_009_assay_002 | zebrafish | tebuconazole | number of contacts | NA | -0.341 | 0.006 | 12.637 | -0.343 | 0.067 | 3.873 | -0.002 | 0.073 | 3.703 | -1.451 | 0.158 | 2.517 | No | No |
| yan_2023 | yan_2023_exp_001 | yan_2023_exp_001_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.820 | 0.015 | 8.181 | -0.853 | 0.067 | 3.873 | -0.033 | 0.082 | 3.501 | -2.020 | 0.189 | 2.302 | No | No |
| yan_2023 | yan_2023_exp_001 | yan_2023_exp_001_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.179 | 0.240 | 2.043 | -1.914 | 0.067 | 3.873 | -1.736 | 0.306 | 1.807 | -0.116 | 0.125 | 2.826 | No | No |
| yan_2023 | yan_2023_exp_002 | yan_2023_exp_002_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.556 | 0.052 | 4.396 | 0.315 | 0.067 | 3.873 | 0.871 | 0.118 | 2.906 | -0.986 | 0.140 | 2.671 | No | No |
| yan_2023 | yan_2023_exp_002 | yan_2023_exp_002_assay_004 | zebrafish | tebuconazole | contact time | NA | 0.086 | 0.276 | 1.902 | -0.746 | 0.067 | 3.873 | -0.832 | 0.343 | 1.707 | 0.058 | 0.125 | 2.828 | No | No |
| yan_2023 | yan_2023_exp_003 | yan_2023_exp_003_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.446 | 0.138 | 2.693 | 0.967 | 0.067 | 3.873 | 1.412 | 0.205 | 2.211 | -0.501 | 0.129 | 2.785 | No | No |
| yan_2023 | yan_2023_exp_003 | yan_2023_exp_003_assay_004 | zebrafish | tebuconazole | contact time | NA | 0.196 | 0.362 | 1.661 | -0.094 | 0.067 | 3.873 | -0.290 | 0.429 | 1.526 | 0.114 | 0.125 | 2.826 | No | No |
| yan_2023 | yan_2023_exp_004 | yan_2023_exp_004_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.130 | 0.030 | 5.760 | 0.553 | 0.067 | 3.873 | 0.683 | 0.097 | 3.214 | -0.268 | 0.126 | 2.816 | No | No |
| yan_2023 | yan_2023_exp_004 | yan_2023_exp_004_assay_004 | zebrafish | tebuconazole | contact time | NA | 0.077 | 0.041 | 4.926 | 0.245 | 0.067 | 3.873 | 0.167 | 0.108 | 3.045 | 0.131 | 0.125 | 2.825 | No | No |
| yan_2023 | yan_2023_exp_005 | yan_2023_exp_005_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.325 | 0.029 | 5.880 | 0.332 | 0.067 | 3.873 | 0.656 | 0.096 | 3.234 | -0.712 | 0.133 | 2.743 | No | No |
| yan_2023 | yan_2023_exp_005 | yan_2023_exp_005_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.117 | 0.040 | 5.001 | 0.024 | 0.067 | 3.873 | 0.141 | 0.107 | 3.062 | -0.203 | 0.126 | 2.821 | No | No |
| yan_2023 | yan_2023_exp_006 | yan_2023_exp_006_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.211 | 0.047 | 4.599 | 0.741 | 0.067 | 3.873 | 0.952 | 0.114 | 2.962 | -0.360 | 0.127 | 2.806 | No | No |
| yan_2023 | yan_2023_exp_006 | yan_2023_exp_006_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.003 | 0.058 | 4.140 | 0.433 | 0.067 | 3.873 | 0.436 | 0.125 | 2.828 | -0.005 | 0.125 | 2.828 | No | No |
| yan_2023 | yan_2023_exp_007 | yan_2023_exp_007_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.384 | 0.016 | 7.936 | -1.402 | 0.067 | 3.873 | -1.018 | 0.083 | 3.481 | -0.901 | 0.138 | 2.695 | No | No |
| yan_2023 | yan_2023_exp_007 | yan_2023_exp_007_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.135 | 0.005 | 14.541 | -0.363 | 0.067 | 3.873 | -0.228 | 0.071 | 3.743 | -0.664 | 0.132 | 2.754 | No | No |
| yan_2023 | yan_2023_exp_008 | yan_2023_exp_008_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.639 | 0.023 | 6.631 | -0.879 | 0.067 | 3.873 | -0.240 | 0.089 | 3.344 | -1.268 | 0.150 | 2.581 | No | No |
| yan_2023 | yan_2023_exp_008 | yan_2023_exp_008_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.390 | 0.012 | 9.288 | 0.160 | 0.067 | 3.873 | 0.550 | 0.078 | 3.575 | -1.341 | 0.153 | 2.556 | No | No |
| yan_2023 | yan_2023_exp_009 | yan_2023_exp_009_assay_003 | zebrafish | tebuconazole | contact time | NA | -0.406 | 0.019 | 7.309 | -0.956 | 0.067 | 3.873 | -0.550 | 0.085 | 3.422 | -0.906 | 0.138 | 2.694 | No | No |
| yan_2023 | yan_2023_exp_009 | yan_2023_exp_009_assay_004 | zebrafish | tebuconazole | contact time | NA | -0.157 | 0.008 | 11.491 | 0.083 | 0.067 | 3.873 | 0.240 | 0.074 | 3.670 | -0.629 | 0.131 | 2.761 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_001 | zebrafish | thiamethoxam | shoaling average speed | NA | -0.019 | 0.002 | 20.694 | 0.000 | 0.043 | 4.796 | 0.019 | 0.046 | 4.672 | -0.110 | 0.083 | 3.461 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_001 | zebrafish | thiamethoxam | shoaling average speed | NA | 0.054 | 0.002 | 23.701 | -0.241 | 0.043 | 4.796 | -0.295 | 0.045 | 4.701 | 0.368 | 0.085 | 3.435 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_001 | zebrafish | thiamethoxam | shoaling average speed | NA | 0.133 | 0.002 | 23.024 | -0.085 | 0.043 | 4.796 | -0.218 | 0.045 | 4.695 | 0.878 | 0.091 | 3.308 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_002 | zebrafish | thiamethoxam | average fish distance | change | 0.107 | 0.001 | 29.846 | -0.334 | 0.043 | 4.796 | -0.227 | 0.045 | 4.735 | -0.894 | 0.092 | 3.303 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_002 | zebrafish | thiamethoxam | average fish distance | change | 0.072 | 0.001 | 29.470 | -0.267 | 0.043 | 4.796 | -0.195 | 0.045 | 4.734 | -0.600 | 0.087 | 3.389 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_002 | zebrafish | thiamethoxam | average fish distance | change | 0.265 | 0.003 | 19.572 | 0.250 | 0.043 | 4.796 | 0.515 | 0.046 | 4.658 | -1.551 | 0.108 | 3.037 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_003 | zebrafish | thiamethoxam | maximum inter-fish difference | change | 0.033 | 0.000 | 85.677 | -0.014 | 0.043 | 4.796 | 0.019 | 0.044 | 4.788 | -0.800 | 0.090 | 3.333 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_003 | zebrafish | thiamethoxam | maximum inter-fish difference | change | 0.006 | 0.000 | 90.524 | -0.101 | 0.043 | 4.796 | -0.095 | 0.044 | 4.789 | -0.141 | 0.084 | 3.460 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_003 | zebrafish | thiamethoxam | maximum inter-fish difference | change | 0.040 | 0.000 | 58.776 | 0.562 | 0.043 | 4.796 | 0.602 | 0.044 | 4.780 | -0.680 | 0.088 | 3.368 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_004 | zebrafish | thiamethoxam | time spent in social zone | NA | 0.104 | 0.003 | 17.368 | -0.140 | 0.059 | 4.123 | -0.244 | 0.062 | 4.012 | 0.596 | 0.116 | 2.936 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_004 | zebrafish | thiamethoxam | time spent in social zone | NA | 0.335 | 0.003 | 18.422 | -0.081 | 0.059 | 4.123 | -0.417 | 0.062 | 4.024 | 2.107 | 0.173 | 2.406 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_004 | zebrafish | thiamethoxam | time spent in social zone | NA | 0.025 | 0.004 | 15.514 | 0.037 | 0.059 | 4.123 | 0.011 | 0.063 | 3.985 | 0.128 | 0.111 | 2.997 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_005 | zebrafish | thiamethoxam | time spent in social zone with familiar fish | NA | -0.109 | 0.006 | 13.076 | -0.375 | 0.059 | 4.123 | -0.266 | 0.065 | 3.932 | -0.456 | 0.114 | 2.962 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_005 | zebrafish | thiamethoxam | time spent in social zone with familiar fish | NA | 0.245 | 0.007 | 11.823 | 0.215 | 0.059 | 4.123 | -0.030 | 0.066 | 3.893 | 0.936 | 0.123 | 2.848 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_005 | zebrafish | thiamethoxam | time spent in social zone with familiar fish | NA | 0.312 | 0.006 | 13.372 | -0.017 | 0.059 | 4.123 | -0.329 | 0.064 | 3.940 | 1.402 | 0.138 | 2.688 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_006 | zebrafish | thiamethoxam | distance to familiar fish | change | -0.022 | 0.005 | 14.507 | 0.074 | 0.059 | 4.123 | 0.052 | 0.064 | 3.966 | 0.103 | 0.111 | 2.998 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_006 | zebrafish | thiamethoxam | distance to familiar fish | change | 0.330 | 0.008 | 11.145 | 0.143 | 0.059 | 4.123 | 0.473 | 0.067 | 3.867 | -1.264 | 0.133 | 2.739 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_006 | zebrafish | thiamethoxam | distance to familiar fish | change | 0.508 | 0.009 | 10.360 | 0.064 | 0.059 | 4.123 | 0.572 | 0.068 | 3.831 | -1.871 | 0.160 | 2.502 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_007 | zebrafish | thiamethoxam | number of transition to the attack zone | NA | 0.076 | 0.011 | 9.591 | -0.105 | 0.043 | 4.796 | -0.181 | 0.054 | 4.289 | 0.207 | 0.084 | 3.455 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_007 | zebrafish | thiamethoxam | number of transition to the attack zone | NA | 0.000 | 0.012 | 9.286 | -0.105 | 0.043 | 4.796 | -0.105 | 0.055 | 4.261 | 0.000 | 0.083 | 3.464 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_007 | zebrafish | thiamethoxam | number of transition to the attack zone | NA | 0.317 | 0.013 | 8.746 | 0.336 | 0.043 | 4.796 | 0.020 | 0.057 | 4.205 | 0.768 | 0.089 | 3.343 | No | No |
| yang_2023 | yang_2023_exp_001 | yang_2023_exp_001_assay_008 | zebrafish | thiamethoxam | biting time | NA | -0.184 | 0.032 | 5.621 | -0.479 | 0.043 | 4.796 | -0.296 | 0.075 | 3.648 | -0.284 | 0.084 | 3.447 | No | No |
| yang_2023 | yang_2023_exp_002 | yang_2023_exp_002_assay_008 | zebrafish | thiamethoxam | biting time | NA | -0.237 | 0.042 | 4.890 | -0.211 | 0.043 | 4.796 | 0.026 | 0.085 | 3.424 | -0.326 | 0.084 | 3.441 | No | No |
| yang_2023 | yang_2023_exp_003 | yang_2023_exp_003_assay_008 | zebrafish | thiamethoxam | biting time | NA | 0.397 | 0.042 | 4.887 | 0.424 | 0.043 | 4.796 | 0.027 | 0.085 | 3.423 | 0.532 | 0.086 | 3.405 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_001 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | 0.188 | 0.010 | 9.996 | -0.106 | 0.059 | 4.123 | -0.294 | 0.069 | 3.812 | 0.623 | 0.117 | 2.930 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_001 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | 0.180 | 0.010 | 9.907 | -0.089 | 0.059 | 4.123 | -0.269 | 0.069 | 3.807 | 0.591 | 0.116 | 2.937 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_001 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | 0.195 | 0.009 | 10.282 | -0.182 | 0.059 | 4.123 | -0.377 | 0.068 | 3.827 | 0.671 | 0.117 | 2.919 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_001 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | 0.169 | 0.011 | 9.343 | 0.046 | 0.059 | 4.123 | -0.124 | 0.070 | 3.772 | 0.518 | 0.115 | 2.951 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_001 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | 0.091 | 0.013 | 8.736 | 0.109 | 0.059 | 4.123 | 0.018 | 0.072 | 3.729 | 0.258 | 0.112 | 2.988 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_002 | zebrafish | atrazine | number of bites | NA | 0.059 | 0.010 | 10.045 | -0.272 | 0.059 | 4.123 | -0.331 | 0.069 | 3.814 | 0.194 | 0.112 | 2.993 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_002 | zebrafish | atrazine | number of bites | NA | 0.071 | 0.010 | 9.797 | -0.190 | 0.059 | 4.123 | -0.261 | 0.069 | 3.800 | 0.229 | 0.112 | 2.990 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_002 | zebrafish | atrazine | number of bites | NA | 0.063 | 0.008 | 11.173 | -0.682 | 0.059 | 4.123 | -0.745 | 0.067 | 3.868 | 0.234 | 0.112 | 2.990 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_002 | zebrafish | atrazine | number of bites | NA | 0.127 | 0.008 | 11.066 | -0.568 | 0.059 | 4.123 | -0.695 | 0.067 | 3.864 | 0.476 | 0.114 | 2.958 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_002 | zebrafish | atrazine | number of bites | NA | 0.084 | 0.009 | 10.446 | -0.372 | 0.059 | 4.123 | -0.456 | 0.068 | 3.835 | 0.290 | 0.112 | 2.984 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_003 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | -0.071 | 0.063 | 3.990 | -0.023 | 0.059 | 4.123 | 0.048 | 0.122 | 2.867 | -0.092 | 0.111 | 2.998 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_003 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | -0.250 | 0.049 | 4.506 | -0.467 | 0.059 | 4.123 | -0.217 | 0.108 | 3.042 | -0.353 | 0.113 | 2.977 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_003 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | -0.224 | 0.061 | 4.054 | -0.207 | 0.059 | 4.123 | 0.017 | 0.120 | 2.891 | -0.293 | 0.112 | 2.984 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_003 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | -0.221 | 0.041 | 4.926 | -0.707 | 0.059 | 4.123 | -0.486 | 0.100 | 3.162 | -0.335 | 0.113 | 2.979 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_003 | zebrafish | atrazine | time in stimulus zone close to mirror | NA | -0.610 | 0.063 | 3.979 | -0.556 | 0.059 | 4.123 | 0.053 | 0.122 | 2.863 | -0.746 | 0.119 | 2.901 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_004 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.182 | 0.084 | 3.451 | 0.038 | 0.059 | 4.123 | -0.143 | 0.143 | 2.647 | 0.205 | 0.112 | 2.992 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_004 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.167 | 0.088 | 3.374 | 0.075 | 0.059 | 4.123 | -0.092 | 0.147 | 2.611 | 0.184 | 0.112 | 2.994 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_004 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.200 | 0.074 | 3.682 | -0.110 | 0.059 | 4.123 | -0.310 | 0.133 | 2.747 | 0.246 | 0.112 | 2.989 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_004 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.578 | 0.066 | 3.898 | 0.084 | 0.059 | 4.123 | -0.494 | 0.125 | 2.833 | 0.788 | 0.120 | 2.890 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_004 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.450 | 0.077 | 3.601 | 0.201 | 0.059 | 4.123 | -0.248 | 0.136 | 2.712 | 0.535 | 0.115 | 2.948 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_005 | zebrafish | diuron | number of bites | NA | 0.311 | 0.254 | 1.985 | 0.171 | 0.059 | 4.123 | -0.140 | 0.313 | 1.789 | 0.201 | 0.112 | 2.992 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_005 | zebrafish | diuron | number of bites | NA | 0.381 | 0.303 | 1.816 | 0.428 | 0.059 | 4.123 | 0.047 | 0.362 | 1.662 | 0.217 | 0.112 | 2.991 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_005 | zebrafish | diuron | number of bites | NA | 0.713 | 0.220 | 2.130 | 0.392 | 0.059 | 4.123 | -0.322 | 0.279 | 1.893 | 0.500 | 0.115 | 2.954 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_005 | zebrafish | diuron | number of bites | NA | 0.611 | 0.240 | 2.040 | 0.406 | 0.059 | 4.123 | -0.205 | 0.299 | 1.829 | 0.401 | 0.113 | 2.970 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_005 | zebrafish | diuron | number of bites | NA | 0.307 | 0.237 | 2.056 | 0.082 | 0.059 | 4.123 | -0.225 | 0.295 | 1.840 | 0.209 | 0.112 | 2.992 | No | No |
| zaluski_2022 | zaluski_2022_exp_001 | zaluski_2022_exp_001_assay_006 | zebrafish | diuron | time in stimulus zone close to mirror | NA | -0.384 | 0.589 | 1.303 | 0.455 | 0.059 | 4.123 | 0.838 | 0.648 | 1.242 | -0.183 | 0.112 | 2.994 | No | No |
| zaluski_2022 | zaluski_2022_exp_002 | zaluski_2022_exp_002_assay_006 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.497 | 0.251 | 1.998 | 0.762 | 0.059 | 4.123 | 0.265 | 0.309 | 1.798 | 0.291 | 0.112 | 2.984 | No | No |
| zaluski_2022 | zaluski_2022_exp_003 | zaluski_2022_exp_003_assay_006 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.444 | 0.205 | 2.207 | 0.540 | 0.059 | 4.123 | 0.096 | 0.264 | 1.945 | 0.301 | 0.112 | 2.983 | No | No |
| zaluski_2022 | zaluski_2022_exp_004 | zaluski_2022_exp_004_assay_006 | zebrafish | diuron | time in stimulus zone close to mirror | NA | 0.445 | 0.205 | 2.207 | 0.541 | 0.059 | 4.123 | 0.096 | 0.264 | 1.945 | 0.301 | 0.112 | 2.983 | No | No |
| zaluski_2022 | zaluski_2022_exp_005 | zaluski_2022_exp_005_assay_006 | zebrafish | diuron | time in stimulus zone close to mirror | NA | -2.146 | 0.746 | 1.158 | -1.171 | 0.059 | 4.123 | 0.975 | 0.805 | 1.115 | -0.902 | 0.122 | 2.858 | No | No |
| zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp_001_assay_001 | marine medaka | diuron | time spent on the side closest to the mirror | NA | -0.148 | 0.029 | 5.832 | -0.757 | 0.048 | 4.583 | -0.609 | 0.077 | 3.603 | -0.245 | 0.092 | 3.304 | No | No |
| zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp_002_assay_001 | marine medaka | diuron | time spent on the side closest to the mirror | NA | -0.302 | 0.039 | 5.056 | -0.463 | 0.048 | 4.583 | -0.161 | 0.087 | 3.395 | -0.433 | 0.093 | 3.278 | No | No |
| zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp_003_assay_001 | marine medaka | diuron | time spent on the side closest to the mirror | NA | -0.450 | 0.025 | 6.376 | -1.686 | 0.048 | 4.583 | -1.236 | 0.072 | 3.721 | -0.701 | 0.096 | 3.219 | No | No |
| zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp_004_assay_001 | marine medaka | diuron | time spent on the side closest to the mirror | NA | -0.152 | 0.034 | 5.391 | -0.482 | 0.048 | 4.583 | -0.330 | 0.082 | 3.492 | -0.236 | 0.092 | 3.305 | No | No |
| zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp_001_assay_002 | marine medaka | diuron | mirror biting frequency | NA | 0.116 | 0.023 | 6.551 | 0.234 | 0.048 | 4.583 | 0.118 | 0.071 | 3.755 | 0.222 | 0.091 | 3.306 | No | No |
| zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp_002_assay_002 | marine medaka | diuron | mirror biting frequency | NA | -0.119 | 0.023 | 6.548 | 0.000 | 0.048 | 4.583 | 0.119 | 0.071 | 3.754 | -0.231 | 0.092 | 3.306 | No | No |
| zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp_003_assay_002 | marine medaka | diuron | mirror biting frequency | NA | -0.189 | 0.016 | 8.000 | -0.517 | 0.048 | 4.583 | -0.327 | 0.063 | 3.976 | -0.433 | 0.093 | 3.278 | No | No |
| zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp_004_assay_002 | marine medaka | diuron | mirror biting frequency | NA | 0.040 | 0.013 | 8.800 | -0.642 | 0.048 | 4.583 | -0.682 | 0.061 | 4.065 | 0.106 | 0.091 | 3.314 | No | No |
| zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp_001_assay_003 | marine medaka | diuron | cluster score | NA | 0.183 | 0.161 | 2.490 | 0.369 | 0.200 | 2.236 | 0.186 | 0.361 | 1.664 | 0.237 | 0.336 | 1.726 | No | No |
| zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp_002_assay_003 | marine medaka | diuron | cluster score | NA | -0.069 | 0.075 | 3.647 | -1.046 | 0.200 | 2.236 | -0.977 | 0.275 | 1.906 | -0.131 | 0.334 | 1.730 | No | No |
| zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp_003_assay_003 | marine medaka | diuron | cluster score | NA | -0.290 | 0.128 | 2.790 | -0.315 | 0.200 | 2.236 | -0.025 | 0.328 | 1.745 | -0.422 | 0.341 | 1.713 | No | No |
| zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp_004_assay_003 | marine medaka | diuron | cluster score | NA | -0.532 | 0.140 | 2.676 | -0.475 | 0.200 | 2.236 | 0.057 | 0.340 | 1.716 | -0.728 | 0.355 | 1.677 | No | No |
| zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp_001_assay_004 | marine medaka | diuron | time spent on the side closest to the seperator | NA | -0.043 | 0.016 | 7.849 | -0.056 | 0.053 | 4.359 | -0.013 | 0.069 | 3.811 | -0.103 | 0.100 | 3.160 | No | No |
| zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp_002_assay_004 | marine medaka | diuron | time spent on the side closest to the seperator | NA | -0.149 | 0.016 | 8.031 | -0.210 | 0.053 | 4.359 | -0.061 | 0.068 | 3.831 | -0.368 | 0.102 | 3.136 | No | No |
| zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp_003_assay_004 | marine medaka | diuron | time spent on the side closest to the seperator | NA | -0.297 | 0.019 | 7.250 | -0.161 | 0.053 | 4.359 | 0.137 | 0.072 | 3.736 | -0.670 | 0.106 | 3.077 | No | No |
| zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp_004_assay_004 | marine medaka | diuron | time spent on the side closest to the seperator | NA | -0.015 | 0.022 | 6.715 | 0.250 | 0.053 | 4.359 | 0.265 | 0.075 | 3.656 | -0.031 | 0.100 | 3.162 | No | No |
| zhou_2021 | zhou_2021_exp_001 | zhou_2021_exp_001_assay_005 | marine medaka | diuron | interaction frequency | NA | 0.312 | 0.007 | 12.196 | 0.784 | 0.053 | 4.359 | 0.473 | 0.059 | 4.105 | 1.085 | 0.115 | 2.953 | No | No |
| zhou_2021 | zhou_2021_exp_002 | zhou_2021_exp_002_assay_005 | marine medaka | diuron | interaction frequency | NA | 0.349 | 0.008 | 11.287 | 0.926 | 0.053 | 4.359 | 0.577 | 0.060 | 4.066 | 1.098 | 0.115 | 2.948 | No | No |
| zhou_2021 | zhou_2021_exp_003 | zhou_2021_exp_003_assay_005 | marine medaka | diuron | interaction frequency | NA | 0.153 | 0.007 | 11.814 | 0.669 | 0.053 | 4.359 | 0.516 | 0.060 | 4.089 | 0.538 | 0.104 | 3.107 | No | No |
| zhou_2021 | zhou_2021_exp_004 | zhou_2021_exp_004_assay_005 | marine medaka | diuron | interaction frequency | NA | 0.062 | 0.008 | 11.460 | 0.619 | 0.053 | 4.359 | 0.557 | 0.060 | 4.074 | 0.217 | 0.101 | 3.153 | No | No |
# Plot the distribution of effect size estimates (lnRR)
lnRR_dist_plot <- effect_size_metrics_set_kable %>%
ggplot(aes(lnRR)) + geom_histogram(fill = RColorBrewer::brewer.pal(n = 8, name = "Set2")[2],
col = "black", binwidth = 0.1, alpha = 0.4) + theme_bw() + theme(legend.position = "none",
plot.title = element_text(face = "bold", hjust = 0.5), axis.title.x = element_text(face = "bold"),
axis.title.y = element_text(face = "bold"), axis.text.x = element_text(color = "black"),
axis.text.y = element_text(color = "black"), axis.ticks = element_line(color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
labs(caption = "Distribution of Effect Size Estimates (lnRR)", x = "lnRR", y = "Frequency")
print(lnRR_dist_plot)
# Plot the distribution of effect size estimates (lnVR)
lnVR_dist_plot <- effect_size_metrics_set_kable %>%
ggplot(aes(lnCVR)) + geom_histogram(fill = RColorBrewer::brewer.pal(n = 8, name = "Set2")[3],
col = "black", binwidth = 0.1, alpha = 0.4) + theme_bw() + theme(legend.position = "none",
plot.title = element_text(face = "bold", hjust = 0.5), axis.title.x = element_text(face = "bold"),
axis.title.y = element_text(face = "bold"), axis.text.x = element_text(color = "black"),
axis.text.y = element_text(color = "black"), axis.ticks = element_line(color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic")) +
labs(caption = "Distribution of Effect Size Estimates (lnVR)", x = "lnVR", y = "Frequency")
print(lnVR_dist_plot)
Dependent effect size estimates
Create phylogentic tree
We used the rotl package (https://peerj.com/preprints/1471/) to retrieve synthetic species tree from Open Tree of Life (https://opentreeoflife.org/).
data <- as.data.frame(data)
data$species_latin = as.factor(data$species_latin)
taxa <- tnrs_match_names(names = levels(data$species_latin), context = "Animals") # Match species names to the Open Tree of Life taxonomy
kable(taxa) # Display matched species, ensuring each species has a unique match in the Open Tree of Life| search_string | unique_name | approximate_match | score | ott_id | is_synonym | flags | number_matches |
|---|---|---|---|---|---|---|---|
| alburnus alburnus | Alburnus alburnus | FALSE | 1 | 957577 | FALSE | 1 | |
| danio rerio | Danio rerio | FALSE | 1 | 1005914 | FALSE | 1 | |
| jenynsia multidentata | Jenynsia multidentata | FALSE | 1 | 834785 | FALSE | 1 | |
| luciobarbus bocagei | Luciobarbus bocagei | FALSE | 1 | 134749 | FALSE | 1 | |
| oreochromis niloticus | Oreochromis niloticus | FALSE | 1 | 288063 | FALSE | sibling_higher | 1 |
| oryzias latipes | Oryzias latipes | FALSE | 1 | 942673 | FALSE | 1 | |
| oryzias melastigma | Oryzias melastigma | FALSE | 1 | 179491 | FALSE | 2 | |
| poecilia latipinna | Poecilia latipinna | FALSE | 1 | 998174 | FALSE | 1 | |
| poecilia reticulata | Poecilia reticulata | FALSE | 1 | 312452 | FALSE | 1 | |
| salmo trutta | Salmo trutta | FALSE | 1 | 688332 | FALSE | 1 |
taxa$unique_name <- gsub(" ", "_", taxa$unique_name) # Replace spaces in species names with underscores
phylo_tree <- tol_induced_subtree(ott_ids = taxa$ott_id, label_format = "name") # Generate a phylogenetic tree based on the Open Tree of Life taxonomyott_in_tree <- ott_id(taxa)[is_in_tree(ott_id(taxa))] # Ensure all identifiers are present in the taxonomy
phylo_tree <- tol_induced_subtree(ott_ids = ott_in_tree) # Generate a phylogenetic tree including all species present in the taxonomy## [1] TRUE# Plot for the phylogenetic tree
plot(phylo_tree,
cex= 1, #font size
label.offset =.1,
no.margin = TRUE)
# Compute branch length
phylo_branched <- compute.brlen(phylo_tree, method = "Grafen", power = 1) # compute branch lengths using Grafen's method
phylo_branched$tip.label <- strip_ott_ids(phylo_branched$tip.label, remove_underscores = FALSE) # remove ott ID from species name to match it to the data set
phylo_matrix <- vcv(phylo_branched, cor = T) # Generate variance covariance matrix to correlate species relatedness
data <- as.data.frame(data)
# Convert species_latin to lowercase
data <- mutate(data, search_string = tolower(species_latin))
data <- left_join(data, select(taxa, search_string, unique_name, ott_id), by = "search_string") # Join data sets
data <- data[data$unique_name %in% phylo_branched$tip.label, ] # Check that species names are well matched with the phylogenetic tree
data$phylogeny <- data$unique_name # Rename 'unique_name' to 'phylogeny' for the modelsVariance covariance matrices
# account for sampling covariance, assuming effect size within studies are
# correlated with rho = 0.5
#------------------------------lnRR------------------------------#
data <- data[!is.na(data$lnRRv), ]
lnRRVCV <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id, data = data,
rho = 0.5)
lnRRVCV2 <- metafor::vcalc(vi = lnRRv, cluster = exp2_id, obs = assay_id, data = data,
rho = 0.5) # Sensitivity analysis with alternative VCV
#------------------------------lnVR------------------------------#
data <- data[!is.na(data$lnVRv), ]
lnVRVCV <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id, data = data,
rho = 0.5)
lnVRVCV2 <- metafor::vcalc(vi = lnVRv, cluster = exp2_id, obs = assay2_id, data = data,
rho = 0.5) # Sensitivity analysis with alternative VCV
#------------------------------lnCVR------------------------------#
data <- data[!is.na(data$lnCVRv), ]
lnCVRVCV <- metafor::vcalc(vi = lnCVRv, cluster = exp_id, obs = assay_id, data = data,
rho = 0.5)
#------------------------------SMD------------------------------#
data <- data[!is.na(data$SMDv), ]
SMDVCV <- metafor::vcalc(vi = SMDv, cluster = exp_id, obs = assay_id, data = data,
rho = 0.5)Selection of random-effect structure
Select the “most appropriate” structure for the subsequent statistical modelling.
The potential random effect were:
- Observation (assay_id) - A unique id for each pairwise comparison for effect size calculation
- Cohort (exp_id) - A unique id for each exposure group in each primary study
- Study (study_id) - A unique id for each included primary study
- Pesticide (pesticide) - Each pesticide used in the primary study
- Species (species) - Each species used in the primary study
- Phylogeny (phylogeny) - The phylogenetic relatedness for each species in the primary studies
We start from fitting a null model without including the above random effects candidates as the default reduced model, and build upon more complex models by adding random-effects a candidate one time. We use the likelihood ratio test to compare the quality of two nested models in terms of information criteria indices (AIC, BIC, AICc).
Null model with no random effects (lnRR)
# fit a null model as default model
null_mod_lnRR <- rma.mv(yi = lnRR, V = lnRRVCV, method = "ML", test = "t", data = data,
sparse = TRUE) # Use ML to compare information criteria
summary(null_mod_lnRR)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -2076.4225 5125.7373 4154.8450 4158.9498 4154.8539
##
## Variance Components: none
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0306 0.0035 -8.7653 447 <.0001 -0.0375 -0.0238 ***
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Add assay_id as a random effect and compare with the null model (lnRR)
mod_lnRR.assay_id <- rma.mv(yi = lnRR, V = lnRRVCV, random = ~1 | assay_id, method = "ML",
test = "t", data = data, sparse = T)
summary(mod_lnRR.assay_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -218.8077 1410.5078 441.6154 449.8250 441.6424
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2 0.0847 0.2910 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.1010 0.0196 -5.1398 447 <.0001 -0.1396 -0.0624 ***
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 2 441.6154 449.8250 441.6424 -218.8077 5125.7373
## Reduced 1 4154.8450 4158.9498 4154.8539 -2076.4225 3715.2295 <.0001 5125.7373Adding assay_id as a random effect improved model quality
Add study_id as a random effect to the above better model (that used obs_ID a random effect) (lnRR)
mod_lnRR.assay_id.study_id <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id), method = "ML", test = "t", data = data, sparse = T)
summary(mod_lnRR.assay_id.study_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -174.0307 1320.9537 354.0614 366.3757 354.1154
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0647 0.2543 37 no study_id
## sigma^2.2 0.0599 0.2448 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.1189 0.0485 -2.4535 447 0.0145 -0.2142 -0.0237 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 3 354.0614 366.3757 354.1154 -174.0307 5125.7373
## Reduced 2 441.6154 449.8250 441.6424 -218.8077 89.5541 <.0001 5125.7373Adding study study_id as a random effect improved model quality
Add exp_id as a random effect to the above model (that used assay_id and study_id as random effets) (lnRR)
mod_lnRR.assay_id.study_id.exp_id <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 |
study_id, ~1 | exp_id, ~1 | assay_id), method = "ML", test = "t", data = data,
sparse = T)
summary(mod_lnRR.assay_id.study_id.exp_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -174.0307 1320.9537 356.0614 372.4805 356.1516
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0647 0.2543 37 no study_id
## sigma^2.2 0.0000 0.0000 111 no exp_id
## sigma^2.3 0.0599 0.2448 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.1189 0.0485 -2.4535 447 0.0145 -0.2142 -0.0237 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 4 356.0614 372.4805 356.1516 -174.0307 5125.7373
## Reduced 3 354.0614 366.3757 354.1154 -174.0307 0.0000 1.0000 5125.7373Adding study exp_id as a random effect did not improve model quality and does not explain varation in the model
Add species as a random effect to the better model (that used assay_id and study_id as random effets) (lnRR)
mod_lnRR.assay_id.study_id.species <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin), method = "ML", test = "t", data = data,
sparse = T)
summary(mod_lnRR.assay_id.study_id.species)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -171.7538 1316.3998 351.5075 367.9267 351.5978
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0543 0.2331 37 no study_id
## sigma^2.2 0.0589 0.2427 448 no assay_id
## sigma^2.3 0.0454 0.2130 10 no species_latin
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2467 0.1001 -2.4637 447 0.0141 -0.4436 -0.0499 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 4 351.5075 367.9267 351.5978 -171.7538 5125.7373
## Reduced 3 354.0614 366.3757 354.1154 -174.0307 4.5538 0.0328 5125.7373## I2_Total I2_study_id I2_assay_id I2_species_latin
## 97.07031 33.24977 36.04941 27.77113Adding study species as a random effect did not improve model quality however is biologically relevant and thus we included in the model
Add phylogeny as a random effect to the better model (that used assay_id , study_id and species as random effects) (lnRR)
mod_lnRR.assay_id.study_id.species.phylogeny <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | phylogeny), method = "ML",
test = "t", data = data, sparse = T, R = list(phylogeny = phylo_matrix))
summary(mod_lnRR.assay_id.study_id.species.phylogeny)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -171.7538 1316.3998 353.5075 374.0315 353.6433
##
## Variance Components:
##
## estim sqrt nlvls fixed factor R
## sigma^2.1 0.0543 0.2331 37 no study_id no
## sigma^2.2 0.0589 0.2427 448 no assay_id no
## sigma^2.3 0.0454 0.2130 10 no species_latin no
## sigma^2.4 0.0000 0.0000 10 no phylogeny yes
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2467 0.1001 -2.4637 447 0.0141 -0.4436 -0.0499 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## mod_lnRR.assay_id.study_id.species
## logLik: -171.7538
## deviance: 1316.3998
## AIC: 351.5075
## BIC: 367.9267
## AICc: 351.5978
## mod_lnRR.assay_id.study_id.species.phylogeny
## logLik: -171.7538
## deviance: 1316.3998
## AIC: 353.5075
## BIC: 374.0315
## AICc: 353.6433## I2_Total I2_study_id I2_assay_id I2_species_latin
## 9.707031e+01 3.324977e+01 3.604941e+01 2.777113e+01
## I2_phylogeny
## 3.442931e-07Adding phylogeny as a random effect did not improve model quality and does not explain any varation and was thus removed from the model
Add pesticide as a random effect to the above model (that used assay_id , study_id, species and phylogeny as random effects) (lnRR)
mod_lnRR.assay_id.study_id.species.pesticide <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "ML",
test = "t", data = data, sparse = T)
summary(mod_lnRR.assay_id.study_id.species.pesticide)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -171.1338 1315.1600 352.2677 372.7916 352.4034
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0520 0.2280 37 no study_id
## sigma^2.2 0.0583 0.2414 448 no assay_id
## sigma^2.3 0.0478 0.2187 10 no species_latin
## sigma^2.4 0.0076 0.0873 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2609 0.1040 -2.5094 447 0.0124 -0.4652 -0.0566 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 5 352.2677 372.7916 352.4034 -171.1338 5125.7373
## Reduced 4 351.5075 367.9267 351.5978 -171.7538 1.2398 0.2655 5125.7373## I2_Total I2_study_id I2_assay_id I2_species_latin
## 97.193337 30.486413 34.179792 28.056365
## I2_pesticide
## 4.470767Adding pesticide as a random effect did not improve model quality but explains varation in the dataset
Null model with no random effects (lnVR)
# fit a null model as default model
null_mod_lnVR <- rma.mv(yi = lnVR, V = lnVRVCV, method = "ML", test = "t", data = data,
sparse = TRUE) # Use ML to compare information criteria
summary(null_mod_lnVR)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -1523.4543 3617.6450 3048.9087 3053.0135 3048.9176
##
## Variance Components: none
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0862 0.0187 -4.6111 447 <.0001 -0.1229 -0.0494 ***
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Add assay_id as a random effect and compare with the null model (lnVR)
mod_lnVR.assay_id <- rma.mv(yi = lnVR, V = lnVRVCV, random = ~1 | assay_id, method = "ML",
test = "t", data = data, sparse = T)
summary(mod_lnVR.assay_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -393.0636 1356.8635 790.1271 798.3367 790.1541
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2 0.2591 0.5090 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0520 0.0329 -1.5825 447 0.1143 -0.1166 0.0126
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 2 790.1271 798.3367 790.1541 -393.0636 3617.6450
## Reduced 1 3048.9087 3053.0135 3048.9176 -1523.4543 2260.7815 <.0001 3617.6450Adding assay_id as a random effect improved model quality
Add study_id as a random effect to the above better model (that used assay_id a random effect) (lnVR)
mod_lnVR.assay_id.study_id <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id), method = "ML", test = "t", data = data, sparse = T)
summary(mod_lnVR.assay_id.study_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -391.7199 1354.1762 789.4398 801.7542 789.4939
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0157 0.1252 37 no study_id
## sigma^2.2 0.2513 0.5013 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0552 0.0420 -1.3136 447 0.1897 -0.1378 0.0274
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 3 789.4398 801.7542 789.4939 -391.7199 3617.6450
## Reduced 2 790.1271 798.3367 790.1541 -393.0636 2.6873 0.1012 3617.6450Adding study_id as a random effect improved model quality
Add exp_id as a random effect to the above better model (that used assay_id and study_id as random effets) (lnVR)
mod_lnVR.assay_id.study_id.exp_id <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 |
study_id, ~1 | exp_id, ~1 | assay_id), method = "ML", test = "t", data = data,
sparse = T)
summary(mod_lnVR.assay_id.study_id.exp_id)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -391.7199 1354.1762 791.4398 807.8590 791.5301
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0157 0.1252 37 no study_id
## sigma^2.2 0.0000 0.0000 111 no exp_id
## sigma^2.3 0.2513 0.5013 448 no assay_id
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0552 0.0420 -1.3136 447 0.1897 -0.1378 0.0274
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 4 791.4398 807.8590 791.5301 -391.7199 3617.6450
## Reduced 3 789.4398 801.7542 789.4939 -391.7199 0.0000 1.0000 3617.6450Adding exp_id as a random effect did not improve model quality
Add species as a random effect to the above better model (that used assay_id and study_id as random effets) (lnVR)
mod_lnVR.assay_id.study_id.species <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin), method = "ML", test = "t", data = data,
sparse = T)
summary(mod_lnVR.assay_id.study_id.species)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -391.7199 1354.1762 791.4398 807.8590 791.5301
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0157 0.1252 37 no study_id
## sigma^2.2 0.2513 0.5013 448 no assay_id
## sigma^2.3 0.0000 0.0000 10 no species_latin
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0552 0.0420 -1.3136 447 0.1897 -0.1378 0.0274
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 4 791.4398 807.8590 791.5301 -391.7199 3617.6450
## Reduced 3 789.4398 801.7542 789.4939 -391.7199 0.0000 1.0000 3617.6450Adding study species as a random effect did not improve model quality however is biologically relevant and thus we included in the model
Add phylogeny as a random effect to the above better model (that used assay_id , study_id and species as random effects) (lnVR)
mod_lnVR.assay_id.study_id.species.phylogeny <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | phylogeny), method = "ML",
test = "t", data = data, sparse = T, R = list(phylogeny = phylo_matrix))
summary(mod_lnVR.assay_id.study_id.species.phylogeny)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -391.7199 1354.1762 793.4398 813.9638 793.5756
##
## Variance Components:
##
## estim sqrt nlvls fixed factor R
## sigma^2.1 0.0157 0.1252 37 no study_id no
## sigma^2.2 0.2513 0.5013 448 no assay_id no
## sigma^2.3 0.0000 0.0000 10 no species_latin no
## sigma^2.4 0.0000 0.0000 10 no phylogeny yes
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0552 0.0420 -1.3136 447 0.1897 -0.1378 0.0274
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1##
## df AIC BIC AICc logLik LRT pval QE
## Full 5 793.4398 813.9638 793.5756 -391.7199 3617.6450
## Reduced 4 791.4398 807.8590 791.5301 -391.7199 0.0000 0.9999 3617.6450Adding phylogeny as a random effect did not improve model quality however is biologically relevant and thus we included in the model
Add pesticide as a random effect to the above better model (that used assay_id , study_id, species and phylogeny as random effects) (lnVR)
mod_lnVR.assay_id.study_id.species.phylogeny.pesticide <- rma.mv(yi = lnCVR, V = lnCVRVCV,
random = list(~1 | study_id, ~1 | assay_id, ~1 | species_latin, ~1 | phylogeny,
~1 | pesticide), method = "ML", test = "t", data = data, sparse = T, R = list(phylogeny = phylo_matrix))
summary(mod_lnVR.assay_id.study_id.species.phylogeny.pesticide)##
## Multivariate Meta-Analysis Model (k = 448; method: ML)
##
## logLik Deviance AIC BIC AICc
## -348.6810 986.4516 709.3620 733.9907 709.5525
##
## Variance Components:
##
## estim sqrt nlvls fixed factor R
## sigma^2.1 0.0212 0.1455 37 no study_id no
## sigma^2.2 0.1591 0.3988 448 no assay_id no
## sigma^2.3 0.0000 0.0000 10 no species_latin no
## sigma^2.4 0.0221 0.1486 10 no phylogeny yes
## sigma^2.5 0.0030 0.0547 30 no pesticide no
##
## Test for Heterogeneity:
## Q(df = 447) = 1797.4539, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## 0.0637 0.1080 0.5897 447 0.5557 -0.1485 0.2758
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1Adding pesticide as a random effect did not improve model quality, and the number of levels overlaps significantly with the study.
Intercept only meta-analysis model
Intercept only model (lnRR)
# Model
lnRR_intercept_only <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t",
data = data, sparse = T)
# Summary statistics
summary(lnRR_intercept_only)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -169.3896 338.7792 348.7792 369.2920 348.9153
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0532 0.2308 37 no study_id
## sigma^2.2 0.0582 0.2412 448 no assay_id
## sigma^2.3 0.0613 0.2477 10 no species_latin
## sigma^2.4 0.0080 0.0897 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2669 0.1119 -2.3862 447 0.0174 -0.4868 -0.0471 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_intercept_only, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.2669384 -0.4867913 -0.04708555 -1.131056 0.597179## I2_Total I2_study_id I2_assay_id I2_species_latin
## 97.420978 28.689981 31.340099 33.054406
## I2_pesticide
## 4.336491# Given poitn estimate of lnRR
lnRR_point <- -0.2669
# Calculate the percentage change
lnRR_percentage_change <- (1 - exp(lnRR_point)) * 100
lnRR_percentage_change## [1] 23.42504# orchaRd plot
orchaRd::orchard_plot(lnRR_intercept_only, group = "study_id", xlab = "lnRR", data = data,
k.pos = "right", colour = FALSE, fill = TRUE, trunk.size = 4, branch.size = 2,
twig.size = 1)
Intercept only model (lnVR)
# Model
lnVR_intercept_only <- rma.mv(yi = lnVR, V = lnCVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t",
data = data, sparse = T)
# Summary statistics
summary(lnVR_intercept_only)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -392.5921 785.1842 795.1842 815.6970 795.3202
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0103 0.1017 37 no study_id
## sigma^2.2 0.2151 0.4638 448 no assay_id
## sigma^2.3 0.0000 0.0000 10 no species_latin
## sigma^2.4 0.0000 0.0001 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 2147.8880, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0728 0.0418 -1.7409 447 0.0824 -0.1549 0.0094 .
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_intercept_only, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.07277361 -0.1549259 0.009378667 -1.00954 0.8639932## I2_Total I2_study_id I2_assay_id I2_species_latin
## 7.057998e+01 3.237741e+00 6.734224e+01 5.436082e-11
## I2_pesticide
## 9.295015e-07# Given point estimate of lnRR
lnVR_point <- -0.0728
# Calculate the percentage change
lnVR_percentage_change <- (1 - exp(lnVR_point)) * 100
lnVR_percentage_change## [1] 7.021323# orchaRd plot
orchaRd::orchard_plot(lnVR_intercept_only, group = "study_id", xlab = "lnVR", data = data,
k.pos = "right", colour = FALSE, fill = TRUE, trunk.size = 4, branch.size = 2,
twig.size = 1)
Single moderator meta-regression
Behaviour characteristics
Moderate by behaviour class (lnRR)
# Model
lnRR_mod_behaviour_class <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behaviour_measured_standardised -
1, method = "REML", test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_behaviour_class)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -157.6271 315.2542 331.2542 364.0208 331.5853
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0491 0.2216 37 no study_id
## sigma^2.2 0.0541 0.2326 448 no assay_id
## sigma^2.3 0.0622 0.2494 10 no species_latin
## sigma^2.4 0.0059 0.0770 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 444) = 3709.4943, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 444) = 7.1848, p-val < .0001
##
## Model Results:
##
## estimate se tval
## behaviour_measured_standardisedaggression -0.1251 0.1160 -1.0779
## behaviour_measured_standardisedcollective behaviour -0.1788 0.1218 -1.4675
## behaviour_measured_standardisedcourtship -0.4280 0.1173 -3.6501
## behaviour_measured_standardisedsociality -0.1530 0.1198 -1.2768
## df pval ci.lb
## behaviour_measured_standardisedaggression 444 0.2817 -0.3531
## behaviour_measured_standardisedcollective behaviour 444 0.1430 -0.4183
## behaviour_measured_standardisedcourtship 444 0.0003 -0.6585
## behaviour_measured_standardisedsociality 444 0.2023 -0.3886
## ci.ub
## behaviour_measured_standardisedaggression 0.1030
## behaviour_measured_standardisedcollective behaviour 0.0607
## behaviour_measured_standardisedcourtship -0.1976 ***
## behaviour_measured_standardisedsociality 0.0825
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_behaviour_class, mod = "behaviour_measured_standardised", data = data,
group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Aggression -0.1250780 -0.3531254 0.10296951 -0.9698693 0.7197134
## 2 Collective behaviour -0.1788090 -0.4182769 0.06065887 -1.0267546 0.6691365
## 3 Courtship -0.4280461 -0.6585198 -0.19757233 -1.2734956 0.4174035
## 4 Sociality -0.1530223 -0.3885554 0.08251080 -0.9998650 0.6938205## R2_marginal R2_conditional
## 0.07060053 0.96783006# Given point estimate of lnRR
courtship_lnRR_point <- -0.428
# Calculate the percentage change
courtship_lnRR_percentage_change <- (1 - exp(courtship_lnRR_point)) * 100
courtship_lnRR_percentage_change## [1] 34.81886# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_behaviour_class, group = "pesticide_chemical_class",
xlab = "lnRR", data = data, mod = "behaviour_measured_standardised", k.pos = "right",
colour = TRUE, fill = TRUE, trunk.size = 4, branch.size = 2, twig.size = 1)
Moderate by behaviour class (lnVR)
# Model
lnVR_mod_behaviour_class <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behaviour_measured_standardised -
1, method = "REML", test = "t", data = data, sparse = T)
# Summary statistics
summary(lnVR_mod_behaviour_class)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -386.9398 773.8797 789.8797 822.6463 790.2107
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0287 0.1693 37 no study_id
## sigma^2.2 0.2439 0.4938 448 no assay_id
## sigma^2.3 0.0217 0.1472 10 no species_latin
## sigma^2.4 0.0000 0.0001 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 444) = 3505.1296, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 444) = 1.3083, p-val = 0.2660
##
## Model Results:
##
## estimate se tval
## behaviour_measured_standardisedaggression -0.0470 0.1060 -0.4436
## behaviour_measured_standardisedcollective behaviour -0.0481 0.1162 -0.4135
## behaviour_measured_standardisedcourtship -0.1674 0.1040 -1.6092
## behaviour_measured_standardisedsociality 0.0743 0.1144 0.6493
## df pval ci.lb
## behaviour_measured_standardisedaggression 444 0.6576 -0.2554
## behaviour_measured_standardisedcollective behaviour 444 0.6794 -0.2765
## behaviour_measured_standardisedcourtship 444 0.1083 -0.3718
## behaviour_measured_standardisedsociality 444 0.5165 -0.1505
## ci.ub
## behaviour_measured_standardisedaggression 0.1613
## behaviour_measured_standardisedcollective behaviour 0.1804
## behaviour_measured_standardisedcourtship 0.0370
## behaviour_measured_standardisedsociality 0.2990
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_behaviour_class, mod = "behaviour_measured_standardised", data = data,
group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Aggression -0.04702923 -0.2554049 0.16134647 -1.133221 1.0391626
## 2 Collective behaviour -0.04806303 -0.2764918 0.18036572 -1.138280 1.0421535
## 3 Courtship -0.16737461 -0.3717935 0.03704429 -1.252814 0.9180651
## 4 Sociality 0.07425841 -0.1504989 0.29901568 -1.015195 1.1637115## R2_marginal R2_conditional
## 0.02163905 0.99999998# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_behaviour_class, group = "study_id", xlab = "lnVR",
data = data, mod = "behaviour_measured_standardised", k.pos = "right", colour = FALSE,
fill = FALSE, trunk.size = 4, branch.size = 2, twig.size = 1)
Moderate by assay (lnRR)
lnRR_mod_assay <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behavioural_assay_standardised2 -
1, method = "REML", test = "t", data = data, sparse = T)
summary(lnRR_mod_assay)##
## Multivariate Meta-Analysis Model (k = 281; method: REML)
##
## logLik Deviance AIC BIC AICc
## -112.3984 224.7968 238.7968 264.1901 239.2116
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0551 0.2347 28 no study_id
## sigma^2.2 0.0597 0.2444 281 no assay_id
## sigma^2.3 0.0300 0.1732 8 no species_latin
## sigma^2.4 0.0170 0.1303 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 278) = 2767.0298, p-val < .0001
##
## Test of Moderators (coefficients 1:3):
## F(df1 = 3, df2 = 278) = 2.4162, p-val = 0.0667
##
## Model Results:
##
## estimate se tval df pval
## behavioural_assay_standardised2count -0.2306 0.1073 -2.1496 278 0.0324
## behavioural_assay_standardised2entry -0.4129 0.1652 -2.4996 278 0.0130
## behavioural_assay_standardised2zone -0.2541 0.1106 -2.2967 278 0.0224
## ci.lb ci.ub
## behavioural_assay_standardised2count -0.4417 -0.0194 *
## behavioural_assay_standardised2entry -0.7381 -0.0877 *
## behavioural_assay_standardised2zone -0.4719 -0.0363 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## R2_marginal R2_conditional
## 0.009435225 0.896025643# contrast
lnRR_mod_assay_contrast <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behavioural_assay_standardised2,
method = "REML", test = "t", data = data, sparse = T)
summary(lnRR_mod_assay_contrast)##
## Multivariate Meta-Analysis Model (k = 281; method: REML)
##
## logLik Deviance AIC BIC AICc
## -112.3984 224.7968 238.7968 264.1901 239.2116
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0551 0.2347 28 no study_id
## sigma^2.2 0.0597 0.2444 281 no assay_id
## sigma^2.3 0.0300 0.1732 8 no species_latin
## sigma^2.4 0.0170 0.1303 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 278) = 2767.0298, p-val < .0001
##
## Test of Moderators (coefficients 2:3):
## F(df1 = 2, df2 = 278) = 0.8597, p-val = 0.4244
##
## Model Results:
##
## estimate se tval df pval
## intrcpt -0.2306 0.1073 -2.1496 278 0.0324
## behavioural_assay_standardised2entry -0.1823 0.1397 -1.3056 278 0.1928
## behavioural_assay_standardised2zone -0.0235 0.0607 -0.3879 278 0.6984
## ci.lb ci.ub
## intrcpt -0.4417 -0.0194 *
## behavioural_assay_standardised2entry -0.4573 0.0926
## behavioural_assay_standardised2zone -0.1430 0.0959
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_assay_contrast, group = "study_id", xlab = "lnVR",
data = data, mod = "behavioural_assay_standardised2", k.pos = "right", colour = FALSE,
fill = FALSE)
# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_assay, group = "study_id", xlab = "lnRR", data = data,
mod = "behavioural_assay_standardised2", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by assay (lnVR)
lnVR_mod_assay <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behavioural_assay_standardised2 -
1, method = "REML", test = "t", data = data, sparse = T)
summary(lnVR_mod_assay)##
## Multivariate Meta-Analysis Model (k = 281; method: REML)
##
## logLik Deviance AIC BIC AICc
## -203.7426 407.4852 421.4852 446.8785 421.9000
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0029 0.0536 28 no study_id
## sigma^2.2 0.1801 0.4244 281 no assay_id
## sigma^2.3 0.0259 0.1610 8 no species_latin
## sigma^2.4 0.0173 0.1316 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 278) = 1922.3628, p-val < .0001
##
## Test of Moderators (coefficients 1:3):
## F(df1 = 3, df2 = 278) = 3.6855, p-val = 0.0125
##
## Model Results:
##
## estimate se tval df pval
## behavioural_assay_standardised2count -0.2039 0.0983 -2.0742 278 0.0390
## behavioural_assay_standardised2entry -0.5645 0.1822 -3.0986 278 0.0021
## behavioural_assay_standardised2zone -0.1516 0.1046 -1.4496 278 0.1483
## ci.lb ci.ub
## behavioural_assay_standardised2count -0.3973 -0.0104 *
## behavioural_assay_standardised2entry -0.9231 -0.2059 **
## behavioural_assay_standardised2zone -0.3574 0.0543
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# contrast
lnVR_mod_assay_contrast <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behavioural_assay_standardised2,
method = "REML", test = "t", data = data, sparse = T)
summary(lnVR_mod_assay_contrast)##
## Multivariate Meta-Analysis Model (k = 281; method: REML)
##
## logLik Deviance AIC BIC AICc
## -203.7426 407.4852 421.4852 446.8785 421.9000
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0029 0.0536 28 no study_id
## sigma^2.2 0.1801 0.4244 281 no assay_id
## sigma^2.3 0.0259 0.1610 8 no species_latin
## sigma^2.4 0.0173 0.1316 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 278) = 1922.3628, p-val < .0001
##
## Test of Moderators (coefficients 2:3):
## F(df1 = 2, df2 = 278) = 3.2048, p-val = 0.0421
##
## Model Results:
##
## estimate se tval df pval
## intrcpt -0.2039 0.0983 -2.0742 278 0.0390
## behavioural_assay_standardised2entry -0.3606 0.1717 -2.0999 278 0.0366
## behavioural_assay_standardised2zone 0.0523 0.0826 0.6328 278 0.5274
## ci.lb ci.ub
## intrcpt -0.3973 -0.0104 *
## behavioural_assay_standardised2entry -0.6987 -0.0226 *
## behavioural_assay_standardised2zone -0.1104 0.2149
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_assay_contrast, group = "study_id", xlab = "lnVR",
data = data, mod = "behavioural_assay_standardised2", k.pos = "right", colour = FALSE,
fill = FALSE)
Pesticide characteristics
Moderate by pesticide chemical class (lnRR)
# Model
lnRR_mod_pesticide <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~pesticide_chemical_class -
1, method = "REML", test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_pesticide)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -154.4215 308.8431 342.8431 412.1239 344.3107
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0740 0.2720 37 no study_id
## sigma^2.2 0.0569 0.2385 448 no assay_id
## sigma^2.3 0.1006 0.3172 10 no species_latin
## sigma^2.4 0.0000 0.0000 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 435) = 4102.5996, p-val < .0001
##
## Test of Moderators (coefficients 1:13):
## F(df1 = 13, df2 = 435) = 1.2519, p-val = 0.2396
##
## Model Results:
##
## estimate se
## pesticide_chemical_classB-methoxyacrylates -0.3506 0.3156
## pesticide_chemical_classcarbamate -0.5231 0.3150
## pesticide_chemical_classdioxolanes -0.4687 0.3237
## pesticide_chemical_classneonicotinoid -0.3278 0.2279
## pesticide_chemical_classorganochlorine -0.4560 0.2020
## pesticide_chemical_classorganophosphate -0.2562 0.1657
## pesticide_chemical_classorganophosphate and organochlorine -0.3905 0.3074
## pesticide_chemical_classphenoxy -0.2870 0.3277
## pesticide_chemical_classpyrethroid -0.3401 0.1850
## pesticide_chemical_classrotenones 0.0826 0.2823
## pesticide_chemical_classtriazine -0.3017 0.1759
## pesticide_chemical_classtriazole -0.5014 0.2123
## pesticide_chemical_classurea 0.0209 0.1939
## tval df
## pesticide_chemical_classB-methoxyacrylates -1.1110 435
## pesticide_chemical_classcarbamate -1.6605 435
## pesticide_chemical_classdioxolanes -1.4481 435
## pesticide_chemical_classneonicotinoid -1.4381 435
## pesticide_chemical_classorganochlorine -2.2570 435
## pesticide_chemical_classorganophosphate -1.5459 435
## pesticide_chemical_classorganophosphate and organochlorine -1.2705 435
## pesticide_chemical_classphenoxy -0.8759 435
## pesticide_chemical_classpyrethroid -1.8387 435
## pesticide_chemical_classrotenones 0.2925 435
## pesticide_chemical_classtriazine -1.7149 435
## pesticide_chemical_classtriazole -2.3614 435
## pesticide_chemical_classurea 0.1078 435
## pval ci.lb
## pesticide_chemical_classB-methoxyacrylates 0.2672 -0.9709
## pesticide_chemical_classcarbamate 0.0975 -1.1422
## pesticide_chemical_classdioxolanes 0.1483 -1.1049
## pesticide_chemical_classneonicotinoid 0.1511 -0.7758
## pesticide_chemical_classorganochlorine 0.0245 -0.8530
## pesticide_chemical_classorganophosphate 0.1229 -0.5819
## pesticide_chemical_classorganophosphate and organochlorine 0.2046 -0.9946
## pesticide_chemical_classphenoxy 0.3816 -0.9310
## pesticide_chemical_classpyrethroid 0.0666 -0.7036
## pesticide_chemical_classrotenones 0.7700 -0.4723
## pesticide_chemical_classtriazine 0.0871 -0.6475
## pesticide_chemical_classtriazole 0.0186 -0.9188
## pesticide_chemical_classurea 0.9142 -0.3601
## ci.ub
## pesticide_chemical_classB-methoxyacrylates 0.2696
## pesticide_chemical_classcarbamate 0.0961 .
## pesticide_chemical_classdioxolanes 0.1675
## pesticide_chemical_classneonicotinoid 0.1202
## pesticide_chemical_classorganochlorine -0.0589 *
## pesticide_chemical_classorganophosphate 0.0695
## pesticide_chemical_classorganophosphate and organochlorine 0.2136
## pesticide_chemical_classphenoxy 0.3570
## pesticide_chemical_classpyrethroid 0.0234 .
## pesticide_chemical_classrotenones 0.6374
## pesticide_chemical_classtriazine 0.0441 .
## pesticide_chemical_classtriazole -0.0841 *
## pesticide_chemical_classurea 0.4019
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_pesticide, mod = "pesticide_chemical_class", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL
## 1 B-methoxyacrylates -0.35063408 -0.9709119 0.26964378
## 2 Carbamate -0.52308206 -1.1422233 0.09605917
## 3 Dioxolanes -0.46873244 -1.1049181 0.16745325
## 4 Neonicotinoid -0.32780850 -0.7758217 0.12020467
## 5 Organochlorine -0.45595648 -0.8530050 -0.05890797
## 6 Organophosphate -0.25616888 -0.5818640 0.06952622
## 7 Organophosphate and organochlorine -0.39051243 -0.9946148 0.21358997
## 8 Phenoxy -0.28697857 -0.9309615 0.35700438
## 9 Pyrethroid -0.34009657 -0.7036252 0.02343208
## 10 Rotenones 0.08257307 -0.4722692 0.63741531
## 11 Triazine -0.30169665 -0.6474717 0.04407839
## 12 Triazole -0.50141974 -0.9187685 -0.08407095
## 13 Urea 0.02089783 -0.3601313 0.40192698
## lowerPR upperPR
## 1 -1.4815457 0.7802775
## 2 -1.6533707 0.6072065
## 3 -1.6084467 0.6709819
## 4 -1.3741986 0.7185816
## 5 -1.4815607 0.5696477
## 6 -1.2563157 0.7439780
## 7 -1.5126337 0.7316088
## 8 -1.4310636 0.8571064
## 9 -1.3531955 0.6730024
## 10 -1.0138148 1.1789609
## 11 -1.3085615 0.7051682
## 12 -1.5350524 0.5322129
## 13 -0.9986117 1.0404073## R2_marginal R2_conditional
## 0.1028894 1.0000000orchaRd::orchard_plot(lnRR_mod_pesticide, group = "study_id", xlab = "lnRR", data = data,
angle = 0, mod = "pesticide_chemical_class", k.pos = "right", colour = FALSE,
fill = FALSE)
Moderate by pesticide chemical class (lnVR)
# Model
lnVR_mod_pesticide <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~pesticide_chemical_class -
1, method = "REML", test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_pesticide)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -374.3551 748.7102 782.7102 851.9911 784.1778
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0001 37 no study_id
## sigma^2.2 0.2512 0.5012 448 no assay_id
## sigma^2.3 0.0187 0.1366 10 no species_latin
## sigma^2.4 0.0000 0.0000 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 435) = 3523.7293, p-val < .0001
##
## Test of Moderators (coefficients 1:13):
## F(df1 = 13, df2 = 435) = 1.6681, p-val = 0.0649
##
## Model Results:
##
## estimate se
## pesticide_chemical_classB-methoxyacrylates -0.0979 0.1613
## pesticide_chemical_classcarbamate -0.0717 0.2871
## pesticide_chemical_classdioxolanes 0.3694 0.2579
## pesticide_chemical_classneonicotinoid 0.0567 0.1425
## pesticide_chemical_classorganochlorine 0.0633 0.1799
## pesticide_chemical_classorganophosphate -0.2923 0.1052
## pesticide_chemical_classorganophosphate and organochlorine -0.0181 0.3221
## pesticide_chemical_classphenoxy 0.0844 0.2109
## pesticide_chemical_classpyrethroid 0.0379 0.1048
## pesticide_chemical_classrotenones 0.1417 0.2121
## pesticide_chemical_classtriazine -0.0180 0.1133
## pesticide_chemical_classtriazole -0.2512 0.1157
## pesticide_chemical_classurea 0.0229 0.1239
## tval df
## pesticide_chemical_classB-methoxyacrylates -0.6066 435
## pesticide_chemical_classcarbamate -0.2496 435
## pesticide_chemical_classdioxolanes 1.4321 435
## pesticide_chemical_classneonicotinoid 0.3977 435
## pesticide_chemical_classorganochlorine 0.3517 435
## pesticide_chemical_classorganophosphate -2.7775 435
## pesticide_chemical_classorganophosphate and organochlorine -0.0563 435
## pesticide_chemical_classphenoxy 0.4000 435
## pesticide_chemical_classpyrethroid 0.3617 435
## pesticide_chemical_classrotenones 0.6680 435
## pesticide_chemical_classtriazine -0.1588 435
## pesticide_chemical_classtriazole -2.1709 435
## pesticide_chemical_classurea 0.1848 435
## pval ci.lb
## pesticide_chemical_classB-methoxyacrylates 0.5445 -0.4150
## pesticide_chemical_classcarbamate 0.8030 -0.6360
## pesticide_chemical_classdioxolanes 0.1528 -0.1376
## pesticide_chemical_classneonicotinoid 0.6910 -0.2233
## pesticide_chemical_classorganochlorine 0.7252 -0.2903
## pesticide_chemical_classorganophosphate 0.0057 -0.4992
## pesticide_chemical_classorganophosphate and organochlorine 0.9551 -0.6512
## pesticide_chemical_classphenoxy 0.6893 -0.3302
## pesticide_chemical_classpyrethroid 0.7178 -0.1680
## pesticide_chemical_classrotenones 0.5045 -0.2751
## pesticide_chemical_classtriazine 0.8739 -0.2407
## pesticide_chemical_classtriazole 0.0305 -0.4785
## pesticide_chemical_classurea 0.8535 -0.2207
## ci.ub
## pesticide_chemical_classB-methoxyacrylates 0.2192
## pesticide_chemical_classcarbamate 0.4927
## pesticide_chemical_classdioxolanes 0.8763
## pesticide_chemical_classneonicotinoid 0.3367
## pesticide_chemical_classorganochlorine 0.4169
## pesticide_chemical_classorganophosphate -0.0855 **
## pesticide_chemical_classorganophosphate and organochlorine 0.6149
## pesticide_chemical_classphenoxy 0.4989
## pesticide_chemical_classpyrethroid 0.2438
## pesticide_chemical_classrotenones 0.5585
## pesticide_chemical_classtriazine 0.2047
## pesticide_chemical_classtriazole -0.0238 *
## pesticide_chemical_classurea 0.2665
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_pesticide, mod = "pesticide_chemical_class", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL
## 1 B-methoxyacrylates -0.09786488 -0.4149748 0.21924507
## 2 Carbamate -0.07166464 -0.6359977 0.49266842
## 3 Dioxolanes 0.36939003 -0.1375599 0.87633994
## 4 Neonicotinoid 0.05665895 -0.2233324 0.33665025
## 5 Organochlorine 0.06327913 -0.2903200 0.41687828
## 6 Organophosphate -0.29232203 -0.4991783 -0.08546579
## 7 Organophosphate and organochlorine -0.01813324 -0.6511866 0.61492014
## 8 Phenoxy 0.08437329 -0.3301778 0.49892440
## 9 Pyrethroid 0.03788844 -0.1680062 0.24378311
## 10 Rotenones 0.14165975 -0.2751454 0.55846496
## 11 Triazine -0.01799302 -0.2406635 0.20467741
## 12 Triazole -0.25115498 -0.4785357 -0.02377427
## 13 Urea 0.02290242 -0.2206589 0.26646373
## lowerPR upperPR
## 1 -1.1669418 0.9712120
## 2 -1.2382145 1.0948852
## 3 -0.7705068 1.5092869
## 4 -1.0020014 1.1153193
## 5 -1.0171833 1.1437415
## 6 -1.3340303 0.7493863
## 7 -1.2194339 1.1831674
## 8 -1.0175429 1.1862895
## 9 -1.0036294 1.0794062
## 10 -0.9611064 1.2444259
## 11 -1.0629566 1.0269705
## 12 -1.2971324 0.7948224
## 13 -1.0267112 1.0725161## R2_marginal R2_conditional
## 0.08581531 1.00000000# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_pesticide, group = "study_id", xlab = "lnVR", data = data,
mod = "pesticide_chemical_class", k.pos = "right", angle = 0, colour = FALSE,
fill = FALSE)
Moderate by concentration of pesticide (lnRR)
# Create dataframe for model with consistent dosage units
data_dosage_model <- data %>%
filter(dosage != "not reported") %>%
filter(dosage_unit != "not reported") %>%
filter(!dosage_unit %in% c("nm", "um", "nM")) %>%
mutate(dosage = as.numeric(dosage), dosage_unit = as.character(dosage_unit),
dosage_unit_consistent = case_when(dosage_unit == "mg/L" ~ "ug/L", dosage_unit ==
"ng/L" ~ "ug/L", dosage_unit == "g/L" ~ "ug/L", dosage_unit == "ppb" ~
"ug/L", dosage_unit == "ppm" ~ "ug/L", TRUE ~ dosage_unit), dosage_convert_ugL = case_when(dosage_unit ==
"mg/L" ~ dosage * 1000, dosage_unit == "ng/L" ~ dosage/1000, dosage_unit ==
"g/L" ~ dosage/1e+06, dosage_unit == "ppm" ~ dosage * 1000, TRUE ~ dosage)) %>%
filter(!is.na(dosage_convert_ugL)) %>%
mutate(log_dosage_convert_ugL = log(dosage_convert_ugL))
# Recalculate the VCV matrix based on the new data frame
lnRRVCV_dosage <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id, data = data_dosage_model,
rho = 0.5)
# Model
lnRR_mod_dosage <- rma.mv(yi = lnRR, V = lnRRVCV_dosage, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~log_dosage_convert_ugL -
1, method = "REML", test = "t", data = data_dosage_model, sparse = T)
# Summary results
summary(lnRR_mod_dosage)##
## Multivariate Meta-Analysis Model (k = 424; method: REML)
##
## logLik Deviance AIC BIC AICc
## -160.0658 320.1317 330.1317 350.3685 330.2756
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0642 0.2535 33 no study_id
## sigma^2.2 0.0593 0.2435 424 no assay_id
## sigma^2.3 0.0937 0.3062 10 no species_latin
## sigma^2.4 0.0068 0.0823 26 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 423) = 4780.6970, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## log_dosage_convert_ugL -0.0090 0.0083 -1.0780 423 0.2817 -0.0254 0.0074
##
## log_dosage_convert_ugL
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1dosage_mod_lnRR_results <- mod_results(lnRR_mod_dosage, mod = "log_dosage_convert_ugL",
data = data_dosage_model, group = "study_id") # For prediction intervals
r2_lnRR_dosage <- r2_ml(lnRR_mod_dosage, data_dosage_model)
# Bubble plot
bubble_plot(dosage_mod_lnRR_results, mod = "log_dosage_convert_ugL", group = "study_id",
data = data_dosage_model, x = "dosage_convert_ugL", y = "lnRR", est.lwd = 1,
legend.pos = "bottom.right", k.pos = "bottom.left", ci.col = "red", pi.col = "black",
est.col = "black", g = TRUE) + annotate(geom = "text", x = 7, y = 6.2, label = paste0("italic(R)^{2} == ",
round(r2_lnRR_dosage[1], 4)), color = "black", parse = TRUE, size = 4) + ggtitle("") +
theme(plot.title = element_text(size = 18), legend.position = "none", axis.title.x = element_text(size = 16),
axis.title.y = element_text(size = 16), axis.text.y = element_text(size = 14),
axis.text.x = element_text(size = 14)) + xlab("Dosage")
Moderate by concentration of pesticide (lnVR)
# Recalculate the VCV matrix based on the new data frame
lnVRVCV_dosage <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id, data = data_dosage_model,
rho = 0.5)
## Model
lnVR_mod_dosage <- rma.mv(yi = lnVR, V = lnVRVCV_dosage, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~log_dosage_convert_ugL -
1, method = "REML", test = "t", data = data_dosage_model, sparse = T)
# Summary results
summary(lnVR_mod_dosage)##
## Multivariate Meta-Analysis Model (k = 424; method: REML)
##
## logLik Deviance AIC BIC AICc
## -377.7153 755.4307 765.4307 785.6675 765.5745
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0146 0.1207 33 no study_id
## sigma^2.2 0.2650 0.5148 424 no assay_id
## sigma^2.3 0.0000 0.0000 10 no species_latin
## sigma^2.4 0.0000 0.0000 26 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 423) = 3576.1874, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## log_dosage_convert_ugL -0.0140 0.0093 -1.5142 423 0.1307 -0.0323 0.0042
##
## log_dosage_convert_ugL
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1dosage_mod_lnVR_results <- mod_results(lnVR_mod_dosage, mod = "log_dosage_convert_ugL",
data = data_dosage_model, group = "study_id") # For prediction intervals
r2_lnVR_dosage <- r2_ml(lnVR_mod_dosage, data_dosage_model)
# Bubble plot
bubble_plot(dosage_mod_lnVR_results, mod = "log_dosage_convert_ugL", group = "study_id",
data = data_dosage_model, x = "dosage_convert_ugL", y = "lnVR", est.lwd = 1,
legend.pos = "bottom.right", k.pos = "bottom.left", ci.col = "red", pi.col = "black",
est.col = "black", g = TRUE) + annotate(geom = "text", x = 7, y = 6.2, label = paste0("italic(R)^{2} == ",
round(r2_lnVR_dosage[1], 4)), color = "black", parse = TRUE, size = 4) + ggtitle("") +
theme(plot.title = element_text(size = 18), legend.position = "none", axis.title.x = element_text(size = 16),
axis.title.y = element_text(size = 16), axis.text.y = element_text(size = 14),
axis.text.x = element_text(size = 14)) + xlab("Dosage")
Moderate by duration of pesticide (lnRR)
# Create dataframe for model with consistent duration units
data_duration_model <- data %>%
filter(!is.na(duration), duration != "not reported") %>%
mutate(duration = as.numeric(duration), duration_unit = as.character(duration_unit),
duration_unit_consistent = case_when(duration_unit == "minutes" ~ "hours",
duration_unit == "days" ~ "hours", duration_unit == "weeks" ~ "hours",
TRUE ~ duration_unit), duration_convert = case_when(duration_unit ==
"minutes" ~ duration/60, duration_unit == "days" ~ duration * 24, duration_unit ==
"weeks" ~ duration * 168, TRUE ~ duration))
# Recalculate the VCV matrix based on the new data frame
lnRRVCV_duration <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id,
data = data_duration_model, rho = 0.5)
# Model
lnRR_mod_duration <- rma.mv(yi = lnRR, V = lnRRVCV_duration, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~duration_convert -
1, method = "REML", test = "t", data = data_duration_model, sparse = T)
# Summary results
summary(lnRR_mod_duration)##
## Multivariate Meta-Analysis Model (k = 447; method: REML)
##
## logLik Deviance AIC BIC AICc
## -171.6113 343.2226 353.2226 373.7242 353.3590
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0630 0.2510 36 no study_id
## sigma^2.2 0.0581 0.2411 447 no assay_id
## sigma^2.3 0.0943 0.3070 10 no species_latin
## sigma^2.4 0.0064 0.0797 29 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 446) = 5152.2750, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## duration_convert -0.0001 0.0001 -0.8544 446 0.3933 -0.0002 0.0001
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1duration_mod_lnRR_results <- mod_results(lnRR_mod_duration, mod = "duration_convert",
data = data_duration_model, group = "study_id") # For prediction intervals
r2_lnRR_duration <- r2_ml(lnRR_mod_duration, data_duration_model)
# Bubble plot
bubble_plot(duration_mod_lnRR_results, mod = "duration_convert", group = "study_id",
data = data_duration_model, x = "duration_convert", y = "lnRR", est.lwd = 1,
legend.pos = "bottom.right", k.pos = "bottom.left", ci.col = "red", pi.col = "black",
est.col = "black", g = TRUE) + annotate(geom = "text", x = 7, y = 6.2, label = paste0("italic(R)^{2} == ",
round(r2_lnRR_duration[1], 4)), color = "black", parse = TRUE, size = 4) + ggtitle("") +
theme(plot.title = element_text(size = 18), legend.position = "none", axis.title.x = element_text(size = 16),
axis.title.y = element_text(size = 16), axis.text.y = element_text(size = 14),
axis.text.x = element_text(size = 14)) + xlab("Duration")
Moderate by duration of pesticide (lnVR)
# Recalculate the VCV matrix based on the new data frame
lnVRVCV_duration <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id,
data = data_duration_model, rho = 0.5)
## Model
lnVR_mod_duration <- rma.mv(yi = lnVR, V = lnVRVCV_duration, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~log(duration_convert) -
1, method = "REML", test = "t", data = data_duration_model, sparse = T)
# Summary results
summary(lnVR_mod_duration)##
## Multivariate Meta-Analysis Model (k = 447; method: REML)
##
## logLik Deviance AIC BIC AICc
## -390.3365 780.6730 790.6730 811.1746 790.8093
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0105 0.1024 36 no study_id
## sigma^2.2 0.2509 0.5009 447 no assay_id
## sigma^2.3 0.0241 0.1553 10 no species_latin
## sigma^2.4 0.0024 0.0485 29 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 446) = 3618.9593, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## log(duration_convert) -0.0112 0.0129 -0.8625 446 0.3889 -0.0366 0.0143
##
## log(duration_convert)
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1lnVR_mod_duration_results <- mod_results(lnVR_mod_duration, mod = "duration_convert",
data = data_duration_model, group = "study_id") # For prediction intervals
r2_lnVR_duration <- r2_ml(lnVR_mod_duration, data_duration_model)
# Bubble plot
bubble_plot(lnVR_mod_duration_results, mod = "duration_convert", group = "study_id",
data = data_duration_model, x = "duration_convert", y = "lnVR", est.lwd = 1,
legend.pos = "bottom.right", k.pos = "bottom.left", ci.col = "red", pi.col = "black",
est.col = "black", g = TRUE) + annotate(geom = "text", x = 7, y = 6.2, label = paste0("italic(R)^{2} == ",
round(r2_lnVR_duration[1], 4)), color = "black", parse = TRUE, size = 4) + ggtitle("") +
theme(plot.title = element_text(size = 18), legend.position = "none", axis.title.x = element_text(size = 16),
axis.title.y = element_text(size = 16), axis.text.y = element_text(size = 14),
axis.text.x = element_text(size = 14)) + xlab("Duration")
Moderate by control solvent used (lnRR)
# Model
lnRR_mod_solvent <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~control_solvent - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_solvent)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -158.2294 316.4588 336.4588 377.3719 336.9692
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0525 0.2292 37 no study_id
## sigma^2.2 0.0560 0.2366 448 no assay_id
## sigma^2.3 0.0901 0.3002 10 no species_latin
## sigma^2.4 0.0100 0.1001 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 442) = 4609.1221, p-val < .0001
##
## Test of Moderators (coefficients 1:6):
## F(df1 = 6, df2 = 442) = 3.2090, p-val = 0.0043
##
## Model Results:
##
## estimate se tval df pval ci.lb
## control_solventacetone -0.4324 0.2101 -2.0582 442 0.0402 -0.8453
## control_solventDMSO -0.2572 0.1430 -1.7994 442 0.0726 -0.5382
## control_solventDTNB 0.3652 0.3579 1.0203 442 0.3081 -0.3382
## control_solventethanol -0.0796 0.3061 -0.2602 442 0.7949 -0.6813
## control_solventnone -0.4687 0.1473 -3.1828 442 0.0016 -0.7581
## control_solventnot reported -0.3131 0.1452 -2.1562 442 0.0316 -0.5986
## ci.ub
## control_solventacetone -0.0195 *
## control_solventDMSO 0.0237 .
## control_solventDTNB 1.0686
## control_solventethanol 0.5220
## control_solventnone -0.1793 **
## control_solventnot reported -0.0277 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_solvent, mod = "control_solvent", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Acetone -0.43239818 -0.8452817 -0.01951462 -1.4205239 0.5557275
## 2 DMSO -0.25723535 -0.5381937 0.02372303 -1.1979038 0.6834331
## 3 DTNB 0.36517835 -0.3382454 1.06860210 -0.7753148 1.5056715
## 4 Ethanol -0.07964196 -0.6813076 0.52202365 -1.1603459 1.0010620
## 5 None -0.46870558 -0.7581296 -0.17928159 -1.4119372 0.4745260
## 6 Not reported -0.31314903 -0.5985793 -0.02771877 -1.2551628 0.6288648## R2_marginal R2_conditional
## 0.09182819 0.95638011# Model
lnRR_mod_solvent2 <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~solvent2 - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_solvent2)##
## Multivariate Meta-Analysis Model (k = 322; method: REML)
##
## logLik Deviance AIC BIC AICc
## -104.4008 208.8016 220.8016 243.4115 221.0700
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0233 0.1526 26 no study_id
## sigma^2.2 0.0561 0.2368 322 no assay_id
## sigma^2.3 0.0343 0.1851 7 no species_latin
## sigma^2.4 0.0366 0.1913 23 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 320) = 3517.4706, p-val < .0001
##
## Test of Moderators (coefficients 1:2):
## F(df1 = 2, df2 = 320) = 7.4927, p-val = 0.0007
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## solvent2none -0.4323 0.1243 -3.4767 320 0.0006 -0.6769 -0.1877
## solvent2solvent_used -0.2364 0.1140 -2.0741 320 0.0389 -0.4607 -0.0122
##
## solvent2none ***
## solvent2solvent_used *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_solvent2, mod = "solvent2", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 None -0.4322903 -0.6769184 -0.18766232 -1.233181 0.3686002
## 2 Solvent_used -0.2364478 -0.4607294 -0.01216618 -1.031360 0.5584642## R2_marginal R2_conditional
## 0.05832539 0.77057361# Contrast Model
lnRR_mod_solvent2_contrast <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~solvent2, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_solvent2_contrast)##
## Multivariate Meta-Analysis Model (k = 322; method: REML)
##
## logLik Deviance AIC BIC AICc
## -104.4008 208.8016 220.8016 243.4115 221.0700
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0233 0.1526 26 no study_id
## sigma^2.2 0.0561 0.2368 322 no assay_id
## sigma^2.3 0.0343 0.1851 7 no species_latin
## sigma^2.4 0.0366 0.1913 23 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 320) = 3517.4706, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 320) = 8.9451, p-val = 0.0030
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.4323 0.1243 -3.4767 320 0.0006 -0.6769 -0.1877
## solvent2solvent_used 0.1958 0.0655 2.9908 320 0.0030 0.0670 0.3247
##
## intrcpt ***
## solvent2solvent_used **
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_solvent2_contrast, mod = "solvent2", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 None -0.4322903 -0.6769184 -0.18766232 -1.233181 0.3686002
## 2 Solvent_used -0.2364478 -0.4607294 -0.01216618 -1.031360 0.5584642## R2_marginal R2_conditional
## 0.05832539 0.77057361# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_solvent, group = "study_id", xlab = "lnRR", data = data,
mod = "control_solvent", k.pos = "right", colour = FALSE, fill = FALSE)
# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_solvent2, group = "study_id", xlab = "lnRR", data = data,
mod = "solvent2", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by control solvent used (lnVR)
# Model
lnVR_mod_solvent <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~control_solvent - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_solvent)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -383.0086 766.0171 786.0171 826.9302 786.5276
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0056 0.0750 37 no study_id
## sigma^2.2 0.2463 0.4963 448 no assay_id
## sigma^2.3 0.0664 0.2578 10 no species_latin
## sigma^2.4 0.0088 0.0937 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 442) = 3591.5475, p-val < .0001
##
## Test of Moderators (coefficients 1:6):
## F(df1 = 6, df2 = 442) = 1.1873, p-val = 0.3118
##
## Model Results:
##
## estimate se tval df pval ci.lb
## control_solventacetone 0.0357 0.2062 0.1732 442 0.8626 -0.3695
## control_solventDMSO -0.1065 0.1259 -0.8456 442 0.3982 -0.3540
## control_solventDTNB -0.1484 0.4262 -0.3483 442 0.7278 -0.9860
## control_solventethanol 0.6455 0.3544 1.8210 442 0.0693 -0.0512
## control_solventnone -0.1624 0.1355 -1.1984 442 0.2314 -0.4286
## control_solventnot reported -0.1506 0.1282 -1.1752 442 0.2406 -0.4025
## ci.ub
## control_solventacetone 0.4409
## control_solventDMSO 0.1410
## control_solventDTNB 0.6892
## control_solventethanol 1.3421 .
## control_solventnone 0.1039
## control_solventnot reported 0.1013
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_solvent, mod = "control_solvent", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Acetone 0.03570967 -0.36945573 0.4408751 -1.1592330 1.230652
## 2 DMSO -0.10649681 -0.35401172 0.1410181 -1.2575801 1.044586
## 3 DTNB -0.14843971 -0.98603407 0.6891546 -1.5503289 1.253449
## 4 Ethanol 0.64545014 -0.05116164 1.3420619 -0.6770464 1.967947
## 5 None -0.16236262 -0.42863825 0.1039130 -1.3176252 0.992900
## 6 Not reported -0.15061013 -0.40248779 0.1012675 -1.3026394 1.001419## R2_marginal R2_conditional
## 0.06827873 0.97500236# Model
lnVR_mod_solvent2 <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~solvent2 - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_solvent2)##
## Multivariate Meta-Analysis Model (k = 322; method: REML)
##
## logLik Deviance AIC BIC AICc
## -300.4493 600.8985 612.8985 635.5085 613.1669
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 26 no study_id
## sigma^2.2 0.2755 0.5249 322 no assay_id
## sigma^2.3 0.3615 0.6013 7 no species_latin
## sigma^2.4 0.0210 0.1450 23 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 320) = 2479.8766, p-val < .0001
##
## Test of Moderators (coefficients 1:2):
## F(df1 = 2, df2 = 320) = 0.4568, p-val = 0.6337
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## solvent2none -0.0140 0.2687 -0.0523 320 0.9584 -0.5427 0.5146
## solvent2solvent_used 0.0752 0.2552 0.2949 320 0.7683 -0.4268 0.5772
##
## solvent2none
## solvent2solvent_used
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_solvent2, mod = "solvent2", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 None -0.01404355 -0.5427048 0.5146177 -1.695284 1.667197
## 2 Solvent_used 0.07524158 -0.4267601 0.5772433 -1.597807 1.748290## R2_marginal R2_conditional
## 0.002930854 0.968125747# Model
lnVR_mod_solvent2_contrast <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~solvent2, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_solvent2_contrast)##
## Multivariate Meta-Analysis Model (k = 322; method: REML)
##
## logLik Deviance AIC BIC AICc
## -300.4493 600.8985 612.8985 635.5085 613.1669
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 26 no study_id
## sigma^2.2 0.2755 0.5249 322 no assay_id
## sigma^2.3 0.3615 0.6013 7 no species_latin
## sigma^2.4 0.0210 0.1450 23 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 320) = 2479.8766, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 320) = 0.8497, p-val = 0.3573
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.0140 0.2687 -0.0523 320 0.9584 -0.5427 0.5146
## solvent2solvent_used 0.0893 0.0969 0.9218 320 0.3573 -0.1013 0.2798
##
## intrcpt
## solvent2solvent_used
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_solvent2_contrast, mod = "solvent2", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 None -0.01404355 -0.5427048 0.5146177 -1.695284 1.667197
## 2 Solvent_used 0.07524158 -0.4267601 0.5772433 -1.597807 1.748290## R2_marginal R2_conditional
## 0.002930854 0.968125747# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_solvent, group = "study_id", xlab = "lnVR", data = data,
mod = "control_solvent", k.pos = "right", colour = FALSE, fill = FALSE)
# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_solvent2, group = "study_id", xlab = "lnVR", data = data,
mod = "solvent2", k.pos = "right", colour = FALSE, fill = FALSE)
Species characteristics
Moderate by species (lnRR)
# Model
lnRR_mod_species <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~species_english - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_species)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -155.4986 310.9973 338.9973 396.1484 339.9902
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0599 0.2448 37 no study_id
## sigma^2.2 0.0577 0.2402 448 no assay_id
## sigma^2.3 0.0414 0.2034 10 no species_latin
## sigma^2.4 0.0091 0.0954 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 438) = 4113.4236, p-val < .0001
##
## Test of Moderators (coefficients 1:10):
## F(df1 = 10, df2 = 438) = 1.7271, p-val = 0.0723
##
## Model Results:
##
## estimate se tval df pval ci.lb
## species_englishBleak -1.0922 0.4247 -2.5720 438 0.0104 -1.9268
## species_englishbrown trout 0.0678 0.3881 0.1748 438 0.8614 -0.6949
## species_englishguppy -0.4675 0.3002 -1.5572 438 0.1202 -1.0576
## species_englishIberian barbel 0.1383 0.4125 0.3352 438 0.7376 -0.6724
## species_englishJapanese medaka -0.3932 0.2678 -1.4685 438 0.1427 -0.9194
## species_englishkillifish -0.2456 0.2923 -0.8403 438 0.4012 -0.8200
## species_englishmarine medaka -0.1522 0.3378 -0.4506 438 0.6525 -0.8162
## species_englishNile tilapia -0.6422 0.3964 -1.6201 438 0.1059 -1.4214
## species_englishsailfin mollie -0.2627 0.3345 -0.7852 438 0.4328 -0.9201
## species_englishzebrafish -0.0314 0.2124 -0.1478 438 0.8826 -0.4489
## ci.ub
## species_englishBleak -0.2576 *
## species_englishbrown trout 0.8306
## species_englishguppy 0.1226
## species_englishIberian barbel 0.9490
## species_englishJapanese medaka 0.1330
## species_englishkillifish 0.3288
## species_englishmarine medaka 0.5117
## species_englishNile tilapia 0.1369
## species_englishsailfin mollie 0.3948
## species_englishzebrafish 0.3861
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## R2_marginal R2_conditional
## 0.1119298 0.9518961mod_results(lnRR_mod_species, mod = "species_english", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Bleak -1.09222473 -1.9268424 -0.2576071 -2.2523641 0.06791464
## 2 Brown trout 0.06781772 -0.6949190 0.8305544 -1.0417335 1.17736896
## 3 Guppy -0.46750672 -1.0575814 0.1225679 -1.4662683 0.53125491
## 4 Iberian barbel 0.13827322 -0.6724464 0.9489928 -1.0047942 1.28134059
## 5 Japanese medaka -0.39320355 -0.9194454 0.1330382 -1.3556313 0.56922418
## 6 Killifish -0.24559470 -0.8200227 0.3288333 -1.2351927 0.74400330
## 7 Marine medaka -0.15223567 -0.8161857 0.5117144 -1.1963460 0.89187465
## 8 Nile tilapia -0.64224990 -1.4213830 0.1368832 -1.7631357 0.47863593
## 9 Sailfin mollie -0.26266801 -0.9201238 0.3947878 -1.3026607 0.77732471
## 10 Zebrafish -0.03139175 -0.4489045 0.3861210 -0.9389454 0.87616190# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_species, group = "study_id", xlab = "lnRR", data = data,
mod = "species_english", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by species (lnVR)
## ModeL
lnVR_mod_species <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~species_english - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_species)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -377.8838 755.7676 783.7676 840.9187 784.7605
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0016 0.0398 37 no study_id
## sigma^2.2 0.2483 0.4983 448 no assay_id
## sigma^2.3 0.0493 0.2220 10 no species_latin
## sigma^2.4 0.0133 0.1155 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 438) = 3559.4309, p-val < .0001
##
## Test of Moderators (coefficients 1:10):
## F(df1 = 10, df2 = 438) = 0.9211, p-val = 0.5134
##
## Model Results:
##
## estimate se tval df pval ci.lb
## species_englishBleak 0.2207 0.4836 0.4564 438 0.6483 -0.7297
## species_englishbrown trout 0.2881 0.3927 0.7337 438 0.4635 -0.4836
## species_englishguppy 0.1616 0.3262 0.4955 438 0.6205 -0.4795
## species_englishIberian barbel 0.0239 0.4836 0.0493 438 0.9607 -0.9265
## species_englishJapanese medaka -0.4085 0.2860 -1.4285 438 0.1539 -0.9705
## species_englishkillifish -0.2176 0.2721 -0.7998 438 0.4243 -0.7523
## species_englishmarine medaka -0.2494 0.2861 -0.8716 438 0.3839 -0.8117
## species_englishNile tilapia -0.8106 0.4098 -1.9782 438 0.0485 -1.6159
## species_englishsailfin mollie 0.2603 0.2757 0.9443 438 0.3455 -0.2815
## species_englishzebrafish -0.0431 0.2276 -0.1893 438 0.8499 -0.4905
## ci.ub
## species_englishBleak 1.1711
## species_englishbrown trout 1.0598
## species_englishguppy 0.8028
## species_englishIberian barbel 0.9742
## species_englishJapanese medaka 0.1535
## species_englishkillifish 0.3171
## species_englishmarine medaka 0.3130
## species_englishNile tilapia -0.0053 *
## species_englishsailfin mollie 0.8022
## species_englishzebrafish 0.4043
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_species, mod = "species_english", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Bleak 0.22071513 -0.7296715 1.171101707 -1.2320258 1.6734560
## 2 Brown trout 0.28808768 -0.4836350 1.059810339 -1.0545878 1.6307631
## 3 Guppy 0.16164958 -0.4795317 0.802830823 -1.1104884 1.4337875
## 4 Iberian barbel 0.02385636 -0.9265302 0.974242935 -1.4288846 1.4765973
## 5 Japanese medaka -0.40847265 -0.9704814 0.153536054 -1.6426020 0.8256567
## 6 Killifish -0.21760996 -0.7523453 0.317125377 -1.4395606 1.0043407
## 7 Marine medaka -0.24937580 -0.8117108 0.312959157 -1.4836538 0.9849022
## 8 Nile tilapia -0.81058807 -1.6159170 -0.005259172 -2.1728568 0.5516807
## 9 Sailfin mollie 0.26034693 -0.2814940 0.802187911 -0.9647299 1.4854237
## 10 Zebrafish -0.04309235 -0.4904626 0.404277928 -1.2294151 1.1432304## R2_marginal R2_conditional
## 0.07062817 0.96033072# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_species, group = "study_id", xlab = "lnVR", data = data,
mod = "species_english", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by sex (lnRR)
# Model
lnRR_mod_sex <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~sex - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_sex)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -166.8356 333.6713 349.6713 382.4379 350.0023
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0599 0.2447 37 no study_id
## sigma^2.2 0.0575 0.2397 448 no assay_id
## sigma^2.3 0.0816 0.2857 10 no species_latin
## sigma^2.4 0.0078 0.0885 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 444) = 4958.0180, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 444) = 1.7540, p-val = 0.1371
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## sexfemale -0.2844 0.1397 -2.0361 444 0.0423 -0.5590 -0.0099 *
## sexmale -0.2671 0.1318 -2.0270 444 0.0433 -0.5260 -0.0081 *
## sexmixed -0.3562 0.1368 -2.6041 444 0.0095 -0.6250 -0.0874 **
## sexnot reported -0.1736 0.1647 -1.0544 444 0.2923 -0.4973 0.1500
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## name estimate lowerCL upperCL lowerPR upperPR
## 1 Female -0.2844447 -0.5590006 -0.009888818 -1.219430 0.6505404
## 2 Male -0.2670605 -0.5260000 -0.008121092 -1.197580 0.6634586
## 3 Mixed -0.3561937 -0.6250184 -0.087369012 -1.289512 0.5771245
## 4 Not reported -0.1736282 -0.4972699 0.150013425 -1.124186 0.7769296## R2_marginal R2_conditional
## 0.0203154 0.9628741data_sex <- data %>%
filter(sex == c("male", "female"))
lnRRVCV_sex <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id, data = data_sex,
rho = 0.5)
lnRR_mod_sex_contrast <- rma.mv(yi = lnRR, V = lnRRVCV_sex, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~sex, method = "REML",
test = "t", data = data_sex, sparse = T)
summary(lnRR_mod_sex_contrast)##
## Multivariate Meta-Analysis Model (k = 72; method: REML)
##
## logLik Deviance AIC BIC AICc
## -16.7421 33.4841 45.4841 58.9751 46.8175
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 13 no study_id
## sigma^2.2 0.0438 0.2094 72 no assay_id
## sigma^2.3 0.0227 0.1506 7 no species_latin
## sigma^2.4 0.0292 0.1709 14 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 70) = 882.3697, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 70) = 0.9921, p-val = 0.3227
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.2357 0.1195 -1.9725 70 0.0525 -0.4740 0.0026 .
## sexmale -0.0809 0.0812 -0.9960 70 0.3227 -0.2429 0.0811
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_sex, group = "study_id", xlab = "lnRR", data = data,
mod = "sex", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by sex (lnVR)
# Model
lnVR_mod_sex <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~sex - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_sex)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -387.6801 775.3602 791.3602 824.1268 791.6913
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0105 0.1022 37 no study_id
## sigma^2.2 0.2502 0.5002 448 no assay_id
## sigma^2.3 0.0299 0.1730 10 no species_latin
## sigma^2.4 0.0040 0.0634 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 444) = 3613.1164, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 444) = 0.5853, p-val = 0.6734
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## sexfemale -0.0686 0.1288 -0.5331 444 0.5943 -0.3217 0.1844
## sexmale -0.0961 0.1046 -0.9186 444 0.3588 -0.3016 0.1095
## sexmixed -0.1303 0.1045 -1.2462 444 0.2133 -0.3357 0.0752
## sexnot reported 0.0381 0.1508 0.2526 444 0.8007 -0.2582 0.3344
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1## name estimate lowerCL upperCL lowerPR upperPR
## 1 Female -0.06863887 -0.3216977 0.18441998 -1.164870 1.0275918
## 2 Male -0.09607752 -0.3016354 0.10948039 -1.182327 0.9901715
## 3 Mixed -0.13027676 -0.3357290 0.07517548 -1.216506 0.9559523
## 4 Not reported 0.03807715 -0.2582014 0.33435569 -1.068930 1.1450838## R2_marginal R2_conditional
## 0.01129353 0.98651090lnVRVCV_sex <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id, data = data_sex,
rho = 0.5)
# Model
lnVR_mod_sex_contrast <- rma.mv(yi = lnVR, V = lnVRVCV_sex, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~sex, method = "REML",
test = "t", data = data_sex, sparse = T)
summary(lnVR_mod_sex_contrast)##
## Multivariate Meta-Analysis Model (k = 72; method: REML)
##
## logLik Deviance AIC BIC AICc
## -73.3252 146.6503 158.6503 172.1413 159.9837
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 13 no study_id
## sigma^2.2 0.3612 0.6010 72 no assay_id
## sigma^2.3 0.0000 0.0000 7 no species_latin
## sigma^2.4 0.0030 0.0550 14 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 70) = 514.7340, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 70) = 0.5050, p-val = 0.4797
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.1526 0.1395 -1.0946 70 0.2775 -0.4308 0.1255
## sexmale 0.1204 0.1694 0.7107 70 0.4797 -0.2174 0.4582
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_sex, group = "study_id", xlab = "lnVR", data = data,
mod = "sex", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by source of fish (lnRR)
## ModeL
lnRR_mod_source <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~source - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnRR_mod_source)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -162.4387 324.8775 344.8775 385.7906 345.3879
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0542 0.2327 37 no study_id
## sigma^2.2 0.0579 0.2406 448 no assay_id
## sigma^2.3 0.0836 0.2892 10 no species_latin
## sigma^2.4 0.0089 0.0945 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 442) = 4015.5954, p-val < .0001
##
## Test of Moderators (coefficients 1:6):
## F(df1 = 6, df2 = 442) = 1.6894, p-val = 0.1218
##
## Model Results:
##
## estimate se tval
## sourcecommercial supplier -0.1124 0.1747 -0.6430
## sourcelaboratory stock from not specified source -0.1486 0.1548 -0.9600
## sourcelabratory stock from commercial supplier -0.0772 0.3051 -0.2529
## sourcelabratory stock from wild population -0.0717 0.1904 -0.3764
## sourcenot reported -0.3323 0.1729 -1.9221
## sourcewild collected -0.5485 0.2000 -2.7429
## df pval ci.lb ci.ub
## sourcecommercial supplier 442 0.5205 -0.4558 0.2311
## sourcelaboratory stock from not specified source 442 0.3376 -0.4528 0.1556
## sourcelabratory stock from commercial supplier 442 0.8005 -0.6768 0.5225
## sourcelabratory stock from wild population 442 0.7068 -0.4459 0.3025
## sourcenot reported 442 0.0552 -0.6721 0.0075
## sourcewild collected 442 0.0063 -0.9416 -0.1555
##
## sourcecommercial supplier
## sourcelaboratory stock from not specified source
## sourcelabratory stock from commercial supplier
## sourcelabratory stock from wild population
## sourcenot reported .
## sourcewild collected **
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_source, mod = "source", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL
## 1 Commercial supplier -0.11236635 -0.4558037
## 2 Laboratory stock from not specified source -0.14860217 -0.4528214
## 3 Labratory stock from commercial supplier -0.07715564 -0.6768393
## 4 Labratory stock from wild population -0.07167204 -0.4458538
## 5 Not reported -0.33232415 -0.6721170
## 6 Wild collected -0.54854971 -0.9415933
## upperCL lowerPR upperPR
## 1 0.231070991 -1.065382 0.8406489
## 2 0.155617080 -1.088197 0.7909925
## 3 0.522527973 -1.149494 0.9951826
## 4 0.302509711 -1.036193 0.8928490
## 5 0.007468741 -1.284032 0.6193838
## 6 -0.155506140 -1.520544 0.4234441## R2_marginal R2_conditional
## 0.05111649 0.95855927## ModeL
lnRR_mod_source_contrast <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~source2, method = "REML",
test = "t", data = data, sparse = T)
summary(lnRR_mod_source_contrast)##
## Multivariate Meta-Analysis Model (k = 398; method: REML)
##
## logLik Deviance AIC BIC AICc
## -155.2056 310.4112 322.4112 346.2997 322.6272
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0501 0.2237 31 no study_id
## sigma^2.2 0.0614 0.2478 398 no assay_id
## sigma^2.3 0.0621 0.2492 10 no species_latin
## sigma^2.4 0.0103 0.1017 22 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 396) = 4165.7334, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 396) = 0.7763, p-val = 0.3788
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.2125 0.1319 -1.6116 396 0.1079 -0.4718 0.0467
## source2wild -0.1583 0.1797 -0.8811 396 0.3788 -0.5117 0.1950
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_source, group = "study_id", xlab = "lnRR", data = data,
mod = "source", k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by source of fish (lnVR)
## Model
lnVR_mod_source <- rma.mv(yi = lnVR, V = lnVRVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~source - 1, method = "REML",
test = "t", data = data, sparse = T)
# Summary results
summary(lnVR_mod_source)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -383.7800 767.5601 787.5601 828.4732 788.0705
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0017 0.0417 37 no study_id
## sigma^2.2 0.2485 0.4985 448 no assay_id
## sigma^2.3 0.0055 0.0742 10 no species_latin
## sigma^2.4 0.0178 0.1334 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 442) = 3580.3382, p-val < .0001
##
## Test of Moderators (coefficients 1:6):
## F(df1 = 6, df2 = 442) = 1.5336, p-val = 0.1654
##
## Model Results:
##
## estimate se tval
## sourcecommercial supplier -0.1429 0.0956 -1.4955
## sourcelaboratory stock from not specified source -0.1487 0.0946 -1.5727
## sourcelabratory stock from commercial supplier 0.1769 0.2894 0.6112
## sourcelabratory stock from wild population 0.1877 0.1245 1.5075
## sourcenot reported -0.1048 0.1130 -0.9278
## sourcewild collected -0.1306 0.1788 -0.7304
## df pval ci.lb ci.ub
## sourcecommercial supplier 442 0.1355 -0.3307 0.0449
## sourcelaboratory stock from not specified source 442 0.1165 -0.3346 0.0371
## sourcelabratory stock from commercial supplier 442 0.5414 -0.3919 0.7458
## sourcelabratory stock from wild population 442 0.1324 -0.0570 0.4323
## sourcenot reported 442 0.3540 -0.3268 0.1172
## sourcewild collected 442 0.4656 -0.4820 0.2208
##
## sourcecommercial supplier
## sourcelaboratory stock from not specified source
## sourcelabratory stock from commercial supplier
## sourcelabratory stock from wild population
## sourcenot reported
## sourcewild collected
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_source, mod = "source", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL
## 1 Commercial supplier -0.1429156 -0.33072809 0.04489699
## 2 Laboratory stock from not specified source -0.1487342 -0.33460711 0.03713867
## 3 Labratory stock from commercial supplier 0.1769108 -0.39193868 0.74576038
## 4 Labratory stock from wild population 0.1876691 -0.05699927 0.43233749
## 5 Not reported -0.1048088 -0.32683132 0.11721381
## 6 Wild collected -0.1305961 -0.48201504 0.22082292
## lowerPR upperPR
## 1 -1.1878016 0.9019705
## 2 -1.1932734 0.8958049
## 3 -0.9978671 1.3516888
## 4 -0.8689178 1.2442560
## 5 -1.1563825 0.9467650
## 6 -1.2168781 0.9556860## R2_marginal R2_conditional
## 0.04001628 0.93756601# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_source, group = "study_id", xlab = "lnVR", data = data,
mod = "source", k.pos = "right", colour = FALSE, fill = FALSE)
Model selection and multi-model inference
lnRR model selection and multi-model inference
mlmr.full.lnRR <- rma.mv(yi = lnRR,
V = lnRRVCV,
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
mods = ~ behaviour_measured_standardised + behavioural_assay_standardised2 + pesticide_chemical_class + control_solvent +
species_latin + sex + source,
method = "ML",
test = "t",
data = data,
sparse = T)
r2_ml(mlmr.full.lnRR, data = data)## R2_marginal R2_conditional
## 0.7137822 1.0000000eval(metafor:::.MuMIn) # use eval() function to extract helper functions from MuMIn and make them usable in metafor.
mlmr.dredge.lnRR <- dredge(mlmr.full.lnRR, beta = "none", evaluate = TRUE, rank = "AICc", trace=2)##
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|===================================================================== | 99%# save to save time - running this model is time-consuming
saveRDS(mlmr.dredge.lnRR, file = "mlmr.dredge.lnRR.Rds")
mlmr.dredge.lnRR <- readRDS(file = "mlmr.dredge.lnRR.Rds")
save(mlmr.dredge.lnRR, file = "mlmr.dredge.lnRR.Rdata")
load(here("R.data", "mlmr.dredge.lnRR.Rdata"))
# multimodel inference
summary(mlmr.full.lnRR)##
## Multivariate Meta-Analysis Model (k = 281; method: ML)
##
## logLik Deviance AIC BIC AICc
## -74.4430 684.7398 220.8860 351.8668 231.8040
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 28 no study_id
## sigma^2.2 0.0487 0.2207 281 no assay_id
## sigma^2.3 0.0000 0.0000 8 no species_latin
## sigma^2.4 0.0000 0.0000 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 249) = 1428.3135, p-val < .0001
##
## Test of Moderators (coefficients 2:32):
## F(df1 = 31, df2 = 249) = 6.6242, p-val < .0001
##
## Model Results:
##
## estimate se tval
## intrcpt -0.8067 0.3634 -2.2200
## behaviour_measured_standardisedcollective behaviour 2.3242 0.7374 3.1520
## behaviour_measured_standardisedcourtship -0.0672 0.1025 -0.6553
## behaviour_measured_standardisedsociality -0.0794 0.0578 -1.3745
## behavioural_assay_standardised2entry -0.1847 0.1426 -1.2948
## behavioural_assay_standardised2zone -0.0563 0.0628 -0.8970
## pesticide_chemical_classcarbamate -1.0406 0.3319 -3.1353
## pesticide_chemical_classneonicotinoid 0.2983 0.2057 1.4505
## pesticide_chemical_classorganochlorine -0.1451 0.2497 -0.5813
## pesticide_chemical_classorganophosphate -0.4643 0.1958 -2.3708
## pesticide_chemical_classphenoxy -0.3825 0.3003 -1.2739
## pesticide_chemical_classpyrethroid -0.0307 0.2119 -0.1448
## pesticide_chemical_classrotenones 0.8495 0.3279 2.5910
## pesticide_chemical_classtriazine 0.0417 0.2913 0.1431
## pesticide_chemical_classtriazole -0.4696 0.2073 -2.2655
## pesticide_chemical_classurea 0.4112 0.3158 1.3020
## control_solventDMSO 1.3869 0.6323 2.1934
## control_solventDTNB 0.5286 0.2749 1.9232
## control_solventnone 1.1764 0.6257 1.8801
## control_solventnot reported 1.5010 0.6373 2.3552
## species_latinDanio rerio -0.2626 0.5797 -0.4530
## species_latinJenynsia multidentata -0.5058 0.6044 -0.8368
## species_latinOryzias latipes -0.8890 0.6325 -1.4054
## species_latinOryzias melastigma -0.9083 0.6104 -1.4879
## species_latinPoecilia latipinna -0.9875 0.6259 -1.5777
## species_latinPoecilia reticulata -0.7434 0.5916 -1.2566
## sexmale -0.1280 0.0912 -1.4042
## sexmixed 0.0600 0.1214 0.4943
## sexnot reported -0.5319 0.2268 -2.3449
## sourcelaboratory stock from not specified source -0.0903 0.1426 -0.6329
## sourcelabratory stock from wild population 0.1398 0.3458 0.4043
## sourcenot reported 0.2109 0.2681 0.7867
## df pval ci.lb
## intrcpt 249 0.0273 -1.5223
## behaviour_measured_standardisedcollective behaviour 249 0.0018 0.8719
## behaviour_measured_standardisedcourtship 249 0.5129 -0.2691
## behaviour_measured_standardisedsociality 249 0.1705 -0.1932
## behavioural_assay_standardised2entry 249 0.1966 -0.4655
## behavioural_assay_standardised2zone 249 0.3706 -0.1799
## pesticide_chemical_classcarbamate 249 0.0019 -1.6942
## pesticide_chemical_classneonicotinoid 249 0.1482 -0.1068
## pesticide_chemical_classorganochlorine 249 0.5616 -0.6369
## pesticide_chemical_classorganophosphate 249 0.0185 -0.8500
## pesticide_chemical_classphenoxy 249 0.2039 -0.9740
## pesticide_chemical_classpyrethroid 249 0.8850 -0.4480
## pesticide_chemical_classrotenones 249 0.0101 0.2038
## pesticide_chemical_classtriazine 249 0.8863 -0.5320
## pesticide_chemical_classtriazole 249 0.0243 -0.8778
## pesticide_chemical_classurea 249 0.1941 -0.2108
## control_solventDMSO 249 0.0292 0.1416
## control_solventDTNB 249 0.0556 -0.0127
## control_solventnone 249 0.0613 -0.0560
## control_solventnot reported 249 0.0193 0.2458
## species_latinDanio rerio 249 0.6510 -1.4044
## species_latinJenynsia multidentata 249 0.4035 -1.6963
## species_latinOryzias latipes 249 0.1612 -2.1348
## species_latinOryzias melastigma 249 0.1380 -2.1105
## species_latinPoecilia latipinna 249 0.1159 -2.2202
## species_latinPoecilia reticulata 249 0.2101 -1.9087
## sexmale 249 0.1615 -0.3075
## sexmixed 249 0.6216 -0.1791
## sexnot reported 249 0.0198 -0.9787
## sourcelaboratory stock from not specified source 249 0.5274 -0.3712
## sourcelabratory stock from wild population 249 0.6863 -0.5413
## sourcenot reported 249 0.4322 -0.3171
## ci.ub
## intrcpt -0.0910 *
## behaviour_measured_standardisedcollective behaviour 3.7765 **
## behaviour_measured_standardisedcourtship 0.1347
## behaviour_measured_standardisedsociality 0.0344
## behavioural_assay_standardised2entry 0.0962
## behavioural_assay_standardised2zone 0.0673
## pesticide_chemical_classcarbamate -0.3869 **
## pesticide_chemical_classneonicotinoid 0.7034
## pesticide_chemical_classorganochlorine 0.3466
## pesticide_chemical_classorganophosphate -0.0786 *
## pesticide_chemical_classphenoxy 0.2089
## pesticide_chemical_classpyrethroid 0.3866
## pesticide_chemical_classrotenones 1.4953 *
## pesticide_chemical_classtriazine 0.6153
## pesticide_chemical_classtriazole -0.0613 *
## pesticide_chemical_classurea 1.0331
## control_solventDMSO 2.6323 *
## control_solventDTNB 1.0700 .
## control_solventnone 2.4089 .
## control_solventnot reported 2.7562 *
## species_latinDanio rerio 0.8792
## species_latinJenynsia multidentata 0.6847
## species_latinOryzias latipes 0.3569
## species_latinOryzias melastigma 0.2940
## species_latinPoecilia latipinna 0.2452
## species_latinPoecilia reticulata 0.4218
## sexmale 0.0515
## sexmixed 0.2991
## sexnot reported -0.0851 *
## sourcelaboratory stock from not specified source 0.1906
## sourcelabratory stock from wild population 0.8210
## sourcenot reported 0.7389
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# Select "best" models based on delta <= 2
best_model <- subset(mlmr.dredge.lnRR, delta <= 2, recalc.weights = FALSE)
# Display the results in a scrollable kable table
best_model %>%
kable("html") %>%
kable_styling("bordered", position = "left") %>%
scroll_box(width = "100%", height = "800px")| (Intercept) | behaviour_measured_standardised | behavioural_assay_standardised2 | control_solvent | pesticide_chemical_class | sex | source | species_latin | df | logLik | AICc | delta | weight | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 91 |
|
NA |
|
NA |
|
|
NA |
|
28 | -81.44311 | 225.3307 | 0.0000000 | 0.18744113 |
| 96 |
|
|
|
|
|
|
NA |
|
33 | -75.22067 | 225.5264 | 0.1956908 | 0.16996957 |
| 27 |
|
NA |
|
NA |
|
|
NA | NA | 21 | -90.08880 | 225.7452 | 0.4145041 | 0.15235491 |
| 31 |
|
NA |
|
|
|
|
NA | NA | 26 | -84.79915 | 227.1259 | 1.7951955 | 0.07639117 |
# the relative importance values for the predictors
weights_lnRR <- sw(mlmr.dredge.lnRR)
# Convert the named vector into a data frame
weights_lnRR_df <- data.frame(
predictor = names(weights_lnRR), # First column: the names of the vector
weight = as.numeric(weights_lnRR) # Second column: the values of the vector
)
weights_lnRR_df %>% ggplot(aes(x = reorder(predictor, weight), y = weight), fill = "lightgrey") +
geom_col(aes(), width = 0.7) +
#scale_fill_manual(values = cols) +
coord_flip() +
labs(y = "Akaike weights", x = "Moderator variables", title = "") +
#ylim(0,1)+
scale_y_continuous(expand = expansion(mult = c(0, 0.2))) +
#coord_cartesian(ylim = c(0,1)) +
geom_text(aes(label=scales::percent(weight, accuracy = 1)), size = 3, position = position_stack(vjust = 0.5), color = "white", fontface = "bold") +
theme(legend.position = "none",
panel.grid = element_blank(),
panel.border = element_blank(),
panel.background = element_blank(),
axis.text.y = element_text(size = 12, color = "black"),
axis.title.y = element_text(size = 12, color = "black"),
axis.ticks.y = element_blank(),
axis.line.x = element_line(colour = "black")) +
scale_x_discrete(labels = c("Source of fish", "Behaviour measured","Control Solvent","Species","Sex of fish","Pesticide chemical class","Behavioural assay"))
## null device
## 1mlmr.full.lnVR <- rma.mv(yi = lnVR,
V = lnVRVCV,
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
mods = ~ behaviour_measured_standardised + behavioural_assay_standardised2 + pesticide_chemical_class + control_solvent +
species_latin + sex + source,
method = "ML",
test = "t",
data = data,
sparse = TRUE)
r2_ml(mlmr.full.lnVR, data = data)## R2_marginal R2_conditional
## 0.3057053 1.0000000eval(metafor:::.MuMIn) # use eval() to extract helper functions from MuMIn and make them usable in metafor.
mlmr.dredge.lnVR <- dredge(mlmr.full.lnVR, beta = "none", evaluate = TRUE, rank = "AICc", trace = 2)##
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|===================================================================== | 99%# Save to save time - running this model is time-consuming
saveRDS(mlmr.dredge.lnVR, file = "mlmr.dredge.lnVR.Rds")
mlmr.dredge.lnVR <- readRDS(file = "mlmr.dredge.lnVR.Rds")
save(mlmr.dredge.lnVR, file = "mlmr.dredge.lnVR.Rdata")
load(here("R.data", "mlmr.dredge.lnVR.Rdata"))
# Multimodel inference
summary(mlmr.full.lnVR)##
## Multivariate Meta-Analysis Model (k = 281; method: ML)
##
## logLik Deviance AIC BIC AICc
## -178.5601 744.7362 429.1203 560.1010 440.0383
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 28 no study_id
## sigma^2.2 0.1513 0.3889 281 no assay_id
## sigma^2.3 0.0000 0.0000 8 no species_latin
## sigma^2.4 0.0000 0.0000 24 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 249) = 1653.7460, p-val < .0001
##
## Test of Moderators (coefficients 2:32):
## F(df1 = 31, df2 = 249) = 2.3438, p-val = 0.0002
##
## Model Results:
##
## estimate se tval
## intrcpt -0.5212 0.5528 -0.9429
## behaviour_measured_standardisedcollective behaviour 1.7008 0.9384 1.8125
## behaviour_measured_standardisedcourtship -0.1397 0.1662 -0.8406
## behaviour_measured_standardisedsociality 0.2057 0.0938 2.1937
## behavioural_assay_standardised2entry -0.7415 0.2474 -2.9974
## behavioural_assay_standardised2zone -0.1314 0.1036 -1.2674
## pesticide_chemical_classcarbamate -1.4219 0.5286 -2.6900
## pesticide_chemical_classneonicotinoid -0.9036 0.3839 -2.3536
## pesticide_chemical_classorganochlorine -0.7255 0.4355 -1.6660
## pesticide_chemical_classorganophosphate -0.8423 0.3542 -2.3780
## pesticide_chemical_classphenoxy -0.8139 0.4923 -1.6530
## pesticide_chemical_classpyrethroid -0.8233 0.3506 -2.3486
## pesticide_chemical_classrotenones -0.3742 0.5849 -0.6397
## pesticide_chemical_classtriazine -1.1221 0.4746 -2.3643
## pesticide_chemical_classtriazole -1.1803 0.3715 -3.1776
## pesticide_chemical_classurea -0.6448 0.4746 -1.3586
## control_solventDMSO 1.3370 0.6118 2.1852
## control_solventDTNB -0.6131 0.5973 -1.0264
## control_solventnone 1.3193 0.5919 2.2289
## control_solventnot reported 1.5943 0.6264 2.5454
## species_latinDanio rerio -0.2083 0.5482 -0.3801
## species_latinJenynsia multidentata -0.6283 0.6021 -1.0435
## species_latinOryzias latipes -0.6320 0.6557 -0.9638
## species_latinOryzias melastigma -0.5757 0.6028 -0.9550
## species_latinPoecilia latipinna -1.1071 0.6729 -1.6453
## species_latinPoecilia reticulata -0.6527 0.5966 -1.0940
## sexmale 0.2694 0.1668 1.6146
## sexmixed 0.1489 0.2146 0.6937
## sexnot reported -0.0899 0.4190 -0.2145
## sourcelaboratory stock from not specified source 0.1181 0.1687 0.7000
## sourcelabratory stock from wild population 1.2487 0.5115 2.4413
## sourcenot reported 0.1269 0.4073 0.3116
## df pval ci.lb
## intrcpt 249 0.3466 -1.6099
## behaviour_measured_standardisedcollective behaviour 249 0.0711 -0.1474
## behaviour_measured_standardisedcourtship 249 0.4014 -0.4671
## behaviour_measured_standardisedsociality 249 0.0292 0.0210
## behavioural_assay_standardised2entry 249 0.0030 -1.2288
## behavioural_assay_standardised2zone 249 0.2062 -0.3355
## pesticide_chemical_classcarbamate 249 0.0076 -2.4630
## pesticide_chemical_classneonicotinoid 249 0.0194 -1.6597
## pesticide_chemical_classorganochlorine 249 0.0970 -1.5832
## pesticide_chemical_classorganophosphate 249 0.0182 -1.5399
## pesticide_chemical_classphenoxy 249 0.0996 -1.7835
## pesticide_chemical_classpyrethroid 249 0.0196 -1.5138
## pesticide_chemical_classrotenones 249 0.5230 -1.5262
## pesticide_chemical_classtriazine 249 0.0188 -2.0569
## pesticide_chemical_classtriazole 249 0.0017 -1.9119
## pesticide_chemical_classurea 249 0.1755 -1.5796
## control_solventDMSO 249 0.0298 0.1320
## control_solventDTNB 249 0.3057 -1.7895
## control_solventnone 249 0.0267 0.1535
## control_solventnot reported 249 0.0115 0.3607
## species_latinDanio rerio 249 0.7042 -1.2880
## species_latinJenynsia multidentata 249 0.2977 -1.8140
## species_latinOryzias latipes 249 0.3361 -1.9234
## species_latinOryzias melastigma 249 0.3405 -1.7628
## species_latinPoecilia latipinna 249 0.1012 -2.4324
## species_latinPoecilia reticulata 249 0.2750 -1.8277
## sexmale 249 0.1077 -0.0592
## sexmixed 249 0.4885 -0.2738
## sexnot reported 249 0.8304 -0.9151
## sourcelaboratory stock from not specified source 249 0.4846 -0.2141
## sourcelabratory stock from wild population 249 0.0153 0.2413
## sourcenot reported 249 0.7556 -0.6752
## ci.ub
## intrcpt 0.5675
## behaviour_measured_standardisedcollective behaviour 3.5489 .
## behaviour_measured_standardisedcourtship 0.1876
## behaviour_measured_standardisedsociality 0.3905 *
## behavioural_assay_standardised2entry -0.2543 **
## behavioural_assay_standardised2zone 0.0728
## pesticide_chemical_classcarbamate -0.3808 **
## pesticide_chemical_classneonicotinoid -0.1474 *
## pesticide_chemical_classorganochlorine 0.1322 .
## pesticide_chemical_classorganophosphate -0.1447 *
## pesticide_chemical_classphenoxy 0.1558 .
## pesticide_chemical_classpyrethroid -0.1329 *
## pesticide_chemical_classrotenones 0.7779
## pesticide_chemical_classtriazine -0.1873 *
## pesticide_chemical_classtriazole -0.4487 **
## pesticide_chemical_classurea 0.2900
## control_solventDMSO 2.5420 *
## control_solventDTNB 0.5634
## control_solventnone 2.4851 *
## control_solventnot reported 2.8280 *
## species_latinDanio rerio 0.8713
## species_latinJenynsia multidentata 0.5575
## species_latinOryzias latipes 0.6595
## species_latinOryzias melastigma 0.6115
## species_latinPoecilia latipinna 0.2182
## species_latinPoecilia reticulata 0.5224
## sexmale 0.5980
## sexmixed 0.5716
## sexnot reported 0.7354
## sourcelaboratory stock from not specified source 0.4503
## sourcelabratory stock from wild population 2.2561 *
## sourcenot reported 0.9290
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1# Select "best" models based on delta <= 2
best_model_vr <- subset(mlmr.dredge.lnVR, delta <= 2, recalc.weights = FALSE)
# Display the results in a scrollable kable table
best_model_vr %>%
kable("html") %>%
kable_styling("bordered", position = "left") %>%
scroll_box(width = "100%", height = "800px")| (Intercept) | behaviour_measured_standardised | behavioural_assay_standardised2 | control_solvent | pesticide_chemical_class | sex | source | species_latin | df | logLik | AICc | delta | weight | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 75 |
|
NA |
|
NA |
|
NA | NA |
|
24 | -186.3893 | 425.4661 | 0.0000000 | 0.2151998 |
| 3 |
|
NA |
|
NA | NA | NA | NA | NA | 7 | -205.8819 | 426.1741 | 0.7080489 | 0.1510397 |
| 67 |
|
NA |
|
NA | NA | NA | NA |
|
14 | -198.7007 | 426.9804 | 1.5142974 | 0.1009291 |
# Relative importance values for the predictors
weights_lnVR <- sw(mlmr.dredge.lnVR)
# Convert the named vector into a data frame
weights_lnVR_df <- data.frame(
predictor = names(weights_lnVR), # First column: the names of the vector
weight = as.numeric(weights_lnVR) # Second column: the values of the vector
)
weights_lnVR_df %>% ggplot(aes(x = reorder(predictor, weight), y = weight), fill = "lightgrey") +
geom_col(aes(), width = 0.7) +
coord_flip() +
labs(y = "Akaike weights", x = "Moderator variables", title = "") +
scale_y_continuous(expand = expansion(mult = c(0, 0.2))) +
geom_text(aes(label = scales::percent(weight, accuracy = 1)), size = 3, position = position_stack(vjust = 0.5), color = "white", fontface = "bold") +
theme(legend.position = "none",
panel.grid = element_blank(),
panel.border = element_blank(),
panel.background = element_blank(),
axis.text.y = element_text(size = 12, color = "black"),
axis.title.y = element_text(size = 12, color = "black"),
axis.ticks.y = element_blank(),
axis.line.x = element_line(colour = "black")) +
scale_x_discrete(labels = c("Source of fish", "Behaviour measured","Control Solvent","Species","Sex of fish","Pesticide chemical class","Behavioural assay"))
## null device
## 1Publication bias
Funnel plot
# Create the funnel plot with adjustments
funnel.1 <- funnel(lnRR_intercept_only,
yaxis = "seinv", # Inverse of standard error (precision) as the y axis
level = c(95), # levels of statistical significance highlighted
shade = c("white"), # shades for different levels of statistical significance
legend = FALSE, # display legend
pch = 21,
refline = 0,
ylab = "Precision (1/SE)") 
Time lag bias
data$pub_year <- str_extract(data$study_id, "\\d{4}")
data$pub_year <- as.numeric(data$pub_year)
time_lag_bias_model <- rma.mv(yi = lnRR, V = lnRRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~pub_year - 1, method = "REML",
test = "t", data = data, sparse = T)
summary(time_lag_bias_model)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -169.4025 338.8050 348.8050 369.3178 348.9411
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0533 0.2309 37 no study_id
## sigma^2.2 0.0582 0.2412 448 no assay_id
## sigma^2.3 0.0615 0.2479 10 no species_latin
## sigma^2.4 0.0080 0.0896 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 447) = 5126.5893, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## pub_year -0.0001 0.0001 -2.3785 447 0.0178 -0.0002 -0.0000 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1lnRR_mod_time_lag_results <- mod_results(time_lag_bias_model, mod = "pub_year", data = data,
group = "study_id") # For prediction intervals
r2_lnRR_time_lag <- r2_ml(time_lag_bias_model, data)
# Calculate R^2 value
r2_lnRR_time_lag <- r2_ml(time_lag_bias_model, data)
# Get the minimum year for x-axis limit
min_year <- min(data$pub_year, na.rm = TRUE)
# Create the bubble plot
bubble_plot(lnRR_mod_time_lag_results, mod = "pub_year", group = "study_id", data = data,
x = "pub_year", y = "lnRR", est.lwd = 1, legend.pos = "bottom.right", k.pos = "bottom.left",
ci.col = "red", pi.col = "black", est.col = "black", g = TRUE) + annotate(geom = "text",
x = min_year + 2, y = max(data$lnRR, na.rm = TRUE) + 0.2, label = paste0("italic(R)^{2} ==",
round(r2_lnRR_time_lag[1], 4)), color = "black", parse = TRUE, size = 4) +
ggtitle("") + theme(plot.title = element_text(size = 18), legend.position = "none",
axis.title.x = element_text(size = 16), axis.title.y = element_text(size = 16),
axis.text.y = element_text(size = 14), axis.text.x = element_text(size = 14)) +
xlab("Publication Year") + scale_x_continuous(limits = c(min_year, max(data$pub_year,
na.rm = TRUE)))
Heteroscadacity check
qplot(y = sqrt(residuals(time_lag_bias_model)^2), x = fitted(time_lag_bias_model)) + # plot sqrt(residuals^2) against fitted values
geom_point() +
geom_smooth(method = "lm") + # method ="lm" to generate a straight line
geom_hline(yintercept = 0, colour="red") 
Egger’s regression
eggers_regression <- rma.mv(yi = lnRR,
V = lnRRVCV,
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
mods = ~sqrt(lnRRv) ,
method = "REML",
test = "t",
data = data,
sparse = T)
summary(eggers_regression)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -168.4319 336.8637 348.8637 373.4657 349.0551
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0535 0.2313 37 no study_id
## sigma^2.2 0.0582 0.2412 448 no assay_id
## sigma^2.3 0.0613 0.2476 10 no species_latin
## sigma^2.4 0.0091 0.0956 30 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 446) = 4961.4465, p-val < .0001
##
## Test of Moderators (coefficient 2):
## F(df1 = 1, df2 = 446) = 0.1718, p-val = 0.6787
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## intrcpt -0.2531 0.1183 -2.1407 446 0.0328 -0.4856 -0.0207 *
## sqrt(lnRRv) -0.0809 0.1950 -0.4145 446 0.6787 -0.4642 0.3025
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1egger_pred <- predict.rma(eggers_regression)
data %>% mutate(fit=egger_pred$pred,
ci.lb=egger_pred$ci.lb,
ci.ub=egger_pred$ci.ub,
pr.lb=egger_pred$cr.lb,
pr.ub=egger_pred$cr.ub) %>%
ggplot(aes(x = sqrt(lnRRv), y = lnRR)) +
geom_ribbon(aes(ymin = pr.lb, ymax = pr.ub, color = NULL), alpha = .1) +
geom_ribbon(aes(ymin = ci.lb, ymax = ci.ub, color = NULL), alpha = .3) +
geom_point(size=2,shape=21, alpha=0.7, fill=RColorBrewer::brewer.pal(n = 8, name = "Dark2")[1], col="gray25",stroke=1) +
geom_line(aes(y = fit), size = 1.2)+
labs(x = "Standard error", y = "lnRR") +
theme_bw() +
geom_hline(yintercept = 0,linetype = 2, colour = "black",alpha=0.5)+ # horizontal line at lnRR = 0
theme(text = element_text(size = 18, colour = "black", hjust = 0.5), # change font sizes and legend position
legend.text=element_text(size=14),
legend.position=c(0,0),
legend.justification = c(0,0),
legend.background = element_blank(),
legend.direction="horizontal",
legend.title = element_text(size=15),
panel.border=element_rect(colour="black", fill=NA, size=1.2))
Sensitivity Analysis
Leave-one-out analysis
Leave one study out
Intercept only model (lnRR)
data$leave_study <- as.factor(data$study_id)
### create a list to contain model estimates
leave_study_out_model_lnRR <- list()
VCV_leave_study_out_lnRR <- list()
### repeatedly run the multilevel model, leaving out one study at a time
for(i in 1:length(levels(data$leave_study))){
### create the data with one study removed at a time
data_study_leave <- data %>% filter(leave_study != levels(data$leave_study)[i])
### create a list of VCV matrices for following model fitting
VCV_leave_study_out_lnRR[[i]] <- impute_covariance_matrix(vi = data_study_leave$lnRRv, cluster = data_study_leave$study_id, r = 0.5)
### model fitting
leave_study_out_model_lnRR[[i]] <- rma.mv(yi = lnRR, V = VCV_leave_study_out_lnRR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_study_leave,
sparse = TRUE)
}
results.leave_study_out_model_lnRR <- as.data.frame(cbind(
sapply(leave_study_out_model_lnRR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_study_out_model_lnRR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_study_out_model_lnRR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_study_out_model_lnRR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_study_out_model_lnRR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_study_out_model_lnRR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_study_out_model_lnRR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub")
results.leave_study_out_model_lnRR$study_id <- unique(data$study_id)
# Display the results table
kable(results.leave_study_out_model_lnRR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | study_id |
|---|---|---|---|---|---|---|
| -0.2707502 | 0.1234745 | -2.192762 | 0.0288415 | -0.5134157 | -0.0280847 | bellot_2024 |
| -0.2222167 | 0.1243949 | -1.786382 | 0.0747197 | -0.4666926 | 0.0222591 | boscolo_2018 |
| -0.2809559 | 0.1226510 | -2.290694 | 0.0224586 | -0.5220181 | -0.0398937 | bridi_2017 |
| -0.2708383 | 0.1246354 | -2.173045 | 0.0303123 | -0.5157962 | -0.0258805 | chen_2022 |
| -0.2732013 | 0.1265705 | -2.158491 | 0.0314286 | -0.5219577 | -0.0244449 | chung_2023 |
| -0.2800641 | 0.1204502 | -2.325144 | 0.0205152 | -0.5167889 | -0.0433392 | faria_2021 |
| -0.2709573 | 0.1229306 | -2.204150 | 0.0280595 | -0.5125981 | -0.0293165 | guo_2023 |
| -0.2720410 | 0.1228927 | -2.213648 | 0.0273711 | -0.5135782 | -0.0305038 | gusso_2020 |
| -0.2603531 | 0.1219030 | -2.135739 | 0.0332496 | -0.4999347 | -0.0207715 | hawkey_2020 |
| -0.2727462 | 0.1231186 | -2.215313 | 0.0272523 | -0.5147229 | -0.0307696 | hawkey_2021 |
| -0.2549523 | 0.1269547 | -2.008215 | 0.0452325 | -0.5044668 | -0.0054378 | hued_2011 |
| -0.2721784 | 0.1231900 | -2.209419 | 0.0276731 | -0.5143095 | -0.0300473 | hussian_2020 |
| -0.2691936 | 0.1225617 | -2.196393 | 0.0286020 | -0.5100945 | -0.0282927 | ilie_2021 |
| -0.2706325 | 0.1212735 | -2.231588 | 0.0261474 | -0.5089827 | -0.0322822 | ilie_2022 |
| -0.2779020 | 0.1274424 | -2.180609 | 0.0297366 | -0.5283672 | -0.0274367 | jaensson_2007 |
| -0.2939646 | 0.1258517 | -2.335802 | 0.0199531 | -0.5413144 | -0.0466148 | khalil_2013 |
| -0.2714868 | 0.1284528 | -2.113514 | 0.0351309 | -0.5239586 | -0.0190149 | khalil_2017 |
| -0.2706756 | 0.1235775 | -2.190332 | 0.0290267 | -0.5135541 | -0.0277971 | lei_2022 |
| -0.2044138 | 0.0834950 | -2.448217 | 0.0147434 | -0.3685092 | -0.0403184 | leite_2023 |
| -0.2722593 | 0.1233538 | -2.207141 | 0.0278185 | -0.5146937 | -0.0298249 | lin_2024 |
| -0.2692625 | 0.1234724 | -2.180750 | 0.0297261 | -0.5119255 | -0.0265995 | liu_2023 |
| -0.2748595 | 0.1231887 | -2.231207 | 0.0261660 | -0.5169649 | -0.0327541 | liu_2023a |
| -0.2677348 | 0.1377674 | -1.943383 | 0.0526360 | -0.5385325 | 0.0030628 | maclaren_2023 |
| -0.2651540 | 0.1224645 | -2.165151 | 0.0309093 | -0.5058375 | -0.0244705 | oliveira_2024 |
| -0.2891602 | 0.1230881 | -2.349213 | 0.0192485 | -0.5310649 | -0.0472554 | olsen_2020 |
| -0.2733496 | 0.1224296 | -2.232709 | 0.0260637 | -0.5139602 | -0.0327391 | paredes_2019 |
| -0.3064524 | 0.1281710 | -2.390964 | 0.0172344 | -0.5583737 | -0.0545310 | sanchez_2021 |
| -0.2675961 | 0.1230901 | -2.173985 | 0.0302423 | -0.5095183 | -0.0256738 | schmidel_2014 |
| -0.3078426 | 0.1360552 | -2.262630 | 0.0241420 | -0.5752365 | -0.0404488 | shenoy_2012 |
| -0.2381278 | 0.1218354 | -1.954503 | 0.0512675 | -0.4775721 | 0.0013165 | silva_2005 |
| -0.2754738 | 0.1240649 | -2.220401 | 0.0269701 | -0.5193994 | -0.0315483 | stungaru_2019 |
| -0.2691895 | 0.1232759 | -2.183634 | 0.0295131 | -0.5114679 | -0.0269112 | tamagno_2023 |
| -0.2395056 | 0.1216880 | -1.968195 | 0.0496717 | -0.4786660 | -0.0003452 | teather_2001 |
| -0.2615337 | 0.1209303 | -2.162681 | 0.0311418 | -0.4992527 | -0.0238146 | yan_2023 |
| -0.2728711 | 0.1212028 | -2.251360 | 0.0248753 | -0.5111058 | -0.0346363 | yang_2023 |
| -0.2364084 | 0.1157051 | -2.043198 | 0.0416609 | -0.4638463 | -0.0089705 | zaluski_2022 |
| -0.2827246 | 0.1361799 | -2.076111 | 0.0384815 | -0.5503911 | -0.0150582 | zhou_2021 |
leave_one_study_out_lnRR_forest_plot <- ggplot(results.leave_study_out_model_lnRR,
aes(x = fct_reorder(as.factor(study_id), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.5) +
labs(caption = "The value in each point is the point estimate excluding one study at a time",
x = "Study ID",
y = "Estimate") +
coord_flip()
print(leave_one_study_out_lnRR_forest_plot)
results.leave_study_out_model_lnRR %>%
summarise(estimate = mean(Estimate), # calculate the mean coefficients across the models generated
se = mean(SE),
zval = mean(zval),
pval = mean(pval),
ci.lb = mean(ci.lb),
ci.ub = mean(ci.ub)) %>%
kable() %>% kable_styling("striped", position = "left")| estimate | se | zval | pval | ci.lb | ci.ub |
|---|---|---|---|---|---|
| -0.2683521 | 0.1233455 | -2.178559 | 0.0313033 | -0.5107802 | -0.025924 |
Intercept only model (lnVR)
data$leave_study <- as.factor(data$study_id)
### create a list to contain model estimates
leave_study_out_model_lnVR <- list()
VCV_leave_study_out_lnVR <- list()
### repeatedly run the multilevel model, leaving out one study at a time
for(i in 1:length(levels(data$leave_study))){
### create the data with one study removed at a time
data_study_leave <- data %>% filter(leave_study != levels(data$leave_study)[i])
### create a list of VCV matrices for following model fitting
VCV_leave_study_out_lnVR[[i]] <- impute_covariance_matrix(vi = data_study_leave$lnVRv, cluster = data_study_leave$study_id, r = 0.5)
### model fitting
leave_study_out_model_lnVR[[i]] <- rma.mv(yi = lnVR, V = VCV_leave_study_out_lnVR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_study_leave,
sparse = TRUE)
}
results.leave_study_out_model_lnVR <- as.data.frame(cbind(
sapply(leave_study_out_model_lnVR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_study_out_model_lnVR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_study_out_model_lnVR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_study_out_model_lnVR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_study_out_model_lnVR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_study_out_model_lnVR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_study_out_model_lnVR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub")
results.leave_study_out_model_lnVR$study_id <- unique(data$study_id)
# Display the results table
kable(results.leave_study_out_model_lnVR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | study_id |
|---|---|---|---|---|---|---|
| -0.0671787 | 0.0788471 | -0.8520129 | 0.3946652 | -0.2221376 | 0.0877801 | bellot_2024 |
| -0.0411794 | 0.0445311 | -0.9247341 | 0.3556065 | -0.1286973 | 0.0463385 | boscolo_2018 |
| -0.0619267 | 0.0818085 | -0.7569719 | 0.4494765 | -0.2227158 | 0.0988623 | bridi_2017 |
| -0.0720351 | 0.0767686 | -0.9383406 | 0.3485865 | -0.2229158 | 0.0788456 | chen_2022 |
| -0.0726168 | 0.0764294 | -0.9501163 | 0.3425736 | -0.2228280 | 0.0775943 | chung_2023 |
| -0.0662749 | 0.0792111 | -0.8366870 | 0.4032196 | -0.2219511 | 0.0894013 | faria_2021 |
| -0.0708509 | 0.0832146 | -0.8514232 | 0.3950230 | -0.2344232 | 0.0927215 | guo_2023 |
| -0.0701593 | 0.0765486 | -0.9165331 | 0.3598952 | -0.2206104 | 0.0802918 | gusso_2020 |
| -0.0699782 | 0.0772368 | -0.9060218 | 0.3654179 | -0.2217752 | 0.0818188 | hawkey_2020 |
| -0.0704540 | 0.0767763 | -0.9176535 | 0.3593053 | -0.2213497 | 0.0804417 | hawkey_2021 |
| -0.0621315 | 0.0760990 | -0.8164555 | 0.4146825 | -0.2116952 | 0.0874322 | hued_2011 |
| -0.0661285 | 0.0799800 | -0.8268127 | 0.4088028 | -0.2233299 | 0.0910729 | hussian_2020 |
| -0.0722795 | 0.0767748 | -0.9414482 | 0.3470088 | -0.2231840 | 0.0786251 | ilie_2021 |
| -0.0698979 | 0.0785579 | -0.8897631 | 0.3740816 | -0.2242951 | 0.0844993 | ilie_2022 |
| -0.0518869 | 0.1010469 | -0.5134927 | 0.6078622 | -0.2504765 | 0.1467028 | jaensson_2007 |
| -0.0441695 | 0.0436557 | -1.0117681 | 0.3122088 | -0.1299708 | 0.0416318 | khalil_2013 |
| -0.0746409 | 0.0870785 | -0.8571675 | 0.3918287 | -0.2457923 | 0.0965105 | khalil_2017 |
| -0.0681779 | 0.0780268 | -0.8737754 | 0.3827194 | -0.2215314 | 0.0851756 | lei_2022 |
| -0.0807308 | 0.0880518 | -0.9168563 | 0.3597168 | -0.2537819 | 0.0923203 | leite_2023 |
| -0.0695566 | 0.0775106 | -0.8973824 | 0.3700045 | -0.2218926 | 0.0827794 | lin_2024 |
| -0.0691347 | 0.0777895 | -0.8887409 | 0.3746236 | -0.2220161 | 0.0837467 | liu_2023 |
| -0.0686691 | 0.0780861 | -0.8794029 | 0.3796586 | -0.2221334 | 0.0847951 | liu_2023a |
| -0.1037526 | 0.0730224 | -1.4208321 | 0.1561058 | -0.2472866 | 0.0397814 | maclaren_2023 |
| -0.0648373 | 0.0801198 | -0.8092544 | 0.4188033 | -0.2222993 | 0.0926248 | oliveira_2024 |
| -0.0950481 | 0.0763584 | -1.2447618 | 0.2138730 | -0.2451151 | 0.0550190 | olsen_2020 |
| -0.0685988 | 0.0781455 | -0.8778343 | 0.3805063 | -0.2221779 | 0.0849803 | paredes_2019 |
| -0.0510415 | 0.0749541 | -0.6809698 | 0.4962580 | -0.1983644 | 0.0962815 | sanchez_2021 |
| -0.0708787 | 0.0784105 | -0.9039447 | 0.3665227 | -0.2249872 | 0.0832298 | schmidel_2014 |
| -0.0948764 | 0.0834956 | -1.1363036 | 0.2564438 | -0.2589731 | 0.0692204 | shenoy_2012 |
| -0.0577383 | 0.0908882 | -0.6352675 | 0.5255805 | -0.2363617 | 0.1208851 | silva_2005 |
| -0.0735040 | 0.0700020 | -1.0500266 | 0.2943611 | -0.2111359 | 0.0641279 | stungaru_2019 |
| -0.0698323 | 0.0773919 | -0.9023203 | 0.3673771 | -0.2219331 | 0.0822686 | tamagno_2023 |
| -0.0379155 | 0.0440822 | -0.8601083 | 0.3901967 | -0.1245527 | 0.0487218 | teather_2001 |
| -0.0656020 | 0.0809741 | -0.8101601 | 0.4183170 | -0.2247770 | 0.0935730 | yan_2023 |
| -0.0684593 | 0.0765250 | -0.8946008 | 0.3715093 | -0.2188758 | 0.0819572 | yang_2023 |
| -0.0605799 | 0.0533660 | -1.1351769 | 0.2569533 | -0.1654799 | 0.0443201 | zaluski_2022 |
| -0.0669336 | 0.0974270 | -0.6870133 | 0.4924473 | -0.2584297 | 0.1245625 | zhou_2021 |
leave_one_study_out_lnVR_forest_plot <- ggplot(results.leave_study_out_model_lnVR,
aes(x = fct_reorder(as.factor(study_id), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.5) +
labs(caption = "The value in each point is the point estimate excluding one study at a time",
x = "Study ID",
y = "Estimate") +
coord_flip()
print(leave_one_study_out_lnVR_forest_plot)
results.leave_study_out_model_lnVR %>%
summarise(estimate = mean(Estimate), # calculate the mean coefficients across the models generated
se = mean(SE),
zval = mean(zval),
pval = mean(pval),
ci.lb = mean(ci.lb),
ci.ub = mean(ci.ub)) %>%
kable() %>% kable_styling("striped", position = "left")| estimate | se | zval | pval | ci.lb | ci.ub |
|---|---|---|---|---|---|
| -0.0678285 | 0.0764647 | -0.8976253 | 0.3757357 | -0.2181149 | 0.0824579 |
Leave one species out
Intercept only model (lnRR)
# Convert species_latin to a factor and create a new column for the leave-one-out procedure
data$leave_species <- as.factor(data$species_latin)
# Initialize lists to contain the model estimates and VCV matrices
leave_species_out_model_lnRR <- list()
VCV_leave_species_out_lnRR <- list()
# Iteratively run the multilevel model, leaving out one species at a time
for(i in 1:length(levels(data$leave_species))){
# Create the data with one species removed at a time
data_species_leave <- data %>% filter(leave_species != levels(data$leave_species)[i])
# Create a VCV matrix for the subset data
VCV_leave_species_out_lnRR[[i]] <- impute_covariance_matrix(vi = data_species_leave$lnRRv, cluster = data_species_leave$study_id, r = 0.5)
# Model fitting
leave_species_out_model_lnRR[[i]] <- rma.mv(yi = data_species_leave$lnRR,
V = VCV_leave_species_out_lnRR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_species_leave,
sparse = TRUE)
}
results.leave_species_out_model_lnRR <- as.data.frame(cbind(
sapply(leave_species_out_model_lnRR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_species_out_model_lnRR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_species_out_model_lnRR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_species_out_model_lnRR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_species_out_model_lnRR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_species_out_model_lnRR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_species_out_model_lnRR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub") # change column names
results.leave_species_out_model_lnRR$species_latin <- unique(data$species_latin)
# Display the results table
kable(results.leave_species_out_model_lnRR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | species_latin |
|---|---|---|---|---|---|---|
| -0.1823464 | 0.0783664 | -2.326844 | 0.0204216 | -0.3363605 | -0.0283322 | Danio rerio |
| -0.2931214 | 0.1383311 | -2.118984 | 0.0361534 | -0.5670074 | -0.0192354 | Oreochromis niloticus |
| -0.2948379 | 0.1402541 | -2.102169 | 0.0361319 | -0.5705235 | -0.0191523 | Jenynsia multidentata |
| -0.2715611 | 0.0946959 | -2.867716 | 0.0043309 | -0.4576679 | -0.0854543 | Salmo trutta |
| -0.2222167 | 0.1243949 | -1.786382 | 0.0747197 | -0.4666926 | 0.0222591 | Oryzias latipes |
| -0.2690256 | 0.1417029 | -1.898519 | 0.0583212 | -0.5475706 | 0.0095193 | Luciobarbus bocagei |
| -0.2827246 | 0.1361799 | -2.076111 | 0.0384815 | -0.5503911 | -0.0150582 | Alburnus alburnus |
| -0.2677348 | 0.1377674 | -1.943383 | 0.0526360 | -0.5385325 | 0.0030628 | Poecilia latipinna |
| -0.2516205 | 0.1337990 | -1.880586 | 0.0606871 | -0.5145834 | 0.0113424 | Poecilia reticulata |
| -0.3080645 | 0.1311092 | -2.349680 | 0.0192277 | -0.5657377 | -0.0503913 | Oryzias melastigma |
leave_one_species_out_lnRR_forest_plot <- ggplot(results.leave_species_out_model_lnRR,
aes(x = fct_reorder(as.factor(species_latin), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.3) +
labs(caption = "The value in each point is the estimate excluding one species at a time",
x = "Species Latin",
y = "Estimate") +
coord_flip()
print(leave_one_species_out_lnRR_forest_plot)
Intercept only model (lnVR)
# Convert species_latin to a factor and create a new column for the leave-one-out procedure
data$leave_species <- as.factor(data$species_latin)
# Initialize lists to contain the model estimates and VCV matrices
leave_species_out_model_lnVR <- list()
VCV_leave_species_out_lnVR <- list()
# Iteratively run the multilevel model, leaving out one species at a time
for(i in 1:length(levels(data$leave_species))){
# Create the data with one species removed at a time
data_species_leave <- data %>% filter(leave_species != levels(data$leave_species)[i])
# Create a VCV matrix for the subset data
VCV_leave_species_out_lnVR[[i]] <- impute_covariance_matrix(vi = data_species_leave$lnVRv, cluster = data_species_leave$study_id, r = 0.5)
# Model fitting
leave_species_out_model_lnVR[[i]] <- rma.mv(yi = data_species_leave$lnVR,
V = VCV_leave_species_out_lnVR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_species_leave,
sparse = TRUE)
}
results.leave_species_out_model_lnVR <- as.data.frame(cbind(
sapply(leave_species_out_model_lnVR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_species_out_model_lnVR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_species_out_model_lnVR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_species_out_model_lnVR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_species_out_model_lnVR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_species_out_model_lnVR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_species_out_model_lnVR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub") # change column names
results.leave_species_out_model_lnVR$species_latin <- unique(data$species_latin)
# Display the results table
kable(results.leave_species_out_model_lnVR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | species_latin |
|---|---|---|---|---|---|---|
| -0.0762239 | 0.0823193 | -0.9259548 | 0.3549713 | -0.2380067 | 0.0855589 | Danio rerio |
| -0.1512107 | 0.1171878 | -1.2903283 | 0.1994175 | -0.3832344 | 0.0808129 | Oreochromis niloticus |
| -0.0388610 | 0.0845842 | -0.4594357 | 0.6461585 | -0.2051210 | 0.1273990 | Jenynsia multidentata |
| -0.0704455 | 0.0832357 | -0.8463376 | 0.3978193 | -0.2340294 | 0.0931384 | Salmo trutta |
| -0.0411794 | 0.0445311 | -0.9247341 | 0.3556065 | -0.1286973 | 0.0463385 | Oryzias latipes |
| -0.0317717 | 0.0443399 | -0.7165478 | 0.4740562 | -0.1189306 | 0.0553872 | Luciobarbus bocagei |
| -0.0669336 | 0.0974270 | -0.6870133 | 0.4924473 | -0.2584297 | 0.1245625 | Alburnus alburnus |
| -0.1037526 | 0.0730224 | -1.4208321 | 0.1561058 | -0.2472866 | 0.0397814 | Poecilia latipinna |
| -0.0873669 | 0.0886485 | -0.9855422 | 0.3248982 | -0.2615929 | 0.0868592 | Poecilia reticulata |
| -0.0911190 | 0.0803211 | -1.1344338 | 0.2572261 | -0.2489769 | 0.0667388 | Oryzias melastigma |
leave_one_species_out_lnVR_forest_plot <- ggplot(results.leave_species_out_model_lnVR,
aes(x = fct_reorder(as.factor(species_latin), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.3) +
labs(caption = "The value in each point is the estimate excluding one species at a time",
x = "Species Latin",
y = "Estimate") +
coord_flip()
print(leave_one_species_out_lnVR_forest_plot)
Leave one pesticide out
Intercept only model (lnRR)
# Convert pesticide_chemical_class to a factor and create a new column for the leave-one-out procedure
data$leave_pesticide <- as.factor(data$pesticide_chemical_class)
# Initialize lists to contain the model estimates and VCV matrices
leave_pesticide_out_model_lnRR <- list()
VCV_leave_pesticide_out_lnRR <- list()
# Iteratively run the multilevel model, leaving out one pesticide chemical class at a time
for(i in 1:length(levels(data$leave_pesticide))){
# Create the data with one pesticide removed at a time
data_pesticide_leave <- data %>% filter(leave_pesticide != levels(data$leave_pesticide)[i])
# Create a VCV matrix for the subset data
VCV_leave_pesticide_out_lnRR[[i]] <- impute_covariance_matrix(vi = data_pesticide_leave$lnRRv, cluster = data_pesticide_leave$study_id, r = 0.5)
# Model fitting
leave_pesticide_out_model_lnRR[[i]] <- rma.mv(yi = data_pesticide_leave$lnRR,
V = VCV_leave_pesticide_out_lnRR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_pesticide_leave,
sparse = TRUE)
}
results.leave_pesticide_out_model_lnRR <- as.data.frame(cbind(
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_pesticide_out_model_lnRR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_pesticide_out_model_lnRR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub") # change column names
results.leave_pesticide_out_model_lnRR$pesticide_chemical_class <- unique(data$pesticide_chemical_class)
# Display the results table
kable(results.leave_pesticide_out_model_lnRR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | pesticide_chemical_class |
|---|---|---|---|---|---|---|
| -0.2709573 | 0.1229306 | -2.204150 | 0.0280595 | -0.5125981 | -0.0293165 | organophosphate |
| -0.2831370 | 0.1229412 | -2.303027 | 0.0217408 | -0.5247590 | -0.0415150 | urea |
| -0.2708383 | 0.1246354 | -2.173045 | 0.0303123 | -0.5157962 | -0.0258805 | dioxolanes |
| -0.2784144 | 0.1262790 | -2.204756 | 0.0280205 | -0.5266424 | -0.0301864 | neonicotinoid |
| -0.2764455 | 0.1267305 | -2.181365 | 0.0296936 | -0.5255289 | -0.0273621 | B-methoxyacrylates |
| -0.3388205 | 0.1528384 | -2.216855 | 0.0272420 | -0.6393639 | -0.0382771 | phenoxy |
| -0.2695460 | 0.1222705 | -2.204505 | 0.0280010 | -0.5098469 | -0.0292452 | organochlorine |
| -0.2720410 | 0.1228927 | -2.213648 | 0.0273711 | -0.5135782 | -0.0305038 | organophosphate and organochlorine |
| -0.2149606 | 0.0925602 | -2.322387 | 0.0207630 | -0.3969804 | -0.0329407 | triazole |
| -0.2741606 | 0.1211721 | -2.262573 | 0.0241758 | -0.5123448 | -0.0359764 | rotenones |
| -0.2697352 | 0.1491096 | -1.808973 | 0.0712212 | -0.5628898 | 0.0234194 | pyrethroid |
| -0.2568284 | 0.1202154 | -2.136401 | 0.0332703 | -0.4931817 | -0.0204751 | triazine |
| -0.2401524 | 0.1352142 | -1.776088 | 0.0764618 | -0.5059539 | 0.0256492 | carbamate |
leave_one_pesticide_out_lnRR_forest_plot <- ggplot(results.leave_pesticide_out_model_lnRR,
aes(x = fct_reorder(as.factor(pesticide_chemical_class), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.3) +
labs(caption = "The value in each point is the estimate excluding one pesticide at a time",
x = "Pesticide Chemical Class",
y = "Estimate") +
coord_flip()
print(leave_one_pesticide_out_lnRR_forest_plot)
Intercept only model (lnVR)
# Convert pesticide_chemical_class to a factor and create a new column for the leave-one-out procedure
data$leave_pesticide <- as.factor(data$pesticide_chemical_class)
# Initialize lists to contain the model estimates and VCV matrices
leave_pesticide_out_model_lnVR <- list()
VCV_leave_pesticide_out_lnVR <- list()
# Iteratively run the multilevel model, leaving out one pesticide chemical class at a time
for(i in 1:length(levels(data$leave_pesticide))){
# Create the data with one pesticide removed at a time
data_pesticide_leave <- data %>% filter(leave_pesticide != levels(data$leave_pesticide)[i])
# Create a VCV matrix for the subset data
VCV_leave_pesticide_out_lnVR[[i]] <- impute_covariance_matrix(vi = data_pesticide_leave$lnVRv, cluster = data_pesticide_leave$study_id, r = 0.5)
# Model fitting
leave_pesticide_out_model_lnVR[[i]] <- rma.mv(yi = data_pesticide_leave$lnVR,
V = VCV_leave_pesticide_out_lnVR[[i]],
random = list(~1 | study_id,
~1 | assay_id,
~1 | species_latin,
~1 | pesticide),
method = "REML",
test = "t",
data = data_pesticide_leave,
sparse = TRUE)
}
results.leave_pesticide_out_model_lnVR <- as.data.frame(cbind(
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$beta), # extract the beta coefficient from all models
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$se), # extract the standard error from all models
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$zval), # extract the z value from all models
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$pval), # extract the p value from all models
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$ci.lb),# extract the lower confidence interval for all models
sapply(leave_pesticide_out_model_lnVR, function(x) summary(x)$ci.ub) # extract the upper confidence interval for all models
))
colnames(results.leave_pesticide_out_model_lnVR) <- c("Estimate", "SE", "zval", "pval", "ci.lb", "ci.ub") # change column names
results.leave_pesticide_out_model_lnVR$pesticide_chemical_class <- unique(data$pesticide_chemical_class)
# Display the results table
kable(results.leave_pesticide_out_model_lnVR) %>%
kable_styling("striped", position = "left") %>%
scroll_box(width = "100%", height = "500px")| Estimate | SE | zval | pval | ci.lb | ci.ub | pesticide_chemical_class |
|---|---|---|---|---|---|---|
| -0.0708509 | 0.0832146 | -0.8514232 | 0.3950230 | -0.2344232 | 0.0927215 | organophosphate |
| -0.0923824 | 0.0788418 | -1.1717441 | 0.2419311 | -0.2473338 | 0.0625690 | urea |
| -0.0720351 | 0.0767686 | -0.9383406 | 0.3485865 | -0.2229158 | 0.0788456 | dioxolanes |
| -0.0725936 | 0.0742223 | -0.9780566 | 0.3286175 | -0.2184932 | 0.0733060 | neonicotinoid |
| -0.0737633 | 0.0811302 | -0.9091967 | 0.3637521 | -0.2332212 | 0.0856946 | B-methoxyacrylates |
| 0.0024225 | 0.0935039 | 0.0259081 | 0.9793447 | -0.1814449 | 0.1862899 | phenoxy |
| -0.0687994 | 0.0779251 | -0.8828923 | 0.3777722 | -0.2219472 | 0.0843483 | organochlorine |
| -0.0701593 | 0.0765486 | -0.9165331 | 0.3598952 | -0.2206104 | 0.0802918 | organophosphate and organochlorine |
| -0.0707677 | 0.1088089 | -0.6503850 | 0.5158539 | -0.2847407 | 0.1432053 | triazole |
| -0.0734635 | 0.0774377 | -0.9486786 | 0.3433335 | -0.2256803 | 0.0787534 | rotenones |
| -0.1356974 | 0.0827064 | -1.6407124 | 0.1016592 | -0.2983009 | 0.0269062 | pyrethroid |
| -0.0244357 | 0.0458342 | -0.5331321 | 0.5942466 | -0.1145495 | 0.0656781 | triazine |
| -0.0364973 | 0.0911058 | -0.4006035 | 0.6889212 | -0.2155914 | 0.1425968 | carbamate |
leave_one_pesticide_out_lnVR_forest_plot <- ggplot(results.leave_pesticide_out_model_lnVR,
aes(x = fct_reorder(as.factor(pesticide_chemical_class), Estimate),
y = Estimate,
ymin = ci.lb,
ymax = ci.ub)) +
geom_pointrange() +
geom_hline(yintercept = 0, linetype = "dashed", color = "red") +
theme_bw() +
theme(legend.position = "none",
axis.text = element_text(color = "black"),
axis.title = element_text(face = "bold", color = "black"),
plot.caption = element_text(size = 10, color = "gray10", face = "italic"),
axis.text.y = element_text(size = 8)) +
geom_text(aes(label = round(Estimate, 2)), size = 4, color = "gray10", nudge_x = 0.3) +
labs(caption = "The value in each point is the estimate excluding one pesticide at a time",
x = "Pesticide Chemical Class",
y = "Estimate") +
coord_flip()
print(leave_one_pesticide_out_lnVR_forest_plot)
Alternative effect sizes
Intercept only model (SMD)
# Model
SMD_intercept_only <- rma.mv(yi = SMD, V = SMDVCV, random = list(~1 | study_id, ~1 |
assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t", data = data,
sparse = T)
# Summary statistics
summary(SMD_intercept_only)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -547.2416 1094.4832 1104.4832 1124.9960 1104.6192
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.5339 0.7307 37 no study_id
## sigma^2.2 0.3771 0.6141 448 no assay_id
## sigma^2.3 0.4006 0.6329 10 no species_latin
## sigma^2.4 0.0000 0.0000 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 2954.1806, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.3503 0.2902 -1.2072 447 0.2280 -0.9207 0.2200
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(SMD_intercept_only, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.3503321 -0.9206628 0.2199985 -2.672268 1.971604## I2_Total I2_study_id I2_assay_id I2_species_latin
## 9.245660e+01 3.763523e+01 2.658367e+01 2.823770e+01
## I2_pesticide
## 1.195849e-07# orchaRd plot
orchaRd::orchard_plot(SMD_intercept_only, group = "study_id", xlab = "SMDH", data = data,
k.pos = "right", colour = FALSE, fill = FALSE)
Intercept only model (lnCVR)
# Model
lnCVR_intercept_only <- rma.mv(yi = lnCVR, V = lnCVRVCV, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t",
data = data, sparse = T)
# Summary results
summary(lnCVR_intercept_only)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -347.7776 695.5553 705.5553 726.0681 705.6913
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0207 0.1438 37 no study_id
## sigma^2.2 0.1591 0.3989 448 no assay_id
## sigma^2.3 0.0323 0.1796 10 no species_latin
## sigma^2.4 0.0054 0.0731 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 1797.4539, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## 0.1034 0.0948 1.0904 447 0.2761 -0.0829 0.2897
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnCVR_intercept_only, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt 0.1033815 -0.08294109 0.289704 -0.831791 1.038554## I2_Total I2_study_id I2_assay_id I2_species_latin
## 69.822923 6.641976 51.099832 10.363084
## I2_pesticide
## 1.718031# orchaRd plot
orchaRd::orchard_plot(lnCVR_intercept_only, group = "study_id", xlab = "lnVR", data = data,
k.pos = "right", colour = FALSE, fill = FALSE)
Alternative variance-covariance matrices
Intercept only model (lnRR)
# Model
lnRR_intercept_only2 <- rma.mv(yi = lnRR, V = lnRRVCV2, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t",
data = data, sparse = T)
# Summary statistics
summary(lnRR_intercept_only2)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -169.9073 339.8145 349.8145 370.3273 349.9506
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0547 0.2338 37 no study_id
## sigma^2.2 0.0564 0.2375 448 no assay_id
## sigma^2.3 0.0604 0.2457 10 no species_latin
## sigma^2.4 0.0076 0.0873 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 4339.0531, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2655 0.1111 -2.3886 447 0.0173 -0.4839 -0.0470 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_intercept_only2, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.2654576 -0.4838694 -0.04704575 -1.12539 0.5944748## I2_Total I2_study_id I2_assay_id I2_species_latin
## 97.397072 29.730523 30.685913 32.837521
## I2_pesticide
## 4.143115# orchaRd plot
orchaRd::orchard_plot(lnRR_intercept_only2, group = "study_id", xlab = "lnRR", data = data,
k.pos = "right", colour = FALSE, fill = FALSE)
Intercept only model (lnVR)
# Model
lnVR_intercept_only2 <- rma.mv(yi = lnVR, V = lnVRVCV2, random = list(~1 | study_id,
~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML", test = "t",
data = data, sparse = TRUE)
# Summary results
summary(lnVR_intercept_only2)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -392.0815 784.1630 794.1630 814.6758 794.2990
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0089 0.0945 37 no study_id
## sigma^2.2 0.2454 0.4953 448 no assay_id
## sigma^2.3 0.0353 0.1880 10 no species_latin
## sigma^2.4 0.0024 0.0492 30 no pesticide
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0799 0.0894 -0.8933 447 0.3722 -0.2557 0.0959
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_intercept_only2, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.07990536 -0.2556903 0.09587962 -1.156438 0.9966271## I2_Total I2_study_id I2_assay_id I2_species_latin
## 84.8946375 2.5975924 71.3237081 10.2699094
## I2_pesticide
## 0.7034276# orchaRd plot
orchaRd::orchard_plot(lnVR_intercept_only2, group = "study_id", xlab = "lnVR", data = data,
k.pos = "right", colour = FALSE, fill = FALSE)
Leave studies with imputed errors out
Intercept only model (lnRR)
data_no_imputed <- data %>%
filter(data$control_imputed == "No")
lnRRVCV_no_imputed <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id,
data = data_no_imputed, rho = 0.5)
# Model
lnRR_intercept_only_no_imputed <- rma.mv(yi = lnRR, V = lnRRVCV_no_imputed, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML",
test = "t", data = data_no_imputed, sparse = T)
# Summary statistics
summary(lnRR_intercept_only_no_imputed)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -169.3896 338.7792 348.7792 369.2920 348.9153
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0532 0.2308 37 no study_id
## sigma^2.2 0.0582 0.2412 448 no assay_id
## sigma^2.3 0.0613 0.2477 10 no species_latin
## sigma^2.4 0.0080 0.0897 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 5125.7373, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.2669 0.1119 -2.3862 447 0.0174 -0.4868 -0.0471 *
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_intercept_only_no_imputed, mod = "1", data = data, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.2669384 -0.4867913 -0.04708555 -1.131056 0.597179## I2_Total I2_study_id I2_assay_id I2_species_latin
## 97.420978 28.689981 31.340099 33.054406
## I2_pesticide
## 4.336491# orchaRd plot
orchaRd::orchard_plot(lnRR_intercept_only_no_imputed, group = "study_id", xlab = "lnRR",
data = data, k.pos = "right", colour = FALSE, fill = FALSE)
Intercept only model (lnVR)
# Calculate the variance-covariance matrix for lnVR
lnVRVCV_no_imputed <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id,
data = data_no_imputed, rho = 0.5)
# Model
lnVR_intercept_only_no_imputed <- rma.mv(yi = lnVR, V = lnVRVCV_no_imputed, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML",
test = "t", data = data_no_imputed, sparse = TRUE)
# Summary statistics
summary(lnVR_intercept_only_no_imputed)##
## Multivariate Meta-Analysis Model (k = 448; method: REML)
##
## logLik Deviance AIC BIC AICc
## -390.6297 781.2594 791.2594 811.7722 791.3954
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0088 0.0936 37 no study_id
## sigma^2.2 0.2504 0.5004 448 no assay_id
## sigma^2.3 0.0240 0.1549 10 no species_latin
## sigma^2.4 0.0031 0.0560 30 no pesticide
##
## Test for Heterogeneity:
## Q(df = 447) = 3617.6450, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0848 0.0829 -1.0230 447 0.3069 -0.2477 0.0781
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_intercept_only_no_imputed, mod = "1", data = data_no_imputed, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.08478534 -0.2476678 0.07809708 -1.148797 0.9792265## I2_Total I2_study_id I2_assay_id I2_species_latin
## 84.6352543 2.5876816 74.0269893 7.0938537
## I2_pesticide
## 0.9267297# orchaRd plot
orchaRd::orchard_plot(lnVR_intercept_only_no_imputed, group = "study_id", xlab = "lnVR",
data = data_no_imputed, k.pos = "right", colour = FALSE, fill = FALSE)
Create models with only Zebrafish
Intercept only models (lnRR)
data_zebrafish <- data %>%
filter(species_english == "zebrafish")
lnRRVCV_zebrafish <- metafor::vcalc(vi = lnRRv, cluster = exp_id, obs = assay_id,
data = data_zebrafish, rho = 0.5)
# Model
lnRR_intercept_only_zebrafish <- rma.mv(yi = lnRR, V = lnRRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML",
test = "t", data = data_zebrafish, sparse = T)
# Summary statistics
summary(lnRR_intercept_only_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -110.7715 221.5431 229.5431 244.6907 229.6677
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0477 0.2184 24 no study_id
## sigma^2.2 0.0532 0.2307 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0112 0.1057 21 no pesticide
##
## Test for Heterogeneity:
## Q(df = 326) = 3216.1619, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0288 0.0577 -0.4986 326 0.6184 -0.1423 0.0847
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_intercept_only_zebrafish, mod = "1", data = data_zebrafish, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.02876778 -0.1422657 0.08473014 -0.697124 0.6395884## I2_Total I2_study_id I2_assay_id I2_species_latin
## 96.657410 41.136504 45.885727 0.000000
## I2_pesticide
## 9.635179# orchaRd plot
orchaRd::orchard_plot(lnRR_intercept_only_zebrafish, group = "study_id", xlab = "lnRR",
data = data_zebrafish, k.pos = "right", colour = FALSE, fill = FALSE)
Intercept only models (lnVR)
# Calculate the variance-covariance matrix for lnVR
lnVRVCV_zebrafish <- metafor::vcalc(vi = lnVRv, cluster = exp_id, obs = assay_id,
data = data_zebrafish, rho = 0.5)
# Model
lnVR_intercept_only_zebrafish <- rma.mv(yi = lnVR, V = lnVRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), method = "REML",
test = "t", data = data_zebrafish, sparse = TRUE)
# Summary statistics
summary(lnVR_intercept_only_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -260.5906 521.1813 529.1813 544.3289 529.3059
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 24 no study_id
## sigma^2.2 0.2195 0.4686 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0204 0.1428 21 no pesticide
##
## Test for Heterogeneity:
## Q(df = 326) = 2692.6565, p-val < .0001
##
## Model Results:
##
## estimate se tval df pval ci.lb ci.ub
## -0.0373 0.0525 -0.7110 326 0.4776 -0.1407 0.0660
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_intercept_only_zebrafish, mod = "1", data = data_zebrafish, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Intrcpt -0.03734701 -0.1406764 0.06598238 -1.006519 0.9318252## I2_Total I2_study_id I2_assay_id I2_species_latin
## 8.341099e+01 4.794719e-07 7.631921e+01 0.000000e+00
## I2_pesticide
## 7.091779e+00# orchaRd plot
orchaRd::orchard_plot(lnVR_intercept_only_zebrafish, group = "study_id", xlab = "lnVR",
data = data_zebrafish, k.pos = "right", colour = FALSE, fill = FALSE)
Moderate by behavioural class (lnRR) only including studies using zebrafish
# Model
lnRR_mod_behaviour_class_zebrafish <- rma.mv(yi = lnRR, V = lnRRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behaviour_measured_standardised -
1, method = "REML", test = "t", data = data_zebrafish, sparse = T)
# Summary results
summary(lnRR_mod_behaviour_class_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -89.7825 179.5650 193.5650 220.0086 193.9206
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0522 0.2284 24 no study_id
## sigma^2.2 0.0410 0.2026 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0113 0.1065 21 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 323) = 2355.2416, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 323) = 11.6365, p-val < .0001
##
## Model Results:
##
## estimate se tval
## behaviour_measured_standardisedaggression 0.0747 0.0687 1.0865
## behaviour_measured_standardisedcollective behaviour -0.0313 0.0723 -0.4330
## behaviour_measured_standardisedcourtship -0.3853 0.0905 -4.2587
## behaviour_measured_standardisedsociality -0.0148 0.0702 -0.2104
## df pval ci.lb
## behaviour_measured_standardisedaggression 323 0.2781 -0.0605
## behaviour_measured_standardisedcollective behaviour 323 0.6653 -0.1737
## behaviour_measured_standardisedcourtship 323 <.0001 -0.5633
## behaviour_measured_standardisedsociality 323 0.8335 -0.1529
## ci.ub
## behaviour_measured_standardisedaggression 0.2099
## behaviour_measured_standardisedcollective behaviour 0.1110
## behaviour_measured_standardisedcourtship -0.2073 ***
## behaviour_measured_standardisedsociality 0.1233
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_behaviour_class_zebrafish, mod = "behaviour_measured_standardised",
data = data_zebrafish, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Aggression 0.07468825 -0.06054556 0.2099221 -0.5755789 0.7249554
## 2 Collective behaviour -0.03132611 -0.17366193 0.1110097 -0.6831073 0.6204551
## 3 Courtship -0.38530397 -0.56329626 -0.2073117 -1.0457890 0.2751811
## 4 Sociality -0.01477226 -0.15288161 0.1233371 -0.6656435 0.6360990## R2_marginal R2_conditional
## 0.1331023 0.9059886# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_behaviour_class_zebrafish, group = "pesticide_chemical_class",
xlab = "lnRR", data = data_zebrafish, mod = "behaviour_measured_standardised",
k.pos = "right", colour = TRUE, fill = FALSE)
Moderate by behavioural class (lnVR)
# Model
lnVR_mod_behaviour_class_zebrafish <- rma.mv(yi = lnVR, V = lnVRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~behaviour_measured_standardised -
1, method = "REML", test = "t", data = data_zebrafish, sparse = TRUE)
# Summary results
summary(lnVR_mod_behaviour_class_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -255.6369 511.2739 525.2739 551.7174 525.6294
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0016 0.0402 24 no study_id
## sigma^2.2 0.2079 0.4560 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0456 0.2136 21 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 323) = 2560.0910, p-val < .0001
##
## Test of Moderators (coefficients 1:4):
## F(df1 = 4, df2 = 323) = 2.0836, p-val = 0.0827
##
## Model Results:
##
## estimate se tval
## behaviour_measured_standardisedaggression 0.0310 0.0812 0.3821
## behaviour_measured_standardisedcollective behaviour -0.0178 0.0950 -0.1875
## behaviour_measured_standardisedcourtship -0.3684 0.1436 -2.5656
## behaviour_measured_standardisedsociality -0.0150 0.0907 -0.1659
## df pval ci.lb
## behaviour_measured_standardisedaggression 323 0.7026 -0.1288
## behaviour_measured_standardisedcollective behaviour 323 0.8514 -0.2047
## behaviour_measured_standardisedcourtship 323 0.0108 -0.6509
## behaviour_measured_standardisedsociality 323 0.8684 -0.1935
## ci.ub
## behaviour_measured_standardisedaggression 0.1908
## behaviour_measured_standardisedcollective behaviour 0.1691
## behaviour_measured_standardisedcourtship -0.0859 *
## behaviour_measured_standardisedsociality 0.1634
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_behaviour_class_zebrafish, mod = "behaviour_measured_standardised",
data = data_zebrafish, group = "study_id") # For prediction intervals## name estimate lowerCL upperCL lowerPR upperPR
## 1 Aggression 0.03103547 -0.1287528 0.19082377 -0.9754294 1.0375004
## 2 Collective behaviour -0.01781640 -0.2047318 0.16909895 -1.0289428 0.9933100
## 3 Courtship -0.36842404 -0.6509397 -0.08590835 -1.4015041 0.6646560
## 4 Sociality -0.01504306 -0.1934623 0.16337623 -1.0246334 0.9945473## R2_marginal R2_conditional
## 0.04563426 0.82936645# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_behaviour_class_zebrafish, group = "pesticide_chemical_class",
xlab = "lnVR", data = data_zebrafish, mod = "behaviour_measured_standardised",
k.pos = "right", colour = TRUE, fill = FALSE)
Moderate by pesticide chemical class (lnRR)
# Model
lnRR_mod_pesticide_zebrafish <- rma.mv(yi = lnRR, V = lnRRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~pesticide_chemical_class -
1, method = "REML", test = "t", data = data_zebrafish, sparse = TRUE)
# Summary results
summary(lnRR_mod_pesticide_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -95.7966 191.5932 223.5932 283.5835 225.4248
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0812 0.2850 24 no study_id
## sigma^2.2 0.0517 0.2274 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0000 0.0000 21 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 314) = 2584.1022, p-val < .0001
##
## Test of Moderators (coefficients 1:13):
## F(df1 = 13, df2 = 314) = 1.0999, p-val = 0.3581
##
## Model Results:
##
## estimate se
## pesticide_chemical_classB-methoxyacrylates -0.0608 0.2891
## pesticide_chemical_classcarbamate -0.4496 0.3298
## pesticide_chemical_classdioxolanes -0.1780 0.2972
## pesticide_chemical_classneonicotinoid -0.0378 0.1761
## pesticide_chemical_classorganochlorine -0.1574 0.1727
## pesticide_chemical_classorganophosphate 0.0404 0.1465
## pesticide_chemical_classorganophosphate and organochlorine -0.0826 0.2780
## pesticide_chemical_classphenoxy 0.0024 0.3016
## pesticide_chemical_classpyrethroid -0.0438 0.1578
## pesticide_chemical_classrotenones 0.3895 0.2442
## pesticide_chemical_classtriazine 0.0217 0.2098
## pesticide_chemical_classtriazole -0.1050 0.1935
## pesticide_chemical_classurea 0.4048 0.2476
## tval df
## pesticide_chemical_classB-methoxyacrylates -0.2104 314
## pesticide_chemical_classcarbamate -1.3633 314
## pesticide_chemical_classdioxolanes -0.5990 314
## pesticide_chemical_classneonicotinoid -0.2149 314
## pesticide_chemical_classorganochlorine -0.9114 314
## pesticide_chemical_classorganophosphate 0.2759 314
## pesticide_chemical_classorganophosphate and organochlorine -0.2973 314
## pesticide_chemical_classphenoxy 0.0078 314
## pesticide_chemical_classpyrethroid -0.2774 314
## pesticide_chemical_classrotenones 1.5953 314
## pesticide_chemical_classtriazine 0.1036 314
## pesticide_chemical_classtriazole -0.5426 314
## pesticide_chemical_classurea 1.6349 314
## pval ci.lb
## pesticide_chemical_classB-methoxyacrylates 0.8335 -0.6295
## pesticide_chemical_classcarbamate 0.1738 -1.0984
## pesticide_chemical_classdioxolanes 0.5496 -0.7628
## pesticide_chemical_classneonicotinoid 0.8300 -0.3842
## pesticide_chemical_classorganochlorine 0.3628 -0.4971
## pesticide_chemical_classorganophosphate 0.7828 -0.2479
## pesticide_chemical_classorganophosphate and organochlorine 0.7665 -0.6296
## pesticide_chemical_classphenoxy 0.9938 -0.5911
## pesticide_chemical_classpyrethroid 0.7816 -0.3542
## pesticide_chemical_classrotenones 0.1117 -0.0909
## pesticide_chemical_classtriazine 0.9176 -0.3910
## pesticide_chemical_classtriazole 0.5878 -0.4856
## pesticide_chemical_classurea 0.1031 -0.0824
## ci.ub
## pesticide_chemical_classB-methoxyacrylates 0.5079
## pesticide_chemical_classcarbamate 0.1992
## pesticide_chemical_classdioxolanes 0.4067
## pesticide_chemical_classneonicotinoid 0.3086
## pesticide_chemical_classorganochlorine 0.1824
## pesticide_chemical_classorganophosphate 0.3287
## pesticide_chemical_classorganophosphate and organochlorine 0.4643
## pesticide_chemical_classphenoxy 0.5958
## pesticide_chemical_classpyrethroid 0.2667
## pesticide_chemical_classrotenones 0.8699
## pesticide_chemical_classtriazine 0.4345
## pesticide_chemical_classtriazole 0.2757
## pesticide_chemical_classurea 0.8921
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnRR_mod_pesticide_zebrafish, mod = "pesticide_chemical_class", data = data_zebrafish,
group = "study_id") # For prediction intervals## name estimate lowerCL upperCL
## 1 B-methoxyacrylates -0.060805783 -0.62954312 0.5079316
## 2 Carbamate -0.449584691 -1.09841739 0.1992480
## 3 Dioxolanes -0.178027511 -0.76277054 0.4067155
## 4 Neonicotinoid -0.037834071 -0.38423049 0.3085623
## 5 Organochlorine -0.157359649 -0.49708734 0.1823680
## 6 Organophosphate 0.040428081 -0.24788452 0.3287407
## 7 Organophosphate and organochlorine -0.082636480 -0.62958332 0.4643104
## 8 Phenoxy 0.002350041 -0.59114149 0.5958416
## 9 Pyrethroid -0.043772802 -0.35423017 0.2666846
## 10 Rotenones 0.389492128 -0.09089444 0.8698787
## 11 Triazine 0.021729537 -0.39103807 0.4344971
## 12 Triazole -0.104966171 -0.48559353 0.2756612
## 13 Urea 0.404844895 -0.08237766 0.8920675
## lowerPR upperPR
## 1 -0.9763273 0.8547157
## 2 -1.4169012 0.5177319
## 3 -1.1035770 0.7475220
## 4 -0.8345197 0.7588515
## 5 -0.9511684 0.6364491
## 6 -0.7327741 0.8136303
## 7 -0.9847830 0.8195100
## 8 -0.9287513 0.9334513
## 9 -0.8255024 0.7379568
## 10 -0.4739247 1.2529090
## 11 -0.8059748 0.8494339
## 12 -0.9171205 0.7071881
## 13 -0.4623940 1.2720838## R2_marginal R2_conditional
## 0.1774022 1.0000000# orchaRd plot
orchaRd::orchard_plot(lnRR_mod_pesticide_zebrafish, group = "study_id", xlab = "lnRR",
data = data_zebrafish, mod = "pesticide_chemical_class", k.pos = "right", colour = FALSE,
fill = FALSE)
Moderate by pesticide chemcial class (lnVR)
# Model
lnVR_mod_pesticide_zebrafish <- rma.mv(yi = lnVR, V = lnVRVCV_zebrafish, random = list(~1 |
study_id, ~1 | assay_id, ~1 | species_latin, ~1 | pesticide), mods = ~pesticide_chemical_class -
1, method = "REML", test = "t", data = data_zebrafish, sparse = TRUE)
# Summary results
summary(lnVR_mod_pesticide_zebrafish)##
## Multivariate Meta-Analysis Model (k = 327; method: REML)
##
## logLik Deviance AIC BIC AICc
## -243.3616 486.7232 518.7232 578.7135 520.5549
##
## Variance Components:
##
## estim sqrt nlvls fixed factor
## sigma^2.1 0.0000 0.0000 24 no study_id
## sigma^2.2 0.2184 0.4673 327 no assay_id
## sigma^2.3 0.0000 0.0000 1 yes species_latin
## sigma^2.4 0.0000 0.0000 21 no pesticide
##
## Test for Residual Heterogeneity:
## QE(df = 314) = 2574.8977, p-val < .0001
##
## Test of Moderators (coefficients 1:13):
## F(df1 = 13, df2 = 314) = 2.1734, p-val = 0.0105
##
## Model Results:
##
## estimate se
## pesticide_chemical_classB-methoxyacrylates -0.0855 0.1344
## pesticide_chemical_classcarbamate -0.5383 0.2902
## pesticide_chemical_classdioxolanes 0.3818 0.2367
## pesticide_chemical_classneonicotinoid 0.0692 0.1114
## pesticide_chemical_classorganochlorine 0.1601 0.1815
## pesticide_chemical_classorganophosphate -0.3035 0.1074
## pesticide_chemical_classorganophosphate and organochlorine -0.0059 0.2931
## pesticide_chemical_classphenoxy 0.0968 0.1868
## pesticide_chemical_classpyrethroid 0.0629 0.0737
## pesticide_chemical_classrotenones 0.1541 0.1923
## pesticide_chemical_classtriazine -0.1653 0.1290
## pesticide_chemical_classtriazole -0.2047 0.0839
## pesticide_chemical_classurea 0.2242 0.1483
## tval df
## pesticide_chemical_classB-methoxyacrylates -0.6360 314
## pesticide_chemical_classcarbamate -1.8548 314
## pesticide_chemical_classdioxolanes 1.6132 314
## pesticide_chemical_classneonicotinoid 0.6212 314
## pesticide_chemical_classorganochlorine 0.8818 314
## pesticide_chemical_classorganophosphate -2.8244 314
## pesticide_chemical_classorganophosphate and organochlorine -0.0202 314
## pesticide_chemical_classphenoxy 0.5182 314
## pesticide_chemical_classpyrethroid 0.8524 314
## pesticide_chemical_classrotenones 0.8015 314
## pesticide_chemical_classtriazine -1.2811 314
## pesticide_chemical_classtriazole -2.4400 314
## pesticide_chemical_classurea 1.5116 314
## pval ci.lb
## pesticide_chemical_classB-methoxyacrylates 0.5253 -0.3499
## pesticide_chemical_classcarbamate 0.0646 -1.1093
## pesticide_chemical_classdioxolanes 0.1077 -0.0839
## pesticide_chemical_classneonicotinoid 0.5349 -0.1500
## pesticide_chemical_classorganochlorine 0.3785 -0.1971
## pesticide_chemical_classorganophosphate 0.0050 -0.5149
## pesticide_chemical_classorganophosphate and organochlorine 0.9839 -0.5827
## pesticide_chemical_classphenoxy 0.6047 -0.2707
## pesticide_chemical_classpyrethroid 0.3946 -0.0822
## pesticide_chemical_classrotenones 0.4235 -0.2242
## pesticide_chemical_classtriazine 0.2011 -0.4191
## pesticide_chemical_classtriazole 0.0152 -0.3697
## pesticide_chemical_classurea 0.1317 -0.0676
## ci.ub
## pesticide_chemical_classB-methoxyacrylates 0.1790
## pesticide_chemical_classcarbamate 0.0327 .
## pesticide_chemical_classdioxolanes 0.8474
## pesticide_chemical_classneonicotinoid 0.2883
## pesticide_chemical_classorganochlorine 0.5172
## pesticide_chemical_classorganophosphate -0.0921 **
## pesticide_chemical_classorganophosphate and organochlorine 0.5709
## pesticide_chemical_classphenoxy 0.4642
## pesticide_chemical_classpyrethroid 0.2079
## pesticide_chemical_classrotenones 0.5325
## pesticide_chemical_classtriazine 0.0886
## pesticide_chemical_classtriazole -0.0396 *
## pesticide_chemical_classurea 0.5161
##
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1mod_results(lnVR_mod_pesticide_zebrafish, mod = "pesticide_chemical_class", data = data_zebrafish,
group = "study_id") # For prediction intervals## name estimate lowerCL upperCL
## 1 B-methoxyacrylates -0.085474240 -0.34991240 0.17896392
## 2 Carbamate -0.538294727 -1.10931408 0.03272462
## 3 Dioxolanes 0.381780671 -0.08386518 0.84742652
## 4 Neonicotinoid 0.069192632 -0.14996161 0.28834688
## 5 Organochlorine 0.160067092 -0.19706926 0.51720344
## 6 Organophosphate -0.303476981 -0.51488652 -0.09206744
## 7 Organophosphate and organochlorine -0.005913603 -0.58268844 0.57086123
## 8 Phenoxy 0.096770206 -0.27068274 0.46422315
## 9 Pyrethroid 0.062855642 -0.08222227 0.20793356
## 10 Rotenones 0.154122479 -0.22422539 0.53247035
## 11 Triazine -0.165250146 -0.41905252 0.08855223
## 12 Triazole -0.204650496 -0.36967288 -0.03962811
## 13 Urea 0.224219978 -0.06764018 0.51608013
## lowerPR upperPR
## 1 -1.0421833 0.8712349
## 2 -1.6206199 0.5440305
## 3 -0.6488458 1.4124071
## 4 -0.8760022 1.0143875
## 5 -0.8262955 1.1464297
## 6 -1.2469062 0.6399523
## 7 -1.0912863 1.0794591
## 8 -0.8933745 1.0869149
## 9 -0.8679571 0.9936684
## 10 -0.8401169 1.1483618
## 11 -1.1190742 0.7885740
## 12 -1.1387796 0.7294786
## 13 -0.7404287 1.1888687## R2_marginal R2_conditional
## 0.124203 1.000000# orchaRd plot
orchaRd::orchard_plot(lnVR_mod_pesticide_zebrafish, group = "study_id", xlab = "lnVR",
data = data_zebrafish, mod = "pesticide_chemical_class", k.pos = "right", colour = FALSE,
fill = FALSE)
## R version 4.2.1 (2022-06-23 ucrt)
## Platform: x86_64-w64-mingw32/x64 (64-bit)
## Running under: Windows 10 x64 (build 22631)
##
## Matrix products: default
##
## locale:
## [1] LC_COLLATE=English_Australia.utf8 LC_CTYPE=English_Australia.utf8
## [3] LC_MONETARY=English_Australia.utf8 LC_NUMERIC=C
## [5] LC_TIME=English_Australia.utf8
##
## attached base packages:
## [1] stats graphics grDevices utils datasets methods base
##
## other attached packages:
## [1] ggsankey_0.0.99999 MuMIn_1.47.5 clubSandwich_0.5.10
## [4] orchaRd_2.0 rotl_3.1.0 ape_5.6-2
## [7] metagear_0.7 metafor_4.0-0 numDeriv_2016.8-1.1
## [10] metadat_1.2-0 Matrix_1.5-1 patchwork_1.2.0
## [13] magrittr_2.0.3 kableExtra_1.4.0 here_1.0.1
## [16] lubridate_1.9.2 forcats_1.0.0 stringr_1.5.0
## [19] dplyr_1.1.0 purrr_1.0.1 readr_2.1.4
## [22] tidyr_1.3.0 tibble_3.1.8 ggplot2_3.5.1
## [25] tidyverse_2.0.0
##
## loaded via a namespace (and not attached):
## [1] nlme_3.1-164 progress_1.2.2 httr_1.4.7 rprojroot_2.0.3
## [5] latex2exp_0.9.6 tools_4.2.1 bslib_0.4.2 utf8_1.2.2
## [9] R6_2.5.1 vipor_0.4.5 colorspace_2.0-3 withr_3.0.1
## [13] tidyselect_1.2.0 prettyunits_1.1.1 emmeans_1.8.5 compiler_4.2.1
## [17] cli_3.4.1 formatR_1.14 xml2_1.3.3 sandwich_3.1-0
## [21] labeling_0.4.2 sass_0.4.5 scales_1.3.0 mvtnorm_1.1-3
## [25] systemfonts_1.0.4 digest_0.6.29 rmarkdown_2.20 svglite_2.1.3
## [29] rentrez_1.2.3 pkgconfig_2.0.3 htmltools_0.5.4 highr_0.10
## [33] fastmap_1.1.0 rlang_1.1.0 rstudioapi_0.14 farver_2.1.1
## [37] jquerylib_0.1.4 generics_0.1.3 zoo_1.8-11 jsonlite_1.8.7
## [41] Rcpp_1.0.9 ggbeeswarm_0.7.1 munsell_0.5.0 fansi_1.0.3
## [45] lifecycle_1.0.3 stringi_1.7.8 multcomp_1.4-25 yaml_2.3.6
## [49] mathjaxr_1.6-0 MASS_7.3-57 grid_4.2.1 parallel_4.2.1
## [53] crayon_1.5.2 rncl_0.8.6 lattice_0.20-45 splines_4.2.1
## [57] hms_1.1.2 knitr_1.42 pillar_1.9.0 tcltk_4.2.1
## [61] estimability_1.4.1 codetools_0.2-18 stats4_4.2.1 XML_3.99-0.11
## [65] glue_1.6.2 evaluate_0.20 vctrs_0.6.0 tzdb_0.3.0
## [69] gtable_0.3.2 cachem_1.0.7 xfun_0.37 xtable_1.8-4
## [73] coda_0.19-4 survival_3.3-1 viridisLite_0.4.2 beeswarm_0.4.0
## [77] timechange_0.2.0 TH.data_1.1-2 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FtcGxpbmcgdmFyaWFuY2VzDQpzYW1wbGluZ192YXJpYW5jZV9zdW1tYXJpZXMgPC0gbGlzdCgNCiAgbG5SUiA9IHN1bW1hcnkobG5SUiR2aSksDQogIGxuQ1ZSID0gc3VtbWFyeShsbkNWUiR2aSksDQogIFNNRCA9IHN1bW1hcnkoU01EJHZpKSwNCiAgVlIgPSBzdW1tYXJ5KGxuVlIkdmkpDQopDQoNCiMgQ2FsY3VsYXRlIHByZWNpc2lvbiBmb3IgZWFjaCBlZmZlY3Qgc2l6ZSBlc3RpbWF0ZSB3aXRoIGNoZWNrcw0KbG5SUiRwcmVjaXNpb24gPC0gaWZlbHNlKGxuUlIkdmkgPiAwLCAxIC8gc3FydChsblJSJHZpKSwgTkEpDQpsbkNWUiRwcmVjaXNpb24gPC0gaWZlbHNlKGxuQ1ZSJHZpID4gMCwgMSAvIHNxcnQobG5DVlIkdmkpLCBOQSkNClNNRCRwcmVjaXNpb24gPC0gaWZlbHNlKFNNRCR2aSA+IDAsIDEgLyBzcXJ0KFNNRCR2aSksIE5BKQ0KbG5WUiRwcmVjaXNpb24gPC0gaWZlbHNlKGxuVlIkdmkgPiAwLCAxIC8gc3FydChsblZSJHZpKSwgTkEpDQoNCg0KIyBNZXJnZSBlYWNoIG9mIHRoZSBlZmZlY3Qgc2l6ZSB3aXRoIHByZWNpc2lvbg0KZWZmZWN0X3NpemVfbWV0cmljc19zZXQgPC0gZGF0YS5mcmFtZSgNCiAgbG5SUiA9IGxuUlIkeWksIGxuUlJ2ID0gbG5SUiR2aSwgbG5SUl9wcmVjaXNpb24gPSBsblJSJHByZWNpc2lvbiwNCiAgbG5WUiA9IGxuVlIkeWksIGxuVlJ2ID0gbG5WUiR2aSwgbG5WUl9wcmVjaXNpb24gPSBsblZSJHByZWNpc2lvbiwNCiAgbG5DVlIgPSBsbkNWUiR5aSwgbG5DVlJ2ID0gbG5DVlIkdmksIGxuQ1ZSX3ByZWNpc2lvbiA9IGxuQ1ZSJHByZWNpc2lvbiwNCiAgU01EID0gU01EJHlpLCBTTUR2ID0gU01EJHZpLCBTTURfcHJlY2lzaW9uID0gU01EJHByZWNpc2lvbiwNCiAgY29udHJvbF9pbXB1dGVkID0gZGF0YSRjb250cm9sX3NkX3JlcG9ydCwgdHJlYXRtZW50X2ltcHV0ZWQgPSBkYXRhJHRyZWF0bWVudF9zZF9yZXBvcnQpDQoNCg0KDQogIyBCaW5kIHRoZSBlZmZlY3Qgc2l6ZSBtZXRyaWNzIHNldCB0byB0aGUgbWFpbiBkYXRhDQpkYXRhIDwtIGNiaW5kKGRhdGEsIGVmZmVjdF9zaXplX21ldHJpY3Nfc2V0KQ0KDQoNCiMgQ2hlY2sgaWYgYGVmZmVjdF9kaXJlY3Rpb25gIGlzICJjaGFuZ2UiIGFuZCBub3QgTkEsIHRoZW4gbXVsdGlwbHkgYGxuUlJgIGJ5IC0xOyBvdGhlcndpc2UsIGtlZXAgb3JpZ2luYWwgYGxuUlJgDQpkYXRhJGxuUlIgPC0gaWZlbHNlKCFpcy5uYShkYXRhJGVmZmVjdF9kaXJlY3Rpb24pICYgZGF0YSRlZmZlY3RfZGlyZWN0aW9uID09ICJjaGFuZ2UiLCANCiAgICAgICAgICAgICAgICAgICAgLTEgKiBkYXRhJGxuUlIsIA0KICAgICAgICAgICAgICAgICAgICBkYXRhJGxuUlIpDQoNCg0KIyBTZWxlY3Qgc3BlY2lmaWMgY29sdW1ucyBpbmNsdWRpbmcgdGhlIG5ldyBwcmVjaXNpb24gY29sdW1ucw0KZWZmZWN0X3NpemVfbWV0cmljc19zZXRfa2FibGUgPC0gZGF0YVssIHdoaWNoKGNvbG5hbWVzKGRhdGEpICVpbiUgYygNCiAgInN0dWR5X2lkIiwgImV4cF9pZCIsICJhc3NheV9pZCIsICJzcGVjaWVzX2VuZ2xpc2giLCAicGVzdGljaWRlIiwgImJlaGF2aW91cl9hc3NheSIsImVmZmVjdF9kaXJlY3Rpb24iLA0KICAibG5SUiIsICJsblJSdiIsICJsblJSX3ByZWNpc2lvbiIsIA0KICAibG5DVlIiLCAibG5DVlJ2IiwgImxuQ1ZSX3ByZWNpc2lvbiIsIA0KICAibG5WUiIsICJsblZSdiIsICJsblZSX3ByZWNpc2lvbiIsIA0KICAiU01EIiwgIlNNRHYiLCAiU01EX3ByZWNpc2lvbiIsIA0KICAiY29udHJvbF9pbXB1dGVkIiwgInRyZWF0bWVudF9pbXB1dGVkIg0KKSldICU+JSBkZnJvdW5kKGRpZ2l0cyA9IDMpDQoNCg0KIyBUYWJsZSBvZiB0aGUgZWZmZWN0IHNpemVzDQoga2FibGUoZWZmZWN0X3NpemVfbWV0cmljc19zZXRfa2FibGUsICJodG1sIikgJT4lDQogICAga2FibGVfc3R5bGluZygiYm9yZGVyZWQiLCBwb3NpdGlvbiA9ICJsZWZ0IikgJT4lDQogICAgc2Nyb2xsX2JveCh3aWR0aCA9ICIyNTAlIiwgaGVpZ2h0ID0gIjgwMHB4IikNCg0KIyBQbG90IHRoZSBkaXN0cmlidXRpb24gb2YgZWZmZWN0IHNpemUgZXN0aW1hdGVzIChsblJSKQ0KbG5SUl9kaXN0X3Bsb3QgPC0gZWZmZWN0X3NpemVfbWV0cmljc19zZXRfa2FibGUgJT4lDQogIGdncGxvdChhZXMobG5SUikpICsNCiAgZ2VvbV9oaXN0b2dyYW0oZmlsbCA9IFJDb2xvckJyZXdlcjo6YnJld2VyLnBhbChuID0gOCwgbmFtZSA9ICJTZXQyIilbMl0sIGNvbCA9ICJibGFjayIsIGJpbndpZHRoID0gMC4xLCBhbHBoYSA9IDAuNCkgKw0KICB0aGVtZV9idygpICsNCiAgdGhlbWUobGVnZW5kLnBvc2l0aW9uID0gIm5vbmUiLA0KICAgICAgICBwbG90LnRpdGxlID0gZWxlbWVudF90ZXh0KGZhY2UgPSAiYm9sZCIsIGhqdXN0ID0gMC41KSwNCiAgICAgICAgYXhpcy50aXRsZS54ID0gZWxlbWVudF90ZXh0KGZhY2UgPSAiYm9sZCIpLA0KICAgICAgICBheGlzLnRpdGxlLnkgPSBlbGVtZW50X3RleHQoZmFjZSA9ICJib2xkIiksDQogICAgICAgIGF4aXMudGV4dC54ID0gZWxlbWVudF90ZXh0KGNvbG9yID0gImJsYWNrIiksDQogICAgICAgIGF4aXMudGV4dC55ID0gZWxlbWVudF90ZXh0KGNvbG9yID0gImJsYWNrIiksDQogICAgICAgIGF4aXMudGlja3MgPSBlbGVtZW50X2xpbmUoY29sb3IgPSAiYmxhY2siKSwNCiAgICAgICAgcGxvdC5jYXB0aW9uID0gZWxlbWVudF90ZXh0KHNpemUgPSAxMCwgY29sb3IgPSAiZ3JheTEwIiwgZmFjZSA9ICJpdGFsaWMiKSkgKw0KICBsYWJzKGNhcHRpb24gPSAiRGlzdHJpYnV0aW9uIG9mIEVmZmVjdCBTaXplIEVzdGltYXRlcyAobG5SUikiLA0KICAgICAgIHggPSAibG5SUiIsDQogICAgICAgeSA9ICJGcmVxdWVuY3kiKQ0KDQpwcmludChsblJSX2Rpc3RfcGxvdCkNCg0KDQogIyBQbG90IHRoZSBkaXN0cmlidXRpb24gb2YgZWZmZWN0IHNpemUgZXN0aW1hdGVzIChsblZSKQ0KbG5WUl9kaXN0X3Bsb3QgPC0gZWZmZWN0X3NpemVfbWV0cmljc19zZXRfa2FibGUgJT4lDQogIGdncGxvdChhZXMobG5DVlIpKSArDQogIGdlb21faGlzdG9ncmFtKGZpbGwgPSBSQ29sb3JCcmV3ZXI6OmJyZXdlci5wYWwobiA9IDgsIG5hbWUgPSAiU2V0MiIpWzNdLCBjb2wgPSAiYmxhY2siLCBiaW53aWR0aCA9IDAuMSwgYWxwaGEgPSAwLjQpICsNCiAgdGhlbWVfYncoKSArDQogIHRoZW1lKGxlZ2VuZC5wb3NpdGlvbiA9ICJub25lIiwNCiAgICAgICAgcGxvdC50aXRsZSA9IGVsZW1lbnRfdGV4dChmYWNlID0gImJvbGQiLCBoanVzdCA9IDAuNSksDQogICAgICAgIGF4aXMudGl0bGUueCA9IGVsZW1lbnRfdGV4dChmYWNlID0gImJvbGQiKSwNCiAgICAgICAgYXhpcy50aXRsZS55ID0gZWxlbWVudF90ZXh0KGZhY2UgPSAiYm9sZCIpLA0KICAgICAgICBheGlzLnRleHQueCA9IGVsZW1lbnRfdGV4dChjb2xvciA9ICJibGFjayIpLA0KICAgICAgICBheGlzLnRleHQueSA9IGVsZW1lbnRfdGV4dChjb2xvciA9ICJibGFjayIpLA0KICAgICAgICBheGlzLnRpY2tzID0gZWxlbWVudF9saW5lKGNvbG9yID0gImJsYWNrIiksDQogICAgICAgIHBsb3QuY2FwdGlvbiA9IGVsZW1lbnRfdGV4dChzaXplID0gMTAsIGNvbG9yID0gImdyYXkxMCIsIGZhY2UgPSAiaXRhbGljIikpICsNCiAgbGFicyhjYXB0aW9uID0gIkRpc3RyaWJ1dGlvbiBvZiBFZmZlY3QgU2l6ZSBFc3RpbWF0ZXMgKGxuVlIpIiwNCiAgICAgICB4ID0gImxuVlIiLA0KICAgICAgIHkgPSAiRnJlcXVlbmN5IikNCg0KcHJpbnQobG5WUl9kaXN0X3Bsb3QpDQpgYGANCg0KIyMgKkRlcGVuZGVudCBlZmZlY3Qgc2l6ZSBlc3RpbWF0ZXMqDQojIyMgKkNyZWF0ZSBwaHlsb2dlbnRpYyB0cmVlKg0KV2UgdXNlZCB0aGUgKnJvdGwqIHBhY2thZ2UgKGh0dHBzOi8vcGVlcmouY29tL3ByZXByaW50cy8xNDcxLykgdG8gcmV0cmlldmUgc3ludGhldGljIHNwZWNpZXMgdHJlZSBmcm9tIE9wZW4gVHJlZSBvZiBMaWZlIChodHRwczovL29wZW50cmVlb2ZsaWZlLm9yZy8pLiANCiANCmBgYHtyfQ0KZGF0YSA8LSBhcy5kYXRhLmZyYW1lKGRhdGEpDQoNCmRhdGEkc3BlY2llc19sYXRpbiA9IGFzLmZhY3RvcihkYXRhJHNwZWNpZXNfbGF0aW4pDQoNCnRheGEgPC0gdG5yc19tYXRjaF9uYW1lcyhuYW1lcyA9IGxldmVscyhkYXRhJHNwZWNpZXNfbGF0aW4pLCBjb250ZXh0ID0gIkFuaW1hbHMiKSAgIyBNYXRjaCBzcGVjaWVzIG5hbWVzIHRvIHRoZSBPcGVuIFRyZWUgb2YgTGlmZSB0YXhvbm9teQ0KDQprYWJsZSh0YXhhKSAgIyBEaXNwbGF5IG1hdGNoZWQgc3BlY2llcywgZW5zdXJpbmcgZWFjaCBzcGVjaWVzIGhhcyBhIHVuaXF1ZSBtYXRjaCBpbiB0aGUgT3BlbiBUcmVlIG9mIExpZmUNCg0KdGF4YSR1bmlxdWVfbmFtZSA8LSBnc3ViKCIgIiwgIl8iLCB0YXhhJHVuaXF1ZV9uYW1lKSAgIyBSZXBsYWNlIHNwYWNlcyBpbiBzcGVjaWVzIG5hbWVzIHdpdGggdW5kZXJzY29yZXMNCg0KcGh5bG9fdHJlZSA8LSB0b2xfaW5kdWNlZF9zdWJ0cmVlKG90dF9pZHMgPSB0YXhhJG90dF9pZCwgbGFiZWxfZm9ybWF0ID0gIm5hbWUiKSAgIyBHZW5lcmF0ZSBhIHBoeWxvZ2VuZXRpYyB0cmVlIGJhc2VkIG9uIHRoZSBPcGVuIFRyZWUgb2YgTGlmZSB0YXhvbm9teQ0KDQpvdHRfaW5fdHJlZSA8LSBvdHRfaWQodGF4YSlbaXNfaW5fdHJlZShvdHRfaWQodGF4YSkpXSAgIyBFbnN1cmUgYWxsIGlkZW50aWZpZXJzIGFyZSBwcmVzZW50IGluIHRoZSB0YXhvbm9teQ0KDQpwaHlsb190cmVlIDwtIHRvbF9pbmR1Y2VkX3N1YnRyZWUob3R0X2lkcyA9IG90dF9pbl90cmVlKSAgIyBHZW5lcmF0ZSBhIHBoeWxvZ2VuZXRpYyB0cmVlIGluY2x1ZGluZyBhbGwgc3BlY2llcyBwcmVzZW50IGluIHRoZSB0YXhvbm9teQ0KDQppcy5iaW5hcnkocGh5bG9fdHJlZSkgICMgQ2hlY2sgaWYgdHJlZSBpcyBiaW5hcnkgDQoNCg0KIyBQbG90IGZvciB0aGUgcGh5bG9nZW5ldGljIHRyZWUNCnBsb3QocGh5bG9fdHJlZSwNCiAgICAgY2V4PSAxLCAjZm9udCBzaXplDQogICAgIGxhYmVsLm9mZnNldCA9LjEsDQogICAgIG5vLm1hcmdpbiA9IFRSVUUpDQoNCiMgQ29tcHV0ZSBicmFuY2ggbGVuZ3RoDQpwaHlsb19icmFuY2hlZCA8LSBjb21wdXRlLmJybGVuKHBoeWxvX3RyZWUsIG1ldGhvZCA9ICJHcmFmZW4iLCBwb3dlciA9IDEpICAjIGNvbXB1dGUgYnJhbmNoIGxlbmd0aHMgdXNpbmcgR3JhZmVuJ3MgbWV0aG9kDQoNCnBoeWxvX2JyYW5jaGVkJHRpcC5sYWJlbCA8LSBzdHJpcF9vdHRfaWRzKHBoeWxvX2JyYW5jaGVkJHRpcC5sYWJlbCwgcmVtb3ZlX3VuZGVyc2NvcmVzID0gRkFMU0UpICAjIHJlbW92ZSBvdHQgSUQgZnJvbSBzcGVjaWVzIG5hbWUgdG8gbWF0Y2ggaXQgdG8gdGhlIGRhdGEgc2V0DQoNCnBoeWxvX21hdHJpeCA8LSB2Y3YocGh5bG9fYnJhbmNoZWQsIGNvciA9IFQpICAjIEdlbmVyYXRlIHZhcmlhbmNlIGNvdmFyaWFuY2UgbWF0cml4IHRvIGNvcnJlbGF0ZSBzcGVjaWVzIHJlbGF0ZWRuZXNzIA0KDQpkYXRhIDwtIGFzLmRhdGEuZnJhbWUoZGF0YSkNCg0KIyBDb252ZXJ0IHNwZWNpZXNfbGF0aW4gdG8gbG93ZXJjYXNlDQpkYXRhIDwtIG11dGF0ZShkYXRhLCBzZWFyY2hfc3RyaW5nID0gdG9sb3dlcihzcGVjaWVzX2xhdGluKSkNCg0KZGF0YSA8LSBsZWZ0X2pvaW4oZGF0YSwgc2VsZWN0KHRheGEsIHNlYXJjaF9zdHJpbmcsIHVuaXF1ZV9uYW1lLCBvdHRfaWQpLCBieSA9ICJzZWFyY2hfc3RyaW5nIikgICMgSm9pbiBkYXRhIHNldHMNCg0KZGF0YSA8LSBkYXRhW2RhdGEkdW5pcXVlX25hbWUgJWluJSBwaHlsb19icmFuY2hlZCR0aXAubGFiZWwsIF0gICMgQ2hlY2sgdGhhdCBzcGVjaWVzIG5hbWVzIGFyZSB3ZWxsIG1hdGNoZWQgd2l0aCB0aGUgcGh5bG9nZW5ldGljIHRyZWUNCg0KDQpkYXRhJHBoeWxvZ2VueSA8LSBkYXRhJHVuaXF1ZV9uYW1lICAjIFJlbmFtZSAndW5pcXVlX25hbWUnIHRvICdwaHlsb2dlbnknIGZvciB0aGUgbW9kZWxzDQoNCg0KYGBgDQoNCiMjIFZhcmlhbmNlIGNvdmFyaWFuY2UgbWF0cmljZXMNCmBgYHtyfQ0KIyBhY2NvdW50IGZvciBzYW1wbGluZyBjb3ZhcmlhbmNlLCBhc3N1bWluZyBlZmZlY3Qgc2l6ZSB3aXRoaW4gc3R1ZGllcyBhcmUgY29ycmVsYXRlZCB3aXRoIHJobyA9IDAuNQ0KIy0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLWxuUlItLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0jDQpkYXRhPC0gZGF0YVshaXMubmEoZGF0YSRsblJSdiksXSANCg0KbG5SUlZDViA8LSBtZXRhZm9yOjp2Y2FsYyh2aSA9IGxuUlJ2LCBjbHVzdGVyID0gZXhwX2lkLCBvYnMgPSBhc3NheV9pZCwgZGF0YSA9IGRhdGEsIHJobyA9IDAuNSkNCg0KbG5SUlZDVjIgPC0gbWV0YWZvcjo6dmNhbGModmkgPSBsblJSdiwgY2x1c3RlciA9IGV4cDJfaWQsIG9icyA9IGFzc2F5X2lkLCBkYXRhID0gZGF0YSwgcmhvID0gMC41KSAjIFNlbnNpdGl2aXR5IGFuYWx5c2lzIHdpdGggYWx0ZXJuYXRpdmUgVkNWDQoNCiMtLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS1sblZSLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tIw0KZGF0YSA8LSBkYXRhWyFpcy5uYShkYXRhJGxuVlJ2KSxdDQoNCmxuVlJWQ1YgPC0gbWV0YWZvcjo6dmNhbGModmkgPSBsblZSdiwgY2x1c3RlciA9IGV4cF9pZCwgb2JzID0gYXNzYXlfaWQsIGRhdGEgPSBkYXRhLCByaG8gPSAwLjUpDQoNCmxuVlJWQ1YyIDwtIG1ldGFmb3I6OnZjYWxjKHZpID0gbG5WUnYsIGNsdXN0ZXIgPSBleHAyX2lkLCBvYnMgPSBhc3NheTJfaWQsIGRhdGEgPSBkYXRhLCByaG8gPSAwLjUpICMgU2Vuc2l0aXZpdHkgYW5hbHlzaXMgd2l0aCBhbHRlcm5hdGl2ZSBWQ1YNCg0KIy0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLWxuQ1ZSLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tIw0KZGF0YSA8LSBkYXRhWyFpcy5uYShkYXRhJGxuQ1ZSdiksXQ0KDQpsbkNWUlZDViA8LSBtZXRhZm9yOjp2Y2FsYyh2aSA9IGxuQ1ZSdiwgY2x1c3RlciA9IGV4cF9pZCwgb2JzID0gYXNzYXlfaWQsIGRhdGEgPSBkYXRhLCByaG8gPSAwLjUpDQoNCiMtLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS1TTUQtLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0tLS0jDQpkYXRhIDwtIGRhdGFbIWlzLm5hKGRhdGEkU01EdiksXQ0KDQpTTURWQ1YgPC0gbWV0YWZvcjo6dmNhbGModmkgPSBTTUR2LCBjbHVzdGVyID0gZXhwX2lkLCBvYnMgPSBhc3NheV9pZCwgZGF0YSA9IGRhdGEsIHJobyA9IDAuNSkNCg0KDQpgYGANCg0KIyAqKlNlbGVjdGlvbiBvZiByYW5kb20tZWZmZWN0IHN0cnVjdHVyZSoqDQoNClNlbGVjdCB0aGUgIm1vc3QgYXBwcm9wcmlhdGUiIHN0cnVjdHVyZSBmb3IgdGhlIHN1YnNlcXVlbnQgc3RhdGlzdGljYWwgbW9kZWxsaW5nLg0KDQpUaGUgcG90ZW50aWFsIHJhbmRvbSBlZmZlY3Qgd2VyZToNCg0KLSAxKSBPYnNlcnZhdGlvbiAoKmFzc2F5X2lkKikgLSBBIHVuaXF1ZSBpZCBmb3IgZWFjaCBwYWlyd2lzZSBjb21wYXJpc29uIGZvciBlZmZlY3Qgc2l6ZSBjYWxjdWxhdGlvbg0KDQotIDIpIENvaG9ydCAoKmV4cF9pZCopIC0gQSB1bmlxdWUgaWQgZm9yIGVhY2ggZXhwb3N1cmUgZ3JvdXAgaW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